Results for ' Lipidomic profiling'

999 found
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  1.  9
    Metabolomics meets lipidomics: Assessing the small molecule component of metabolism.Hector Gallart-Ayala, Tony Teav & Julijana Ivanisevic - 2020 - Bioessays 42 (12):2000052.
    Metabolomics, including lipidomics, is emerging as a quantitative biology approach for the assessment of energy flow through metabolism and information flow through metabolic signaling; thus, providing novel insights into metabolism and its regulation, in health, healthy ageing and disease. In this forward‐looking review we provide an overview on the origins of metabolomics, on its role in this postgenomic era of biochemistry and its application to investigate metabolite role and (bio)activity, from model systems to human population studies. We present the challenges (...)
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  2.  25
    Lipids under stress – a lipidomic approach for the study of mood disorders.André Miguel Miranda & Tiago Gil Oliveira - 2015 - Bioessays 37 (11):1226-1235.
    The emerging field of lipidomics has identified lipids as key players in disease physiology. Their physicochemical diversity allows precise control of cell structure and signaling events through modulation of membrane properties and trafficking of proteins. As such, lipids are important regulators of brain function and have been implicated in neurodegenerative and mood disorders. Importantly, environmental chronic stress has been associated with anxiety and depression and its exposure in rodents has been extensively used as a model to study these diseases. With (...)
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  3. Are Emotions Perceptions of Value (and Why this Matters)?Charlie Kurth, Enter Author Name Without Selecting A. Profile: Haley Crosby & Enter Author Name Without Selecting A. Profile: Jack Basse - forthcoming - Philosophical Psychology.
    In Emotions, Values & Agency, Christine Tappolet develops a sophisticated, perceptual theory of emotions and their role in wide range of issues in value theory and epistemology. In this paper, we raise three worries about Tappolet's proposal.
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  4. Robert Torre: Ima li života prije smrti? Iskustvo prvog lica. [REVIEW]Danijela Godinić & Enter Author Name Without Selecting A. Profile: - 2019 - Filozofska Istrazivanja 39:265-268.
  5.  4
    Hypothesis: Clues From Mammalian Hibernation for Treating Patients With Anorexia Nervosa.Barbara Scolnick - 2018 - Frontiers in Psychology 9.
    This hypothesis is that anorexia nervosa is a biologically driven disorder, and mammalian hibernation may offer clues to its pathogenesis. Using this approach, this hypothesis offers suggestions for employing heart rate variability as an early diagnostic test for anorexia nervosa; employing the ketogenic diet for refeeding patients, attending to omega 3:6 ratio of polyunsaturated fatty acids in the refeeding diet; and exploring clinical trials of the endocannabinoid-like agent, palmitoylethanolamde for patients with anorexia nervosa. This hypothesis also explores the role of (...)
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  6.  64
    Profiles of animal consciousness: A species-sensitive, two-tier account to quality and distribution.Leonard Dung & Albert Newen - 2023 - Cognition 235 (C):105409.
    The science of animal consciousness investigates (i) which animal species are conscious (the distribution question) and (ii) how conscious experience differs in detail between species (the quality question). We propose a framework which clearly distinguishes both questions and tackles both of them. This two-tier account distinguishes consciousness along ten dimensions and suggests cognitive capacities which serve as distinct operationalizations for each dimension. The two-tier account achieves three valuable aims: First, it separates strong and weak indicators of the presence of consciousness. (...)
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  7. Algorithmic Profiling as a Source of Hermeneutical Injustice.Silvia Milano & Carina Prunkl - forthcoming - Philosophical Studies:1-19.
    It is well-established that algorithms can be instruments of injustice. It is less frequently discussed, however, how current modes of AI deployment often make the very discovery of injustice difficult, if not impossible. In this article, we focus on the effects of algorithmic profiling on epistemic agency. We show how algorithmic profiling can give rise to epistemic injustice through the depletion of epistemic resources that are needed to interpret and evaluate certain experiences. By doing so, we not only (...)
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  8.  55
    Profiling and Proof: Are Statistics Safe?Georgi Gardiner - 2020 - Philosophy 95 (2):161-183.
