In _influx & efflux_ Jane Bennett pursues a question that was bracketed in her book _Vibrant Matter_: how to think about human agency in a world teeming with powerful nonhuman influences? “Influx _& _efflux”—a phrase borrowed from Whitman's "Song of Myself"—refers to everyday movements whereby outside influences enter bodies, infuse and confuse their organization, and then exit, themselves having been transformed into something new. How to describe the human efforts involved in that process? What kinds of “I” and “we” (...) can live well and act effectively in a world of so many other lively materialities? Drawing upon Whitman, Thoreau, Caillois, Whitehead, and other poetic writers, Bennett links a nonanthropocentric model of self to a radically egalitarian pluralism and also to a syntax and style of writing appropriate to the entangled world in which we live. The book tries to enact the uncanny process by which we “write up” influences that pervade, enable, and disrupt us. (shrink)

In order to link fine-tuning in physics with spiritual influx, I propose that the highest degree in physics is where ‘ends’ are received in physics. By ends, I refer to what it is that determines the means or causes in physics, and what it is that manages or influences to basis parameters (masses and charge values) of the quantum fields. This is fine-tuning, in the sense that it occurs not just for the whole universe (in the Big Bang, for (...) example), but locally. That is, this fine-tuning is different at each time, and in point in space. Thus this influx can be specific to living organisms, and can occur at all the needed scales and levels in psychology and biology, namely every day and every micros-second of our lives. (shrink)

Historically, the great powers used small nations without a homeland, land and stable moral values as atool for their politics, and the Armenians were one of the few such nations. The Armenians who settled in the Caucasus under the patronageof christian Europe and tsar Russia have repeatedly committed genocide of Azerbaijanis over the past two centuries and facilitated the deportation of the local population. The Armenian atrocities that began in the 19th century and had no analogues in the 20th century (...) were finally brought to an end in the 44-day war and the Azerbaijani army successfully completed the Great Return. Initially, the Armenian occupants were expelled from Nagorno-Karabakh and seven adjacent regions, and now the second stage has begun- a successful return to the ancestral lands of ancient Western Azerbaijan. (shrink)

Before the story can be told, however, some stage-setting is necessary. First, it is important to be clear about the most basic doctrines of Pre-established Harmony, Occasionalism, and Physical Influx. Physical Influx asserts intersubstantial causation amongst finite substances. For instance, when I appear to kick a ball, I really am the cause of the ball's motion. Pre-established Harmony denies intersubstantial causation, but affirms intrasubstantial causation. According to Pre-established Harmony, then, I am not the cause of the ball's motion, (...) but rather the ball is simply causing itself to move. Occasionalism, like Pre-established Harmony, denies intersubstantial causation, but, unlike Pre-established Harmony, it denies intrasubstantial causation as well. Occasionalism typically asserts that God alone, that is, an infinite substance, is the cause of all changes, and thus of the ball's motion. Though there are other ways of defining these causal theories, this way has the advantage that the causal theories form an exhaustive disjunction. (shrink)

Introduction.--Literary history and tradition: Eliot, T. S. Tradition and the individual talent. Trilling, L. The sense of the past. Hassan, I. H. The problem of influence in literary history.--An aesthetics of origins and revisionism: Guillen, C. The aesthetics of literary influence. Block, H. M. The concept of influence in comparative literature. Bloom, H. Clinamen, or poetic misprision. Bate, W. J. The second temple.--Reader as participant: Rosenblatt, L. M. Towards a transactional theory of reading. Holland, N. N. Literature as transformation. Fish, (...) S. E. Literature in the reader. (shrink)

Name der Zeitschrift: Kant-Studien Jahrgang: 109 Heft: 1 Seiten: 9-46.

From the summer of 2015 onwards the high influx of migrants and its effects have dominated the public debate in Europe. At first this influx posed mainly an administrative challenge in host countries such as Austria, Germany, and Sweden. Yet the seemingly incessant flow of migrants from Africa, Asia, and the Middle East, seeking refuge from war or economic deprivation, soon sparked a heated controversy on the possibility of integrating people from very different cultural and religious backgrounds into (...) European societies. Security concerns following the Paris attacks of November 2015 fuelled support for right-wing parties and extremist movements all over Europe. Meanwhile, one EU member state after another introduced restrictive policies contravening the open border policy introduced by the Schengen Agreement in their attempt to shift the administrative burden of handling the migrant crisis onto neighbouring states. The growing anxiety around questions of identity and security was compounded by growing concerns about the economy and welfare. In this essay I delineate the role played by public intellectuals in the debate about this crisis. Drawing on Richard Posner’s broad definition of a public intellectual as someone who writes knowledgeably about ideas for a popular audience on matters of public concern, I focus on how German public intellectuals debated the questions of national identity and the role of the nation-state in the EU migration crisis. (shrink)

