When discussing the changing sense of reality around 1900 in the cultural arts the lexicon of early modernism reigns supreme. This essay contends that a critical condition for the possibility of many of the turn of the century modernist movements in the arts can be found in exchange of instruments, concepts, and media of representation between the sciences and the arts. One route of interaction came through physiological aesthetics, the attempt to ‘elucidate physiologically the nature of our Aesthetic feelings’ and (...) explain how works of art achieve their effects. Physiological aesthetics provided the terms for new formalist languages of art and criticism, and in some instances suggested optimistic, even utopian, possibilities for art to remake human individuals and societies.Keywords: Physiology; Psychology; Evolution; Aesthetics; Modernism; Art history. (shrink)

Although contemporary sociologists of science have sometimes claimed Max Weber as a methodological precursor, they have not examined Weber's own writings about science. Between 1908 and 1912 Weber published a series of critical studies of the extension of scientific authority into public life. The most notable of these concerned attempts to implement the experimental psychology or psycho-physics laboratory in factories and other real-world settings. Weber's critique centered on the problem of social measurement. He emphasized the discontinuities between the space of (...) the laboratory and that of the factory, showing how several qualitative and historically conditioned differences between the two settings rendered the transfer of instruments and methods between them highly problematic. Weber's critical arguments prepared the ground for his greatest foray into empirical sociology, a survey he directed for the Verein für Sozialpolitik investigating the conditions and attitudes affecting the lives and performance of industrial workers. Using a different measuring instrument — the questionnaire — Weber tried to implement a concept of social measurement which implied a different ontology, drawn not from natural sciences but from the historical sciences. (shrink)

In everyday parlance, "inhibition" suggests repression, tight control, the opposite of freedom. In medicine and psychotherapy the term is commonplace, its definition understood. Relating how inhibition—the word and the concept—became a bridge between society at large and the natural sciences of mind and brain, Smith constructs an engagingly original history of our view of ourselves. Not until the late nineteenth century did the term "inhibition" become common in English, connoting the dependency of reason and of civilization itself on (...) the repression of "the beast within." This usage followed a century of Enlightenment thought about human nature and the nature of the human mind. Smith traces theories of inhibitory control from the moralistic psychologies of the early nineteenth century to the famous twentieth-century schools of Sherrington, Pavlov, and Freud. He finds that the meanings of "inhibition" cross disciplinary boundaries and outline the growth of our belief in the self-regulated person. (shrink)

This fine book tells an important story of how long-standing notions about the body as dominated by spirit-like humors were transformed into scientific descriptions of its solid tissues. Vesalius, Harvey, Descartes, Willis, and Locke all played roles in this transformation, as the cerebral hemispheres and cranial nerves began to take precedence over the role of spirit, passion, and the heart in human thought and behavior. Non of this occurred in a social vacuum, and the book describes the historical context clearly. (...) It also shows how debates over investigative methods and models of body order that first raged over 300 years ago continue to influence biomedicine and the broader culture today. No other book on western mind-body relationships has attempted this. (shrink)

An opinionated history of neuroscience, which argues that--due to the brain's complexity--neuroscientific theories have only captured partial truths, and therefore "neurophilosophy" is unlikely to be achieved.

This volume of essays examines the problem of mind, looking at how the problem has appeared to neuroscientists from classical antiquity through to contemporary times. Beginning with a look at ventricular neuropsychology in antiquity, this book goes on to look at Spinozan ideas on the links between mind and body, Thomas Willis and the foundation of Neurology, Hooke’s mechanical model of the mind and Joseph Priestley’s approach to the mind-body problem. The volume offers a chapter on the 19th century Ottoman (...) perspective on western thinking. Further chapters trace the work of nineteenth century scholars including George Henry Lewes, Herbert Spencer and Emil du Bois-Reymond. The book covers significant work from the twentieth century, including an examination of Alfred North Whitehead and the history of consciousness, and particular attention is given to the development of quantum consciousness. Chapters on slavery and the self and the development of an understanding of Dualism bring this examination up to date on the latest 21st century work in the field. At the heart of this book is the matter of how we define the problem of consciousness itself: has there been any progress in our understanding of the working of mind and brain? This work at the interface between science and the humanities will appeal to experts from across many fields who wish to develop their understanding of the problem of consciousness, including scholars of Neuroscience, Behavioural Science and the History of Science. (shrink)

