Can Central IRBs Replace Local Review?

Journal of Law, Medicine and Ethics 45 (3):348-351 (2017)
  Copy   BIBTEX

Abstract

The NIH has initiated a plan to mandate use of central IRBs for all multi-site research. This manuscript argues against the mandate, proposing that there is inadequate evidence to support the purported gains in efficiency and that the ethical integrity of research may suffer with any exclusion of the local review voice.

Categories

Add categories

Keywords

Reprint years

DOI

10.1177/1073110517737533

Links

PhilArchive



    Upload a copy of this work     Papers currently archived: 92,923

External links

Setup an account with your affiliations in order to access resources via your University's proxy server

Through your library

My notes

Similar books and articles

How local IRBs view central IRBs in the US.Robert Klitzman - 2011 - BMC Medical Ethics 12 (1):13.
Research ethics committees: A regional approach.Cheryl Cox Macpherson - 1999 - Theoretical Medicine and Bioethics 20 (2):161-179.
Behind Closed Doors: Irbs and the Making of Ethical Research.Laura Stark - 2011 - University of Chicago Press.
Corrigenda.A. N. Whitehead - 1934 - Mind 43 (172):543.
Views and Experiences of IRBs Concerning Research Integrity.Robert Klitzman - 2011 - Journal of Law, Medicine and Ethics 39 (3):513-528.
The Nuts and Bolts of IRBs.Don Workman - 2007 - IRB: Ethics & Human Research 29 (2).
Us irbs confronting research in the developing world.Robert L. Klitzman - 2012 - Developing World Bioethics 12 (2):63-73.
How Independent Are IRBs?Ruth Macklin - 2008 - IRB: Ethics & Human Research 30 (3).
How US institutional review boards decide when researchers need to translate studies.Robert Klitzman - 2014 - Journal of Medical Ethics 40 (3):193-197.
A case study of researchers’ knowledge and opinions about the ethical review process for research in Botswana.Dimpho Ralefala, Joseph Ali, Nancy Kass & Adnan Hyder - 2018 - Research Ethics 14 (1):1-14.
Federal Commissions and Local IRBs.Michael S. Yesley - 1983 - Hastings Center Report 13 (5):11-12.
The Right to Participate in High-Risk Research.David Shaw - 2014 - The Lancet 38:1009 – 1011.
What are local issues? The problem of the local review of research.P. Wainwright - 2004 - Journal of Medical Ethics 30 (3):313-317.
Protecting Research Subjects: IRBs in a Changing Research Landscape.Ann Cook & Helena Hoas - 2011 - IRB: Ethics & Human Research 33 (2):14-19.
Multicenter trials and subject eligibility: should local IRBs play a role?Benjamin Freedman - 1994 - IRB: Ethics & Human Research 16 (1-2):1.

Analytics

Added to PP
2017-10-25

Downloads
13 (#1,061,253)

6 months
3 (#1,037,581)

Historical graph of downloads
How can I increase my downloads?

Citations of this work

Controversies in Clinical Research Ethics.Robert M. Sade - 2017 - Journal of Law, Medicine and Ethics 45 (3):291-294.

Add more citations

References found in this work

No references found.

Add more references