The present paper aims to provide an overview on Kant’s dealing with the main theories of causality which were proposed and discussed in his time. The goal is to show that, since the pre-critical period, he has never simply accepted the theories of causality that he could find in second-scholastic sources, but has always tried to develop an original position. Starting from a general acceptance of the theory of the “physical influx”, Kant tries to amend this theory, as it (...) had been roughly provided by Knutzen and Crusius. This emendation is carried out through elements coming from the Leibnitian tradition. But neither in this field Kant totally embraces the Wolffian, as well as the Baumgartenian model. The paper tries also to shed light on the way in which the critical conception of space allows Kant to fulfill his original theory of causality as an amended version of the physical influx. (shrink)

Eric Voegelin’s writings on the historical development of the concept of race in the early 1930s are important to philosophy today in part because they provide a model upon which scholars can further integrate modern philosophy with the critical philosophy of race. In constructing his history, Voegelin’s methodological orientation depends on the centrality of both Kant’s work and the problem of the mind–body union to the concept of race. This essay asks how one might hold these premises if Kant seems (...) to reject the dominant approach to the mind–body union in the mid-eighteenth century, physical influx, and then go on to publish several essays on race that do not thematize that doctrine in any way. I argue that Kant’s racial union of mind and body cannot be understood as an interaction in space, as his contemporaries had presumed. Rather, the union must be approached as a repetition in time. In this way, Kant’s four racial categories are not merely a part of the mind–body problem, but instead each is a veritable mind–body union. This permits the conclusion that ‘race’, as Kant understood it, is a viable solution to the mind–body problem. (shrink)

The influx of religious activities and religious discourse on the Internet has made it pertinent to examine the fundamental roles of language in the expression, presentation, understanding, and advancement of any set of religious beliefs and practices. One main aspect of online religious activities that continues to arrest the attention of scholars is the uniqueness of language used by religious practitioners. For instance, new linguistic strategies and devices have emerged as a result of bending language to suit trends on (...) a new medium. The emergence of the Information Communication Technology in the twenty-first century has also resulted in the manifestation of computer-mediated communication, with its attendant pervasive new forms of language and practices. Nigerian Pentecostal churches have used the Internet, especially the social media such as Facebook and Twitter, in propagating their doctrines. This study identifies emerging lexical trends in the way six Nigerian Pentecostal churches use language in extending their practices on the new media and submits that such innovations are leading up to the birth of a new cyber-variety of Nigerian English. (shrink)

The influx of new groups into society, such as recently established religious groups whose practices differ from societal norms, may disturb relatively stable communities. This instability is exacerbated if these practices contravene long-held fundamental societal tenets, such as the protection of children. This situation now exists in Mexico, where the country's traditional Catholic and secular values clash with those of a religion introduced from the United States, Jehovah's Witnesses. The focal point for these clashes, as it has been elsewhere, (...) is in the bioethics arena. (shrink)

The influx of modernity is approached as a guaranteed right in the economic process. The period is catalogued as a proponent of rationality in Weberian-Habermasian sense, with an adjustment as to ends. Rights adopt four characteristics in the methodological argument of modernity: a) it is calc..

During the influx of neurological research into France from across Europe that took place rapidly in the late 19th century, the philosophy course in lycées was mobilized by education reformers as a means of promulgating the emergent brain sciences and simultaneously steering their cultural resonance. I contend that these linked prongs of philosophy’s public mission under the Third Republic reconciled contradictory pressures to advance the nation’s scientific prowess following its defeat in the Franco-Prussian war of 1870 without dropping France’s (...) distinct tradition of 19th-century spiritualism, which extended from Maine de Biran’s philosophical psychology to Victor Cousin’s official eclectic spiritualism. Between 1874 and 1902, the French Ministry of Public Instruction transformed philosophy into a national project designed to guide the reception of experimental psychology generally and neurology in particular. This article features original archival research on philosophy textbooks and students’ course notes that illuminate the cultural and intellectual impact of these sciences in the fin de siècle from inside the classroom. I argue that the scientific turn in the psychology section of the lycée philosophy course reflected and brought about a distinct philosophical movement that I call ‘scientific spiritualism’. While historians have analysed philosophy instruction as a mechanism used by the Third Republic to secularize students, this article sheds new light on lycée philosophy professors’ campaign to promote scientific spiritualism as a means to advance incipient brain research and pare its reductionist implications. (shrink)

Considering the increasing influx of international students to Chinese universities in recent decades, it is surprising to find that few empirical research, especially longitudinal ones, have been conducted in exploring the motivation of international students in China. To fill up the existing gap, this study explored and tracked international students' motivations dynamically. Mixed research design, such as surveys, reflective journals, and interviews, was employed in this study. Data were collected from 671 international students and three teachers in three Chinese (...) universities in Zhejiang province, mainland China on a longitudinal basis. The present study found that international students' motivation could be discussed with considerations to the following two different phases: preliminary phase before they come to China and follow-up phase when they are in China. This study found that the integrative understanding of the external pulling force and the self-motivated pushing force plays a vital role in answering international students' motivations to China. International students were driven more by the self-motivated pushing force than the external pulling force in selecting China as their study destinations. Moreover, international students experienced motivational changes when their expectations conflict with reality and their positive motivational adjustments and social interaction were important to the sustainability of their academic journey. Moreover, this study provides implications for the government, universities and international students in the aspects of policymaking, education and application. (shrink)