Biological evolution and technological innovation, while differing in many respects, also share common features. In particular, implementation of a new technology in the market is analogous to the spreading of a new genetic trait in a population. Technological innovation may occur either through the accumulation of quantitative changes, as in the development of the ocean clipper, or it may be initiated by a new combination of features or subsystems, as in the case of steamships. Other examples of the latter type (...) are electric networks that combine the generation, distribution, and use of electricity, and containerized transportation that combines standardized containers, logistics, and ships. Biological evolution proceeds, phenotypically, in many small steps, but at the genetic level novel features may arise not only through the accumulation of many small, common mutational changes, but also when distinct, relatively rare genetic changes are followed by many further mutations. In particular, capabilities of biologically modern man may have been initiated, perhaps some 150 000 years ago, by one or few accidental but distinct combinations of modules and subroutines of gene regulation which are involved in the generation of the neural network in the cerebral cortex. It is even conceivable that it was one primary genetic event that initiated the evolution of biologically modern man, introducing some novel but subtle feature of connectivity into the cerebral cortex which allowed for meta-levels of abstraction and upgraded modes of information processing. This may have set the stage for the evolution of integrated but diverse higher capabilities such as structured language, symbolic thought, strategic thought, and cognition based empathy. (shrink)

English-language translation of a major work by French philosopher Eric Alliez, in which he offers a new perspective on critical problems in modern aesthetics.

Longlisted for the PEN/E.O. Wilson Literary Science Writing Award A leading neuroscientist offers a history of the evolution of the brain from unicellular organisms to the complexity of animals and human beings today Renowned neuroscientist Joseph LeDoux digs into the natural history of life on earth to provide a new perspective on the similarities between us and our ancestors in deep time. This page-turning survey of the whole of terrestrial evolution sheds new light on how nervous systems (...) evolved in animals, how the brain developed, and what it means to be human. In The Deep History of Ourselves, LeDoux argues that the key to understanding human behavior lies in viewing evolution through the prism of the first living organisms. By tracking the chain of the evolutionary timeline he shows how even the earliest single-cell organisms had to solve the same problems we and our cells have to solve each day. Along the way, LeDoux explores our place in nature, how the evolution of nervous systems enhanced the ability of organisms to survive and thrive, and how the emergence of what we humans understand as consciousness made our greatest and most horrendous achievements as a species possible. (shrink)

The essence of who we are depends on our brains. They enable us to think, to feel joy and sorrow, communicate through speech, reflect on the moments of our lives, and to anticipate, plan for, and worry about our imagined futures. Although some of our abilities are comparatively new, key features of our behavior have deep roots that can be traced to the beginning of life. By following the story of behavior, step-by-step, over its roughly four-billion-year trajectory, we come to (...) understand both how similar we are to all organisms that have ever lived, and how different we are from even our closest animal relatives. We care about our differences because they are ours. But differences do not make us superior; they simply make us different. (shrink)

English-language translation of a major work by French philosopher Eric Alliez, in which he offers a new perspective on critical problems in modern aesthetics.

This essay introduces a Focus section on “Neurohistory and History of Science” by distinguishing images of the brain as governor and as transducer: the former treat the brain as the executive control center of the body, the latter as an interface between the organism and reality at large. Most of the consternation expressed in the symposium about the advent of neurohistory derives from the brain-as-governor conception, which is rooted in a “biologistic” understanding of humanity that in (...) recent years has become bound up in various nefarious “neoliberal” political and economic agendas. However, given the sophisticated attitude that neurohistory’s leading champion, Daniel Smail, displays toward evolutionary theory’s potential impact on historical practice, he is perhaps better understood as part of the brain-as-transducer tradition. This tradition, largely suppressed in current representations of neuroscience, has a strong theological provenance, ultimately concerned with our becoming attuned to the divine frequency, not least by extending the powers of the human nervous system through technology. This essay sympathetically explores the implications of this perspective for historical practice. (shrink)

Every year millions of people suffer minor brain injuries, many of which occur in collision sports. While there has been substantial commentary and debate about the nature of this public health crisis, it is clear that the scientific and clinical arguments reflect values preferences and judgments that are often invisible in documents which combine artful language with undue focus paid to sources of uncertainty at the cost of clarity and transparency. This essay gives a brief history of these (...) patterns and proposes a remedy. (shrink)

