There is a bias in neuroscience toward localizing and modularizing brain functions. Single cell recording, imaging studies, and the study of neurological deficits all feed into the Gallian view that different brain areas do different things and the things being done are confined to particular processing streams. At the same time, there is a growing sentiment that brains probably don’t work like that after all; it is better to conceive of them as fundamentally distributed units, multi‐tasking at every level. This (...) sentiment, however, is much less congenial to the tried‐and‐true experimental protocols available today and to theorizing about the brain in general. This essay examines the tension between current experimental methods and large-scale views of the brain. We argue that this disconnection between experiment and what really are guiding theoretical metaphors seriously impedes progress in neuroscience. (shrink)

There is a bias in neuroscience toward localizing and modularizing brain functions. Single cell recording, imaging studies, and the study of neurological deficits all feed into the Gallian view that different brain areas do different things and the things being done are confined to particular processing streams. At the same time, there is a growing sentiment that brains probably don’t work like that after all; it is better to conceive of them as fundamentally distributed units, multi‐tasking at every level. This (...) sentiment, however, is much less congenial to the tried‐and‐true experimental protocols available today and to theorizing about the brain in general. This essay examines the tension between current experimental methods and large-scale views of the brain. We argue that this disconnection between experiment and what really are guiding theoretical metaphors seriously impedes progress in neuroscience. (shrink)

This article examines how scientists move from physical measurementsto actual observation of single-cell recordings in the brain. We highlight how easy it is to change the fundamental nature of ourobservations using accepted methodological techniques for manipulatingraw data. Collecting single-cell data is thoroughly pragmatic. Weconclude that there is no deep or interesting difference betweenaccounting for observations by measurements and accounting forobservations by theories.

Conditional information can be equally asserted in the forms if p, then q (e.g., ?if I am ill, I will miss work tomorrow?) and q, if p (e.g., ?I will miss work tomorrow, if I am ill?). While this type of clause order manipulation has previously been found to have no influence on the ultimate conclusions participants draw from conditional rules, we used self-paced reading to examine how it affects the real time incremental processing of everyday conditional statements. Experiment 1 (...) revealed that clause order interacts with presuppositional congruency as readers hypothetically represent counterfactual statements. When if p, then q counterfactuals contained a presupposition that was incongruent with prior context, these statements took longer to read than when the presupposition was congruent, but for q, if p conditionals there was no such congruency effect. Experiment 2 revealed that reading times were influenced by the subjective probability of an indicative conditional regardless of clause order, with a penalty observed for low-probability statements relative to high-probability statements in both conditional clause orders. These data reveal a dissociation whereby clause order mediates the effect of suppositional congruency on reading times, but does not mediate the effect of subjective probability. (shrink)

