OBJECTIVE: Pilot study to characterize treatment differences between patients treated in clinical trials and those treated in a clinical setting. Previous studies have shown higher survival rates for participants in trials of cancer therapy. This difference is observed even after rates are adjusted for important covariates such as age and stage of disease. DESIGN: Retrospective chart review. SETTING: Oncology outpatient department in a tertiary care hospital. PATIENTS: Ninety women 18 to 70 years of age with early-stage breast cancer who were (...) diagnosed in 1990. Fifty-one of the women were treated through clinical trials and 39 were treated outside of clinical trials. OUTCOME MEASURES: Number of blood tests, telephone calls, clinic visits and imaging procedures as well as intensity of chemotherapy and use of radiation therapy. The age of the patient and the stage of disease were important covariates. RESULTS: After the analysis was controlled for patient age and stage of disease, patients treated through a clinical trial were more likely to receive standard-dose chemotherapy (p = 0.020, 95% confidence interval 1.20 to 200.73) and more frequent blood tests (p < 0.001, 95% confidence interval 1.02 to 1.13) than other patients treated in the clinic. CONCLUSIONS: Our results provide a plausible mechanism for the observed survival advantage for participants in clinical trials in oncology. Further study is called for. If these results are confirmed, they have important implications for informed consent to participate in clinical trials and for clinical practice. (shrink)

The organizers of the 1992 Highlands Institute seminar were kind enough to invite me to comment as a neo-pragmatist on John E. Smith's keynote paper "Experience, God, and Classical American Philosophy." It is my pleasure to do so. I read portions of both GOD AND EXPERIENCE and THE ANALOGY OF EXPERIENCE when they were published. I was impressed then, and continue to be impressed, with Professor Smith's intellectually responsible and powerful defense of Christianity, carried out, as it was, in a (...) philosophical environment where that was not the most popular thing to do. More recently, in preparation for this event, I have profited from reading THE SPIRIT OF AMERICAN PHILOSOPHY, particularly the chapters on James and Dewey. And, I can only second his presidential call in "The New Need for a Recovery of Philosophy" for a live-and-let-live attitude amongst the cacophonous multitude of those of us who call ourselves "philosophers.". (shrink)

William Dean is a tireless proponent of a public role for religion in American society, most recently in his American Academy of Religion award winning book The Religious Critic in American Culture . He writes there about the importance of, and need for, both a common American spiritual culture and public intellectuals who would understand, criticize, and innovatively rework that shared American religion. Dean represents a metaphysical strand of American pragmatism. His thought is rooted in William James’s radical empiricism, (...) Bernard Meland’s and Bernard Loomer’s empirical theology, and Alfred North Whitehead’s process metaphysics. He takes seriously what I will call the problem of cosmic estrangement. The American public religion that he advocates, among other things, is supposed to resolve that problem. Its theoretical core is Dean’s version of Whiteheadian panpsychism, which he calls ontological conventionalism. (shrink)

Pragmatism is first and foremost an intellectual self-image. It is a unique way of understanding the mental abilities that distinguish we humans from other living things on earth. The pragmatist description of our mind and its relationship to the rest of the world is a relatively new one. It has its roots in the late nineteenth and early twentieth century work of Charles Sanders Peirce, William James, and John Dewey. These philosophers, influenced by Darwinian biology among other things, redefined (...) the human mind. (shrink)

We Americans put a lot of stock in ingenuity. We admire people who come up with better mousetraps or with better ways to predict economic cycles. William James, in his early essay "Great Men and Their Environment," was the first American pragmatist to suggest that there are interesting analogies between the roles that ingenious people play in social change and bearers of genetic variations play in biological evolution.(1) He proposed that the categories in terms of which we conduct various (...) cultural activities start as idiosyncratic "brainstorms" in the heads of individual human beings, much as Darwin theorized that species start as genetic variations in ancestral organisms. When these mental variations occur in a suitable environment, they may end as new forms of science, morality, art, or religion. Such new ideas enable their bearers to cope with the world differently, and perhaps more profitably, than their ancestors did before them. Social progress when it occurs is a function of the meliorative power of this fortuitous human creativity, not of anything preprogrammed with its own logic or method. (shrink)