Despite their popularity, dual process accounts of human reasoning and decision-making have come under intense scrutiny in recent years. Cognitive scientists and philosophers alike have come to question the theoretical foundations of the ‘standard view’ of dual process theory and have challenged the validity and relevance of evidence in support of it. Moreover, attempts to modify and refine dual process theory in light of these challenges have generated additional concerns about its applicability and refutability as a scientific theory. With these (...) concerns in mind, this paper provides a critical review of dual process theory in economics, focusing on its role as a psychological framework for decision modeling in behavioral economics and neuroeconomics. I argue that the influx of criticisms against dual process theory challenge the descriptive accuracy of dualistic decision models in economics. In fact, the case can be made that the popularity of dual process theory in economics has less to do with the empirical success of dualistic decision models, and more to do with the convenience that the dual process narrative provides economists looking to explain-away decision anomalies. This leaves behavioral economists and neuroeconomists with something of a dilemma: either they stick to their purported ambitions to give a realistic description of human decision-making and give up the narrative, or they revise and restate their scientific ambitions. (shrink)

ABSTRACTThe massive influx of refugees into Europe in the past few years has given rise to different kinds of challenges among which is the challenge to successfully communicate with newly arrived immigrants. In this article, we will focus on the public service provision sector where quality of service is to a large extent determined by the capability of a service provider and his or her “client” to understand one another. The article centres on a study involving public organisations providing (...) asylum services or healthcare services in the multilingual and multicultural city of Brussels. Several interviews were conducted to gain insight into the communication problems such organisations face, as well as their communication requirements and solutions when providing services to people of different linguistic and cultural backgrounds. We will focus on the types of bridging functions commonly deployed by these organisations in multilingual service encounters and on the motivations for using them. In a... (shrink)

The product market competition has become a global challenge for business organizations in the challenging and competitive market environment in the influx of the COVID-19 outbreak. The influence of products competition on organizational performance in developed economies has gained scholars’ attention, and numerous studies explored its impacts on business profitability. The existing studies designate mixed findings between the linkage of CSR practices and Chinese business firms’ healthier performance in emerging economies; however, the current global crisis due to the coronavirus (...) has made product market completion fierce, which ultimately affects business firms’ performance. This study focuses on this logical global challenge, investigates the rationale, and examines product-market completion impact on firms’ performance operating in the Chinese markets. The study collected data from the annual reports of Chinese business organizations with A-share listing and registered with the database of China Stock Markets and Accounting Research. The study employed a Generalized Method of Moment technique and investigated the connection between product market competition and Chinese firm performance. The empirical analysis of this study highlights the conclusion that market competition positively and significantly affected business firms’ performance. This study specified that product market competition play a dynamic and indispensable role in achieving healthier firm performance in the Chinese markets. This study provides valuable insights on practical implications and future research directions for the scholars to draw interesting results with new study models. (shrink)

The paper aims to sketch Kant’s response to the mind-body problem in his first work, Thoughts on the true estimation of living forces (1747). This is accomplished by first examining the origins of the problem in Descartes, then exploring the traditional responses to the problem, occasionalism, pre-established harmony, and physical influx. Finally, the paper positions Kant as a proponent of physical influx and highlights the unique features and challenges of his perspective.

The senses, or sensory modalities, constitute the different ways we have of perceiving the world, such as seeing, hearing, touching, tasting and smelling. But how many senses are there? How many could there be? What makes the senses different? What interaction takes place between the senses? This book is a guide to thinking about these questions. Together with an extensive introduction to the topic, the book contains the key classic papers on this subject together with nine newly commissioned essays.One reason (...) that these questions are important is that we are receiving a huge influx of new information from the sciences that challenges some traditional philosophical views about the senses. This information needs to be incorporated into our view of the senses and perception. Can we do this whilst retaining our pre-existing concepts of the senses and of perception or do we need to revise our concepts? If they need to be revised, then in what way should that be done? Research in diverse areas, such as the nature of human perception, varieties of non-human animal perception, the interaction between different sensory modalities, perceptual disorders, and possible treatments for them, calls into question the platitude that there are five senses, as well as the pre-supposition that we know what we are counting when we count them as five.This book will serve as an inspiring introduction to the topic and as a basis from which further new research will grow. (shrink)

This paper seeks to address the problem of strangeness within the context of migration in Africa. I draw on historical realities that inform existing international and African discourses on migration. I hope to show that most African countries have unconsciously bought into international arguments that drive the legitimacy of building walls, visible and invisible, and the promotion of stringent migration policies that minimise the influx of African immigrants. I draw on political and philosophical positions of African thinkers like Kwame (...) Nkrumah, among others, in my theorisation of strangeness and the need to dispel the potential negative conception of strangeness within Africa’s migration policies. I juxtapose these positions with Western political theories with the hope of emphasizing African humanism as a key conception worth considering when decolonising borders. (shrink)

