One challenge for those reading methodological debates in low consensus fields is determining the outcome when participants do not share standards. When parties to a debate do not agree on the standards to be used in assessing their arguments (i.e., quality), it may be useful to ask first if parties’ contributions meet their own expectations (i.e., integrity). Most protocols for review of qualitative research specify some form of quality assessment. These protocols normally require some test of internal coherence. Coherence is (...) also relevant when describing the match between a rebuttal and the argument it answers. In 2019,Nursing Inquirypublished a critique and rebuttal of the methods used by the Joanna Briggs Institute. In this essay, we attempted to use the Joanna Briggs Institute's own quality assessment standards to assess their rebuttal of this fundamental critique. We found it possible to use the Joanna Briggs Institute's own quality assessment standards to assess this rebuttal, and we found that JBI's rebuttal did not meet their own standards. (shrink)

We motivate the possibility of using notions and methods derived from quantum physics, and more specifically from the research field known as ‘quantum cognition’, to optimally model different situations in the field of medicine, its decision-making processes and ensuing practices, particularly in relation to chronic and rare diseases. This also as a way to devise alternative approaches to the generally adopted double-blind gold standard.

This book offers an empirical and theoretical account of the mode of governance that characterizes the Bologna Process. In addition, it shows how the reform materializes and is translated in everyday working life among professors and managers in higher education. It examines the so-called Open Method of Coordination as a powerful actor that uses “soft governance” to advance transnational standards in higher education. The book shows how these standards no longer serve as tools for what were once human organizational, national (...) or international, regulators. Instead, the standards have become regulators themselves – the faceless masters of higher education. By exploring this, the book reveals the close connections between the Bologna Process and the EU regarding regulative and monitoring techniques such as standardizations and comparisons, which are carried out through the Open Method of Coordination. It suggests that the Bologna Process works as a subtle means to circumvent the EU’s subsidiarity principle, making it possible to accomplish a European governance of higher education despite the fact that education falls outside EU’s legislative reach. The book’s research interest in translation processes, agency and power relations among policy actors positions it in studies on policy transfer, policy borrowing and globalization. However, different from conventional approaches, this study draws on additional interpretive frameworks such as new materialism. (shrink)

. This paper follows the journey of two small fluid units throughout the nineteenth century in Anglo-American medicine and pharmacy, explaining how the non-uniform “drop” survived while the standardized minim became obsolete. I emphasize two roles these units needed to fulfill: that of a physical measuring device, and that of a rhetorical communication device. First, I discuss the challenges unique to measuring small amounts of fluid, outlining how the modern medicine dropper developed out of an effort to resolve problems with (...) the “minimometer,” which measured minims. Second, I explain how drops, utilized in “the open drop method” of administering general anesthesia, effectively communicated a gradual process and epistemically valuable heuristic to the audience of practitioners, whose attention to individual medical outcomes was important for verifying the proper dosage. The standardized minim was never able to achieve success as the drop’s intended replacement; the non-uniform drop better served the relevant epistemic goals within the practical contexts for which these units were designed. The surprising historical trajectory of drops should cause us to question the common equivocation of “standardization” with “progress” in the history and philosophy of measurement. This study also exemplifies how examining non-standard measurement practices can be instructive for better understanding the role and function of standardization within epistemology of measurement. (shrink)

Explains why the debate initiated by Stephen Lloyd Smith’s plea to jettison the so-called ‘Standard Account of Method’ ––the conventional wisdom of how research philosophy and methodology ought to be taught to management students––is of the utmost importance to the teaching of management studies in British universities. Identifies a fully-developed presentation of the SAM framework in a well-considered and widely-used textbook––‘Research Methods for Managers’ by John Gill and Phil Johnson––and demonstrates that the book’s argument is both logically and scholarly (...) defective. Identifies the SAM as a form of dogmatic rationalism; one that is oblivious to the possibility of applying deductive inference in the service of a critical rationalism. Outlines the logical role of deductive testing in empirical research and demonstrates that there need be no great divide between nomothetic and ideographic research problems once appropriate distinctions are drawn between different forms of explanation. Nonetheless, questions the relevance of these research problems to the concerns of practising managers by highlighting the contrast, as made by philosophers, between social science and social technology. Concludes that the continued presentation and defence of the SAM, as the conventional wisdom of how research philosophy and methodology ought to be taught to management students, is thoroughly lamentable. (shrink)