Sheila Davaney’s Pragmatic Historicism provides yet another opportunity for us to discuss disagreements between two kinds of pragmatism. One, which I espouse, is a non-metaphysical pragmatism. It is rooted in James’s and Dewey’s appropriation of Darwinian biology for philosophical purposes and, more recently, Donald Davidson’s philosophy of language. Richard Rorty is its most influential contemporary spokesman. The other is a metaphysical pragmatism. It is rooted in James’s radical empiricism and Whitehead’s process philosophy. In the Highlands Institute, William Dean (...) and now Davaney, among others, advocate versions of metaphysical pragmatism. (shrink)

Richard Rorty is famous, maybe even infamous, for his philosophical nonchalance. His groundbreaking work not only rejects all theories of truth but also dismisses modern epistemology and its preoccupation with knowledge and representation. At the same time, the celebrated pragmatist believed there could be no universally valid answers to moral questions, which led him to a complex view of religion rarely expressed in his writings. In this posthumous publication, Rorty, a strict secularist, finds in the pragmatic thought of John Dewey, (...) John Stuart Mill, William James, and George Santayana, among others, a political imagination shared by religious traditions. His intent is not to promote belief over nonbelief or to blur the distinction between religious and public domains. Rorty seeks only to locate patterns of similarity and difference so an ethics of decency and a politics of solidarity can rise. He particularly responds to Pope Benedict XVI and his campaign against the relativist vision. Whether holding theologians, metaphysicians, or political ideologues to account, Rorty remains steadfast in his opposition to absolute uniformity and its exploitation of political strength. (shrink)

Misophonia is a condition characterized by defensive motivational system emotional responding to repetitive and personally relevant sounds. Preliminary research suggests misophonia may be associated with a range of psychiatric disorders, including personality disorders. However, very little research has used clinician-rated psychometrically validated diagnostic interviews when assessing the relationship between misophonia and psychopathology. The purpose of this study was to extend the early research in this area by examining the relationship between symptoms of misophonia and psychiatric diagnoses in a sample of (...) community adults, using semi-structured diagnostic interviews. Results indicated higher misophonia symptoms were associated with more clinician-rated symptoms of personality disorders, but not other disorders. Anxiety partially mediated the relationship between personality disorder symptoms and misophonia. These results suggest misophonia may be associated with a range of psychiatric symptoms and highlight the role of anxiety in this poorly understood condition. (shrink)

Former Google advertising strategist, now Oxford-trained philosopher James Williams launches a plea to society and to the tech industry to help ensure that the technology we all carry with us every day does not distract us from pursuing our true goals in life. As information becomes ever more plentiful, the resource that is becoming more scarce is our attention. In this 'attention economy', we need to recognise the fundamental impacts of our new information environment on our lives in order (...) to take back control. Drawing on insights ranging from Diogenes to contemporary tech leaders, Williams's thoughtful and impassioned analysis is sure to provoke discussion and debate. Williams is the inaugural winner of the Nine Dots Prize, a new Prize for creative thinking that tackles contemporary social issues. This title is also available as Open Access. (shrink)

This is the first critical study of The Logic of Sense, Gilles Deleuze's most important work on language and ethics, as well as the main source of his vital philosophy of the event.James Williams explains the originality of Deleuze's work with careful definitions of all his innovative terms and a detailed description of the complex structure he constructs. This reading makes connections to his ground-breaking work on literature, to his critical but also progressive relation to the sciences, and to (...) his controversial denial of the priority of standard logics, human values and 'meaning' in thinking.This book will open new debates and develop current ones around Deleuze's work in philosophy, politics, literature, linguistics, cultural studies and sociology. (shrink)

