In earlier work, representations ofr nucleons were constructed by taking therth Kronecker product of self-representations of the complete homogeneous Lorentz groupL 0 , where these were in the form of a four-component Dirac spinor with components corresponding to the internal symmetries of spin, parity, and charge. When permutations that include every possible exchange of spin, charge, and coordinate, are factored out, the4 F coordinates of flat Minskowski space are contracted by an isometry φ such that energy levels correspond to troughs (...) or saddle points in the new nuclear manifoldM. This is a symmetric space, and using the critical point theory of Morse for the neighborhood of an energy level, it is found that the symmetry σ associated with φ separatesM into just the sets of rotational and vibrational levels. Furthermore, by employing only one parameter, corresponding to the range of energies encountered, good agreement is found with the experimental levels and state labels of 10 B, 10 Be, 10 C, 10 C, and 10 O. The supermultiplet theory of Wigner is a necessary condition for the existence of the states. (shrink)

Products of particlelike representations of the homogeneous Lorentz group are used to construct the degrees of spin angular momentum of a composite system of protons and neutrons. If a canonical labeling system is adopted for each state, a shell structure emerges. Furthermore the use of the Dirac ring ensures that the spin is characterized by half-angles in accord with the neutron-rotation experiment. It is possible to construct a Clebsch-Gordan decomposition to reduce a state of complex angular momentum into simpler states (...) which can be identified with α and β particles, multipole operators, etc. Finally, ground-state energy levels are calculated for all the even-even nuclei by using a differentiable manifold that is spin-graded and gauge-invariant by construction. It is shown that this manifold is Grassmann. (shrink)

Considering only exchange forces, the binding energies and excited states of nuclei up to 24 Mg are predicted to within charge independence, and there is no reason why the model should not be extended to cover all of the elements. A comparison of theory with experiment shows that the energy of one exchange is 2.56 MeV. Moreover, there is an attractive well of depth 30 MeV, corresponding to the helium nucleus, before exchange forces become operative. A possible explanation of the (...) origin of mesons is also presented. (shrink)

Several themes can be identified in the commentaries. The first is that the climbing fibers may have more than one function; the second is that the climbing fibers provide sensory rather than motor signals. We accept the possibility that climbing fibers may have more than one function consequence(s)’ in the title. Until we know more about the function of the inhibitory input to the inferior olive from the cerebellar nuclei, which are motor structures, we have to keep open the possibility (...) that the climbing fiber signals can be a combination of sensory and motor signals. (shrink)

Positive frequency dependent selection is a natural selection regime where the fitness of a phenotype increases with its frequency in the population. Examples can be typically found in the spread of disease tolerance strategies in a population. A characterizing feature of PFDS is that the focal allele may experience favorable selection only when it becomes more frequent in the population, while being selected against when it is rare. In this paper, by applying a solution concept from evolutionary game theory, we (...) hypothesize that the process of emergence of such alleles triggers selection for silence, where the emergence of alleles that can stay unexpressed for a period of time will be favored by selection forces. We illustrate our hypothesis using a mathematical model of a population of single locus diploid organisms with two alleles where a single mutant of an allele that experiences positive frequency dependent selection appears in a population where the other allele is a dominant. The model results show that the longer the silence interval of the new mutant before its expression, the better its chances of getting fixed in the population. However, this effect will be observable only to a certain limit after which further increase in the interval will not have an effect on the expected fixation rate. Two divergences from the simple scenario are also investigated: the nonsynchronous expression of the focal allele and its emergence in a spatial grid limited by a migration bottleneck. In all cases, it is shown that there is an evolutionary pressure inherent in the dynamics of positive frequency dependent selection on the genes to have a delayed expression. It is hypothesized that the regulation systems of such traits will be under selection for either internal silencing mechanisms or to be triggered by an external environmental condition. (shrink)

The purpose of this article is to examine Salvian of Marseilles’ (ca. 400–490 CE) invective in De gubernatione Dei against his Christian audience pertaining to their sexual roles and behaviour as slaveholders. It is argued that rather than considering the oppressive practice of slavery in itself as a reason for moral rebuke and divine punishment, Salvian highlights the social shame that arose from the sexual vices Christian slaveholders committed with their slaves. Salvian forwards three accusations against his opponents that concern (...) slavery and sexual vice. Firstly, he asserts that Christian slaveholders have no self-control. Secondly, the polyamorous relationships slaveholders have with numerous slaves resemble shameful and adulterous unions, namely concubinage and even polygamy. Thirdly, Roman-Christian slaveholders behave in a worse manner than barbarians (i.e. the argument of ethnicity). Each of these accusations is examined in detail in the study. (shrink)

