Polygenic scores (PGSs) have several limitations. They are confounded with environmental effects on behavior and cannot be used to study how mutations affect brain function and behavior. For this, mutations with large effects, which often arise in only one geographical population are needed. Genome-wide association studies (GWASs), commonly used for identifying mutations, have difficulty detecting these mutations. A strategy that overcomes this challenge is discussed.

Why has the labeled line versus across-fiber pattern debate of taste coding not been resolved? Erickson suggests that the basic tastes concept has no rational definition to test. Similarly, however, taste neuron types, which are fundamental to the across-fiber pattern concept, have not been formally defined, leaving this concept with no rational definition to test. Consequently, the two concepts are largely indistinguishable.

Michael Faraday’s laboratory experiments have dominated traditional histories of the electrical sciences in 1820s and 1830s Britain. However, as this article demonstrates, in the mining region of Cornwall, Robert Were Fox fashioned a very different approach to the study of electromagnetic phenomena. Here, it was the mine that provided the foremost site of scientific experimentation, with Fox employing these underground locations to measure the Earth’s heat and make claims over the existence of subterranean electrical currents. Yet securing philosophical claims cultivated (...) in mines proved challenging for Fox, with metropolitan audiences, including Faraday, loath to give credit to the results of these underground experiments. This article explores how Fox developed a way of modeling his mine experiments, using clay samples, to communicate knowledge from industrial Cornwall to urban centers of elite science. It argues that the mine was an epistemologically complex venue of scientific activity, at once seeming to provide a way of examining nature directly, without recourse to laboratory contrivance, while simultaneously being a place where knowledge claims were hard to verify without access to these physically challenging locations. In exploring Fox’s work, this study contributes to a growing literature of spatial investigation that takes the vertical as its unit of analysis. (shrink)

Updates earlier arguments for the plausibility of the thesis that basic aspects of well being are incommensurable, a thesis central to new classical natural law theory. Responds to objections from Jonathan Crowe and Jason Brennan.

Argues for a framework understanding of the common good, one that does not depend on the existence and operation of the state, in the context of new classical natural law theory.

Excerpt from Heredity, Correlation and Sex Differences in School Abilities: Studies From the Department of Educational Psychology at Teachers College, Columbia University The Relationships between the Different Abilities Involved in the Study of Arithmetic. By W. A. Fox and E. L. Thorndike. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving (...) the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works. (shrink)

Fox, McGee, and Caplan's, in the Summer 1998 issue of CQ, evoked memories and an image.

Conscience plays a crucial role in identifying, applying, and initiating actions chosen as right or wrong. In this paper, we pursue an answer to the question, Can bad conscience, as Nietzsche defines it, be overcome to form the ground for the creation of good conscience? Nietzsche identifies Christianity as the source of that which has to be overcome to help re-define human existence--overcoming self-destructive, bad conscience. To understand whether someone could (or even should) overcome and redefine his or her existence, (...) that is create good conscience like Nietzsche's Ubermensch, it is useful to consider the struggles of Allie Fox, the hero in Peter Weir's movie Mosquito Coast (1986). (shrink)

This book is the outgrowth of a panel of papers on the theme of "memory," presented at the 1987 Annual Meeting of the Buddhism Section of the American Academy of Religion. Four of the contributors to this volume, including Western phenomenologist Edward Casey from SUNY Stony Brook, participated in that panel, though the papers were obviously further developed since that inceptional presentation. The book focusses on the crucial but heretofore almost entirely overlooked topic of memory and remembrance as it (...) appears in the Indian and Tibetan Buddhist traditions. There are 11 papers here, plus an editor's introduction, and though some of them seem to overlap somewhat, none makes any of the others completely redundant or unnecessary. The result is a very thorough and novel treatment of a crucially important subject for Buddhologists, and is further a fine example of Comparative Philosophy. (shrink)

This article offers a fresh assessment of the views of the American paleontologist and evolutionary biologist Stephen Jay Gould on the relation of science and religion. Gould is best known for his celebrated notion of “nonoverlapping magisteria,” which is often seen in somewhat negative terms as inhibiting dialogue. However, as a result of his critique of the unificationist approach to knowledge developed in Edward O. Wilson's Consilience, Gould later made increased use of the more positive notion of a “consilience (...) of equal regard,” which recognized the porous nature of disciplinary divides and the propriety of interdisciplinary dialogue. Gould's final views on the relation of science and religion, set out in The Hedgehog, the Fox, and the Magister's Pox, published after his death, affirms the distinctiveness and autonomy of science and religion on the one hand, while encouraging their constructive dialogue and productive interaction on the other. This should now be seen as Gould's definitive statement on this question. (shrink)

A provocative critique of Western attitudes about the Orient, this history examines the ways in which the West has discovered, invented, and sought to control the East from the 1700s to the present.