For those in the so‐called G‐7, G‐8, or G‐20, searching for the formula for economic takeoff, this is a book that deserves a reckoning. It explores the “role of culture,” which hitherto has had “no place in traditional economic explanations” of the history of industrial achievement. It is in the cultural and epistemological transformation of the eighteenth century that Margaret Jacob finds the foundation of industrial revolution. Jacob thereby dismisses the myth of the accidental genius or the inspired semiliterate backyard (...) tinkerer that has reinforced the notion that nothing can be done except by lives of singular initiative.By comparing the British most particularly with the Dutch and the French, Jacob argues it was precisely the utilitarian and egalitarian sentiments found in British scientific and philosophical societies that mattered most. Her theme is the much‐contested vision of the efficacy of natural knowledge and the assimilation of natural philosophy by the utilitarian world of the artisan and the entrepreneur. The advance of mechanical philosophy under Galileo and Descartes notwithstanding, it was during the English Revolution of the mid‐seventeenth century that natural philosophy was explicitly attached to a new social reformation and an inchoate democratic vision.Isaac Newton had nothing but derision for the vulgar “inferior horde of people” . Yet his disciples launched into careers as purveyors of his science in public lectures heavily weighted to mechanical explanation. Often viewed with suspicion elsewhere in Europe, in England such lecturers flourished. Even the engineer James Watt's French contact J. C. Perier, who desperately sought as many British secrets as possible, had initially learned his science from the lecturer abbé Nollet. An increasing awareness of the practical consequences of the new science was essential to the economic achievements of the late Enlightenment. This ultimately is a major thrust of Jacob's argument, for many early industrialists “were smarter than historians have allowed them to be” . Those who sought the new steam engines for their mines were perfectly well aware of the mechanical limitations and natural variables that might affect the success of their enterprise. Jacob is quite correct that “the Baconian vision lived on, eventually subsumed under the larger rubric of Newtonianism” . At the end of the century, the Napoleonic technocrat Jean‐Antoine Chaptal appears as representative of the case for applied science by promoting the Baconian unity of theory and practice.The most innovative part of Jacob's story is the attention she pays to the role of science in the attitudes of Midlands entrepreneurs like James Watt and Matthew Boulton. Both insisted on a scientific education for their sons, and Boulton recommended as much for the sons of foreign visitors to the Soho foundry. Both Watt and Boulton were particularly adept in the experimental laboratory, although they were also highly suspicious of the growing public technical interest and scientific curiosity that they feared might undermine their own patent monopoly. This suspicion grew out of their own deeper unease at the burgeoning democratic sympathies. Boulton and James Watt, senior, were extremely critical of radicalism—so we need not, therefore, draw any simple equation between industrial innovation and political reform. The currents of late eighteenth‐century Britain were far too complicated for that. Jacob, nonetheless, draws broad and interesting conclusions about the ways in which Continental cultural and political factors obstructed the spread of the very natural knowledge that gave the British such advantages. In her view, especially in this age of a “knowledge economy,” it might now do us well to remember the potential effects of “the widest dissemination of scientific knowledge” and “the democratization of learning” . In Jacob's version of the Industrial Revolution, the broadening and deepening of democracy followed the spread of natural learning beyond the uses of traditional elites. (shrink)

Abstract Employing an extended case method ethnography (Burawoy 1998), the researcher joined five new members forming a spiritualist's group under the leadership of an experienced advocate. Over a period of eighteen months, the researcher attended all the group's activities and events. Data were collected to reflexively interrogate the process theory of conversion proposed by Lewis Rambo (1993). The data revealed conversion to be a multifaceted and dynamic process of cognitive change, mediated by structural, and contextual forces. The results provide a (...) reconceptualization of Rambo's theory, presenting a theoretical expansion of the model emphasizing its mechanisms of action. The paper details the composition of the “Interaction-Commitment” mechanism, operationalized within four submechanisms emanating from Rambo's roles, rituals, rhetoric, and relationships. This longitudinal study shows that most of the hard work toward conversion occurs before any formal interaction with a conversion advocate. Conversion operates most effectively under conditions of cognitive economy wherein the belief path follows a path of least cognitive expenditure. (shrink)

The liver was used widely in early studies of polarised transport but has been largely overlooked in recent years, mostly because of the development of epithelial cell lines which provide more tractable experimental systems. The majority of membrane proteins and lipids reach the hepatocyte apical membrane by transcytosis and it remains unclear whether there is a direct route for apical targeting, although the pathways present have yet to be fully characterised. The recent development of systems that allow hepatocyte transport processes (...) to be studied in culture and the observation that transcytosis can be significantly stimulated under physiological conditions suggest that hepatocytes have a role to play in future studies of polarised transport. This review discusses the known features of polarised membrane traffic in hepatocytes and contrasts them with the characteristics of vesicular transport in other epithelial cell types. (shrink)

Postcolonial science studies entails ostensibly contradictory critical and empirical commitments. Science studies scholars influenced by Bruno Latour and Isabelle Stengers embrace forms of realist, radical empiricism, while postcolonial studies scholars influenced by Jacques Derrida trace the limits of the knowable. This essay takes their common use of the term cosmopolitics as an unexpected point of departure for reconciling Derrida’s program with Stengers’s and Latour’s. I read Derrida’s critique of hospitality and Stengers’s and Latour’s ontological politics as necessary complements for conceiving (...) a care-oriented subalternist cosmopolitics, a process of composing common worlds that remains attentive to the limits of representation. (shrink)