Princess Diana’s death was a tragedy that provoked mourning across the globe; the death of a homeless person, more often than not, is met with apathy. How can we account for this uneven distribution of emotion? Can it simply be explained by the prevailing scientific understanding? Uncovering a rich tradition beginning with Aristotle, _The Secret History of Emotion_ offers a counterpoint to the way we generally understand emotions today. Through a radical rereading of Aristotle, Seneca, Thomas Hobbes, Sarah Fielding, (...) and Judith Butler, among others, Daniel M. Gross reveals a persistent intellectual current that considers emotions as psychosocial phenomena. In Gross’s historical analysis of emotion, Aristotle and Hobbes’s rhetoric show that our passions do not stem from some inherent, universal nature of men and women, but rather are conditioned by power relations and social hierarchies. He follows up with consideration of how political passions are distributed to some people but not to others using the Roman Stoics as a guide. Hume and contemporary theorists like Judith Butler, meanwhile, explain to us how psyches are shaped by power. To supplement his argument, Gross also provides a history and critique of the dominant modern view of emotions, expressed in Darwinism and neurobiology, in which they are considered organic, personal feelings independent of social circumstances. The result is a convincing work that rescues the study of the passions from science and returns it to the humanities and the art of rhetoric. (shrink)

This review article critically surveys the following literature by placing it under the historiographical banner of ‘the history of the brain and mind sciences’: Fernando Vidal and Francisco Ortega, Being Brains: Making the Cerebral Subject (New York: Fordham University Press, 2017); Katja Guenther, Localization and its Discontents: A Genealogy of Psychoanalysis & the Neuro Disciplines (Chicago: University of Chicago Press, 2015); Stephen Casper and Delia Gavrus (eds), The History of the Brain and Mind Sciences: Technique, Technology, (...) Therapy (Rochester: University of Rochester Press, 2017); Jonna Brenninkmeijer, Neurotechnologies of the Self: Mind, Brain and Subjectivity (London: Palgrave Macmillan, 2016). This framework highlights contemporary attempts to historicize the integrative project of neuroscience and set the correct limits to interdisciplinary collaboration. While attempts to critically engage with the ‘neuro’ rhetoric of contemporary neuroscientists can seem at odds with historians seeking to write the history of neuroscience from the margins, it is argued that together these two projects represent a positive historiographical direction for the history of the neurosciences after the decade of the brain. (shrink)

review of Martensen's book The Brain Takes Shape (CUP).