An enormous intellectual adventure. In this groundbreaking new book, the American biologist Edward O. Wilson, considered to be one of the world's greatest living scientists, argues for the fundamental unity of all knowledge and the need to search for consilience --the proof that everything in our world is organized in terms of a small number of fundamental natural laws that comprise the principles underlying every branch of learning. Professor Wilson, the pioneer of sociobiology and biodiversity, now once again breaks (...) out of the conventions of current thinking. He shows how and why our explosive rise in intellectual mastery of the truths of our universe has its roots in the ancient Greek concept of an intrinsic orderliness that governs our cosmos and the human species--a vision that found its apogee in the Age of Enlightenment, then gradually was lost in the increasing fragmentation and specialization of knowledge in the last two centuries. Drawing on the physical sciences and biology, anthropology, psychology, religion, philosophy, and the arts, Professor Wilson shows why the goals of the original Enlightenment are surging back to life, why they are reappearing on the very frontiers of science and humanistic scholarship, and how they are beginning to sketch themselves as the blueprint of our world as it most profoundly, elegantly, and excitingly is. (shrink)

Biophilia is Edward O. Wilson's most personal book, an evocation of his own response to nature and an eloquent statement of the conservation ethic. Wilson argues that our natural affinity for life―biophilia―is the very essence of our humanity and binds us to all other living species.

In this imaginative and comprehensive study, Edward Casey, one of the most incisive interpreters of the Continental philosophical tradition, offers a philosophical history of the evolving conceptualizations of place and space in Western thought. Not merely a presentation of the ideas of other philosophers, _The Fate of Place_ is acutely sensitive to silences, absences, and missed opportunities in the complex history of philosophical approaches to space and place. A central theme is the increasing neglect of place in favor of (...) space from the seventh century A.D. onward, amounting to the virtual exclusion of place by the end of the eighteenth century. Casey begins with mythological and religious creation stories and the theories of Plato and Aristotle and then explores the heritage of Neoplatonic, medieval, and Renaissance speculations about space. He presents an impressive history of the birth of modern spatial conceptions in the writings of Newton, Descartes, Leibniz, and Kant and delineates the evolution of twentieth-century phenomenological approaches in the work of Husserl, Merleau-Ponty, Bachelard, and Heidegger. In the book's final section, Casey explores the postmodern theories of Foucault, Derrida, Tschumi, Deleuze and Guattari, and Irigaray. (shrink)

In this imaginative and comprehensive study, Edward Casey, one of the most incisive interpreters of the Continental philosophical tradition, offers a philosophical history of the evolving conceptualizations of place and space in Western thought. Not merely a presentation of the ideas of other philosophers, _The Fate of Place_ is acutely sensitive to silences, absences, and missed opportunities in the complex history of philosophical approaches to space and place. A central theme is the increasing neglect of place in favor of (...) space from the seventh century A.D. onward, amounting to the virtual exclusion of place by the end of the eighteenth century. Casey begins with mythological and religious creation stories and the theories of Plato and Aristotle and then explores the heritage of Neoplatonic, medieval, and Renaissance speculations about space. He presents an impressive history of the birth of modern spatial conceptions in the writings of Newton, Descartes, Leibniz, and Kant and delineates the evolution of twentieth-century phenomenological approaches in the work of Husserl, Merleau-Ponty, Bachelard, and Heidegger. In the book's final section, Casey explores the postmodern theories of Foucault, Derrida, Tschumi, Deleuze and Guattari, and Irigaray. (shrink)

Discusses Indian Buddhist philosophy in three phases of its development.