    Many theorists hold that outright verdicts based on bare statistical evidence are unwarranted. Bare statistical evidence may support high credence, on these views, but does not support outright belief or legal verdicts of culpability. The vignettes that constitute the lottery paradox and the proof paradox are marshalled to support this claim. Some theorists argue, furthermore, that examples of profiling also indicate that bare statistical evidence is insufficient for warranting outright verdicts.I examine Pritchard's and Buchak's treatments of these three kinds (...)
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  9. Profiling, Neutrality, and Social Equality.Lewis Ross - 2022 - Australasian Journal of Philosophy 100 (4):808-824.
    I argue that traditional views on which beliefs are subject only to purely epistemic assessment can reject demographic profiling, even when based on seemingly robust evidence. This is because the moral failures involved in demographic profiling can be located in the decision not to suspend judgment, rather than supposing that beliefs themselves are a locus of moral evaluation. A key moral reason to suspend judgment when faced with adverse demographic evidence is to promote social equality—this explains why positive (...)
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  10. Profile Evidence, Fairness, and the Risks of Mistaken Convictions.Marcello Di Bello & Collin O’Neil - 2020 - Ethics 130 (2):147-178.
    Many oppose the use of profile evidence against defendants at trial, even when the statistical correlations are reliable and the jury is free from prejudice. The literature has struggled to justify this opposition. We argue that admitting profile evidence is objectionable because it violates what we call “equal protection”—that is, a right of innocent defendants not to be exposed to higher ex ante risks of mistaken conviction compared to other innocent defendants facing similar charges. We also show why admitting other (...)
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  11. Racial Profiling and a Reasonable Sense of Inferior Political Status.Adam Omar Hosein - 2018 - Journal of Political Philosophy 26 (3):1-20.
    This paper presents a novel framework for evaluating racial profiling, including 'rational profiling' that does in fact decrease crime rates. It argues that while profiling some groups, such as African Americans and Muslims, is impermissible, profiling others, such as white men, may be permissible. The historical and sociological context matters significantly. Along the way, the paper develops a new theory of what expressive harms are, why they matter, and when it is the responsibility of the state (...)
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  12.  23
    Latent profiles of ethical climate and nurses’ service behavior.Na Zhang, Dingxin Xu, Xing Bu & Zhen Xu - 2023 - Nursing Ethics 30 (4):626-641.
    Background Hospital ethical climate has important implications for clinical nurses’ service behavior; however, the relationships are complicated by the fact that five types of ethical climate (caring, law and code, rules, instrumental, and independence) can be combined differently according to their level and shape differences. Recent developments in person-centered methods (e.g., latent profile analysis (LPA)) have helped to address these complexities. Aim From a person-centered perspective, this study explored the distinct profiles of hospital ethical climate and then examined the relationships (...)
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  13. Argumentation profiles and the manipulation of common ground. The arguments of populist leaders on Twitter.Fabrizio Macagno - 2022 - Journal of Pragmatics 191:67-82.
    The detection of hate speech and fake news in political discourse is at the same time a crucial necessity for democratic societies and a challenge for several areas of study. However, most of the studies have focused on what is explicitly stated: false article information, language that expresses hatred, derogatory expressions. This paper argues that the explicit dimension of manipulation is only one – and the least problematic – of the risks of political discourse. The language of the unsaid is (...)
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  14.  51
    Identity, profiling algorithms and a world of ambient intelligence.Katja Vries - 2010 - Ethics and Information Technology 12 (1):71-85.
    The tendency towards an increasing integration of the informational web into our daily physical world (in particular in so-called Ambient Intelligent technologies which combine ideas derived from the field of Ubiquitous Computing, Intelligent User Interfaces and Ubiquitous Communication) is likely to make the development of successful profiling and personalization algorithms, like the ones currently used by internet companies such as Amazon, even more important than it is today. I argue that the way in which we experience ourselves necessarily goes (...)
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  15. Profiled hands in Palaeolithic art: the first universally recognized symbol of the human form.James W. P. Walker, David T. G. Clinnick & Jan B. W. Pedersen - 2018 - World Art 8 (1):1-19.