Having to speak words that can potentially abuse the divine connotation of prophetic speech for giving authority to the own manipulative intent poses a daunting challenge to preachers. The metaphorical images triggered by 'DNA' and 'genetic engineering' are deployed in illustrating the ambivalent position in which a prophetic preacher finds himself or herself; ambivalence between anticipation of regeneration at the deepest level of humanity on the one hand, and disquiet about the possibility of forcing a human being against his or (...) her will into meeting certain prescribed expectations on the other hand. In reflecting on possible responses to this ambivalence, the theological positions of two prolific scholars in the research field of Homiletics, Gijs D.J. Dingemans and Charles L. Campbell, are critically considered from the point of view of the relationship between Christology and Pneumatology. In reflecting on theological markers for a sensible response, the author argues for a pneumatology in which the work of the Spirit consists of grafting the very DNA of our humanity and all its faculties into Christ, the only One who can open up the true life that is intended for humanity by divine grace. It will be in the very genes of a prophet to speak graceful words, because the prophet will have seen the wonder of the working of divine grace in his or her own life and will have embraced it willingly and joyfully. (shrink)

While most of us have accepted that our theories are human constructs and approximations of the truth, many of us still think of ‘natural laws ’ as things that exist ‘out there’, and that the work of science is thus the discovery or uncovering of these laws and their expression in mathematical formulae. This notion has serious implications for the science-theology debate. This article challenges the notion that ‘natural laws ’ adequately describe or prescribe nature. It argues that law statements (...) are idealised abstractions that only weakly explain and describe reality, and that mathematics, the ‘language’ of science, is not immutable. It challenges the prescriptive nature of law statements by arguing that we are limited beings who cannot know reality in itself. Our meta-scientific commitments co-determine what and how we think of laws, and the complexity of reality defies human analysis and explanations. Far from having ontic status or being complete and accurate descriptions of reality, natural laws at best mimic the key structures and relationships of the reality they refer to. We would do better to think of reality as an open system of inseparable, interacting and ever-moving components, with the observer an integral part of the system. It is an illusion to believe that these incredibly rich representations of the phenomena are unconstructed isomorphisms we merely discover in the real world. Instead they are constructed – painstakingly so – and there is no evidence that they are isomorphic with structures in the real world. It is an illusion to believe that these incredibly rich representations of the phenomena are unconstructed isomorphisms we merely discover in the real world. Instead they are constructed – painstakingly so – and there is no evidence that they are isomorphic with structures in the real world. William R. Stoeger, S.J. (shrink)

The purpose of this article is to examine Theodoret of Cyrus’s (ca. 393–ca. 457 CE) exposition of LXX Ruth, as found in his Questions on the Octateuch. At the centre of this analysis lies the question of what an early Christian author like Theodoret, who lives in a context where asceticism and sexual renunciation were quite popular (i.e. Christian Syria), does with a complicated text like Ruth, which contains so many explicit nuances about sex, procreation and marriage, as well as (...) various gendered complexities. The article starts by examining briefly the canonisation history of Ruth in early Christianity and some of the main interpretative trends in readings of Ruth by other Christian authors. Then, Theodoret’s interpretation of Ruth is examined, focusing specifically on his Questions on Ruth. The purpose of Ruth as scripture, according to Theodoret, is first delineated, after which Theodoret’s approach to sex and gender in LXX Ruth is examined.Contribution: This article argues that Theodoret transforms the story of Ruth into one that aligns with the moral-philosophical discourse related to sex, marriage and gender of his own time. Theodoret restructures Ruth androcentrically by placing Boaz, the masculine and virtuous male father-figure, at the centre of the story, while at the same time stripping Ruth of any possible agency she might have as a would-be temptress. (shrink)

In this article two homileticians - one from the United States of America (USA) and one from South Africa (SA) - enter into a dialog regarding how the task of prophetic preaching today might be revived, reframed and redefined in light of the Reformation principle of the viva vox Evangelii [living voice of the gospel]. Each author begins by summarising four contemporary approaches to prophetic preaching set forth by Reformed and Lutheran homiletical scholars in their respective contexts. Then each addresses (...) the questions: Where do I particularly see Reformation themes and emphases at work in the work of these homileticians? And how might those Reformation emphases continue to challenge and reframe preaching practices today? Finally, each gives initial reflections on how a comparison between the perspectives deepens and expands his or her understanding of prophetic preaching and its role in church and society. (shrink)