The Minneapolis Institute of Arts holds the Upper Midwest's most significant permanent collection of fine photographs. Covering the entire history of the medium, from the mid-nineteenth century to the present day. This beautiful book opens with an 1845 salt print by the English inventor William Henry Fox Talbot and closes with a 2002 color portrait by Alec Soth from his series Sleeping by the Mississippi. In between, selected images represent the genres of documentary photography, photojournalism, and street photography. Included are (...) Dorothea Lange's "Migrant Mother" and Arthur Rothstein's "Dust Storm," as well as Edward Weston's "Pepper No. 30" and Ansel Adams's "Moonrise, Hernandez." Commemorating the collecting legacy of Carroll T. Hartwell, the founding curator of the museum's department of photographs, this book reveals Hartwell's critical eye for singular historical photographs and his belief in the influence and vitality of accomplished contemporary photographers. In an introductory essay, Christian A. Peterson recounts the history of the museum's photography collection and Hartwell's indelible imprint on the Minneapolis Institute of Arts. (shrink)

After defining a standard modal language and semantics, we offer some clear examples of logical and analytic truths that are not necessary. These examples: (a) are far simpler than the ones cited in the literature, (b) show that a popular conception of logical truth in modal languages is incorrect, and (c) show that there are contingent truths knowable ``a priori'' that do not depend on fixing the reference of a term.

In this paper I am going to try to indicate my notion concerning the nature and subject-matter of psychology. I am a behaviorist. I hold that psychology does not seek descriptions and intercommunications concerning immediate experience per se. Such descriptions and attempts at direct intercommunications may be left to the arts and to metaphysics. Psychology seeks, rather, the objectively stateable laws and processes governing behavior. Organisms, human and sub-human, come up against environmental stimulus situations and to these stimulus situations they, (...) after longer or shorter intervals of time, behave. The laws and processes determining this their behavior are stateable in objective terms. Even in the cases where the organism is oneself, these determining causal factors can and must—for the purposes of psychology—be stated objectively. It is true that in these latter instances, in which the animal in question is oneself, one may in one's rôle, not of a psychologist, but of an artist or a metaphysician, attempt to describe and convey to another man one's own facts of immediate experience. But such a description and report of immediate experiences, except in so far as this report is itself a form of behavior and therefore like all other behaviors the basis for an investigation of the objective laws and processes underlying it, essentially new to the picture. Experience qua experience, while of concern and interest to the man in the street, the philosopher and the poet, does not enter as such into the laws and equations of psychology,—in so far, at any rate, as psychology is to be considered as a science. (shrink)

First published in 2000. Routledge is an imprint of Taylor & Francis, an informa company.

The problem of the one and the many is central to ancient Greek philosophy, but surprisingly little attention has been paid to Aristotle's treatment of it in the Metaphysics. The Central Books of the Metaphysics are widely recognised as the most difficult portion of a most difficult work. This title aims to examine the Central Books.

Philosophical discussions of the phenomenon that has come to be known as ‘moral luck’ have either dismissed it as illusory or touted it as the evidence for doubting the probative value of our commitment to certain widely avowed views concerning interpersonal assessments of responsibility. In this discussion, we present a third, distinctive interpretation of the moral luck phenomenon. Drawing upon empirically robust results from psychological studies of judgment bias, we argue that the phenomenon of moral luck is demonstrably not illusory. (...) What we suggest, however, is that the phenomenon ought not to be taken to countenance doubts about the standards generally taken to be regulative of assessments of interpersonal responsibility. Rather, its significance lies in foregrounding certain generally unacknowledged obstacles we face in the process of conclusively applying general valid moral standards in making specific judgments of responsibility and desert.1. (shrink)

This paper identifies three positions on the relationship between language and experience, the third of which I was not acquainted with before from my reading. It seems absurd.

Three different notions of concepts are outlined: one derives from Leibniz, while the other two derive from Frege. The Leibnizian notion is the subject of his "calculus of concepts" (which is really an algebra). One notion of concept from Frege is what we would call a "property", so that when Frege says "x falls under the concept F", we would say "x instantiates F" or "x exemplifies F". The other notion of concept from Frege is that of the notion of (...) sense, which played various roles within Frege's theory. This notion of concept can be generalized and, as such, accounts for our intuitive talk of "x's concept of ...", where the ellipsis can be filled in with a name for individual, a property, or a relation, etc. After outlining these three notions, I then discuss how (axiomatic) object theory offers a distinct, precise regimentation of each of the three notions. (shrink)