This review article critically surveys the following literature by placing it under the historiographical banner of ‘the history of the brain and mind sciences’: Fernando Vidal and Francisco Ortega, Being Brains: Making the Cerebral Subject (New York: Fordham University Press, 2017); Katja Guenther, Localization and its Discontents: A Genealogy of Psychoanalysis & the Neuro Disciplines (Chicago: University of Chicago Press, 2015); Stephen Casper and Delia Gavrus (eds), The History of the Brain and Mind Sciences: Technique, Technology, (...) Therapy (Rochester: University of Rochester Press, 2017); Jonna Brenninkmeijer, Neurotechnologies of the Self: Mind, Brain and Subjectivity (London: Palgrave Macmillan, 2016). This framework highlights contemporary attempts to historicize the integrative project of neuroscience and set the correct limits to interdisciplinary collaboration. While attempts to critically engage with the ‘neuro’ rhetoric of contemporary neuroscientists can seem at odds with historians seeking to write the history of neuroscience from the margins, it is argued that together these two projects represent a positive historiographical direction for the history of the neurosciences after the decade of the brain. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:The Secret History of Emotion: From Aristotle's ‘Rhetoric’ to Modern Brain ScienceMichael J. HydeThe Secret History of Emotion: From Aristotle's ‘Rhetoric’ to Modern Brain Science. Daniel M. Gross. Chicago: University of Chicago Press, 2006. Pp. x + 194. $35.00, Hardcover.The twofold goal of this book is clearly stated by its author: "to reconstitute by way of critical intellectual history a deeply nuanced, rhetorical (...) understanding of emotion that prevailed until the triumph of psychophysiology; second, to show by way of literary and philosophical example how this rhetorical perspective helps us read anew the emotional complex of modernity, whether early or late" (8). Gross' appreciation of the function of emotion emphasizes a phenomenological orientation that is inspired by Martin Heidegger's unpublished 1924 lecture course on Aristotle's Rhetoric. Gross recently co-edited with Ansgar Kemmann a book of original essays dedicated to a critical assessment of this lecture course (Gross and Kemmann 2006). In concluding her contribution to the book, the well-known Renaissance scholar Nancy S. Struever maintains that the course "remains, arguably, the best twentieth-century reading of Aristotle's Rhetoric" (Struever 2006: 127). Gross advances this reading with his creative and insightful assessment of his topic.This advance unfolds as Gross, abiding by phenomenology's well-known critique of the matter, takes issue with the reductive psychophysiology of emotion that Descartes first proposed and that informs latter-day sciences of the mind and the brain. Gross turns to the research program of the distinguished cognitive scientist Antonio Damasio as a way of arguing "how brain science of emotion goes awry when it blunders into social fact" (29). The reductionism of science, in other words, misses the forest for the trees. Admitting that Damasio is open to inquiries outside the boundaries of neurobiology, Gross nevertheless takes particular issue with Damasio's model for such a project: Edward O. Wilson's, Consilience: The Unity of Knowledge. Indeed, Wilson never gives rhetoric a nod when he acknowledges the worth of the humanities in his book.This slight, coming from Wilson, Damasio, and other scientists, fuels Gross's enthusiasm for turning to Aristotle's analysis of the pathe in book two of the Rhetoric. With Aristotle's discussion of "anger" in mind, for example, Gross emphasizes how we live in "a contoured world of emotional investments, where some people have significantly more liabilities than others" (3). [End Page 326]The point warrants elaboration: "The contours of our emotional world have been shaped by institutions such as slavery and poverty that simply afford some people greater emotional range than others, as they are shaped by publicity that has nothing to do with the inherent values of each human life and everything to do with technologies of social recognition and blindness" (4). Gross links this Aristotelian based social-psychological insight with such early modern philosophers, psychologists, and cultural critics as Thomas Hobbes, David Hume, William Perfect, and then with such contemporary intellectuals as Judith Butler. Gross' discussion of this linkage enables him to argue a key point in his overall project: the constitutive power of emotions depends not on how the social passions originate in a moral sense equally shared by all, but rather on the "uneven distribution" of these passions in our social and political lives.Gross makes much of how the rhetoric of this uneven distribution is at work in such particular cases as Aristotle's apathetic slave, Seneca's angry tyrant, Hobbes's resentful preacher, Sarah Fielding's humble hero, and Adam Smith's compassionate spectator. Gross's intellectual acumen shines as he weaves together these cases and expands on their implications for developing a rhetorical understanding of emotion. For example, in chapter three ("Virtues of Passivity in the English Civil War"), Gross offers a critical assessment of Michael Walzer's classic The Revolution of the Saints: A Study in the Origins of Radical Politics in order to show how the emotional makeup of passivity, too often "relegated to a diminished femininity" (87), not only informs the virtue of humility, but also helps it serve rhetorically "the most dramatic revolutionary ends" (110). Additional extended case studies emphasize the specific emotions of apathy, pride, pity... (shrink)

The concept of brain death as equivalent to cardiopulmonary death was initially conceived following developments in neuroscience, critical care, and transplant technology. It is now a routine part of medicine in Western countries, including the United States. In contrast, Eastern countries have been reluctant to incorporate brain death into legislation and medical practice. Several countries, most notably China, still lack laws recognizing brain death and national medical standards for making the diagnosis. The perception is that Asians are (...) less likely to approve of brain death or organ transplant from brain dead donors. Cultural and religious traditions have been referenced to explain this apparent difference. In the West, the status of the brain as home to the soul in Enlightenment philosophy, combined with pragmatism and utilitarianism, supports the concept of brain death. In the East, the integration of body with spirit and nature in Buddhist and folk beliefs, along with the Confucian social structure that builds upon interpersonal relationships, argues against brain death. However, it is unclear whether these reasoning strategies are explicitly used when families and medical providers are faced with acknowledging brain death. Their decisions are more likely to involve a prioritization of values and a rationalization of intuitive responses. Why and whether there might be differences between East and West in the acceptance of the brain death concept requires further empirical testing, which would help inform policy-making and facilitate communication between providers and patients from different cultural and ethnic backgrounds. (shrink)

In everyday parlance, "inhibition" suggests repression, tight control, the opposite of freedom. In medicine and psychotherapy the term is commonplace, its definition understood. Relating how inhibition—the word and the concept—became a bridge between society at large and the natural sciences of mind and brain, Smith constructs an engagingly original history of our view of ourselves. Not until the late nineteenth century did the term "inhibition" become common in English, connoting the dependency of reason and of civilization itself on (...) the repression of "the beast within." This usage followed a century of Enlightenment thought about human nature and the nature of the human mind. Smith traces theories of inhibitory control from the moralistic psychologies of the early nineteenth century to the famous twentieth-century schools of Sherrington, Pavlov, and Freud. He finds that the meanings of "inhibition" cross disciplinary boundaries and outline the growth of our belief in the self-regulated person. (shrink)

The human brain has long been misunderstood in its features. It is up to neuroscience to have shown that all its activities are connected, and understand each other only in this relationship between its different instances. To ascend, to merge, to connect are the basis of the organization of our psyche, including in its most elaborate symbolic productions. This is precisely the system highlighted by the Anthropological Structures of the Imaginary by Gilbert Durand, brilliant precursor.