The US neutrino community gathered at the Workshop on the Intermediate Neutrino Program at Brookhaven National Laboratory February 4-6, 2015 to explore opportunities in neutrino physics over the next five to ten years. Scientists from particle, astroparticle and nuclear physics participated in the workshop. The workshop examined promising opportunities for neutrino physics in the intermediate term, including possible new small to mid-scale experiments, US contributions to large experiments, upgrades to existing experiments, R&D plans and theory. The workshop was organized into (...) two sets of parallel working group sessions, divided by physics topics and technology. Physics working groups covered topics on Sterile Neutrinos, Neutrino Mixing, Neutrino Interactions, Neutrino Properties and Astrophysical Neutrinos. Technology sessions were organized into Theory, Short-Baseline Accelerator Neutrinos, Reactor Neutrinos, Detector R&D and Source, Cyclotron and Meson Decay at Rest sessions.This report summarizes discussion and conclusions from the workshop. (shrink)

Code-based cryptography is currently the second most promising post-quantum mathematical tool for quantum-resistant algorithms. Since in 2022 the first post-quantum standard Key Encapsulation Mechanism, Kyber (a latticed-based algorithm), was selected to be established as standard, and after that the National Institute of Standards and Technology post-quantum standardization call focused in code-based cryptosystems. Three of the four candidates that remain in the fourth round are code-based algorithms. In fact, the only non-code-based algorithm (SIKE) is now considered vulnerable. Due to this landscape, (...) it is crucial to update previous results about these algorithms and their functioning. The Fujisaki-Okamoto transformation is a key part of the study of post-quantum algorithms and in this work we focus our analysis on Classic McEliece, BIKE and HQC proposals, and how they apply this transformation to obtain IND-CCA semantic security. Since after security the most important parameter in the evaluation of the algorithms is performance, we have compared the performance of the code-based algorithms of the NIST call considering the same architecture for all of them. (shrink)

Objectives To evaluate whether the requirement of “minimal risk and burden” for paediatric research without direct benefit to the subjects compromises the ability to obtain data necessary for improving paediatric care. To provide evidence-based reflections on the EU recommendation that allows for a higher level of risk. Design and setting Systematic analysis of the approval/rejection decisions made by the Dutch Central Committee on Research involving Human Subjects (CCMO). Review methods The analysis included 165 proposals for paediatric research without direct benefit (...) that were reviewed by the CCMO between January, 2000, and July, 2007. A separate, in-depth analysis of all drug studies included 18 early phase drug studies and nine other drug studies without direct benefit. Results 11 out of 165 studies were definitively rejected because the CCMO did not regard the risk and/or burden to be minimal. In three of these 11 cases (including two early phase drug studies) the requirement of minimal risk and burden was cited as the only reason for rejection. Four other early phase drug studies also involved risks and/or burdens that were not regarded to be minimal but were nevertheless approved. Conclusions The requirement of minimal risk and burden, aiming to protect research subjects, occasionally leads to rejection of protocols. Early phase drug studies relatively often do not comply with the requirement. Committees may find ways to approve important studies that formally should be rejected, but that is not a desirable solution. The regulatory framework should be revised to make such occasional exceptions to the requirement legitimate and transparent. (shrink)

Using the Job Demands-Resources model literature and the life-span theory as scholarly frameworks, we examined the effects of job demands and job resources as mediators in the relationship between bundles of used HRM practices and employee outcomes. In addition, we tested for age differences in our research model. Findings confirmed the hypothesized original 2-factor structure representing maintenance and development HRM practices. Structural Equation Modeling analyses showed that the maintenance HRM bundle related directly and negatively to employee outcomes, without moderating effects (...) of age. However, job resources appeared to mediate this relationship in a positive way as it also did for the development HRM bundle. Whereas this study showed the ‘driving power’ of the actual use of HRM bundles through job resources, regardless of the employee’s age, this study also suggests a ‘dark side’ of HRM. In particular, we found that development HRM bundles may also increase job demands, which, in turn, may result in lower levels of beneficial employee outcomes. These empirical outcomes demonstrate the strength of the driving power eliciting from job resources preceded by any HRM bundle. Moreover, this effect appears to apply to employees of all ages. Our moderated-mediation model appeared robust for several control variables. Overall, this study provides an extension of the well-known Job Demands-Resources model by including maintenance and development bundles of HRM practices used by employees that have a differential effect on job demands and job resources which in turn have an impact on employee outcomes. (shrink)