We motivate the possibility of using notions and methods derived from quantum physics, and more specifically from the research field known as ‘quantum cognition’, to optimally model different situations in the field of medicine, its decision-making processes and ensuing practices, particularly in relation to chronic and rare diseases. This also as a way to devise alternative approaches to the generally adopted double-blind gold standard.

We propose a set theory, called NRFST, in which the Cantorian axiom of infinity is negated, and a new notion of infinity is introduced via non standard methods, i. e. via adequate notions of standard and internal, two unary predicates added to the language of ZF. After some initial results on NRFST, we investigate its relative consistency with respect to ZF and Kawai's WNST.

The claims of RCTs to be the gold standard rest on the fact that the ideal RCT is a deductive method: if the assumptions of the test are met, a positive result implies the appropriate causal conclusion. This is a feature that RCTs share with a variety of other methods, which thus have equal claim to being a gold standard. This paper describes some of these other deductive methods and also some useful non-deductive methods, including the hypothetico-deductive (...) method. It argues that with all deductive methods, the benefit that the conclusions follow deductively in the ideal case comes with a great cost: narrowness of scope. This is an instance of the familiar trade-off between internal and external validity. RCTs have high internal validity but the formal methodology puts severe constraints on the assumptions a target population must meet to justify exporting a conclusion from the test population to the target. The paper reviews one such set of assumptions to show the kind of knowledge required. The overall conclusion is that to draw causal inferences about a target population, which method is best depends case-by-case on what background knowledge we have or can come to obtain. There is no gold standard. (shrink)

The standard account of method (SAM) describes business and management research as a choice between “two traditions”: “qualitative “phenomenological” interpretivism” and “quantitative ‘scientific’ positivism”; each the enemy of the other. Students assemble “advantages and disadvantages” of each, pledge their allegiance, or a preference for “mixed method” (wishing for a “truce” in the “paradigm war”). In our increasingly Fordist academies, these variants attract grade-weightings of typically 20%, defined by “marking schemes” which are also standardised. Fordism is the management strategy of standardisation, (...) deskilling, low unit-cost, simple assembly and central control. We argue that SAM “Fordises” the intellect and confounds our experience that inquiry entails the greatest customisation humanly possible. Moreover, unlike Ford’s River Rouge plant, SAM is plagued by faults: thousands of category mistakes caused by collapsing unrelated methodological dimensions into one simple-looking yet multiply mistaken dichotomy. Happily, natural language facilitates myriad methodological distinctions which untutored inquirers articulate with more facility, pluralism and precision than SAM. By providing better labelling for their easy instincts, naïve inquirers can recognise and revel in what they did not know. (shrink)

The standard account of method (SAM) describes business and management research as a choice between “two traditions”: “qualitative “phenomenological” interpretivism” and “quantitative ‘scientific’ positivism”; each the enemy of the other. Students assemble “advantages and disadvantages” of each, pledge their allegiance, or a preference for “mixed method” (wishing for a “truce” in the “paradigm war”). In our increasingly Fordist academies, these variants attract grade-weightings of typically 20%, defined by “marking schemes” which are also standardised. Fordism is the management strategy of standardisation, (...) deskilling, low unit-cost, simple assembly and central control. We argue that SAM “Fordises” the intellect and confounds our experience that inquiry entails the greatest customisation humanly possible. Moreover, unlike Ford’s River Rouge plant, SAM is plagued by faults: thousands of category mistakes caused by collapsing unrelated methodological dimensions into one simple-looking yet multiply mistaken dichotomy. Happily, natural language facilitates myriad methodological distinctions which untutored inquirers articulate with more facility, pluralism and precision than SAM. By providing better labelling for their easy instincts, naïve inquirers can recognise and revel in what they did not know. (shrink)