The relationship between brain and mind has been extensively explored through the developments within neuroscience over the last decade. However, the ontological status of mind has remained fairly problematic due to the inability to explain all features of the mind through the brain. This inability has been considered largely due to partial knowledge of the brain. It is claimed that once we gain complete knowledge of the brain, all features of the mind would be explained adequately. (...) However, a challenge to such a position is downward causation: How do we explain the causal power that mental states exert over brain activities? If we agree that downward causation occurs, then to what extent could a sole explanation of brain activities account for our behaviour? (For they would in themselves be conditioned by the mental states which are left unexplained). This dissertation is an attempt to understand relation between brain and mind through the concept of emergence, placed in the context of complex systems approach. This will create a space to account for the causal power of mental states. The complex systems approach says that as the complexity of a system increases, we witness the emergence of novel qualities and after a certain threshold (of complexity), the emergence of a novel structure. When the body (and correspondingly, brain) reaches a certain level of complexity, the mind emerges. The brain is a complex system from which the mind emerges. The brain, consisting of billions of neurons interacting with each other, regulates the body placed in the environment. The interaction of neurons (local interactions involving self-organization) result in dynamical brain signatures (global synergy). Such signatures are correlative to mental states. Mind is the process of a living organism embodying an intentional stance. This object could be the subject itself or another distinct from the subject. With the emergence of mind, the causal powers of brain are conditioned by the mind. Such a conditioning is evident through the causal efficacy of mental states. While the brain is minimal condition for the mind to emerge, the mind in itself is embedded (showcased/explicated/manifested) throughout the body. The mind is a process that belongs to body-as-a-whole with the novel quality of intentionality. A preliminary to understanding this relation is its metaphysical inclination. A large portion of the history of philosophy of mind has advocated a metaphysics of entities where the mind and body have been seen as two entities with distinct essences. However, such attribution of entity-ship does not take into account the processual nature of these existents (that they are essentially dependent on their environment for their existence and sustenance). Thus, the category of processual unity has been introduced which sought to account for existent as emergent wholes that move towards a stable equilibrium through self-organization. By considering existents to be processual unities, we can account for their identity as a whole-in-itself (what has been called organizational closure) and also for their processual nature. The brain is a component of the body which is a complex system and is representative of the body’s stance in the world. The brain, consisting of billions of neurons interacting with each other, regulates the body placed in the environment. The interaction of neurons (local interactions involving self-organization) result in dynamical brain signatures (global synergy). Such signatures are correlative to mental states. These mental states in turn condition the brain patterns, that allows the embodying of mental states. Thus, the three-way process of the representation of body in the world by the brain, the emergence of mental state through dynamic brain patterns and the reciprocal causal power on the brain patterns by the mental states marks embodiment. The relation between brain, body and mind can be outlined as follows: A. There are complex interactions in the brain. These interactions are representative of the body’s stance in the world and are present in form of dynamical brain signatures. B. The dynamical brain signatures lead to emergence of mind as a process. The mental state has causal power which conditions the brain. C. The brain conditioned by causal power of the mind carries out embodiment of the mind throughout the body. In the dissertation, an exposition on relation between brain and mind through complex system approach is followed by a brief on relation between body and mind. The radical embodiment approach adopts the nonlinear dynamic systems theory to understand relation of brain, body and mind. It states a shift from mapping of cognitive states onto Neural Correlates of Consciousness to their mapping through dynamic brain signatures. Every mental state is embedded throughout the body. The dissertation explores the three features of consciousness, intentionality and qualia. These have previously formed a challenge within a dualistic framework and the dissertation intends to show a direction in which they can be accounted for, within the complex systems approach and radical embodiment viewpoint. After a certain threshold of the rate of production of cell assemblies is bypassed, we become conscious of the representation itself. This leads to emergence of phenomenal states. Qualia is the qualitative character of such states, which belong to the body-as-a-whole and for this reason, cannot be reduced to properties of any of the components from which it emerges (the dynamic brain signatures) or in which it is embodied (the body and its individual parts) alone. Intentionality is the novel property of mind of moving towards a certain set of attractors where attractors refer to the states that the system prefers (which would positively contribute to its fitness). The scope of this dissertation is to delineate the relation of brain to the mind and unravel some persistent troubles of philosophy of mind within such delineation. The types of components and their relation within the mind preceded by a thorough study of how the mind is embodied is an area yet to be extensively explored in the coming works. (shrink)