Recently, many philosophers of religion have sought to defend the rationality of religious belief by shifting the burden of proof onto the critic of religious belief. Some have appealed to extraordinary religious experience in making their case. Religious Experience, Justification, and History restores neglected explanatory and historical considerations to the debate. Through a study of William James, it contests the accounts of religious experience offered in recent works. Through reflection on the history of philosophy, it also unravels the philosophical use (...) of the term justification. Matthew Bagger argues that the commitment to supernatural explanations implicit in the religious experiences employed to justify religious belief contradicts the modern ideal of human flourishing. (shrink)

To study how religiosity affects family business goals, we merge literatures on goal setting, temporal orientation, and family business to argue that family business goals can be distinguished into short-term and long-term orientations and propose that religiosity affects both orientations, but to varying degrees. Drawing on a sample of private U.S. family businesses and applying partial least squares structural equations modeling, we find tentative support that religiosity has a stronger positive effect on long-term goal orientation than on short-term goal orientation. (...) We discuss implications for theory development and future research involving religiosity and family business goals. (shrink)

To study how religiosity affects family business goals, we merge literatures on goal setting, temporal orientation, and family business to argue that family business goals can be distinguished into short-term and long-term orientations and propose that religiosity affects both orientations, but to varying degrees. Drawing on a sample of private U.S. family businesses and applying partial least squares structural equations modeling, we find tentative support that religiosity has a stronger positive effect on long-term goal orientation than on short-term goal orientation. (...) We discuss implications for theory development and future research involving religiosity and family business goals. (shrink)

In this paper I respond to Robert Taylor's argument that a Rawlsian framework does not support strong affirmative action programs. The paper makes three main arguments. The first disputes Taylor's claim that strong AA would not be needed in ideal conditions. Private racial discrimination, I suggest, might still exist in such conditions, so strong AA might be needed there. The second challenges Taylor's claims that pure procedural justice constrains Rawlsian nonideal theory. I argue that this rests on a fetishizing of (...) pure procedural justice that is absent from Rawls's work. I also show that a revised formulation of Taylor's concern here also fails. My third argument makes a positive Rawlsian case for strong AA in nonideal conditions that builds on a Taylor concession. Taylor suggests that the goal of nonideal theory is to create a world in which ideal theory can be applied. My argument begins by showing that another permissible goal of Rawlsian nonideal theory is to ameliorate injustice. I then argue that Rawls's contractualist framework supports the strongest forms of AA when category 3 interventions are blocked. (shrink)

Attentional bias towards threat can be demonstrated by enhanced processing of threat-related targets and/or greater interference when threat-related distractors are present. These effects are argued to reflect processing within the orienting and executive control networks of the brain respectively. This study investigated behavioural and electrophysiological correlates of early selective attention and top-down attentional control among females with high or low spider fear. Participants completed a novel flanker go/nogo task in which a central schematic flower or spider stimulus was flanked by (...) either congruent or incongruent distractors. Participants responded to green stimuli and withheld response to yellow stimuli. High fear participants demonstrated significantly shorter reaction times and greater P1 amplitude to spider targets, suggesting specific hypervigilance towards threat-relevant stimuli. In contrast to predictions, there was little evidence for behavioural interference effects or differences in N2 amplitude when distractor stimuli were threat-relevant. (shrink)

The Fractured Self in Freud and German Philosophy examines Freud's transformation of German philosophical approaches to freedom, history, and self-knowledge; defends a theory of situated knowledge and agency; and considers the relevance of Freudian thought for contemporary cultural issues.

