Integration of approaches in David Wake’s model-taxon research platform for evolutionary morphology

Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 44 (4):525-536 (2013)
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Abstract

What gets integrated in integrative scientific practices has been a topic of much discussion. Traditional views focus on theories and explanations, with ideas of reduction and unification dominating the conversation. More recent ideas focus on disciplines, fields, or specialties; models, mechanisms, or methods; phenomena, problems. How integration works looks different on each of these views since the objects of integration are ontologically and epistemically various: statements, boundary conditions, practices, protocols, methods, variables, parameters, domains, laboratories, and questions all have their own structures, functions and logics. I focus on one particular kind of scientific practice, integration of “approaches” in the context of a research system operating on a special kind of “platform.” Rather than trace a network of interactions among people, practices, and theoretical entities to be integrated, in this essay I focus on the work of a single investigator, David Wake. I describe Wake’s practice of integrative evolutionary biology and how his integration of approaches among biological specialties worked in tandem with his development of the salamanders as a model taxon, which he used as a platform to solve, re-work and update problems that would not have been solved so well by non-integrative approaches. The larger goal of the project to which this paper contributes is a counter-narrative to the story of 20th century life sciences as the rise and march of the model organisms and decline of natural history

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James Griesemer
University of California, Davis

Citations of this work

Systems biology and the integration of mechanistic explanation and mathematical explanation.Ingo Brigandt - 2013 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 44 (4):477-492.
Dimensions of integration in interdisciplinary explanations of the origin of evolutionary novelty.Alan C. Love & Gary L. Lugar - 2013 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 44 (4):537-550.
Evo-Devo as a Trading Zone.Rasmus Grønfeldt Winther - 2015 - In Alan C. Love (ed.), Conceptual Change in Biology: Scientific and Philosophical Perspectives on Evolution and Development. Berlin: Springer Verlag, Boston Studies in the Philosophy of Science.

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References found in this work

Explanatory unification and the causal structure of the world.Philip Kitcher - 1989 - In Philip Kitcher & Wesley Salmon (eds.), Scientific Explanation. Minneapolis: University of Minnesota Press. pp. 410-505.
Interfield theories.Lindley Darden & Nancy Maull - 1977 - Philosophy of Science 44 (1):43-64.
Reductionism in Biology.Ingo Brigandt & Alan Love - 2008 - The Stanford Encyclopedia of Philosophy.
The roles of integration in molecular systems biology.Maureen A. O’Malley & Orkun S. Soyer - 2012 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 43 (1):58-68.

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