Physicians and patients rely on medical journals as trusted sources of medical information. Unfortunately, conflicts of interest may undermine the credibility of the medical literature. Improved policies and practices at journals should address the conflicts of interest of authors, reviewers, editors, and journals. Medical journals should manage and eliminate conflicts, not just improve the disclosure of financial relationships.

Physicians and patients rely on medical journals as trusted sources of medical information. Unfortunately, in multiple instances conflicts of interest have undermined the credibility of the medical literature.The primary sources of conflict of interest at medical journals are authors, reviewers, editors, and journals. Consider these examples.

Although informed consent is important in clinical research, questions persist regarding when it is necessary, what it requires, and how it should be obtained. The standard view in research ethics is that the function of informed consent is to respect individual autonomy. However, consent processes are multidimensional and serve other ethical functions as well. These functions deserve particular attention when barriers to consent exist. We argue that consent serves seven ethically important and conceptually distinct functions. The first four functions pertain (...) principally to individual participants: (1) providing transparency; (2) allowing control and authorization; (3) promoting concordance with participants' values; and (4) protecting and promoting welfare interests. Three other functions are systemic or policy focused: (5) promoting trust; (6) satisfying regulatory requirements; and (7) promoting integrity in research. Reframing consent around these functions can guide approaches to consent that are context sensitive and that maximize achievable goals. (shrink)

Different types of consent are used to obtain human biospecimens for future research. This variation has resulted in confusion regarding what research is permitted, inadvertent constraints on future research, and research proceeding without consent. The National Institutes of Health Clinical Center's Department of Bioethics held a workshop to consider the ethical acceptability of addressing these concerns by using broad consent for future research on stored biospecimens. Multiple bioethics scholars, who have written on these issues, discussed the reasons for consent, the (...) range of consent strategies, and gaps in our understanding, and concluded with a proposal for broad initial consent coupled with oversight and, when feasible, ongoing provision of information to donors. This article describes areas of agreement and areas that need more research and dialogue. Given recent proposed changes to the Common Rule, and new guidance regarding storing and sharing data and samples, this is an important and tim.. (shrink)

Contribución de eruditos autores sobre aspectos trascendentales de la teoría pura del derecho. Esta obra debe verse como una expresión de esa renovada ocupación con los problemas de la doctrina de Kelsen.

Winner of the Los Angeles Times Book Prize With a new preface by the author In his most powerful and important book, renowned psychiatrist Robert Jay Lifton presents a brilliant analysis of the crucial role that German doctors played in the Nazi genocide. Now updated with a new preface, The Nazi Doctors remains the definitive work on the Nazi medical atrocities, a chilling exposé of the banality of evil at its epitome, and a sobering reminder of the darkest side (...) of human nature. (shrink)

El profesor Robert Walter, el más eminente representante de la Teoría Pura del Derecho en nuestro tiempo, estudia en "Hans Kelsen, la Teoría Pura del Derecho y el problema de la justicia" y "Normas y enunciados sobre normas", los dos textos que componen esta obra, los puntos centrales del pensamiento filosófico y jurídico de Hans Kelsen.

Se resume en esta obra el vasto y complejo sistema teórico-jurídico de Hans Kelsen, el jurista más grande de nuestro siglo. La doctrina de Kelsen y en particular su Teoría Pura del Derecho han conocido muchas vicisitudes y ataques debidos más a prejuicios políticos y racistas que a una verdadera confrontación con sus tesis. El autor enfatiza en el hecho de que la doctrina jurídica de Kelsen no es una teoría terminada y archivada sino en permanente desarrollo, una teoría a (...) cuya ulterior construcción están convocados todos los juristas. (shrink)

En el debate entre el positivismo y el no-positivismo el argumento del relativismo tiene un papel fundamental. Tal y como es presentado, por ejemplo, por Hans Kelsen, este argumento señala, en primer lugar, que una conexión necesaria entre el derecho y la moral presupone la existencia de elementos morales objetivos, absolutos y necesarios, y, en segundo lugar, que estos elementos morales objetivos, absolutos y necesarios no existen. Mi respuesta a esto es que los elementos morales absolutos, objetivos y necesarios existen, (...) porque los derechos humanos existen, y éstos existen porque son fundamentables. In the debate between positivism and non-positivism the argument from relativism plays a pivotal role. The argument from relativism, as put forward, for instance, by Hans Kelsen, says, first, that a necessary connection between law and morality presupposes the existence of absolute, objective, or necessary moral elements, and, second, that no such absolute, objective, or necessary moral elements exist. My reply to this is that absolute, objective, or necessary moral elements do exist, for human rights exist, and human rights exist because they are justifiable. (shrink)

