Antibody-based fiberoptics biosensor for the carcinogen benzopyrene

Abstract

A new antibody-based fiberoptics biosensor was used to detect the important carcinogen benzopyrene. The fiberoptics sensor utilizes anti-BaP antibodies covalently bound to its tip. A helium cadmium laser was used as the excitation source to induce fluorescence from BaP conjugated to the bound anti-BaP antibodies. The fiberoptics device can detect 1 femtomole of BaP in a 5- mu L sample drop.

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