Since its inception some fifty years ago, cognitive science has seen a number of sea changes. Perhaps the best known is the development of connectionist models of cognition as an alternative to classical, symbol-based approaches. A more recent - and increasingly influential - trend is that of dynamical-systems-based, ecologically oriented models of the mind. Researchers suggest that a full understanding of the mind will require systematic study of the dynamics of interaction between mind, body, and world. Some argue that this (...) new orientation calls for a revolutionary new metaphysics of mind, according to which mental states and processes, and even persons, literally extend into the environment. This book is a guide to this movement in cognitive science. Each chapter tackles either a specific area of empirical research or specific sector of the conceptual foundation underlying this research. (shrink)

Does the ability to know one's own mind depend on the ability to know the minds of others? According to the 'theory theory' of first-person mentalizing, the answer is yes. Recent alternative accounts of this ability, such as the 'monitoring theory', suggest otherwise. Focusing on the issue of introspective access to propositional attitudes , I argue that a better account of first-person mentalizing can be devised by combining these two theories. After sketching a hybrid account, I show how it can (...) do justice to competing intuitions about the nature of introspective self-awareness. I close by drawing some methodological morals about the study of mentalizing and the role of introspective evidence in cognitive science. (shrink)

Why is American punishment so cruel? While in continental Europe great efforts are made to guarantee that prisoners are treated humanely, in America sentences have gotten longer and rehabilitation programs have fallen by the wayside. Western Europe attempts to prepare its criminals for life after prison, whereas many American prisons today leave their inhabitants reduced and debased. In the last quarter of a century, Europe has worked to ensure that the baser human inclination toward vengeance is not reflected by state (...) policy, yet America has shown a systemic drive toward ever increasing levels of harshness in its criminal policies. Why is America so short on mercy? In this deeply researched, comparative work, James Q. Whitman reaches back to the 17th and 18th centuries to trace how and why American and European practices came to diverge. Eschewing the usual historical imprisonment narratives, Whitman focuses instead on intriguing differences in the development of punishment in the age of Western democracy. European traditions of social hierarchy and state power, so consciously rejected by the American colonies, nevertheless supported a more merciful and dignified treatment of offenders. The hierarchical class system on the continent kept alive a tradition of less-degrading "high-status" punishments that eventually became applied across the board in Europe. The distinctly American, draconian regime, on the other hand, grows, Whitman argues, out of America's longstanding distrust of state power and its peculiar, broad-brush sense of egalitarianism. Low-status punishments were evenly meted out to all offenders, regardless of class or standing. America's unrelentingly harsh treatment of trangressors--this "equal opportunity degradation"-- is, in a very real sense, the dark side of the nation's much vaunted individualism. A sobering look at the growing rift between the United States and Europe, Harsh Justice exposes the deep cultural roots of America's degrading punishment practices. (shrink)

Does the ability to know one's own mind depend on the ability to know the minds of others? According to the 'theory theory' of first-person mentalizing, the answer is yes. Recent alternative accounts of this ability, such as the 'monitoring theory', suggest otherwise. Focusing on the issue of introspective access to propositional attitudes, I argue that a better account of first-person mentalizing can be devised by combining these two theories. After sketching a hybrid account, I show how it can do (...) justice to competing intuitions about the nature of introspective self-awareness. I close by drawing some methodological morals about the study of mentalizing and the role of introspective evidence in cognitive science. (shrink)

The Epicurean philosophical system has enjoyed much recent scrutiny, but the question of its philosophical ancestry remains largely neglected. It has often been thought that Epicurus owed only his physical theory of atomism to the fifth-century BC philosopher Democritus, but this study finds that there is much in his ethical thought which can be traced to Democritus. It also finds important influences on Epicurus in Democritus' fourth-century followers such as Anaxarchus and Pyrrho, and in Epicurus' disagreements with his own Democritean (...) teacher Nausiphanes. The result is not only a fascinating reconstruction of a lost tradition, but also an important contribution to the philosophical interpretation of Epicureanism, bearing especially on its ideal of tranquillity and on the relation of ethics to physics. (shrink)