Scepticism is a disease in which healthy mental processes run pathologically unchecked. Our cognitive immunity system, designed to protect our conception of the world from harmful errors, turns destructively on that conception itself. Since we have false beliefs, we benefit from the ability to detect our mistakes; removing our errors tends to do us good. Our cognitive immunity system should be able to destroy bad old beliefs, not just prevent the influx of new ones. But that ability sometimes becomes (...) indiscriminate, and destroys good beliefs too. That can happen in several ways. I start by considering two of them. (shrink)

Modern science is big business. Governments, universities, and corporations have invested billions of dollars in scientific and technological research in the hope of obtaining power and profit. For the most part, this investment has benefited science and society, leading to new discoveries, inventions, disciplines, specialties, jobs, and career opportunities. However, there is a dark side to the influx of money into science. Unbridled pursuit of financial gain in science can undermine scientific norms, such as objectivity, honesty, openness, respect for (...) research participants, and social responsibility. In The Price of Truth, David B. Resnik examines some of the important and difficult questions resulting from the financial and economic aspects of modern science. How does money affect scientific research? Have scientists become entrepreneurs bent on making money instead of investigators searching for the truth? How does the commercialization of research affect the public's perception of science? Can scientists prevent money from corrupting the research enterprise? What types of rules, polices, and guidelines should scientists adopt to prevent financial interests from adversely affecting research and the public's opinion of science? (shrink)

In the last decade, reading research has seen a paradigmatic shift. A new wave of computational models of orthographic processing that offer various forms of noisy position or context-sensitive coding have revolutionized the field of visual word recognition. The influx of such models stems mainly from consistent findings, coming mostly from European languages, regarding an apparent insensitivity of skilled readers to letter order. Underlying the current revolution is the theoretical assumption that the insensitivity of readers to letter order reflects (...) the special way in which the human brain encodes the position of letters in printed words. The present article discusses the theoretical shortcomings and misconceptions of this approach to visual word recognition. A systematic review of data obtained from a variety of languages demonstrates that letter-order insensitivity is neither a general property of the cognitive system nor a property of the brain in encoding letters. Rather, it is a variant and idiosyncratic characteristic of some languages, mostly European, reflecting a strategy of optimizing encoding resources, given the specific structure of words. Since the main goal of reading research is to develop theories that describe the fundamental and invariant phenomena of reading across orthographies, an alternative approach to model visual word recognition is offered. The dimensions of a possible universal model of reading, which outlines the common cognitive operations involved in orthographic processing in all writing systems, are discussed. (shrink)

It is not clear why cancer cells choose to disrupt their circadian clock rhythms, and whether such disruption governs a selective fitness and a survival advantage. In this review, I focus on understanding the impacts of clock gene disruption on a simpler model, such as the unicellular cyanobacterium, in order to explain how cancer cells may alter the circadian rhythm to reprogram their metabolism based on their needs and status. It appears to be that the activation of the oxidative pentose (...) phosphate pathway (OPPP) and production of NADPH, the preferred molecule for detoxification of reactive oxygen species, is a critical process for night survival in unicellular organisms. The circadian clock acts as a gatekeeper that controls how the organism will utilize its sugar, shifting sugar influx between glycolysis and OPPP. The circadian clock can thus act as a gatekeeper between an anabolic, proliferative mode and a homeostatic, survival mode. (shrink)

Cinema, thought and time -- Deleuze's cinema books -- Technology -- Essences -- Space and time -- Bergson, time, and life -- The movement-image -- The history of time and space and the history of cinema -- The movement-image and semiotics -- Styles of sign -- The whole of movement -- Image and life -- Becoming-inhuman, becoming imperceptible -- The deduction of the movement-image -- Art and time -- Destruction of the sensory motor apparatus and the spiritual automaton -- Time (...) and money -- Art and history -- Monument -- Framing, territorialization, and the plane of composition -- Politics and the origin of meaning -- Transcending life and the genesis of sense -- Beyond symbolic and imaginary -- Shit and money -- Exchange, gift, and theft -- The fiction of mind -- Collective investment and group fantasy -- The time of man -- The intense germinal influx. (shrink)

The author describes his efforts to become a participant observer while he was a Program Director at the NSF. He describes his plans for keeping track of his reflections and his goals before he arrived at NSF, then includes sections from his reflective diary and comments after he had completed his two-year rotation. The influx of rotators means the NSF has to be an adaptive, learning organization but there are bureaucratic obstacles in the way.

