ESRC Centre for Genomics in Society University of Exeter

Perspectives on Science 12 (3):320-338 (2004)
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Abstract

. Recent molecular biology has seen the development of genomics as a successor to traditional genetics. This paper offers an overview of the structure, epistemology, and history of contemporary genomics. A particular focus is on the question to what extent the genome contains, or is composed of anything that corresponds to traditional conceptions of genes. It is concluded that the only interpretation of genes that has much contemporary scientific relevance is what is described as the “developmental defect” gene concept. However, developmental defect genes typically only correspond to general areas of the genome and not to precise chemical structures. The parts of the genome to be identified for an account of the processes of normal development are highly diverse, little correlated with traditional genes, and act in ways that are highly dependent on the cellular and higher level environment. Despite its historical development out of genetics, genomics represents a radically different kind of scientific project.

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John Dupre
University of Exeter

References found in this work

The methodology of scientific research programmes.Imre Lakatos - 1978 - New York: Cambridge University Press.
Philosophy of biological science.David L. Hull - 1974 - Englewood Cliffs, N.J.,: Prentice-Hall.
What Genes Can't Do.Lenny Moss - 2003 - MIT Press.
Genes made molecular.C. Kenneth Waters - 1994 - Philosophy of Science 61 (2):163-185.

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