The infant mortality rate in Liberia is 50 times higher than it is in Sweden, whilst a child born in Japan has a life expectancy at birth of more than double that of one born in Zambia. 1 And within countries, we see differences which are nearly as great. For example, if you were in the USA and travelled the short journey from the poorer parts of Washington to Montgomery County Maryland, you would find that ‘for each mile travelled life (...) expectancy rises about a year and a half. There is a twenty-year gap between poor blacks at one end of the journey and rich whites at the other’. (Marmot, 2004, p.2). There are two types of questions which it is important to ask about inequalities in health such as these. The first are social scientific questions about the extent of inequalities in health and the factors which are causally responsible for these inequalities. Examples of social scientific questions to ask might be: how do infant mortality rates in the UK differ according to social class? What is the difference in life expectancy between Japanese who emigrate to the US and those who remain in Japan? Why do civil servants in higher ranked jobs tend to live longer than civil servants in lower ranked jobs? The second type are normative questions about the reasons we have to care about inequalities in health. Important normative questions to answer are: which inequalities in health should we care about (all inequalities or merely some of them)? When is an inequality in health unjust? How should we weigh our concern for equality in health against other factors such as maximising the.. (shrink)

A revised, expanded and fully up-to-date critical introduction to Deleuze's most important work of philosophyBy critically analysing Deleuze's methods, principles and arguments, James Williams helps readers to engage with the revolutionary core of Deleuze's philosophy and take up positions for or against its most innovative and controversial ideas.

This paper examines the problem of ontotheology as it was defined by Martin Heidegger, and how it has subsequently been approached by those philosophers and theologians who have followed in his wake. It argues that Heidegger’s initial analysis of the onto‐theological condition was mistaken by its presumption of a radical divide between philosophy and theology. Furthermore, many of the key thinkers who have followed after Heidegger have merely reinscribed this supposed divide between thought and faith, rather than genuinely questioning the (...) terms Heidegger thought self‐evident. The result, even among some of the most radical and influential contemporary thinkers such as Emmanuel Levinas, John Caputo, and Jean‐Luc Marion, has been a contemporary philosophy deprived of questions of faith and a theology unaccountable to its place in the world. In response to this shortcoming of contemporary philosophical and theological thought, Jacques Derrida has approached the problem of ontotheology from the dual perspective of both thought and faith, and thereby, has provided a new path of thought beyond the problem of ontotheology and towards a renewed appreciation for the possibilities for a genuine philosophical theology. (shrink)

Current research in moral development suggests that there are two distinct modes of moral reasoning, one based on a morality of justice, the other based on a morality of care. The research presented here examines the kinds of moral reasoning used by managers in work-related conflicts. Twenty men and twenty women were randomly selected from the population of first level managers in a Fortune 100 industrial corporation. In open-ended interviews each participant was asked to describe a situation of moral conflict (...) in her or his work life. The results indicated a clearly preferred mode of moral reasoning among the participants who described moral conflicts. Nearly all of these predominated with a justice orientation. These findings suggest that a correlation between gender and preferred mode may be context specific. (shrink)

One of the great American pragmatic philosophers alongside Peirce and Dewey, William James (1842–1910) delivered these eight lectures in Boston and New York in the winter of 1906–7. Though he credits Peirce with coining the term 'pragmatism', James highlights in his subtitle that this 'new name' describes a philosophical temperament as old as Socrates. The pragmatic approach, he says, takes a middle way between rationalism's airy principles and empiricism's hard facts. James' pragmatism is both a method of (...) interpreting ideas by their practical consequences and an epistemology which identifies truths according to their useful outcomes. Furnished with many examples, the lectures illustrate pragmatism's response to classic problems such as the question of free will versus determinism. Published in 1907, this work further develops James's approach to religion and morality, introduced in The Will to Believe (1897) and The Varieties of Religious Experience (1902), both reissued in this series. (shrink)

Patients -- Clients -- Welfare assessment -- Clinical choices -- Achieving animal welfare goals -- Beyond the clinic.