    Drawing on both anthropology and philosophy, this paper argues that the profiled form of the human hand is a universally recognizable image; one whose significance transcends temporally and geographically defined cultural divisions, and represents the earliest known artistic symbol of the human form. The unique co-occurrence of five properties in the image of the human hand and the way it is recognized support this argument, including that it is: (1) unmistakably a hand, (2) unmistakably human, (3) a universal point of (...)
     
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  16. Argumentation Profiles.Fabrizio Macagno - 2022 - Informal Logic 42 (4):83-138.
    An argumentation profile is defined as a methodological instrument for analyzing argumentative discourse considering distinct and interrelated dimensions: the types of argument used, their quality, and the emotions triggered. Walton’s theoretical contributions are developed as a coherent analytical and multifaceted toolbox for capturing these aspects. Argumentation schemes are used to detect and quantify the types of argument. Fallacy analysis and the assessment of the implicit premises retrieved through the schemes allow evaluating arguments. Finally, the frequency of emotive words signals the (...)
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  17. Racial Profiling and Criminal Justice.Jesper Ryberg - 2011 - The Journal of Ethics 15 (1-2):79 - 88.
    According to the main argument in favour of the practice of racial profiling as a low enforcement tactic, the use of race as a targeting factor helps the police to apprehend more criminals. In the following, this argument is challenged. It is argued that, given the assumption that criminals are currently being punished too severely in Western countries, the apprehension of more criminals may not constitute a reason in favour of racial profiling at all.
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  18.  19
    Affective Profiles and Anxiety or Non-Anxiety-Related Reasons for School Refusal Behavior: Latent Profile Analysis in Spanish Adolescents.Carolina Gonzálvez, Ángela Díaz-Herrero, María Vicent, Ricardo Sanmartín, Aitana Fernández-Sogorb & Cecilia Ruiz-Esteban - 2021 - Frontiers in Psychology 12.
    Little has been studied on the relationship between affect and school problems related with attendance. This study aims to identify different affective profiles and to determine whether these profiles differ from each other based on the four functional conditions of school refusal behavior. Participants comprised 1,816 Spanish adolescents aged 15–18 years. The Positive and Negative Affect Schedule for Children-Short Form and the School Refusal Assessment Scale-Revised for Children were administered. Latent profile analysis revealed five affective profiles: low affective profile, self-fulfilling (...)
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  19. Racial Profiling.Mathias Risse & Richard Zeckhauser - 2004 - Philosophy and Public Affairs 32 (2):131-170.
    We have benefited from conversations with Archon Fung, Brian Jacob, Todd Pittinsky, Peter Schuck, Ani Satz, Andrew Williams, and students in a joint class on statistics and ethics at the John F. Kennedy School of Government in October 2002. We are also grateful to our audience at the conference “The Priority of Practice,” organized by Jonathan Wolff at University College London in September 2003, and to Arthur Applbaum, Miriam Avins, Frances Kamm, Simon Keller, Frederick Schauer, Alan Wertheimer, and the Editors (...)
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  20.  88
    Racial Profiling and the Presumption of Innocence.Peter DeAngelis - 2014 - Netherlands Journal of Legal Philosophy (1):43-58.
    I argue that a compelling way to articulate what is wrong with racial profiling in policing is to view racial profiling as a violation of the presumption of innocence. I discuss the communicative nature of the presumption of innocence as an expression of social trust and a protection against the social condemnation of being undeservingly investigated, prosecuted, and convicted for committing a crime. I argue that, given its communicative dimension, failures to extend the presumption of innocence are an (...)
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  21.  36
    Emotion Profiles in the Dreams of Men and Women.Jane M. Merritt, Robert Stickgold, Edward Pace-Schott, Julie Williams & J. Allan Hobson - 1994 - Consciousness and Cognition 3 (1):46-60.
    We have investigated the emotional profile of dreams and the relationship between dream emotion and cognition using a form that specifically asked subjects to identify emotions within their dreams. Two hundred dream reports were collected from 20 subjects, each of whom produced 10 reports. Compared to previous studies, our method yielded a 10-fold increase in the amount of emotion reported. Anxiety/fear was reported most frequently, followed, in order, by joy/elation, anger, sadness, shame/guilt, and, least frequently, affection/eroticism. Unexpectedly, there was no (...)