The greatest contemporary challenge in the arena of cognitive neuroscience concerns the relation between consciousness and the brain. Over recent years the focus of work in this area has switched from the analysis of diverse spatial regions of the brain to that of the timing of neural events. It appears that two conditions are necessary in order for neural events to become correlated with conscious experience. First, the firing of assemblies of neurones must achieve a degree of coherence, and, second, (...) reflexive (i.e. top-down, or reentrant) neural pathways must be activated. It does not, of course, follow that such neural activity causes consciousness; it may be, for example, that the neural activity formats the brain to interact with consciousness. The latter possibility is suggested by analysis of mystical texts suggesting that coherence and reflexivity constitute the conditions for the influx of “spirit.” Kabbalistic sources, for example, describe a hierarchy of “brains” in the human and divine realms through which the principles of coherence and reflexivity operate. Whilst the ontological assumptions of such a scheme place it beyond the realm of psychology, parallels with the picture deriving from the contemporary cognitive neuroscience of consciousness are striking. (shrink)

This article critically examines four specific aspects of Avner de Shalit’s book Cities and Immigration. First, it argues that the influx of cosmopolitan migrants, which de Shalit considers unproblematic for destination cities, may in fact pose a challenge to some cities’ ethos, and to the ethos of specific neighbourhoods within cities. Second, it contends that gentrification, contrary to what de Shalit suggests, may sometimes hinder rather than promote social mixing and migrants' integration. Third, it claims that most of the (...) examples of mutual assimilation (de Shalit’s preferred model of inclusion) provided by de Shalit concern superficial interactions and exchanges between members of different groups. This raises both the empirical question of whether deeper forms of mutual assimilation are possible and the normative question of whether they are desirable. Fourth, it takes issue with two concrete policy recommendations advanced by de Shalit: the first involves assessing potential matchings between source and destination cities in order to advise migrants where to move; the second concerns prioritizing immigrants who might be better capable than others of facilitating the integration of future immigrants, due to their values, religion, or country of origin. (shrink)

Embryonic stem cell research has been a source of ethical, legal, and social controversy since the first successful culturing of human ESCs in the laboratory in 1998. The controversy has slowed the pace of stem cell science and shaped many aspects of its subsequent development. This paper assesses the main issues that have bedeviled stem cell progress and identifies the ethical fault lines that are likely to continue.The time is appropriate for such an assessment because the field is poised for (...) a period of rapid development. President Obama has removed the Bush administration’s restrictions on federal funding. A huge influx of federal research funds is in the offing and presumably a more rapid maturing of the science will take place. Stem cell science is also moving into the clinical realm. In March 2009, the Food and Drug Administration approved the first clinical trial with an ESC-derived therapy for spinal cord injuries, an important first step — though by no means a final or a sure one — in moving ESC research out of the laboratory into clinical medicine. Finally, recent work with induced pluripotent stem cells suggests that non-embryonic sources of pluripotent stem cells may one day be routinely available. Such a development will lessen the temperature of the ethical debate while raising other issues. (shrink)

Sufficiently grounding the origin of sense-perceptions in the mind is an issue that has concerned philosophers for a long time, and remains an issue even today. In eighteenth-century Germany prior to the publication of Kant’s Critical philosophy, the two main competing theories to causally ground sense-perceptions were pre-established harmony and physical influx, the latter of which ultimately carried the day. A third option had been around in the seventeenth century: occasionalism. However, historians of philosophy believe this option to have (...) entirely disappeared in the eighteenth century. I will show that this is not the case. In this paper, I focus on one influential German occasionalist: Gottfried Ploucquet (1716–90). Ploucquet not only criticizes Leibniz’s theory of pre-established harmony for providing an ultimately ungrounded, subjective, and arbitrary account of the origin of sense-perceptions, but also presents his own daring alternative: a representationalist-occasionalist theory that locates the objective ground of sense-perceptions in the divine mind. (shrink)

The osmotic activity produced by internal, non‐permeable, anionic nucleic acids and metabolites causes a persistent and life‐threatening cell swelling, or cellular edema, produced by the Gibbs‐Donnan effect. This evolutionary‐critical osmotic challenge must have been resolved by LUCA or its ancestors, but we lack a cell‐physiology look into the biophysical constraints to the solutions. Like mycoplasma, early cells conceivably preserved their volume with Cl−, Na+, and K+‐channels, Na+/H+‐exchangers, and a light‐dependent bacteriorhodopsin‐like H+‐pump. Here, I simulated protocells having these ionic‐permeabilities and inhabiting (...) an oceanic pond before the Great‐Oxygenation‐Event. Protocells showed better volume control and stable resting potentials at lower external pH and higher temperatures, favoring a certain type of extremophile life. Prevention of Na+‐influx at night, with low bacteriorhodopsin activity, required deep shutdown of highly voltage‐sensitive Na+‐channels and extremely selective K+‐channels, two conserved features essential for modern neuronal encoding. The Gibbs‐Donnan effect universality implies that extraterrestrial cells, if they exist, may reveal similar volume‐controlling mechanisms. (shrink)

