The pregnancy compensation hypothesis, not the staying alive theory, accounts for disparate autoimmune functioning of women around the world

Behavioral and Brain Sciences 45 (2022)
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Abstract

The pregnancy compensation hypothesis provides a mechanistic explanation for the evolution of sex differences in immune system functioning, the excess of women experiencing autoimmune disease, and why this is observed only in industrialized nations; none of which can be explained by the staying alive theory, as proposed by the authors of the target article.

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