The claims of RCTs to be the gold standard rest on the fact that the ideal RCT is a deductive method: if the assumptions of the test are met, a positive result implies the appropriate causal conclusion. This is a feature that RCTs share with a variety of other methods, which thus have equal claim to being a gold standard. This paper describes some of these other deductive methods and also some useful non-deductive methods, including the hypothetico-deductive (...) method. It argues that with all deductive methods, the benefit that the conclusions follow deductively in the ideal case comes with a great cost: narrowness of scope. This is an instance of the familiar trade-off between internal and external validity. RCTs have high internal validity but the formal methodology puts severe constraints on the assumptions a target population must meet to justify exporting a conclusion from the test population to the target. The paper reviews one such set of assumptions to show the kind of knowledge required. The overall conclusion is that to draw causal inferences about a target population, which method is best depends case-by-case on what background knowledge we have or can come to obtain. There is no gold standard. (shrink)

Clinical ethics consultation (CEC) has become all about right technique. When we encounter a case of conflict or confusion, clinical ethicists are expected to deploy a standardized, repeatable, and rationally defensible method for working toward a recommendation and/or consensus. While it has been noted previously that our techniques of CEC often foreclose on its internal goods, there remains an assumption that we must just find the _right_ efficient technique and the problem would be solved. In this paper, I question that (...) assumption, arguing that any standardized, identically repeatable model of CEC will pull us counterproductively away from ethical reflection, and toward the values of modern _techne_: primarily efficiency, efficacy, and repeatability. This is because standardized techniques of CEC pull the dynamism of being into what Catherine Pickstock calls “identical repetition,” a technologized ontology, which is fundamentally at odds with what being is. And, since ethics is a search for the good of being, avoiding the ontological heart of being severely restricts ethics. (shrink)

Research studies demonstrate wide variation in how physicians diagnose and treat patients with similar medical conditions and suggest that at least some of the variation reflects inefficiencies and unnecessary medical costs. Health care researchers are actively examining ways to reduce variations in practice through standardization of medicine to reduce the cost of treatment and ensure the quality of outcomes. The most widely accepted form of this standardization is Evidence Based Best Practices. Furthermore, financial health care providers such as (...) hospitals and managed care organizations are investigating methods to tie resource usage to medical protocols in their efforts to monitor and control health care costs. Such proposals are contentious because they report on physicians' medical practice behaviors and such reports could potentially be used to influence their clinical behaviors. The intent of this exploratory study was to examine physicians' perceptions about linking a standard costing system to EBBP guidelines. The authors interviewed nine practicing physicians asking each physician to respond to the question, 'As a physician working in a hospital environment, what are your reactions to and concerns with combining standard costing techniques with EBBP?' The interviews were in-depth and free form in nature. The physicians' responses were recorded and analyzed using Grounded Theory Methodology. Using this methodology the field data was categorized into two major themes. The most important theme centered on ethics and the second theme was concerned with the implementation and use of a standard cost system in regard to EBBP. If physicians' worries about ethical dilemmas and implementation issues are not resolved, then it is likely that doctors would be unwilling to participate in any efforts to develop or use a standard cost-reporting system in medicine. While this study was exploratory in nature, it should provide future guidance to accountants, health care researchers and health care providers about physicians' issues with the use of standard costing methods in medicine. (shrink)

On a traditional view, the primary role of a mathematical proof is to warrant the truth of the resulting theorem. This view fails to explain why it is very often the case that a new proof of a theorem is deemed important. Three case studies from elementary arithmetic show, informally, that there are many criteria by which ordinary proofs are valued. I argue that at least some of these criteria depend on the methods of inference the proofs employ, and (...) that standard models of formal deduction are not well-equipped to support such evaluations. I discuss a model of proof that is used in the automated deduction community, and show that this model does better in that respect. (shrink)

