Histone H3.3 turnover displays distinct dynamics at various genomic elements such as promoters, enhancers, gene bodies, and heterochromatic regions, suggesting that it is differentially regulated according to chromatin context. Incorporation of variant histones into chromatin provides a mechanism to modulate chromatin states in addition to histone modifications. The replication‐independent deposition and replacement of histone variant H3.3, i.e. H3.3 turnover, is mainly associated with transcriptional activity. H3.3 or H3.3‐like histone turnover has been studied in various organisms from yeast to mammals. Here, (...) we review the recent progress on this topic. The diversified turnover profiles of H3.3, and their corresponding underlying mechanisms, may reflect distinct requirements for chromatin accessibility in different biological events. (shrink)

本書稿已獲國家社科基金後期資助項目立項。該書從禮理會通的角度，將經學研究與哲學研究結合起來，並提煉出「禮樂哲學」這一新的學術概念，從禮樂形上學、價值論、實踐觀三個方面對朱子禮學的哲學體系做了較為系統的 詮釋與建構。該書指出，禮、理是朱熹思想的兩個基本面向，禮學是其理學下學實踐的基礎，理學是其禮學的形上依據，二者相融互補，使得朱熹的思想世界在理論與實踐兩個層面都顯得豐滿而自洽。與此同時，朱熹的禮樂哲學 思想也具有充分的現實價值。 馮兵，重慶奉節人，哲學博士，國立華僑大學哲學與社會發展學院教授，博士生導師，國際儒學研究院副院長，《國際孔孟學刊》副主編，國家一級學會「朱子學會」理事，全國名山名川名觀學術委員會高級顧問。畢業於廈門大 學哲學系(2010)，曾赴台灣「中央」研究院文哲所訪學(2015—2016)，主要從事儒家禮樂哲學以及傳統禮樂文化的當代傳承與應用研究。主持國家社科基金項目、教育部人文社科基金項目、教育部社科重大攻關 項目子課題各1項，福建省社科基金重大項目2項，貴州省社科規劃國學單列課題1項，參與國家社科基金重大項目及一般項目、教育部社科基金項目等數項。在《哲學研究》《哲學與文化》(A&HCI)《哲學動態》《中國 哲學史》《學術月刊》《光明日報》等海內外權威及核心學術刊物上發表論文數十篇，出版專著1部。曾獲得過福建省優秀博士學位論文獎、全國聯校教育社科醫學論文獎以及廈門市優秀社科成果獎。先後入選福建省新世紀優秀 人才計劃、華僑大學百名優秀學者成長計劃等人才項目。.

Ben shu fen wu ge zhuan ji,Xuan lu le wang wei guang,Zhang quan jing,Tian xin ming,Liang zhu,Li shen ming,Liu run wei,Zhou xin cheng deng fa biao zai deng qi kan shang de pi pan li shi xu wu zhu yi de wen zhang,Zhi zai yin dao guang da dang yuan gan bu shen ke ren shi li shi xu wu zhu yi de wei hai,Shi zhong jian chi wei wu shi guan,Jian jue fan dui li shi xu wu zhu yi.

本书为清华大学法学院凯原中国法治与义理研究中心主办的'黄帝思想与先秦诸子百家'国际学术研讨会论文集. 本书所收集的二十多篇论文从各个不同的角度和侧面对黄帝思想与诸子百家的关系进行了深入探讨.多数论文认为: 孔子之前中国古代思想的代表人物就是黄帝, 以 "黄帝四经" 为主的经典所表述的思想可以简称为黄帝思想, 就是孔子之前的中国的主流哲学思想, 儒学及诸子百家的源头就是黄帝思想.

Ben shu jie shao le gong zi zhen, wei yuan, yan fu, kang you wei, tan si tong, liang qi chao, chen tian hua, zhang bing lin deng wan qing si xiang jia de zhe xue si xiang.

