Abstract
Epistemology, confronted with a rapid development of individual branches of science, has been pressed to establish its own status and position as well as to define its relation with science. The multiple perspectives on this issue can be grouped into two major positions: integrism (postulates a close co-existence between epistemology and science) and separatism (argues in favour of a full independence of science and epistemology).In the paper I analyse the two views and try to prove that the debate between integrism and separatism cannot be resolved, as the two approaches belong to different and incompatible philosophical traditions: analytical and transcendental. In the article these issues are examined, and arguments in favour of the separatist view are offered. It is argued for the clear separation of epistemology from science.