Nanomaterials have attracted much interest in the medical field and related applications as their distinct properties in the nanorange enable new and improved diagnosis and therapies. Owing to these properties and their potential interactions with the human body and the environment, the impact of nanomaterials on humans and their potential toxicity have been regarded a very significant issue. Consequently, nanomaterials are the subject of a wide range of cutting-edge research efforts in the medical and related fields to thoroughly probe their (...) potential beneficial utilizations and their more negative effects. We posit that the lack of standardization in the field is a serious shortcoming as it has led to the establishment of methods and results that do not ensure sufficient consistency and thus in our view can possibly result in research outputs that are not as robust as they should be. The main aim of this article is to present how NanoDiaRA, a large FP7 European multidisciplinary project that seeks to investigate and develop nanotechnology-based diagnostic systems, has developed and implemented robust, standardized methods to support research practices involving the engineering and manipulation of nanomaterials. First, to contextualize this research, an overview of the measures defined by different regulatory bodies concerning nanosafety is presented. Although these authorities have been very active in the past several years, many questions remain unanswered in our view. Second, a number of national and international projects that attempted to ensure more reliable exchanges of methods and results are discussed. However, the frequent lack of publication of procedures and protocols in research can often be a hindrance for sharing those good practices. Subsequently, the efforts made through NanoDiaRA to introduce standardized methods and techniques to support the development and utilization of nanomaterials are discussed in depth. A series of semi-structured interviews were conducted with the partners of this project, and the interviews were analyzed thematically to highlight the determined efforts of the researchers to standardize their methods. Finally, some recommendations are made toward the setting up of well-defined methods to support the high-quality work of collaborative nanoparticle-based research and development projects and to enhance standardization processes. (shrink)

Pluralism about scientific method is more-or-less accepted, but the consequences have yet to be drawn out. Scientists adopt different methods in response to different epistemic situations: depending on the system they are interested in, the resources at their disposal, and so forth. If it is right that different methods are appropriate in different situations, then mismatches between methods and situations are possible. This is most likely to occur due to method bias: when we prefer a particular kind (...) of method, despite that method clashing with evidential context or our aims. To explore these ideas, we sketch a kind of method pluralism which turns on two properties of evidence, before using agent-based models to examine the relationship between methods, epistemic situations, and bias. Based on our results, we suggest that although method bias can undermine the efficiency of a scientific community, it can also be productive through preserving a diversity of evidence. We consider circumstances where method bias could be particularly egregious, and those where it is a potential virtue, and argue that consideration of method bias reveals that community standards deserve a central place in the epistemology of science. (shrink)

Enzyme engineering allows to explore sequence diversity in search for new properties. The scientific literature is populated with methods to create enzyme libraries for engineering purposes, however, choosing a suitable method for the creation of mutant libraries can be daunting, in particular for the novices. Here, we address both novices and experts: how can one enter the arena of enzyme library design and what guidelines can advanced users apply to select strategies best suited to their purpose? Section I is (...) dedicated to the novices and presents an overview of established and standard methods for library creation, as well as available commercial solutions. The expert will discover an up‐to‐date tool to freshen up their repertoire (Section I) and learn of the newest methods that are likely to become a mainstay (Section II). We focus primarily on in vitro methods, presenting the advantages of each method. Our ultimate aim is to offer a selection of methods/strategies that we believe to be most useful to the enzyme engineer, whether a first‐timer or a seasoned user. (shrink)