Yidali si xiang jia Weike de "Xin ke xue" de zhong yao xing bu xia yu Daerwen de "Wu zhong qi yuan", shi mei xue jia Zhu Guangqian wan nian tou ru zui duo jing li wan cheng de yi bu zhong liang ji yi zuo. Zhu Guangqian zai fan yi de tong shi, hai dui "Xin ke xue" jin xing le shen ru yan jiu. zai ben shu zhong, Zhu Guangqian xian shi e yao jie shao le "Xin ke (...) xue" de jing sui, ren wei Weike yan jiu li shi shi qiang diao qiong ben qiu yuan, yi bu luo zi ran fa wei qi dian, lun zheng ren lei ji she hui zhi du de fa zhan; hou you tou shi Weike de shi xue he mei xue, fen xi le wei ke dui xi fang zhe xue de ge xin he Zhongguo mei xue de ju da ying xiang, bing dai chu le Zhu Guangqian zi ji dui zi you ji ren dao zhu yi de zhui qiu. (shrink)

Ben shu bao han zheng zhi dao de de qi yuan he fa zhan, zheng zhi dao de de ben zhi, jie gou he she hui zuo yong deng shi si zhang de nei rong.

Given the rapid growth of music technology, this study reports Chinese pre-service music teachers’ perceptions of musical instrument learning assisted by augmented reality. In this study, we conducted a small-scale case study with six pre-service teachers enrolled in a music teacher training programme at a comprehensive university in China. Participants engaged in semi-structured, face-to-face interviews after hands-on experiences with an AR-based piano learning app. Thematic analysis revealed that the participants were generally aware of the potential of this instructional approach but (...) doubted its efficacy and exhibited weak intention to adopt it in their future classrooms. Implications of the findings for music teacher training are discussed. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Journal of the History of Ideas 63.1 (2002) 1-17 [Access article in PDF] What if the Father Commits a Crime? Rui Zhu Apparently, Socrates and Confucius respond similarly to the question if a son should turn in his father in the case of the father's misdemeanor. When Euthyphro, flaring his pride of his moral impartiality, tells Socrates that he is on his way to report his father because he (...) has thrown one of the household slaves into a ditch and left him bound there until he was dead, Socrates says, "Good Heaven! Certainly, Euthyphro, most men would not know how they could do this and be right. It is not the part of anyone to do this, but of one who is far advanced in wisdom." 1According to Socrates, only a man of high wisdom knows how to prosecute his father righteously, but Euthyphro does not appear to have this wisdom. When his interlocutor observes that an upright man in his state would bear witness against his father if he misappropriates a sheep, Confucius contradicts the interlocutor's understanding of uprightness by speaking in a matter-of-fact tone: "In my country the upright men are of quite another sort. A father will cover up for his son, and a son his father—which incidentally does involve a sort of up—rightness." 2Confucius stands on the same line with Socrates but seems the more radical of the two. Socrates does not directly refute Euthyphro and only suggests that he make sure he understands what he is doing before going any further. Socrates is not only typically Socratic—indirect and suggestive—but also sounds so reasonable that Euthyphro appears in contrast to be a reckless youth who harbors [End Page 1] only a faint understanding of morality. Confucius's response is more rigid, for he categorically dismisses an act of the Euthyphroian kind. He demands that father and son cover up for each other in the case of either one's guilt. Compared to Socrates, Confucius advocates the position that seems a little too strong and leaves no room for justice, while Socrates does not have that problem with justice. This is how we feel about Socrates and Confucius on our first impression. The prima facie observations that we make from the remarks of Socrates and Confucius seem both plain and unproblematic.By embedding these remarks into their respective social or philosophical cultures, this paper will show that our previous observations are not quite accurate. The apparent affinity of the Socratic and Confucian stances belies different underlying moral philosophies. We want to use their comments as bridges to explore the early Greek and Confucian ethics and show how different a picture we see after things are examined within their traditions.The issue of a possible father-son conflict may be treated as a case study of the early Greek (the Heroic era until the age of Socrates) and early Confucian (Confucius and Mencius) morals. There is a strong theme in the early Greek morals that allows, or sometimes demands, a son such as Euthyphro to prosecute his father for the sake of justice, because justice, instead of love (philein) or filial piety, is the governing principle in the early Greek ethics. Confucian ethics is founded on love (human-heartedness), which in turn is extended from the love between father and son. All moral principles including justice are derived from this extension of love. The mutual love of father and son then becomes the governing principle in the case of Confucianism. A Guilty Father: The Greek Motif The question, "What if the father commits a crime?" has a certain realistic aroma to a boy coming of age in the Hesiodic Greek world. That father has to be overcome by son before some relief from strife becomes possible is a familiar theme in Greek literature. In Hesiod's Theogony, Uranus (the sky) incurs hatred from all his newborn children since he hides them in their mother Gaia's womb and does not let them return to the light, for no reason... (shrink)