A partir de la comprensión de la tesis del caso especial como un intento por dar cuenta de la doble vertiente de la argumentación jurídica Alexy se propone defender esta tesis frente a las críticas tomadas en consideración o realizadas por Jürgen Habermas en su libro Facticidad y validez. En primer lugar, Alexy defiende su tesis frente a la crítica que sostiene que las limitaciones que existen en los procedimientos judiciales excluirían su comprensión en términos de teoría del discurso. En (...) segundo lugar, el autor hace hincapié en que la tesis del caso especial que él defiende implica que la argumentación jurídica ha de entenderse como un caso especial del discurso práctico general y no meramente del discurso moral tal y como es definido por Habermas. Y por último, defiende la tesis del caso especial contra la objeción de que los argumentos prácticos generales cambiarían su carácter al pasar a formar parte del Derecho; para ello propugna concebir de manera procedimental la integración de los argumentos prácticos generales en el contexto jurídico. (shrink)

Desde una perspectiva histórica se intenta aportar elementos que clarifiquen la problemática sobre la mundialización y la confrontación de las culturas jurídicas. Así, por una parte, se ofrece una interrogación acerca de la manera en que se practica la teoría del derecho en el mundo anglosajón y en el continental europeo, lo cual conduce a poner en cuestión su pretensión de universalidad. Por otra parte se analiza y discute el estatus y la pertinencia de ciertas teorías del derecho, como la (...) del legal origins theory, que afirman la superioridad del common law sobre el resto de las culturas jurídicas. Se destaca además la necesidad de introducir la dimensión sociológica para la comprensión del fenómeno jurídico. (shrink)

Kant says there is a duty to exit the state of nature, to enter into a civil state. He says this is a duty of right, not a duty of virtue. The article discusses the argument he gives to support this view, as well as the contemporary discussion on the relationship between this duty of right and the categorical imperative. The discussion is full of implications. Particularly significant is the view of the Kantian state emerging from it, which challenges the (...) conventional account: instead of a state designed to protect pre-existing individual property rights, property rights are seen as something resulting from the very constitution of the state. (shrink)

La pregunta si Wittgenstein fue un filósofo liberal ha recibido menos atención que la de si fue un filósofo conservador, pero, como Robert Greenleaf Brice ha defendido recientemente, hay muchos indicios de liberalismo en algumas de sus observaciones, y algunos filósofos, como Richard Eldridge, han sostenido que hay un cierto tipo de liberalismo que se sigue de la filosofía de su última etapa. Richard Rorty ha sacado también conclusiones liberales a partir de la perspectiva filosófica que se basa en (...) la obra de Wittgenstein y Alice Crary ha sugerido que las lecciones aprendidas de su propria interpretación de Wittgenstein "reflejan en formas de vida social que incorporan los ideales de la democracia liberal". (shrink)

ABSTRACT: This paper highlights the difference between Lilian Bermejo-Luque’s account of warrants with the quite different accounts of warrants offered by Toulmin, Hitchcock, and myself, and lays out some of the reasons why I think a “Toulminesque” account of warrants captures crucial aspects of arguing more adequately than her account does.RESUMEN: Este artículo subraya la diferencia entre el análisis de los garantes que nos propone Lilian Bermejo-Luque con los de Toulmin, Hitchcok y el mío propio. Presento algunas razones por las (...) que pienso que un análisis toulminiano de los garantes capta mejor que el suyo algunos aspectos cruciales de la argumentación. (shrink)