Throughout human history, thoughts, values and behaviors have been colored by language and the prevailing view of the universe. With the advent of Quantum Mechanics, relativity, non-Euclidean geometries, non-Aristotelian logic and General Semantics, the scientific view of the world has changed dramatically from just a few decades ago. Nonetheless, human thinking is still deeply rooted in the cosmology of the middle ages. Quantum Psychology is the book to change your way of perceiving yourself--and the universe for the 21st Century. (...) Some say it's materialistic, others call it scientific and still others insist it's mystical. It is all of these--and none. (shrink)

Embodied human minds operate in and spread across a vast and uneven world of things—artifacts, technologies, and institutions which they have collectively constructed and maintained through cultural and individual history. This chapter seeks to add a historical dimension to the enthusiastically future-oriented study of “natural-born cyborgs” in the philosophy of cognitive science,3 and a cognitive dimension to recent work on material memories and symbol systems in early modern England, bringing humoral psychophysiology together with material culture studies. The aim is (...) to sketch an integrative framework which spans early modern ideas and practices relating to brains, bodies, memory, and objects. Embodiment and environment, I’ll argue, were not (always) merely external influences on feeling, thinking, and remembering, but (in certain circumstances) partly constitutive of these activities. (shrink)

Rationale: Deep brain stimulation (DBS) of the hippocampus is proposed for enhancement of memory impaired by injury or disease. Many pre-clinical DBS paradigms can be addressed in epilepsy patients undergoing intracranial monitoring for seizure localization, since they already have electrodes implanted in brain areas of interest. Even though epilepsy is usually not a memory disorder targeted by DBS, the studies can nevertheless model other memory-impacting disorders, such as Traumatic Brain Injury (TBI). Methods: Human patients undergoing Phase II (...) invasive monitoring for intractable epilepsy were implanted with depth electrodes capable of recording neurophysiological signals. Subjects performed a delayed-match-to-sample (DMS) memory task while hippocampal ensembles from CA1 and CA3 cell layers were recorded to estimate a multi-input, multi-output (MIMO) model of CA3-to-CA1 neural encoding and a memory decoding model (MDM) to decode memory information from CA3 and CA1 neuronal signals. After model estimation, subjects again performed the DMS task while either MIMO-based or MDM-based patterned stimulation was delivered to CA1 electrode sites during the encoding phase of the DMS trials. Each subject was sorted (post hoc) by prior experience of repeated and/or mild-to-moderate brain injury (RMBI), TBI, or no history (control) and scored for percentage successful delayed recognition (DR) recall on stimulated vs. non-stimulated DMS trials. The subject’s medical history was unknown to the experimenters until after individual subject memory retention results were scored. Results: When examined compared to control subjects, both TBI and RMBI subjects showed increased memory retention in response to both MIMO and MDM-based hippocampal stimulation. Furthermore, effects of stimulation were also greater in subjects who were evaluated as having pre-existing mild-to-moderate memory impairment. Conclusion: These results show that hippocampal stimulation for memory facilitation was more beneficial for subjects who had previously suffered a brain injury (other than epilepsy), compared to control (epilepsy) subjects who had not suffered a brain injury. This study demonstrates that the epilepsy/intracranial recording model can be extended to test the ability of DBS to restore memory function in subjects who previously suffered a brain injury other than epilepsy, and support further investigation into the beneficial effect of DBS in TBI patients. (shrink)

Although the term integration is central to the definition of brain death, there is little agreement on what it means. Through a genealogical analysis, this essay argues that there have been two primary ways of understanding integration in regard to organismal wholeness. One stems from neuroscience, focusing on the role of the brain in responding to external stimuli, which was taken up in phenomenological accounts of life. A second, arising out of cybernetics, focuses on the brain’s role (...) in homeostasis. Recent debates over brain death are largely over this cybernetic understanding of integration. However, the phenomenological understanding of organismal wholeness can be seen in arguments by the President’s Council on Bioethics in favor of brain death. This essay argues that the cybernetic understanding of life is problematic and should be discarded. A phenomenological understanding of life can provide a better basis for arguments over definitions of life and death. (shrink)