I. Neville and Moyle Compared The lives of Neville and Moyle span the century in which republicanism of the kind proposed by English ...

Within stakeholder literature, much attention has been given to which stakeholders "really count." This article strives to explain why organizational theorists should abandon the pursuit of "Who and What Really Counts" to challenge the assumption of a managerial perspective that defines stakeholder legitimacy. Reflecting on the paucity of employee rights and protections in marginalized work environments, I argue that as organizational researchers, we must recognize and take responsibility for the impact of our research models and visions. By confronting and rethinking (...) the foundational assumptions of stakeholder theory, business and society scholars can identify and pursue research questions that more effectively address contemporary social challenges. (shrink)

When we talk about intellectual property, it is often implicitly assumed that we are talking about private intellectual property. However, private property and the idea of private ownership do not exhaust the possibilities for accounts of ownership and of property. There are other ways that ownership can operate, such as common property. A resource is common property if its use is ‘governed by rules whose point is to make them available for use by all or any members of the society.’.

This response to Dobson and White’s call for a feminine firm argues that such a concept is based on amisinterpretation of Gilligan’s research. Moreover, virtue ethics and feminine ethics do not share a common approach to nurturing relationships or the moral orientation of care. Acknowledging the worthwhile goals of Dobson and White’s endeavor, the feminist firm is presented as offering greater potential to achieve these goals.

This is the first modern, annotated and scholarly edition of Jean-Baptiste Du Bos’ _Critical Reflections on Poetry and Painting_, one of the seminal works of modern aesthetics in any language.

Pierre Bourdieu is a colossus of postwar sociology. He is the author of over 30 books and more than 350 articles. He is ranked second only to Michel Foucault in the Social Science Citation Index. His work covers many fields - the sociology of culture, research methods, higher education, social theor.

This paper presents a theory of the emergence of ethical relatedness, which is developed through a synthetic reading of the developmental theories of Melanie Klein and Maurice Merleau-Ponty. Klein's theory of the paranoid-schizoid and depressive positions are found to roughly parallel Merleau-Ponty's distinction between the "lived" and the "symbolic." With the additional contributions of Thomas Ogden and Martin C. Dillon, the theories of Klein and Merleau-Ponty are refined to accommodate the insights of each developmental perspective. Implications of the paper's analysis (...) include: Opportunities to clarify key concepts in object relations theory, including projective identification; insight into the development of self-conscious emotions such as shame, guilt, embarrassment and gratitude; the articulation of a phenomenologically oriented object relations perspective which allows for human agency and therefore genuine altruism and compassion; and, finally, a validation of previous assertions that theory cannot and should not be meaningfully distinguished from ethics. 2012 APA, all rights reserved). (shrink)

Building on organizational justice research, we extended the study of classroom justice to management education. In the first study, we identified the criteria that business students use to define distributive, procedural, and interactional fairness. In a second study, we found that management students? perceptions of both procedural and interactional fairness were significant and unique predictors of their evaluations of instructional effectiveness. However, procedural justice was the only significant predictor of overall evaluations of the course. Results of this study will aid (...) management educators in implementing procedures and treatment that students perceive as fair and also to serve as ethical role models for managers of the future. (shrink)

Noted psychologist and philosopher develops his own brand of pragmatism, based on theories of C. S. Peirce. Emphasis on "radical empiricism," versus the transcendental and rationalist tradition. One of the most important books in American philosophy. Note.