_Kant and Applied Ethics_ makes an important contribution to Kant scholarship, illuminating the vital moral parameters of key ethical debates. Offers a critical analysis of Kant’s ethics, interrogating the theoretical bases of his theory and evaluating their strengths and weaknesses Examines the controversies surrounding the most important ethical discussions taking place today, including abortion, the death penalty, and same-sex marriage Joins innovative thinkers in contemporary Kantian scholarship, including Christine Korsgaard, Allen Wood, and Barbara Herman, in taking Kant’s philosophy in new (...) and interesting directions Clarifies Kant’s legacy for applied ethics, helping us to understand how these debates have been structured historically and providing us with the philosophical tools to address them. (shrink)

When examined critically, Kant's views on sex and marriage give us the tools to defend same-sex marriage on moral grounds. The sexual objectification of one's partner can only be overcome when two people take responsibility for one another's overall well-being, and this commitment is enforced through legal coercion. Kant's views on the unnaturalness of homosexuality do not stand up to scrutiny, and he cannot (as he often tries to) restrict the purpose of sex to procreation. Kant himself rules out marriage (...) only when the partners cannot give themselves to one another equally – that is, if there is inequality of exchange. Because same-sex marriage would be between equals and would allow homosexuals to express their desire in a morally appropriate way, it ought to be legalized. (shrink)

Most ethics guidelines for distributing scarce medical resources during the coronavirus pandemic seek to save the most lives and the most life‐years. A patient’s prognosis is determined using a SOFA or MSOFA score to measure likelihood of survival to discharge, as well as a consideration of relevant comorbidities and their effects on likelihood of survival up to one or five years. Although some guidelines use age as a tiebreaker when two patients’ prognoses are identical, others refuse to consider age for (...) fear of discriminating against the elderly. In this paper, I argue that age is directly relevant for maximizing health benefits, so current ethics guidelines are wrongly excluding or deemphasizing life‐stage in their triage algorithms. Research on COVID‐19 has shown that age is a risk factor in adverse outcomes, independent of comorbidities. And limiting a consideration of life‐years to only one or five years past discharge does not maximize health benefits. Therefore, based on their own stated values, triage algorithms for coronavirus patients ought to include life‐stage as a primary consideration, along with the SOFA score and comorbidities, rather than excluding it or using it merely as a tiebreaker. This is not discriminatory because patients ought to have equal opportunity to experience life‐stages. The equitable enforcement of that right justifies unequal treatment based on age in cases when there is a scarcity of life‐saving resources. A consideration of life‐stage would thus allow healthcare workers to responsibly steward public resources in order to maximize lives and life‐years saved. (shrink)

The moral right to keep and bear arms is entailed by the moral right of self-defense. We argue that the ownership and use of firearms is a reasonable means of exercising these rights. Given their defensive value, there is a strong presumption in favor of enacting civil rights to keep and bear arms ranging from handguns to ‘assault rifles.’ Thus, states are morally obliged as a matter of justice to recognize basic liberties for firearm ownership and usage. Throughout this paper (...) we build upon the relevant criminological and social science research in addition to the work of other philosophers who have in recent years argued in favor of gun rights. Although we believe the statistical evidence supports our case, our argument is primarily non-consequentialist. We do, however, address consequentialist objections in the last section of this paper. (shrink)

The law and policy applicable to the not-for-profit sector is of growing importance around the world. In this book, legal experts address fundamental questions about not-for-profit law from a range of theoretical and comparative perspectives. The essays provide scholarly analysis of not-for-profit law, organised around four themes: Politics, in the broader sense of living as a community, and the narrower sense of political power; Charity, how it is defined and changes in its meaning over time; Taxation, including the rationale for (...) government support of the sector through the tax system; Regulation, which is of increasing significance as governments establish increasingly complex forms of regulation of not-for-profit activity. The fundamental aim of the book is to deepen our understanding of not-for-profit law and of the rationales and modes of government support for the not-for-profit sector. (shrink)

This remarkably comprehensive Handbook provides a multifaceted yet carefully crafted investigation into the work of Immanuel Kant, one of the greatest philosophers the world has ever seen. With original contributions from leading international scholars in the field, this authoritative volume first sets Kant’s work in its biographical and historical context. It then proceeds to explain and evaluate his revolutionary work in metaphysics and epistemology, logic, ethics, aesthetics, philosophy of science, philosophy of religion, political philosophy, philosophy of history, philosophy of education, (...) and anthropology. Key Features: • Draws attention to the foundations of Kant’s varied philosophical insights — transcendental idealism, logic, and the bridge between theoretical and practical reason • Considers hitherto neglected topics such as sexuality and the philosophy of education • Explores the immense impact of his ground-breaking work on subsequent intellectual movements Serving as a touchstone for meaningful discussion about Kant’s philosophical and historical importance, this definitive Handbook is essential reading for Kant scholars who want to keep abreast of the field and for advanced students wishing to explore the frontiers of the subject. (shrink)