本书是学习马克思主义哲学史的参考书。书中对学习19世纪和当代马克思主义中存在的40个疑难问题进行了系统的整理和研究。.

该书考察了传统理性主义的理性观从发端、变异到确立、扩展的历史演变,从中对理性与其相关的范畴进行了辨析;分析了由传统理性主义到非理性主义及反理性主义的转向等内容。.

This open access book sheds light on the term gongsheng/kyōsei, which is used in Chinese and Japanese to not only translate “symbiosis” in biology but also broadly deployed in philosophical, social and political contexts. It is a cross-contextual attempt to study the foundation of gongsheng/kyōsei as a philosophy of co-becoming, with exploration of its significance for thinking about the planetary challenges of our times.

This book centers on rethinking foundational values in the era of frontier technologies by tapping into the wisdom of Chinese philosophical traditions. It tries to answer the following questions: How is the essence underpinning humans, nature, and machines changing in this age of frontier technologies? What is the appropriate ethical framework for regulating human–machine relationships? What human values should be embedded in or learnt by AI? Some interesting points emerged from the discussions. For example, the three dominant schools of Chinese (...) thinking–Confucianism, Daoism and Buddhism– invariably reflect non-anthropocentric perspectives and none of them places humanity in a supreme position in the universe. While many Chinese philosophers are not convinced by the prospect of machine intelligence exceeding that of humans, the strong influence of non-anthropocentrism in the Chinese thinking contributed to much less panic in China than in the West about the existential risks of AI. The thinking is that as human beings have always lived with other forms of existence, living with programs or other forms of “beings,” which may become more capable than humans, will not inevitably lead to a dystopia. Second, all three schools emphasize self-restraint, constant introspection, and the pursuit of sage-hood or enlightenment. These views therefore see the potential risks posed by frontier technologies as an opportunity for the humanity to engage in introspection on the lessons learned from our social and political history. It is long overdue that humanity shall rethink its foundational values to take into account a multi-being planetary outlook. This book consists of nine leading Chinese philosophers’ reflections on AI’s impact on human nature and the human society. This is a groundbreaking work, which has pioneered the in-depth intellectual exploration involving traditional Chinese philosophy and frontier technologies and has inspired multidisciplinary and across area studies on AI, philosophy, and ethical implications. (shrink)

With the emergence of online communities, more and more people are participating in online technology communities to meet personalized learning needs. This study aims to investigate whether and how male and female users behave differently in online technology communities. Using text data from Python Technology Community, through LDA (Latent Dirichlet Allocation) model, sentiment analysis and regression analysis, this paper reveals the different topics of male and female users in the online technology community, their sentimental tendencies and activity under different topics, (...) and their correlation and their mutual influence. The results show that: (1) Male users tend to provide information help, while female users prefer to participate in the topic of making friends and advertising. (2) When communicating in the technology community, male and female users mostly express positive emotions, but female users express positive emotions more frequently. (3) Different emotional tendencies of male and female users under different topics have different effects on their activity in the community. The activity of female users is more susceptible to emotional orientation. (shrink)