In evidence-based medicine (EBM), methodology has become the central means of determining the quality of the evidence base. The “gold standard” method, the randomised, controlled trial (RCT), imbues medical research with an ethos of disinterestedness; yet, as this essay argues, the RCT is itself a rhetorically interested construct essential to medical-professional boundary work. Using the example of debates about methodology in EBM-oriented research on complementary and alternative medicine (CAM), practices not easily tested by RCTs, I frame the problem of method (...) as a fundamentally rhetorical problem, situated within a boundary drama, and deeply rooted in the discursive practices of science and medicine. The genre of the RCT report, for example, idealises the research process and can tilt the course of arguments about CAM, while the notion of efficacy can function as a rhetorically mobile boundary object that can redefine the very terms of debate. I suggest herein that arguments about method in CAM debates can productively be read, metonymically, as expressions of more general anxieties in medicine about knowledge and evidence, community values, and professional boundaries; as such, these debates can illuminate some of the rhetorical dimensions of EBM. (shrink)

Non-standard models were introduced by Skolem, first for set theory, then for Peano arithmetic. In the former, Skolem found support for an anti-realist view of absolutely uncountable sets. But in the latter he saw evidence for the impossibility of capturing the intended interpretation by purely deductive methods. In the history of mathematics the concept of a nonstandard model is new. An analysis of some major innovations–the discovery of irrationals, the use of negative and complex numbers, the modern concept of (...) function, and non-Euclidean geometry–reveals them as essentially different from the introduction of non-standard models. Yet, non-Euclidean geometry, which is discussed at some length, is relevant to the present concern; for it raises the issue of intended interpretation. The standard model of natural numbers is the best candidate for an intended interpretation that cannot be captured by a deductive system. Next, I suggest, is the concept of a wellordered set, and then, perhaps, the concept of a constructible set. One may have doubts about a realistic conception of the standard natural numbers, but such doubts cannot gain support from non-standard models. Attempts to utilize non-standard models for an anti-realist position in mathematics, which appeal to meaning-as-use, or to arguments of the kind proposed by Putnam, fail through irrelevance, or lead to incoherence. Robinson’s skepticism, on the other hand, is a coherent position, though one that gives up on providing a detailed philosophical account. The last section enumerates various uses of non-standard models. (shrink)

This paper responds to the commentaries from Stacy Carter and Alan Cribb. We pick up on two main themes in our response. First, we reflect on how the process of setting standards for empirical bioethics research entails drawing boundaries around what research counts as empirical bioethics research, and we discuss whether the standards agreed in the consensus process draw these boundaries correctly. Second, we expand on the discussion in the original paper of the role and significance of the concept of (...) ‘integrating’ empirical methods and ethical argument as a standard for research practice within empirical bioethics. (shrink)

We examine Paul Halmos’ comments on category theory, Dedekind cuts, devil worship, logic, and Robinson’s infinitesimals. Halmos’ scepticism about category theory derives from his philosophical position of naive set-theoretic realism. In the words of an MAA biography, Halmos thought that mathematics is “certainty” and “architecture” yet 20th century logic teaches us is that mathematics is full of uncertainty or more precisely incompleteness. If the term architecture meant to imply that mathematics is one great solid castle, then modern logic tends to (...) teach us the opposite lesson, namely that the castle is floating in midair. Halmos’ realism tends to color his judgment of purely scientific aspects of logic and the way it is practiced and applied. He often expressed distaste for nonstandard models, and made a sustained effort to eliminate first-order logic, the logicians’ concept of interpretation, and the syntactic vs semantic distinction. He felt that these were vague, and sought to replace them all by his polyadic algebra. Halmos claimed that Robinson’s framework is “unnecessary” but Henson and Keisler argue that Robinson’s framework allows one to dig deeper into set-theoretic resources than is common in Archimedean mathematics. This can potentially prove theorems not accessible by standard methods, undermining Halmos’ criticisms. (shrink)

