Although introns in 5′‐ and 3′‐untranslated regions (UTRs) are found in many protein coding genes, rarely are they considered distinctive entities with specific functions. Indeed, mammalian transcripts with 3′‐UTR introns are often assumed nonfunctional because they are subject to elimination by nonsense‐mediated decay (NMD). Nonetheless, recent findings indicate that 5′‐ and 3′‐UTR intron status is of significant functional consequence for the regulation of mammalian genes. Therefore these features should be ignored no longer.

Everywhere I go, I'm asked if I think the universities stifle writers. My opinion is that they don't stifle enough of them. ---Flannery O'Connor, Mystery and Manners, p. 84, as quoted by Frederick Crews, The Critics Bear it Away, pp. 143--144..

_The Blackwell Guide to the Philosophy of the Social Sciences _collects newly commissioned essays that examine fundamental issues in the social sciences.

This chapter contains sections titled: The Origins of the Philosophy of Social Science Winch's Triad The Legitimation of “Continental” Philosophy Enter Davidson Rational Choice: The Scientization of the Intentional Philosophy of Social Science Today Notes.

In various letters written to Mersenne in 1640 and 1641, Descartes mentions the Summa philosophiae quadrapartita of Eustachius a Sancto Paulo. But nothing that he says would lead us to believe the work an important influence on his thought. Nonetheless, when we turn to the Summa we are immediately struck by what seem to be “Cartesian” elements in its presentation. For example, a distinction is drawn between formal logic and “natural” logic. Formal logic is seen as a convenience in learning (...) the sciences, but natural logic alone is found to be the absolutely essential requirement. And this natural logic is basically a product of the natural light. It is not difficult to see in these passages a foreshadowing of Descartes’ new conception of method. Like Eustachius, he too maintains that the natural functions of the mind are all that we require in the pursuit of truth. But we shall find even more interesting similarities between the two men. (shrink)