In a recent article, Arthur Applbaum contributes a new view—legitimacy as a moral power—to the debate over the concept of political legitimacy. Applbaum rejects competing views of legitimacy, in particular legitimacy as a claim-right to have the law obeyed, for mistakenly invoking substantive moral argument in the conceptual analysis, and concludes that “at the core of the concept—what legitimacy is” is only a Hohfeldian moral power. In this article, I contend that: (1) Applbaum’s view of legitimacy, when fully unfolded, refers (...) to more than a mere moral power and should therefore be rejected even by his own standards; (2) Applbaum’s rejection of competing views of legitimacy ultimately relies on a claim that he does not successfully defend, namely, the claim that moral duties are of absolute rather than prima facie force. (shrink)

本书包括四篇内容:第一篇总论;第二篇北宋的理学;第三篇南宋、元代的理学;第四篇明代的理学。.

Gei qing nian de shi er feng xin --Tan mei -- Zuo zhe zi zhuan.

Generally believed that "theory of continuing revolution under the dictatorship of the proletariat" is a "Cultural Revolution" guiding ideology, which in ten years the "Cultural Revolution" period has been widely publicized, has written to the Chinese Communists "nine", "Top Ten", "Eleventh large "by the political report and constitution, but also to write the fourth and fifth National People's Congress meeting adopted constitutional changes, the impact is huge. When it was proposed that "the history of Marxism has set a third great (...) milestone," and after more than ten years later, "since the founding of the party on a number of resolutions on the question of history" has made ​​it a completely different assessment that It is the "leftist" errors and this should be "resolutely corrected." In this paper, the editorial "October Socialist Revolution opened up along the path," CPC "nine", Hua Guofeng, the Third Plenum and "since the founding of the party on a number of resolutions on the question of history," as the coordinates of the tracking the fate of its history and study. q "The Theory on Continuing the Revolution under the Leadership of Proletarians" is commonly regarded as the guiding ideology of the Cultural Revolution. Widely publicized during the decade-long Cultural Revolution, it has been incorporated into the Chinese Communist Party's constitution and the People's Republic of China's constitution for numerous times and has exerted a great influence on the state. By the time it was initially proposed in 1967, it was regarded as' the third landmark in the history of Marxism. But it was subject to a completely different fate more than ten years later as it was labeled "pinko" and was required to he "corrected" in Resolution on Certain Questions in the History of Our Party since the Founding of the People's Republic of China. This paper aims to conduct an investigation of the historical fate of "the Theory on Continuing the Revolution under the Dictatorship of Proletarians" with reference to the following texts: Go Ahead Along the Way Inaugurated by October Socialist Revolution, Report of the Ninth National Congress of the CPC, Hua Guofeng's Talkings, Report of the Third Plenary Session of the 11th Central Committee of the Communist Party of China and Resolution on Certain Questions in the History of Our Party since the Founding of the People's Republic of China. (shrink)

Wie in anderen Ländern, so galt Einstein auch in China als einer der berühmtesten Wissenschaftler schlechthin. In den siebziger Jahren des 20. Jahrhunderts wurden drei Bände Einstein’scher Schriften zusammengestellt, übersetzt und als Einsteins gesammelte Werke veröffentlicht. Diese Bände dienten lange Zeit vielen Chinesen als Hauptwissensquelle über Einstein; sie übten sogar einen bedeutenden ideologischen Einfluss aus. Im Hintergrund dieses herausgeberischen Projekts standen in der Zeit nach 1949 einflussreiche politische Bewegungen im Zusammenwirken mit wissenschaftskritischen Ansätzen, die ein solches Projekt erst möglich machten (...) und die Textauswahl sowie die Herangehensweise bei der Übersetzung und den Druckvorbereitungen beeinflussten. Unter den Herausgebern und Übersetzern kommt Xu Liangying eine besondere und wichtige Rolle zu, denn er war ursprünglich, vor der Gründung der Republik China, ein Untergrundrevolutionär gewesen. Später wurde er Wissenschaftshistoriker. Es vergingen fast 10 Jahre, bis er die Übersetzung der Einstein’schen Schriften fertigstellen konnte, da er gleichzeitig als Bauer auf dem Lande arbeiten musste und während der „Anti-Rechts-Bewegung” „rechts” stand. Die Übersetzung und Veröffentlichung von Einsteins gesammelten Werken in diesem besonderen soziologischen, kulturellen und politischen Kontext bietet viel Stoff für Rückblicke und Aufarbeitungen aus historischer Perspektive. Vor allem die ideologischen, symbolischen Implikationen in Zusammenhang mit Einstein waren ein dominantes Merkmal jener Zeit. (shrink)