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  22. Racial profiling versus community.Kasper Lippert-Rasmussen - 2006 - Journal of Applied Philosophy 23 (2):191–205.
    abstract A police technique known as racial profiling draws on statistical beliefs about crime rates in racial groups. Supposing that such beliefs are true, and that racial profiling is effective in fighting crime, is such profiling morally justified? Recently, Risse and Zeckhauser have explored the racial profiling of African‐Americans and argued that justification is forthcoming from a utilitarian as well as deontological point of view. Drawing on criticisms made by G. A. Cohen of the incentives argument (...)
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  23. Racial profiling and jury trials.Annabelle Lever - 2009 - The Jury Expert 21 (1):20-35.
    How, if at all, should race figure in criminal trials with a jury? How far should attorneys be allowed or encouraged to probe the racial sensitivities of jurors and what does this mean for the appropriate way to present cases which involve racial profiling and, therefore, are likely to pit the words and actions of a white policeman against those of a young black man?
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  24. Is Racial Profiling a Legitimate Strategy in the Fight against Violent Crime?Neven Sesardić - 2018 - Philosophia 46 (4):981-999.
    Racial profiling has come under intense public scrutiny especially since the rise of the Black Lives Matter movement. This article discusses two questions: whether racial profiling is sometimes rational, and whether it can be morally permissible. It is argued that under certain circumstances the affirmative answer to both questions is justified.
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  25.  11
    Profiles and Critiques in Social Theory.Anthony Giddens & Fred Reinhard Dallmayr - 1982 - Univ of California Press.
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  26.  25
    Profiles of Dialogue for Repairing Faults in Arguments from Experts Opinion.Marcin Koszowy & Douglas Walton - 2017 - Logic and Logical Philosophy 26 (1):79-113.
    Using the profiles of dialogue method we identify a species of ad verecundiam fallacy that works by forestalling of questioning in arguments from expert opinion. A profile of dialogue is a graph structure used to model a sequence of speech acts surrounding both the putting forward of an argument and the response to it at the next moves in a dialogue. The method is applied to a case of cross-examining a software engineer in a legal deposition in a case of (...)
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  27. Racial Profiling and Background Injustice.Paul Bou-Habib - 2011 - The Journal of Ethics 15 (1-2):33 - 46.
    Racial profiling appears to be morally more troubling when the racial group that is the object of the profile suffers from background injustice. This article examines two accounts of this intuition. The responsibility-based account maintains that racial profiling is morally more problematic if the higher offender rate within the profiled group is the result of social injustices for which other groups in society are responsible. The expressive harm based account maintains that racial profiling is more problematic if (...)
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  28.  54
    Profiling and the rule of law.Mireille Hildebrandt - 2008 - Identity in the Information Society 1 (1):55-70.
    Both corporate and global governance seem to demand increasingly sophisticated means for identification. Supposedly justified by an appeal to security threats, fraud and abuse, citizens are screened, located, detected and their data stored, aggregated and analysed. At the same time potential customers are profiled to detect their habits and preferences in order to provide for targeted services. Both industry and the European Commission are investing huge sums of money into what they call Ambient Intelligence and the creation of an ‘Internet (...)
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  29.  7
    Entrepreneurial Profiles at the University: A Competence Approach.Sofía Louise Martínez-Martínez & Rafael Ventura - 2020 - Frontiers in Psychology 11.
    The Entrepreneurial University plays a central role in entrepreneurial ecosystems and actively influences the development of entrepreneurial human capital, which is a critical asset for many economies. There is thus a requirement for the identification and strengthening of entrepreneurial competences, but no previous studies have included any analysis of these competences in the university context using an approach based on profiles. The present study fills this gap by investigating the existence of different entrepreneurial profiles among students, based on their competences. (...)
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  30. Identity, profiling algorithms and a world of ambient intelligence.Katja de Vries - 2010 - Ethics and Information Technology 12 (1):71-85.