This paper explores the distinctive features of the critical agenda associated with the ‘Social Life of Methods’. I argue that although this perspective can be associated with the increasing interest, often associated with scholars in Science and Technology Studies, to reflect on how methods can become objects of inquiry, it also needs to be rooted in the current crisis of positivist methods. I identify the challenge for positivism in terms of the decreasing ability of its procedures to (...) effectively organize increasingly ‘lively’ sources of standardized data, which can now be assembled using aesthetic registers. In developing this argument, I dispute the idea that this development is due to historical shifts linked to the way that methodological devices are playing an increasingly significant role in contemporary social life, which might be argued by writers such as Thrift or Castells. I also argue that by opening up issues of method to the aesthetic, we also recast the relationship between theory and method, pointing to the exhaustion of a certain kind of cultural theory within the social sciences. I contextualize these issues by considering how methods are implicated in the intellectual differentiation between scientific and humanities expertise. Rather than conceiving the ‘Social Life of Methods’ in terms of the rise of instrumentalist modes of governance, it is preferable to place it within the dialectic of transparency and the relationship between the implicit and explicit. These issues are addressed through introducing the papers in the special issue. (shrink)

This thesis provides an introduction to the physics of the Standard Model and beyond, and to the methods used to analyse Large Hadron Collider (LHC) data. The 'hierarchy problem', astrophysical data and experiments on neutrinos indicate that new physics can be expected at the now accessible TeV scale. This work investigates extensions of the Standard Model with gravitons and gravitinos (in the context of supergravity). The production of these particles in association with jets is studied as one of the (...) most promising avenues for researching new physics at the LHC. Advanced simulation techniques and tools, such as algorithms allowing the computation of Feynman graphs and helicity amplitudes are first developed and then employed. (shrink)

Definition of the problem In medicine, as well as in other disciplines, computer science expertise is becoming increasingly important. This requires a culture of interdisciplinary assessment, for which medical ethics committees are not well prepared. The use of big data and artificial intelligence (AI) methods (whether developed in-house or in the form of “tools”) pose further challenges for research ethics reviews. Arguments This paper describes the problems and suggests solving them through procedural changes. Conclusion An assessment that is interdisciplinary (...) from the outset appears to be more suitable than having two commissions with different expertise. However, this would require that the composition of medical ethics committees be altered. In addition, the article recommends initial measures to be taken during research ethics reviews of big data and AI projects in order to consolidate the review process and ensure standardization of the criteria. (shrink)

Changing Methods is a collection of original essays by feminist practitioners, scholars, and activists. The authors show why "the method question" has moved to the top of many feminist research and interpretive research strategies, and engage in thinking about how ideas and actions have developed within complex social circumstances. The essays in this book challenge the tradition that has allowed abstracted, formalized versions of the ideas and experiences of privileged white men to set standards for how everyone should conduct (...) themselves. The authors use new-found knowledge to displace the dominant ideology constructed around race, class, gender, and heterosexual privilege, and then propose innovative feminist-informed analyses of subjects as diverse as political change, critical linguistics, child care, religious studies, and violence against women. (shrink)

ABSTRACT In recent years there has been intense debate regarding the level of medical care provided to ‘standard care’ control groups in clinical trials in developing countries, particularly when the research sponsors come from wealthier countries. The debate revolves around the issue of how to define a standard of medical care in a country in which many people are not receiving the best methods of medical care available in other settings. In this paper, we argue that additional dimensions of (...) the standard of care have been hitherto neglected, namely, the structure and efficiency of the national health system. The health system affects locally available medical care in two important ways: first, the system may be structured to provide different levels of care at different sites with referral mechanisms to direct patients to the appropriate level of care. Second, inefficiencies in this system may influence what care is available in a particular locale. As a result of these two factors locally available care cannot be equated with a national ‘standard’. A reasonable approach is to define the national standard of care as the level of care that ought to be delivered under conditions of appropriate and efficient referral in a national system. This standard is the minimum level of care that ought to be provided to a control group. There may be additional moral arguments for higher levels of care in some circumstances. This health system analysis may be helpful to researchers and ethics committees in designing and reviewing research involving standard care control groups in developing country research. (shrink)