Resumen: Tanto Perry Anderson como Alex Callinicos y Terry Eagleton han desarrollado un trabajo cultural y filosófico sobresaliente. Sin embargo, los tres han malinterpretado la obra de Ludwig Wittgenstein. La concepción de la filosofía de Wittgenstein no está en tensión con la filosofía marxista en el modo en el que ellos lo sugirieron y Wittgenstein no cometió los errores que le atribuyeron Anderson, Callinicos e Eagleton. Los marxistas se beneficiarían si consideraran más seriamente la obra de Wittgenstein porque ello los (...) ayudaría a comprender más claramente la naturaleza de los problemas epistemológicos y metafísicos como así también los ayudaría a fortalecer y complementar sus propias concepciones de las confusiones filosóficas. En este trabajo examinaré los errores de sus interpretaciones de Wittgenstein y espero también poder proporcionar alguna indicación de las razones por las cuales Wittgenstein es considerado por muchos como el filósofo más importante del siglo XX. (shrink)

This article gives a brief analysis of the concept of aesthetic profundity, and gives examples of its deployment in European Romanticism, and in various important works of Indian, Chinese and Japanese aesthetic theory. It is srgued that the idea of profundity is most readily deployed in the context of metaphysics which regard the real as having a non-obvious but inexhaustible depth. This is a case of a major logical similarity between European and oriental aesthetic beliefs.

The analysis of relations between morals and rituals show how morals are not unconditional. Ethics are refereed to an ethos which has a continuity with its ritual origin, and, at the same time, ethics are expressed in rituals which constitutes our Lebenswelt.

En este ensayo se examina de manera crítica el desarrollo de la filosofía analítica y, en particular, de la filosofía analítica latinoamericana. Se propone que esta última adopte un giro político y uno pedagógico con el fin de recuperar su espíritu original y reconectarse con la tradición intelectual latinoamericana. This essay is a critical examination of the development of analytic philosophy and, in particular, of Latin American analytic philosophy. It is argued that the latter ought to adopt a political and (...) pedagogical turn in order to recover its original spirit and to be reconnected to Latin American intelectual tradition. (shrink)

Los intentos más recientes de repensar las normas democráticas están ejemplificados por dos pensadores franceses contemporáneos. Pierre Rosavallon critica los movimientos de protesta y trata de institucionalizar sus fuerzas. Jacques Rancière, por otra parte, ha definido notoriamente la política democrática de forma que se da sólo en momentos en los que se re-imagina caóticamente el orden existente. Su enfoque se revela de forma que reclama más atención hacia las normas razonables de ese orden de lo que el propio Rancière admite. (...) Tales normas constituyen un modelo de la democracia disidente, y puede inspirarse en los radicales populares de la era de la fundación americana. (shrink)

Desafíos ambientales como aquellos que enfrenta la región del Cabo de Hornos en Chile, superan la competencia de cualquier marco disciplinario. Las aproximaciones interdisciplinarias al conocimiento, combinando la pericia de varias disciplinas, como también las perspectivas transdisciplinarias de los sectores público y privado, requieren un elemento unificador que permita integrar perspectivas tan dispares. El campo de la filosofía, que tradicionalmente ha ofrecido una visión del conocimiento en su totalidad, puede cumplir nuevamente esta función si los filósofos están dispuestos a adoptar (...) una expresión des-disciplinaria de la filosofía. (shrink)

