Different types of consent are used to obtain human biospecimens for future research. This variation has resulted in confusion regarding what research is permitted, inadvertent constraints on future research, and research proceeding without consent. The National Institutes of Health Clinical Center's Department of Bioethics held a workshop to consider the ethical acceptability of addressing these concerns by using broad consent for future research on stored biospecimens. Multiple bioethics scholars, who have written on these issues, discussed the reasons for consent, the (...) range of consent strategies, and gaps in our understanding, and concluded with a proposal for broad initial consent coupled with oversight and, when feasible, ongoing provision of information to donors. This article describes areas of agreement and areas that need more research and dialogue. Given recent proposed changes to the Common Rule, and new guidance regarding storing and sharing data and samples, this is an important and tim.. (shrink)

La experiencia de hacer filosofía en la escuela como práctica de libertad nos convoca al análisis de los modos de recepción de la filosofía en la Argentina y Latinoamérica. Dicho de otra manera, el planteo de Filosofía con Niñ@s requiere reponer el problema de filosofía latinoamericana o filosofía en Latinoamérica; y, con ello, tematizar la "antinomia/oposición/ alternativa" de estos términos en relación con prácticas filosóficas no reproductivas, de gratuidad del pensar, de anulación de la asimetría a la hora del filosofar.

In 1906, Frigyes Riesz introduced a preliminary version of the notion of a topological space. He called it a mathematical continuum. This development can be traced back to the end of 1904 when, genuinely interested in taking up Hilbert’s foundations of geometry from 1902, Riesz aimed to extend Hilbert’s notion of a two-dimensional manifold to the three-dimensional case. Starting with the plane as an abstract point-set, Hilbert had postulated the existence of a system of neighbourhoods, thereby introducing the notion of (...) an accumulation point for the point-sets of the plane. Inspired by Hilbert’s technical approach, as well as by recent developments in analysis and point-set topology in France, Riesz defined the concept of a mathematical continuum as an abstract set provided with a notion of an accumulation point. In addition, he developed further elementary concepts in abstract point-set topology. Taking an abstract topological approach, he formulated a concept of three-dimensional continuous space that resembles the modern concept of a three-dimensional topological manifold. In 1908, Riesz presented his concept of mathematical continuum at the International Congress of Mathematicians in Rome. His lecture immediately won the attention of people interested in carrying on his research. They promoted his ideas, thus assuring their gradual reception by several future founders of general topology. In this way, Riesz’s work contributed significantly to the emergence of this discipline. (shrink)