This paper considers Kant’s conception of force and causality in his early pre-Critical writings, arguing that this conception is best understood by way of contrast with his immediate predecessors, such as Christian Wolff, Alexander Baumgarten, Georg Friedrich Meier, Martin Knutzen, and Christian August Crusius, and in terms of the scientific context of natural philosophy at the time. Accordingly, in the True estimation Kant conceives of force in terms of activity rather than in terms of specific effects, such as motion. Kant’s (...) explicit arguments in the Nova dilucidatio for physical influx are directed primarily against the conception of grounds and existence held by Wolff, Baumgarten, and Meier, and only secondarily against Leibniz. Finally, Kant’s reconciliation of the infinite divisibility of space and the unity of monads in the Physical monadology is designed to respond to objections that could be raised naturally by Wolff and Baumgarten.Author Keywords: Kant; Pre-Critical; Force, Causality; Wolff; Leibniz. (shrink)

Here, an epidemiological model considering pro and anti-vaccination groups is proposed and analyzed. In this model, susceptible individuals can migrate between these two groups due to the influence of false and true news about safety and efficacy of vaccines. From this model, written as a set of three ordinary differential equations, analytical expressions for the disease-free steady state, the endemic steady state, and the basic reproduction number are derived. It is analytically shown that low vaccination rate and no influx (...) to the pro-vaccination group have similar impacts on the long-term amount of infected individuals. Numerical simulations are performed with parameter values of the COVID-19 pandemic to illustrate the analytical results. The possible relevance of this work is discussed from a public health perspective. (shrink)

This article critically questions the commercialization of hospice care and the ethical concerns associated with the industry's movement toward “market-driven medicine” at the end of life. For example, the article examines issues raised by an influx of for-profit hospice providers whose business model appears at its core to have an ethical conflict of interest between shareholders doing well and terminal patients dying well. Yet, empirical data analyzing the experience of patients across the hospice industry are limited, and general claims (...) that end-of-life patient care is inferior among for-profit providers or even that their business practices are somehow unseemly when compared to nonprofit providers cannot be substantiated. In fact, non-profit providers are not immune to potentially conflicting concerns regarding financial viability (i.e., “no margin, no mission”). Given the limitations of existing empirical data and contrasting ideological commitments of for-profit versus non-profit providers, the questions raised by this article highlight important areas for reflection and further study. Policymakers and regulators are cautioned to keep ethical concerns in the fore as an increasingly commercialized hospice industry continues to emerge as a dominant component of the U.S. health care system. Both practitioners and researchers are encouraged to expand their efforts to better understand how business practices and commercial interests may compromise the death process of the patient and patient's family — a process premised upon a philosophy and ethical tradition that earlier generations of hospice providers and proponents established as a trusted, end-of-life alternative. (shrink)

Since the 2010s, popular YouTube channels have used derogatory humour at the expense of gendered and racialised others. Founded upon the perception of an influx of ‘wokeness’ in comedy, these videos mock the mythologised ‘unfunny, angry SJW’ and teach the audience to laugh at enemies of the alt-right. Although empirical research has analysed the algorithmic radicalisation of viewers, few have addressed the role of cultural discourses in disseminating alt-right ideology through online media. Here, the right-wing ‘pipeline’ is understood as (...) a tool of radicalisation that weaponises laughter as a tool of regulations and oppression. This paper analyzes the production of derogatory laughter by studying a network of North American content creators including Russell Peters, Lilly Singh, Jordan Peterson, Steven Crowder, and Matt Walsh, using critical tools from psychoanalysis, social psychology, and critical humour studies. Contrary to the alt-right rhetoric that ‘edgy’ humour is harmless, this paper posits derogatory humour as a tool of marginalisation and domination that reinforces white supremacist and cisnormative patriarchal value systems. (shrink)

This article engages with debates about the status and geographies of colonial science by arguing for the significance of meteorological knowledge making in late nineteenth- and early twentieth-century Mauritius. The article focuses on how tropical storms were imagined, theorized and anticipated by an isolated – but by no means peripheral – cast of meteorologists who positioned Mauritius as an important centre of calculation in an expanding infrastructure of maritime meteorology. Charles Meldrum in particular earned renown in the mid-nineteenth century for (...) theoretical insights into cyclone behaviour and for achieving an unprecedented spatial reach in synoptic meteorology. But as the influx of weather data dried up towards the end of the century, attention turned to developing practices of ‘single-station forecasting’, by which cyclones might be foreseen and predicted not through extended observational networks, but by careful study of the behaviour of one set of instruments in one place. These practices created new moral economies of risk and responsibility, as well as a ‘poetry’, as one meteorologist described it, in the instrumental, sensory and imaginative engagement with a violent atmospheric environment. Colonial Indian Ocean ‘cyclonology’ offers an opportunity to reflect on how the physical, economic and cultural geographies of an island colony combined to produce spaces of weather observation defined by both connection and disconnection, the latter to be overcome not only by infrastructure, but also by the imagination. (shrink)

