Biography is one of the most popular categories of books—and indeed the most popular category among nonfiction books, according to one British poll. Thus, biography offers historians of science an opportunity to reach a potentially broad audience. This essay examines approaches typical of different genres of scientific biography, including historians’ motivations in their choices of biographical subject and their decisions about strategies for reconstruction of the biographical life. While historians of science often use biography as a vehicle to analyze scientific (...) processes and scientific culture, the most compelling scientific biographies are ones that portray the ambitions, passions, disappointments, and moral choices that characterize a scientist’s life. (shrink)