    The tendency towards an increasing integration of the informational web into our daily physical world (in particular in so-called Ambient Intelligent technologies which combine ideas derived from the field of Ubiquitous Computing, Intelligent User Interfaces and Ubiquitous Communication) is likely to make the development of successful profiling and personalization algorithms, like the ones currently used by internet companies such as Amazon , even more important than it is today. I argue that the way in which we experience ourselves necessarily (...)
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  31.  34
    A profile of mathematical logic.Howard DeLong - 1970 - Mineola, N.Y.: Dover Publications.
    Anyone seeking a readable and relatively brief guide to logic can do no better than this classic introduction. A treat for both the intellect and the imagination, it profiles the development of logic from ancient to modern times and compellingly examines the nature of logic and its philosophical implications. No prior knowledge of logic is necessary; readers need only an acquaintance with high school mathematics. The author emphasizes understanding, rather than technique, and focuses on such topics as the historical reasons (...)
  32.  12
    Profile of hospital transplant ethics committees in the Philippines.Mary Ann Abacan - 2021 - Developing World Bioethics 21 (3):139-146.
    In the Philippines, all transplant centers are mandated by the Department of Health (DOH) to have a Hospital Transplant Ethics Committee (HTEC) to ensure that donations are altruistic, voluntary and free of coercion/commercial transactions. This study was undertaken primarily to describe the organizational and functional profile of existing HTECs and identify areas for improvement. This is a descriptive cross‐sectional study. There was variation in their logistical arrangements (support from hospital, filing systems, office spaces), operations (length and frequency of meetings, number (...)
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  33.  42
    Profiling, Information Collection and the Value of Rights Argument.Alan Rubel - 2013 - Criminal Justice Ethics 32 (3):1-21.
    In the United States and elsewhere, there is substantial controversy regarding the use of race and ethnicity by police in determining whom to stop, question, and investigate in relation to crime and security issues. In the ethics literature, the debate about profiling largely focuses on the nature of profiling and when (if ever) profiling is morally justifiable. This essay addresses the related, but distinct, issue of whether states have a duty to collect information about the race and (...)
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  34.  89
    Profiling Color.J. Angelo Corlett - 2011 - The Journal of Ethics 15 (1-2):21 - 32.
    This paper examines philosophically the nature and possible moral justification of racial profiling in terms of color profiling. Precisely what is such profiling, and can it ever be morally justified? If so, under what conditions is it morally justified?
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  35. Racial Profiling And Cumulative Injustice.Andreas Mogensen - 2017 - Philosophy and Phenomenological Research 98 (2):452-477.
    This paper tries to explain why racial profiling involves a serious injustice and to do so in a way that avoids the problems of existing philosophical accounts. An initially plausible view maintains that racial profiling is pro tanto wrong in and of itself by violating a constraint on fair treatment that is generally violated by acts of statistical discrimination based on ascribed characteristics. However, consideration of other cases involving statistical discrimination suggests that violating a constraint of this kind (...)
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  36. Dialectical Profiles and Indicators of Argumentative Moves.A. Francisca Snoeck Henkemans, Peter Houtlosser, Frans Eemeren & Frans H. van Eemeren - 2015 - In Scott Jacobs, Sally Jackson, Frans Eemeren & Frans H. van Eemeren (eds.), Reasonableness and Effectiveness in Argumentative Discourse: Fifty Contributions to the Development of Pragma-Dialectics. Cham, Switzerland: Springer Verlag.
     
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  37.  38
    Profiles of Emotion-antecedent Appraisal: Testing Theoretical Predictions across Cultures.KlausR Scherer - 1997 - Cognition and Emotion 11 (2):113-150.
  38.  11
    Argumentation Profiles.Fabrizio Macagno - 2022 - Informal Logic 44 (1):83-138.
    An argumentation profile is defined as a methodological instrument for analyzing argumentative discourse considering distinct and interrelated dimensions: the types of argument used, their quality, and the emotions triggered. Walton’s theoretical contributions are developed as a coherent analytical and multifaceted toolbox for capturing these aspects. Argumentation schemes are used to detect and quantify the types of argument. Fallacy analysis and the assessment of the implicit premises retrieved through the schemes allow evaluating arguments. Finally, the frequency of emotive words signals the (...)