Recently Robert Forman has attempted to muster support for the largely abandoned position that mystical experiences cross-culturally include an unmediated, non-relative core. To reopen the debate he has solicited essays from likeminded scholars for his book, The Problem of Pure Consciousness. Predictably the focus of the volume rests on the refutation of the position most notably expounded by Steven Katz in his influential article of 1978, ‘Language, Epistemology and Mysticism’.

Kant is gaining popularity in business ethics because the categorical imperative rules out actions such as deceptive advertising and exploitative working conditions, both of which treat people merely as means to an end. However, those who apply Kant in this way often hold businesses themselves morally accountable, and this conception of collective responsibility contradicts the kind of moral agency that underlies Kant's ethics. A business has neither inclinations nor the capacity to reason, so it lacks the conditions necessary for constraint (...) by the moral law. Instead, corporate policies ought to be understood as analogous to legal constraints. They may encourage or discourage certain actions, but they cannot determine a person's maxim - which for Kant is the focus of moral judgment. Because there is no collective intention apart from any intentions of the individual agents who act as members of the corporation, an organization itself has no moral obligations. This poses a dilemma: either apply the categorical imperative to the actions of particular businesspeople and surrender the notion of collective responsibility, or apply a different moral theory to the actions of businesses themselves. Given the diffusion of responsibility in a bureaucracy, the explanatory usefulness of collective responsibility may force business ethicists to abandon Kant's moral philosophy. (shrink)

What could ground normative restrictions concerning cultural appropriation which are not grounded by independent considerations such as property rights or harm? We propose that such restrictions can be grounded by considerations of intimacy. Consider the familiar phenomenon of interpersonal intimacy. Certain aspects of personal life and interpersonal relationships are afforded various protections in virtue of being intimate. We argue that an analogous phenomenon exists at the level of large groups. In many cases, members of a group engage in shared practices (...) that contribute to a sense of common identity, such as wearing certain hair or clothing styles or performing a certain style of music. Participation in such practices can generate relations of group intimacy, which can ground certain prerogatives in much the same way that interpersonal intimacy can. One such prerogative is making what we call an appropriation claim. An appropriation claim is a request from a group member that non-members refrain from appropriating a given element of the group’s culture. Ignoring appropriation claims can constitute a breach of intimacy. But, we argue, just as for the prerogatives of interpersonal intimacy, in many cases there is no prior fact of the matter about whether the appropriation of a given cultural practice constitutes a breach of intimacy. It depends on what the group decides together. (shrink)

This chapter contains sections titled: Sex Is Morally Problematic Sex Is (Conditionally) Good Exchanging Ourselves: Marriage in the Moralphilosophie Collins Kant and Political Liberalism Transforming Ourselves into Husbands and Wives: Marriage in the Metaphysics of Morals Is Something Wrong Because It Is Unnatural? Pleasure as an End of Nature Marital Equality as a Criterion of Legitimacy How the Same‐Sex Marriage Debate Should Proceed.

This chapter contains sections titled: The Moral Duty to Assist Others in Their Health Care Health Care Should Be Provided by the Government The Duty to Provide Truly Universal Health Care Rejecting the Liberal Model.

This chapter contains sections titled: Kant's Logocentrism Kant's Justification for Our Duties (with Regard) to Nonrational Animals Implications of Kant's View for Our Treatment of Animals Kantians Revising Kant: Wood and Korsgaard Problems with Wood and Korsgaard Kant's Response to Wolff: The Difference between Animal Choice and Moral Agency Evaluating Pain and Pleasure Kant's Practical Appeal Final Thoughts for the Nonanthropocentrist.

