Thalamocortical dysfunction and complex visual hallucinations in brain disease – are the primary disturbances in the cerebral cortex?

Behavioral and Brain Sciences 27 (6):789-790 (2004)
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Abstract

Applying Behrendt & Young's (B&Y's) model of thalamocortical synchrony to complex visual hallucinations in neurodegenerative disorders, such as dementia with Lewy bodies and progressive supranuclear palsy, leads us to propose that the primary pathology may be cortical rather than thalamic. Additionally, the extinction of active hallucinations by eye closure challenges their conception of the role of reduced sensory input.

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