ABSTRACTRecent years have seen an increase in the influx of asylum-seekers in Scandinavia, and in Denmark this has led to ever-tighter immigration control. This article discusses emerging practices of refugee solidarity and resistance to migration policy in Danish civil society in the wake of what has been referred to as the European refugee crisis. To accomplish this purpose, I analyse how participants in Facebook discussions construe topoi and attitudes when facing the ethical dilemma of respecting the law versus showing (...) concern for humans in need, in line with what Foucault, Michel Foucault: Beyond Structuralism and Hermeneutics. Chicago: The University of Chicago Press) has referred to as ‘ethical self-formation’. This is illustrated through a case study of an incident from September 2015, when a member of a Danish City Council offered private shelter to immigrants on their way to Norway. The incident led to legal proceedings in August 2016 for what the defendant referred to as ‘the offense of helping fellow human beings in need’. The study is informed by Critical Discourse Analysis. Analysing Discourse. Textual analysis for social research. London and New York: Routledge; Wodak, R.. The politics of fear. London and New York: Sage) and governmentality theory. The subject and Power. In H. Dreyfus & P. Rabinow, Michel Foucault: Beyond Structuralism and Hermeneutics. Chicago: The University of Chicago Press; Foucault, M.. Security, Territory, Population: Lectures at the Collège de France 1977–78.. New York: Palgrave Macmillan; McIlvenny, P., Klausen, J. Z., & Lindegaard, L. B.. Studies of Discourse and Governmentality. Amsterdam and Philadelphia: Benjamins). Data include media representations and facebook comments published during 2016. The analytical approach combines topos analysis.. Methods of Critical Discourse Analysis. London: Sage; Wodak, R.. The politics of fear. London and New York: Sage) and appraisal analysis to tease out evaluative meaning. (shrink)

The main topic of the following dissertation is Kant's Third Analogy of Experience, which asserts that one must posit a bond of mutual interaction in order to judge that two substances exist simultaneously. Part One considers the Third Analogy proper and reconstructs two plausible arguments for its main claim. Contrary to the view of most commentators , Kant is entitled to a strong causal notion of mutual interaction. Part Two considers the historical debate between proponents of Pre-established Harmony, Occasionalism, and (...) Physical Influx and how the Third Analogy can be seen as Kant's most developed version of Physical Influx. Thus, we see that Kant's concern with causality is not exhausted by his reply to Hume in the Second Analogy of Experience. For Kant is clearly concerned to attack the rationalist tradition by criticizing Leibniz's and Wolff's Pre-established Harmony, on the one hand, and the Cartesians' and Malebranche's Occasionalism, on the other hand. Part Three considers the argumentative structure of Kant's Metaphysische Anfangsgrunde der Naturwissenschaft and how the Third Analogy relates to this work. Contrary to what one might expect, the MAdN does not proceed by first presupposing a Principle from the first Critique and then substituting in the concept of matter. Rather, its substantial results are obtained through an extended transcendental argument showing how we can have experience of objects of outer sense . Further, we see how the abstract notion of mutual interaction involved in the Third Analogy becomes more specific in the MAdN since two of the most important features of its central notion of matter, namely the capacities of filling a space and of communicating motion, require attractive and repulsive forces and action and reaction, both instances of mutual interaction. These three lines of argument establish that the Third Analogy of Experience both constitutes a crucial part of Kant's position and presents a philosophically plausible view. (shrink)

Our understanding of what exactly needs protected against in order to safeguard a plausible construal of our ‘freedom of thought’ is changing. And this is because the recent influx of cognitive offloading and outsourcing—and the fast-evolving technologies that enable this—generate radical new possibilities for freedom-of-thought violating thought manipulation. This paper does three main things. First, I briefly overview how recent thinking in the philosophy of mind and cognitive science recognises—contrary to traditional Cartesian ‘internalist’ assumptions—ways in which our cognitive faculties, (...) and even our beliefs, can be materially realised by as well as stored non-biologically and extracranially. Second, and taking brain-computer interface technologies (BCIs) and the associated possibility of ‘extended’ beliefs as a reference point, I propose and defend a sufficient condition on freedom-of-thought violating (extended) thought manipulation. On the view proposed, the right not to have one’s thoughts or opinions manipulated is violated if one is (i) caused to acquire non-autonomous propositional attitudes (acquisition manipulation) or (ii) caused to have otherwise autonomous propositional attitudes non-autonomously eradicated (eradication manipulation). The implications of this view are then illustrated through four thought experiments, which map on to four distinct ways—what I call Type 1-Type 4 manipulation—in which, and with reference to the view defended, one’s freedom of thought is plausibly violated. (shrink)