This chapter contains sections titled: The Ancient Practice of Abortion, and Continuing Controversies Universalized Maxims Are Not Retroactive The Formula of Humanity: Appealing to Personhood Thomson and Boonin: The Personhood of the Fetus Does Not Matter The Elements of Personhood: Self‐Consciousness, Humanity, Responsibility An Attempt to Bring Fetuses into Kant's Moral Community: The Appeal to Kind Another Common Strategy: The Argument from Potential Do We Have Indirect Duties to Fetuses? No Fetuses, No Children The Need for a Pragmatic Concept of (...) Personhood The Specter of Infanticide Kant's Appeal to God Problematic Implications of the Appeal to Personhood Our Kantian Heritage: Trouble with Those at the Margins of Personhood. (shrink)

This chapter contains sections titled: The Purpose of Marriage Consent and Coercion Mail‐Order Marriages as the Kantian Ideal Treating Mail‐Order Brides Merely as Means Attempts to Criticize Mail‐Order Marriages from a Kantian Perspective Are Mail‐Order Brides Coerced? Questioning the a priori Basis of Kant's Ethics Notes toward a Genealogy of Kantianism.

This chapter contains sections titled: How Kant Answers Hegel's Formalism Charge Basic Principles versus Particular Duties: Kant and Rawls What Is My Obligation to Reduce Poverty? Social Contexts Specify the Content of Maxims Herman's Rules of Moral Salience The Humanity of Others Is Not Simply Given Developing Moral Judgment: The Case of Kant Himself The Return of Hegel.

This chapter contains sections titled: Natural Purposiveness in the Critique of Judgment Furthering Nature's Purposes: The Stewardship Model The Value of Nature for Humanity Considering Future Generations Beauty as a Symbol of Morality Preserving the Sublime Developing Kantian Virtues Norton's Convergence Hypothesis and Light's Practical Pluralism The Appeal to Common Sense Kant's Place in the Debate over Environmental Policy.

This chapter contains sections titled: The Difference between Morality and Legality Retribution and the Death Penalty Consenting to Capital Punishment Determining the “Inner Wickedness” of the Accused The Fallibility of Justice Capital Punishment Cannot Be Categorically Demanded of Us A Moral Assessment of the Supposed Duty to Kill Do These Objections Rule Out All Punishments? Whose Dignity Is at Stake?

This chapter contains sections titled: Decision‐Making Procedures and Maxims in Corporate Settings The Need for Collective Responsibility in Business Ethics Applying the Categorical Imperative to Businesses Kant's Account of Moral Agency and the Categorical Imperative Must We Never Treat a Business Merely as a Means? Corporate Policies and Individual Agents Bowie's Defense of Collective Responsibility, and the Need for an Alternative Personal Responsibility within the Corporation The Choice Facing Business Ethicists: Kant or Collective Responsibility?

This chapter contains sections titled: Physician‐Assisted Suicide Refusing Life‐Saving Medical Treatment Organ Donation: Opt‐in or Opt‐out? Autonomy and the Body.

The disconnect problem arises wherever there is ongoing and severe discordance between the scientific assessment of a politically relevant issue, and the politics and legislation of said issue. Here, we focus on the disconnect problem as it arises in the case of climate change, diagnosing a failure to respect the necessary tradeoff between authority and autonomy within a public institution like science. After assessing the problematic deployment of scientific authority in this arena, we offer suggestions for how to mitigate climate (...) change’s particular disconnect problem, as well as more general proposals for reforming science advising. (shrink)

Although Kant defends a cosmopolitan ideal, his philosophy is problematically vague regarding how to achieve it, which lends support to the empty formalism charge. How Kant would respond to the crisis in Syria reveals that judgement plays too central a role, because Kantian principles lead to equally reasonable but opposite conclusions on how to weigh the duty of hospitality to refugees against a state’s duty to its own citizens, the right of prevention towards ISIS against the duty not to harm (...) non-combatants, and the responsibility to protect the people of Syria against the duty of non-interference in its internal affairs. (shrink)