As organizational leaders worry about the appalling low percentage of people who feel engaged in their work, academics are trying to understand what causes an increase in engagement. We collected survey data from 231 team members from two organizations. We examined the impact of team members’ emotional intelligence (EI) and their perception of shared personal vision, shared positive mood, and perceived organizational support (POS) on the members’ degree of organizational engagement. We found shared vision, shared mood, and POS have a (...) direct, positive association with engagement. In addition, shared vision and POS interact with EI to positively influence engagement. Besides highlighting the importance of shared personal vision, positive mood, and POS, our study contributes to the emergent understanding of EI by revealing EI’s amplifying effect on shared vision and POS in relation to engagement. We conclude by discussing the research and practical implications of this study. (shrink)

In this paper, the author replies to a question raised about theories of nonexistent objects. The question concerns the way names of fictional characters, when analyzed as names which denote nonexistent objects, acquire their denotations. Since nonexistent objects cannot causally interact with existent objects, it is thought that we cannot appeal to a‘dubbing’or a‘baptism’. The question is, therefore, what is the starting point of the chain? The answer is that storytellings are to be thought of as extended baptisms, and the (...) details of this response receive attention in the paper. Once the storytelling is complete, and the characters have been baptized, a priori metaphysical principles linking the storytelling with the realm of nonexistent objects provide the referential, non‐causal connection between the names used in the storytelling and the objects denoted by such names. (shrink)

What happens when we glance around a room? How do we trust what we see in fleeting moments? In The World at a Glance, Edward S. Casey describes how glancing counts for more of human perception than previously imagined. An entire universe is perceived in a glance, but our quick and uncommitted attention prevents examination of these rapid acts and processes. While breaking down this paradox, Casey surveys the glance as an essential way by which we acquaint ourselves with (...) the world. This experiential tour-de-force reveals what happens in a blink of an eye. It will become a landmark study in phenomenology, philosophy, environmental philosophy, and the philosophy of mind. (shrink)

In this paper, the author develops a theory of concepts and shows that it captures many of the ideas about concepts that Leibniz expressed in his work. Concepts are first analyzed in terms of a precise background theory of abstract objects, and once concept summation and concept containment are defined, the axioms and theorems of Leibniz's calculus of concepts (in his logical papers) are derived. This analysis of concepts is then seamlessly connected with Leibniz's modal metaphysics of complete individual concepts. (...) The fundamental theorem of Leibniz's modal metaphysics of concepts is proved, namely, whenever an object x has F contingently, then (i) the individual concept of x contains the concept F and (ii) there is a (counterpart) complete individual concept y which doesn't contain the concept F and which `appears' at some other possible world. Finally, the author shows how the concept containment theory of truth can be made precise and made consistent with a modern conception of truth. (shrink)

This comprehensive account of the history of ancient Greek thought circa 600 to 400 B.C. offers an accessible, nontechnical introduction to Presocratic philosophy.

The traditional separation of philosophy, psychiatry, and neuroscience into distinct academic disciplines has led to several discrete approaches to the mind. In an in-depth discussion of major theories from all of these, and related, disciplines, the author progressively reveals fundamental links between these previously unconnected approaches to human thought and experience. The result is a single, unified theory, perhaps the first to integrate all these fields of thought.

This entry explains Frege's Theorem by using the modern notation of the predicate calculus. Frege's Theorem is that the Dedekind-Peano axioms for number theory are derivable from Hume's Principle, given the axioms and rules of second-order logic. Frege's methodology for defining the natural numbers and for the derivation of the Dedekind-Peano axioms are sketched in some detail.

"You are here, a map declares, but of course you are not, any more than you truly occupy the vantage point into which a landscape painting puts you. How maps and paintings figure and reconfigure space--as well as our place in it--is the subject of Edward S. Casey's study, an exploration of how we portray the world and its many places. Casey's discussion ranges widely from Northern Sung landscape painting to nineteenth-century American and British landscape painting and photography, from (...) prehistoric petroglyphs and medieval portolan charts to seventeenth-century Dutch cartography and land survey maps of the American frontier. From these culturally and historically diverse forays a theory of representation emerges. Casey proposes that the representation of place in visual works be judged in terms not of resemblance, but of reconnecting with an earth and world that are not the mere content of mind or language--a reconnection that calls for the embodiment and implacement of the human subject." -- Book jacket. (shrink)