One persistent puzzle in the life sciences is the asymmetric lipid composition of the cellular plasma membrane: while the exoplasmic leaflet is enriched in lipids carrying predominantly saturated fatty acids, the cytoplasmic leaflet hosts preferentially lipids with (poly‐)unsaturated fatty acids. Given the high energy requirements necessary for cells to maintain this asymmetry, the question naturally arises regarding its inherent benefits. In this paper, we propose asymmetry to represent a potential solution for harmonizing two conflicting requirements for the plasma membrane: first, (...) the need to build a barrier for the uncontrolled influx or efflux of substances; and second, the need to form a fluid and dynamic two‐dimensional substrate for signaling processes. We hence view here the plasma membrane as a composite material, where the exoplasmic leaflet is mainly responsible for the functional integrity of the barrier and the cytoplasmic leaflet for fluidity. We reinforce the validity of the proposed mechanism by presenting quantitative data from the literature, along with multiple examples that bolster our model. (shrink)

This paper examines potential responses to emerging ‘climate refugee’ justice issues. ‘Climate refugee’ describes migrants forced to flee their homeland due to losses and damages brought about by events linked to global climate change. These include losses and damages due to extreme weather events, severe droughts and floods, sea-level rise, and an array of pollutant contamination issues. A paradigm case if climate refugeedom is seen in the influx of Peruvian immigrants into various North American cities; seeking asylum after losing (...) access to water and agricultural resources after heavy metals were released through rapid glacial melting and contaminated these necessities in recent years. -/- The main discussion begins with a sketch of the scientific picture of the causal genesis of the apparently worsening “climate refugee crisis” and a concise discussion of new climate science research methods, Probabilistic Event Attribution studies (PEAs), that many agree can be used to determine the liability of certain countries for particular extreme events due to climate change (§1). Against that background, and after providing clarifications regarding the distinction between ‘climate refugee’ and ‘environmental refugee’ (§2), I then discuss key ethical and political issues that are unique to climate refugee cases (§3). Subsequently, I critically assess options for helping climate refugees through existing institutions (§4). I endorse pursuing responses to the most pressing climate refugee problems through the provisions for addressing climate change “losses and damages” in the 2016 UN Framework Convention on Climate Change, “Paris Agreement”; which outlines “risk sharing” protocol that I contend can be used to help climate refugees who are not currently subject to existing UN policies designed to help other types of refugees (e.g. those fleeing from persecution or war). I conclude by outlining a number of ways that PEAs may aid in effectively implementing those losses and damages provisions. (shrink)

The majority of studies on compliment response have investigated CR patterns and norms among different cultural groups and communities. The present study investigated the shifting of CR patterns across generations within the same speech community. To this end, 272 Persian speakers were chosen from among high school students and teachers. A discourse completion task with four complimenting situations was administered. The findings revealed that the new generation of Persian speakers, regardless of their gender, had shifted their CR patterns and overwhelmingly (...) accepted compliments. This change is attributed to the changing interpretations and conceptions of politeness and to the influx of English culture, through exposure to English media, internet, TV series, films, etc., among the new generation of Persian speakers. (shrink)

In recent times, the world has seen an explosion of episodes of forced migration. Whether another state has led the attack, such as Russia’s invasion of Ukraine or by its own state such as Myanmar, ousting the Rohingyas, this international political reality of forced exit can neither be denied nor ignored. Consequent to the international political reality, some states have tightened their borders as they hold nationalist concerns against immigration of such kind. Their concern stems from the philosophy of nationalism (...) which claims the protection of borders and sovereignty in light of the influx of refugees and the burden on the state. This paper aims to elaborate on the interaction of political and legal philosophy related to Liberalism and Nationalism. I put forward the hypothesis that the current reality of international politics - the influx of victims of forced migration such as refugees should be rethought with the application of the philosophy of liberal nationalism. Liberalism and nationalism are two very different moral and political philosophies. Liberal claims protect individual freedom, advocate open borders, and promote equality of all before the law and consent of the governed. Nationalist philosophy promotes the interests of the state, and advocates devotion to the state, its ideology, culture and ethos. In the context of forced migration, the ideas of these disunited philosophies can be utilised to balance and accommodate the concerns of refugees, states and citizens. For this, I will examine the philosophies of liberalism, nationalism and liberal nationalism, which present an inclusive form of nationalism. (shrink)

Clonal expansion of T‐lymphocyte populations results from interactions of antigenic structures presented in combination with accessory cells (macrophages) and antibody recognition sites on the surface of T cells. The resulting activation of a membrane phospholipase C plays a crucial role in lymphocyte responses by releasing diglyceride and PIP3. The released diglyceride activates a cellular protein kinase C while PIP3 stimulates Ca2+ influx. Arachidonic acid released by the action of diglyceride lipase serves as substrate for the synthesis of bioactive eicosanoids (...) (prostaglandins and leukotrienes) which in turn modulate cellular adenyl and guanyl cyclases. The eicosanoids serve as both intra‐ and extra‐cellular signals for lymphocytes, regulating the production and expression of lymphokines and mediating the complex interactions between the monocyte‐macrophage components and helper and suppressor T cells.Aspirin and other anti‐inflammatory drugs stimulate mitogenesis by inhibiting production of the negative modulator prostaglandin E2 in accessory cells and by enhancing the production of the lymphokine 1L‐2 by producer T‐cells. (shrink)