Uno de los principales filosofos de nuestro tiempo, Robert Nozick, continua en este libro la tradicion socratica de investigacion. Este volumen ilustra la originalidad, fuerza y alcance de su obra, a la vez que demuestra su sello personal al combinar un extraordinario rigor analitico con un inteligente juego intelectual. A traves de ensayos y ficciones filosoficas, el libro abarca desde Socrates hasta Quine. Algunos ensayos ofrecen metodos clasicos para apoyar nuevas preguntas en torno a la eleccion. Otros, nuevas aproximaciones (...) a conocidos puzzles intelectuales. Estos escritos dan testimonio tanto de la oportunidad como de la inoportunidad del pensamiento del autor; pero sobre todo demuestran como la filosofia puede ser una forma de vida. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:482 HISTORY OF PHILOSOPHY disorder was reLigious men's tendency to find in the Scriptures and their consciences justifications for rebelling against their sovereign. The last half of Leviathan is designed to refute these claims in detail, and this refutation is not merely tacked onto the first parts but is a logical extension of them. The argument for escaping the state of nature is that only through obedience to a (...) common power can man escape the likelihood of an early death. Once that common power is established, and so long as it can carry out its protective function, obedience to it is obligatory. When a man enters civil society, the only right he retains is to defend himself against physical death, and consequently, the only time he is entitled to disobey the sovereign is when the sovereign directly threatens him. Thus excuses for rebellion are reduced to an absolute minimum. In McNeiily's formalization however, the concept of a man's death must be replaced by the formal concept of the frustration of all one's desires. And so "whatevvr [a man] regards as the complete frustration of all his desires... he will be entitled to resist, even if such resistance puts him at war with others, including lawful authority" (p. 193). Now the incredible range of things men have believed essential to avoiding the frustration of all their desires is amply testified to in the history of religious warfare. And clearly, under this formalized interpretation, men would be entitled to rebel over the form of baptism, church government, ministerial costume, prayer, or anything else if they are convinced it is essential to their salvation. It takes little knowledge of history to see that Hobbes's espousing of a theory with such consequences has a low degree of probability indeed. Hobbes complains in Leviathan of Scriptural exegetes who "by casting atoms of Scripture, as dust before men's eyes, make everything more obscure than it is." Rather, he claims, it is "not bare words, but the scope of the writer, that giveth the true light by which any writing is to be interpreted; and they that insist upon single texts, without considering the main design, can derive nothing from them clearly'" (E. W., III, 602). This last would be too harsh to apply to McNeiity's work generally, for his "atoms" are for the most part of considerable worth in themselves. But with regard to our understanding of Hobbes's Leviathan he raises a lot of dust. PAUL J. JOHNSON CalifornM State College, San Bernardino The Enlightenment: An Interpretation. By Peter Gay. VoL I, The Rise ol Modern Paganism. (New York: Alfred A. Knopf, 1966. Pp. xviii+SSS+xv); VoL II, The Science ot Freedom. (New York: Alfred A. Knopf, 1969. Pp. xx+70S+xviii) Le grand int~rSt port~ aux ~tudcs du xvm* si~cle au cours des deux derni~res d6cades et la remise en question des principes critiques encore en vigueur it y a une dizaine d'ann~,s ont fray~ la voie h de nouveaux efforts de synth~se dent la derni~re en date, et non la moins int~ressante, est celle de Peter Gay. Ses deux substantiels volumes sent destines ~ servir de guides ~ une nouvelle g~n~ration d'~tudiants et de chercheurs, ne ffit-ce que pour la bibliographie tr~s d6taill~e et accompagn~ d'obserrations personneUes qui forme un supplement tr~s pr6cieux ~ la Bibliographie de D. C. Cabeen de 1951 et de 1968. Lo travail de Peter Gay inspire confianc~ par BOOK REVIEWS 483 Fampleur des lectures auxquelles il s'est astreint et. (shrink)

C. Wright Mills. Letters and Autobiographical Writings. Edited by Kathryn Mills and Pamela Mills. Introduction by Dan Wakefield. xxviii 378 pp., illus., apps., bibl., index. Berkeley/Los Angeles/London: University of California Press,2000. $34.95.

Resumen: El discurso de la economía ha transitado por una tensión entre pertenecer a una Ciencia Social y presentar rasgos prototípicos de una Ciencia Básica. Ahora bien, evidenciar esta hibridez desafía a los investigadores del lenguaje, sobre todo si estos textos son parte de la formación de un economista. Particularmente, el Informe de Política Monetaria no ha sido estudiado desde el punto de vista lingüístico, por lo que se busca observar, en un corpus de 45 textos, si el género IPOM (...) evidencia dicha tensión discursiva de la disciplina. Para lograr ese objetivo, se ha optado por una metodología basada en dos dimensiones: Contexto de Producción y Organización Retórico-Funcional. Tras el análisis, los hallazgos del corpus IPOM-2013 integradamente muestran que el género IPOM efectivamente evidencia dicha tensión con rasgos más características de la CB como es el uso de recursos matemáticos y, por otro lado, rasgos de la CS, asociados a la modalización del discurso en su macromovida central.: The discourse of economy has gone by a constant tension between belonging to a Social Science and present prototypical features of a Basic Science. However, evidence this hybridity poses a challenge for researchers of language, especially if these texts are part of the training of an economist. In particular, the Monetary Policy Report has not been studied from the linguistic point of view. In this context, this research search to answer the question whether the gender IPOM evidences such discursive tension of the discipline. To achieve this objective, it has opted for a methodology based on 2 dimensions: Production Context and Rhetorical-Functional Organization. After the analysis, the findings Integrally shows that the IPOM genre effectively demonstrates this tension with features more characteristic of the BS such as the use of mathematical resources and, on the other hand, SC traits, mainly associated to the modalization of the discourse in its central macromove. (shrink)