Amie Thomasson’s work provides numerous ways to rethink and improve our approach to metaphysics. This chapter is my attempt to begin to sketch why I still think the easy approach leaves room for substantive metaphysical work, and why I do not think that metaphysics need rely on any ‘epistemically metaphysical’ knowledge. After distinguishing two possible forms of deflationism, I argue that the easy ontologist needs to accept (implicitly or explicitly) that there are worldly constraints on what sorts of entities could (...) exist, and could co-exist. I argue this leaves room for a substantive role for metaphysics if (following the work of E.J. Lowe) we take metaphysics to be concerned with the possible ways that reality could be. I explain how this conception does not need to appeal to any ‘epistemically metaphysical’ knowledge, and need only make use of conceptual and/or empirical means to arrive at views on what could exist (and co-exist). Thus, the answer I propose to the question posed in the title, at least in my view, is no-one. Or, at least, no-one should be afraid of conceptual analysis. Not even metaphysicians. (shrink)

Linguistic anthropologists have studied emotion in societies around the world for several decades. This article defines the discipline, introduces its general relevance to emotion theory, then presents five of the most important contributions linguistic anthropology has made to the study of emotion.

A number of philosophers with a metaphysical orientation have criticized Making Things Happen for its failure to provide an account of the metaphysical foundations or grounds or truth-makers for causal and explanatory claims. This dialog attempts to respond to these objections and to raise some general concerns about some of the rhetoric and argumentative strategies employed in contemporary analytic metaphysics. It also explores some issues having to do with the relationship between methodology, understood as a core concern of philosophy of (...) science, and analytic metaphysics. (shrink)

A pioneer in early studies of the human mind and founder of that peculiarly American philosophy called Pragmatism, William James remains America's most widely read philosopher. Generations of students have been drawn to his lucid presentations of philosophical problems. His works, now being made available for the first time in a definitive edition, have a permanent place in American letters and a continuing influence in philosophy and psychology. The essays gathered in the posthumously published Essays in Radical Empiricism formulate (...) ideas that had brewed in James's mind for thirty years as he sought a way out of the philosophical dilemmas generated by the new psychology of the late nineteenth century. They constitute the explanatory core of his doctrine of radical empiricism, a doctrine that charts his course between the absolute idealism he could not accept and, at the other extreme, the law of associationism, which reduces knowledge to sheer contiguity of ideas. In his introduction John J. McDermott describes the historical background and the genesis of James's theory and considers the objections raised by its opponents. (shrink)

In the Eighth Olympian, for Alcimedon of Aegina, Pindar recounts a story that, according to a notice in the scholia, is not found in earlier Greek literature. Aeacus was summoned from Aegina to Troy by Apollo and Poseidon to help in the construction of the city's fortifications. Smoke, says the poet, would one day rise from the very battlements Aeacus built. The wall newly completed, a portent appeared: three snakes tried to scale the ramparts but two fell to earth while (...) one succeeded in entering the city. Apollo immediately interpreted this sign: Troy would be taken ‘owing to the work of Aeacus’ hand' and would, moreover, be taken ‘by the first and the fourth generations’. If there is literary invention here, it would seem that Pindar has drawn inspiration from three passages of our Iliad: 7.452–3, Apollo and Poseidon toiled to build a wall for Laomedon; 6.433–4, there was one spot in the wall of Troy that was especially vulnerable; 2.308–29, the seer Calchas declares an omen involving a snake to signify the eventual destruction of Ilium. The general import of the passage is clear enough — descendants of Aeacus play a prominent part in the Trojan war and in the capture of the city. But the details of the portent and of the prophecy have caused much perplexity, for they cannot easily be made to correspond to the history they prefigure. It is the numbers in Pindar's account that are the chief source of confusion. On the model of the omen interpreted by Calchas the three snakes in the Pindaric story might reasonably be expected to represent the lapse of three generations before Aeacus' great-grandson Neoptolemus played his conspicuous part in the final agony of Troy. But this interpretation of the portent forces us to explain away the fact that Troy was also destroyed by Aeacus' son, Telamon, as Pindar repeatedly insists in his Aeginetan odes : if the snakes are taken to represent generations, one of the unsuccessful snakes in fact represents a successful conqueror. This is a disturbing inconcinnity. (shrink)