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  39.  83
    Profiles of Dialogue for Evaluating Arguments from Ignorance.Douglas Walton - 1999 - Argumentation 13 (1):53-71.
    This investigation uses the technique of the profile of dialogue as a tool for the evaluation of arguments from ignorance (also called lack-of-evidence arguments, negative evidence, ad ignorantiam arguments and ex silentio arguments). Such arguments have traditionally been classified as fallacies by the logic textbooks, but recent research has shown that in many cases they can be used reasonably. A profile of dialogue is a connected sequence of moves and countermoves in a conversational exchange of a type that is goal-directed (...)
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  40.  70
    Ethical Profiling.Michael Boylan - 2011 - The Journal of Ethics 15 (1-2):131 - 145.
    This essay will argue for ethical procedures governing criminal profiling. A model based upon psychological/behavioral data, witness data, and forensic profiling data is sketched out. This model fits the legitimate uses of criminal profiling as an investigation procedure. Racial profiling as a primary sorting factor does not fit the preferred model and has significant downsides and so is rejected as a primary sorting mechanism in criminal investigation procedure.
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  41.  70
    Activity Profile and Physical Performance of Match Play in Elite Futsal Players.João Nuno Ribeiro, Bruno Gonçalves, Diogo Coutinho, João Brito, Jaime Sampaio & Bruno Travassos - 2020 - Frontiers in Psychology 11.
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  42.  5
    Profiling interest relativity.Deliagraff Fara - 2008 - Analysis 68 (4):326-335.
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  43. Why Racial Profiling Is Hard to Justify: A Response to Risse and Zeckhauser.Annabelle Lever - 2004 - Philosophy and Public Affairs 33 (1):94-110.
    In their article, “Racial Profiling,” Risse and Zeckhauser offer a qualified defense of racial profiling in a racist society, such as the contemporary United States of America. It is a qualified defense, because they wish to distinguish racial profiling as it is, and as it might be, and to argue that while the former is not justified, the latter might be. Racial profiling as it is, they recognize, is marked by police abuse and the harassment of (...)
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  44.  27
    Intensity profiles of emotional experience over time.Philippe Verduyn, Iven Van Mechelen, Francis Tuerlinckx, Kristof Meers & Hermina Van Coillie - 2009 - Cognition and Emotion 23 (7):1427-1443.
  45.  16
    High‐Profile Research and the Media: The Case of the Abio‐Cor Artificial Heart.E. Haavi Morreim - 2004 - Hastings Center Report 34 (1):11-24.
    Public discussion of new medical trials is desirable, but not moment‐by‐moment disclosure of patients' ups and down. Nor is such disclosure necessary: the public is not entitled to all information about a trial as soon as it is available. What should be given the press, and what withheld, cannot be decided without appreciating the surprising number and intricate interrelations of the parties' needs and interests.
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  46.  5
    Longitudinal Profiles of Psychological Well-Being and Health: Findings From Japan.Jiah Yoo & Carol D. Ryff - 2019 - Frontiers in Psychology 10.
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  47. Profiling interest relativity.Delia Graff Fara - 2008 - Analysis 68 (4):326-335.
  48.  26
    Profiles of the Virtues.Christine Swanton - 1995 - Pacific Philosophical Quarterly 76 (1):47-72.
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  49. Self-Profile.Roderick Chisholm - 1985 - In R. Bogdan (ed.), Roderick M. Chisholm. Reidel.
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  50.  20
    Distinct Profiles for Beliefs About Religion Versus Science.S. Emlen Metz, Emily G. Liquin & Tania Lombrozo - 2023 - Cognitive Science 47 (11):e13370.
    A growing body of research suggests that scientific and religious beliefs are often held and justified in different ways. In three studies with 707 participants, we examine the distinctive profiles of beliefs in these domains. In Study 1, we find that participants report evidence and explanatory considerations (making sense of things) as dominant reasons for beliefs across domains. However, cuing the religious domain elevates endorsement of nonscientific justifications for belief, such as ethical considerations (e.g., believing it encourages people to be (...)
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