Adequate treatment of pain is essential to alleviate suffering, yet studies show that patients with terminal or serious illness receive inadequate pain relief. In the case of terminally ill patients, adequate palliation of pain may be likely to reduce requests for physician-assisted suicide. This issue of the journal addresses barriers to effective pain relief and suggests how treatment of pain can be improved. The symposium features the Pain Relief Act, which is designed to provide practitioners who prescribe controlled substances for (...) pain with protection from inappropriate legal sanctions. The Act is the product of the Project on Legal Constraints on Access to Effective Pain Relief, whose principal investigators were Nancy Neveloff Dubler, LL.B., Sandra H. Johnson, J.D., LL.M., Robert J. Levine, M.D., and Benjamin W. Moulton, J.D., M.P.H.The Project was supported by the Mayday Fund and the Emily Davie and Joseph S. Kornfeld Foundation. (shrink)

Adequate treatment of pain is essential to alleviate suffering, yet studies show that patients with terminal or serious illness receive inadequate pain relief. In the case of terminally ill patients, adequate palliation of pain may be likely to reduce requests for physician-assisted suicide. This issue of the journal addresses barriers to effective pain relief and suggests how treatment of pain can be improved. The symposium features the Pain Relief Act, which is designed to provide practitioners who prescribe controlled substances for (...) pain with protection from inappropriate legal sanctions. The Act is the product of the Project on Legal Constraints on Access to Effective Pain Relief, whose principal investigators were Nancy Neveloff Dubler, LL.B., Sandra H. Johnson, J.D., LL.M., Robert J. Levine, M.D., and Benjamin W. Moulton, J.D., M.P.H.The Project was supported by the Mayday Fund and the Emily Davie and Joseph S. Kornfeld Foundation. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Philosophy and Literature 27.1 (2003) 80-97 [Access article in PDF] Literary Truth as Dreamlike Expression in Foucault's and Borges's "Chinese Encyclopedia" Robert Wicks ALTHOUGH THE TOPIC REMAINS MOSTLY unexplored, Michel Foucault had an aesthetic and intellectual attraction towards writers and artists in the Spanish-speaking tradition. For example, at the conclusion of his Histoire de la folie (Madness and Civilization, 1961)—a book which brought him extensive intellectual recognition in (...) France—Foucault drew his readers' attention to José de Goya y Lucientes's (1746-1828) well-known etching, El Sueño de la Razón Produce Monstruos (The Sleep of Reason Brings Forth Monsters, Plate 43 of Los Caprichos, 1797). In Foucault's estimation, by revealing a "night which is doubtless that of classical unreason," Goya's work represented a socially removed condition within which people encounter "what is most solitary" and experience what is "deepest" within themselves. With his reference to Goya's imagery, Foucault illustrated a major theme of his history of madness, namely, how people referred to as "mentally ill" experienced a gradual, physical exclusion from participation in public society, and how they were eventually isolated in a more frightening way: within their physical confinement, they were subject to techniques of psychological and spiritual alienation that reduced them to a condition of utter solitude.In a comparable, if not more central manner, Foucault used as thematic motifs for the preface, first and second chapters of a book for which he is widely known, Les Mots et les choses (The Order of Things, 1966), the work of three major writers and artists from the Spanish-speaking world: Jorges Luis Borges (1899-1986), Diego Velázquez (1599-1660), and Miguel de Cervantes (1547-1616). Among these references, the most popular is probably Foucault's discussion of [End Page 80] Velázquez's Las Meninas—a painting which captured Foucault's interest as a perfect exemplar of its time period—and which inspired him to devote the entire first chapter of his book to decoding the mechanics of its perspectival arrangement. And within the community of those who read, write and discuss the interrelationship between Foucault's thought, literary theory and the contemporary emphasis upon the multivocal quality of textual meaning, Foucault's citation of an excerpt from a short story by Borges—the subject of this essay—is also familiar. Foucault introduced his 1966 book, The Order of Things, with the following words: This book first arose out of a passage in Borges, out of the laughter that shattered, as I read the passage, all the familiar landmarks of my thought—our thought, the thought that bears the stamp of our age and our geography—breaking up all the ordered surfaces and all the planes with which we are accustomed to tame the wild profusion of existing things, and continuing long afterwards to disturb and threaten with collapse our age-old distinction between the Same and the Other. This passage quotes a "certain Chinese encyclopedia" in which it is written that "animals are divided into: (a) belonging to the Emperor, (b) embalmed, (c) tame, (d) suckling pigs, (e) sirens, (f) fabulous, (g) stray dogs, (h) included in the present classification, (i) frenzied, (j) innumerable, (k) drawn with a very fine camelhair brush, (l) et cetera, (m) having just broken the water pitcher, (n) that from a long way off look like flies." In the wonderment of this taxonomy, the thing we apprehend in one great leap, the thing that, by means of the fable, is demonstrated as the exotic charm of another system of thought, is the limitation of our own, the stark impossibility of thinking that. 1The short story from which Foucault extracted the above, quasi-cubistic, excerpt was published in Borges's 1952 collection, Otras Inquisiciones (Other Inquisitions), and is entitled, "The Analytical Language of John Wilkins." Although this story's entirety is rarely surveyed in discussions of Foucault, appreciating its broader contents helps illuminate why Foucault began The Order of Things with this entertaining and bizarre segment. Borges's original... (shrink)