Comme dans les autres pays, Einstein a été l’un des scientifiques les plus célèbres en Chine. Dans les années soixante-dix du 20e siècle, trois volumes des OEuvres complètes d’Einstein ont été traduits et publiés en Chine. Pour de nombreux Chinois ces volumes représentaient une source d’informations sur Einstein et une influence idéologique importante. Le contexte politique en est le suivant: après l’an 1949 des mouvements politiques très influents sont nés en Chine, ayant pour objectif la critique des sciences. Ces mouvements (...) ont beaucoup influencé les décisions, la sélection, le progrès ainsi que la manière de traduire et de publier les oeuvres d’Einstein. Parmi les éditeurs et les traducteurs excellait Xu Liangying. Révolutionnaire clandestin avant la mise en place de la République, il est devenu par la suite historien de la science. Il a investi presque dix ans pour terminer la traduction des oeuvres d’Einstein parce qu’ à l’époque il travaillait comme agriculteur pour ses idées de droite pendant la Révolution culturelle. Dans ce contexte sociologique, culturel et politique, la traduction et la publication des OEuvres complètes d’Einstein offre beaucoup de points qui méritent d’être examinés et analysés dans une perspective historique. Surtout, par exemple, les implications idéologiques, symboliques reliés à Einstein et qui ont été les caractéristiques dominantes de cette époque historique. (shrink)

As in other countries, Einstein has been one of the most famous scientists in China. In 1970’s, the three volumes Collection of Einstein in Chinese have been selected, translated and published, which was the main sources for Chinese people knowing Einstein for long time, and even had important ideological influence. However, as the background of it, in China, there were very influential political movements related to criticism of science after 1949, which also influenced the decision, selection, progress and the way (...) of the translating and publishing of Einstein’s works. Among the editors and translators, XU Liangying was a special and important person, who was originally a underground revolutionist before establishment of the Republic, and latterly became a historian of science. He spent nearly ten years to finish the most translation when he was a real peasant in countryside and a “righty” because of the “anti-righty“ movement. During the translating work and the publication of Collection of Einstein in that special social, cultural and political context then, there were many things worth to look back and analyze their meanings by a historical perspective reflection. Especially, the ideological symbolic implication related to the Einstein has been a very dominant characteristic in the history mentioned here. (shrink)

Noise in behavior is often viewed as a nuisance: while the mind aims to take the best possible action, it is let down by unreliability in the sensory and response systems. How researchers study cognition reflects this viewpoint – averaging over trials and participants to discover the deterministic relationships between experimental manipulations and their behavioral consequences, with noise represented as additive, often Gaussian, and independent. Yet a careful look at behavioral noise reveals rich structure that defies easy explanation. First, both (...) perceptual and preferential judgments show that sensory and response noise may potentially only play minor roles, with most noise arising in the cognitive computations. Second, the functional form of the noise is both non-Gaussian and non-independent, with the distribution of noise being better characterized as heavy-tailed and as having substantial long-range autocorrelations. It is possible that this structure results from brains that are, for some reason, bedeviled by a fundamental design flaw, albeit one with intriguingly distinctive characteristics. Alternatively, noise might not be a bug but a feature: indeed, we suggest that noise is fundamental to how cognition works. Specifically, we propose that the brain approximates probabilistic inference with a local sampling algorithm, one that uses randomness to drive its exploration of alternative hypotheses. Reframing cognition in this way explains the rich structure of noise and leads to a surprising conclusion: that noise is not a symptom of cognitive malfunction but plays a central role in underpinning human intelligence. (shrink)