Este estudio de relaciones médico-paciente en Mexico involucró entrevistas realizadas a 1700 pacientes inmediatamente de.\pués de salir de su consulta clínica. Se llevó a cabo entre los años 2004-05 en León, More ha, Guanajuato y en Charleston, West Virginia, USA. Los propósitos fueron: 1) establecer un base de datos como punto de referencia para investigaciones futuras en instituciones del cuidado de la salud con referencia a la comunicación médico-paciente, a la satisfacción de los pacientes y al consentimiento infórmado y, 2) (...) hacer una comparación entre las relaciones medico-paciente en Mexico y los Estados Unidos de America. Hicimos varias conclusiones sobre la comunicación médico-paciente, participación del paciente en decisiones con respecto a su cuidado de salud y el ambiente social de la consulta médica. Ofi-ecemos los datos y los cuestionarios completos por internet a cualquier investigador interesado para estudios futuros de acuerdo con sus propios intereses. Además, encontramos que no huho ninguna diferencia importante en las relaciones médico-pacientes con respecto al consentimiento infórmado y la satisfáccián del paciente entre México y los EEUU. (shrink)

China es el mayor desafío económico de Europa. La aspiración de China por el dominio geopolítico, económico y tecnológico está tensionando gravemente sus relaciones con Europa, que se encuentran en una clara trayectoria descendente. Las posiciones se han endurecido por ambas partes, con China volviéndose económicamente hacia adentro y la Unión Europea etiquetando a China como un competidor total, con limitadas áreas para el compromiso. El enfoque de China es a largo plazo y estratégico, explotando las divisiones internas de la (...) UE y la débil cooperación transatlántica con Estados Unidos. A China le gustaría tener acceso a tecnologías avanzadas con posibles aplicaciones militares, y ha adquirido puertos europeos y otras infraestructuras estratégicas. A través de la Iniciativa de la Franja y la Ruta, se ha convertido en el mayor acreedor bilateral del mundo. En último término, China busca revisar la arquitectura económica internacional y “reescribir las reglas del juego”. La respuesta de Europa no ha estado bien coordinada, ha sido a corto plazo y fragmentaria, lo que refleja las divisiones internas en la Unión. Para responder eficazmente al desafío de China, Europa necesita superar los intereses nacionales, cooperar con sus aliados y actuar más estratégicamente. (shrink)