Results for 'psilocybin'

61 found
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  1.  58
    Psilocybin: The most effective moral bio‐enhancer?Vojin Rakić - 2023 - Bioethics 37 (7):683-689.
    This paper addresses the possible effects of psychedelic drugs, notably psilocybin, on moral bio-enhancement (MBE). It will be argued that non-psychedelic substances, such as oxytocin, serotonin/serotonin reuptake inhibitors, or vasopressin, have indirect effects on M(B)E, whereas psilocybin has direct effects. Additionally, morality and happiness have been shown to operate in a circularly supportive relationship. It will be argued that psilocybin also has more direct effects on the augmentation of human happiness than non-psychedelic substances. Hence, psilocybin multiplies (...)
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  2.  29
    Opening Death’s Door: Psilocybin and Existential Suffering in Palliative Care.Duff R. Waring - 2022 - In Tomas Zima & David N. Weisstub (eds.), Medical Research Ethics: Challenges in the 21st Century. Springer Verlag. pp. 235-262.
    A signal challenge of twenty-first century psychiatry is the effective treatment of existential/spiritual suffering in palliative care. This chapter will concentrate on research to assess the therapeutic potential of psilocybin to assuage that suffering. If a “psychedelic experience” can facilitate an acceptance of impending death, and reduce the existential suffering of those who endure it, it could prove to be a valuable intervention where one is sorely needed. The therapeutic use of psilocybin with dying patients (hereinafter patients) raises (...)
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  3.  5
    Psilocybin, moralization and psychotherapy: a scoping review and a case report.Emiliano Loria, Elisabetta Lalumera & Ambra D’Imperio - forthcoming - Philosophical Psychology.
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  4.  33
    Psilocybin and the Meaning Response: Exploring the Healing Process in a Retreat Setting in Jamaica.Maria Orozco & Shana Harris - 2023 - Anthropology of Consciousness 34 (1):130-160.
    In the past decade, the consumption of psilocybin mushrooms has become a popular therapeutic tool for people looking to deal with mental and emotional health issues. The emerging interest in psilocybin therapy in the global north has led to the development of retreat centers in locations where psilocybin is legal or unregulated. Drawing on ethnographic research at a psilocybin retreat center in Jamaica, this article examines the emotional and somatic reactions attributed to psilocybin that influence (...)
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  5.  15
    Psilocybin-Assisted Compassion Focused Therapy for Depression.Wendy Pots & Farid Chakhssi - 2022 - Frontiers in Psychology 13.
    Psilocybin-assisted psychotherapy, i.e., psilocybin treatment with psychological support, has demonstrated the efficacy of psilocybin to reduce depressive symptoms. However, in clinical trials, the structure of psilocybin-assisted psychotherapy is primarily based on preparation, navigation, and integration. For psychotherapeutic guidance, the application of this structure is favored over the usage of theoretical models. The applied psychotherapeutic models may be of critical importance if the effects are augmented due to the psychologically insightful experiences during the navigation and integration sessions. (...)
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  6. Psilocybin, LSD, Mescaline and drug-induced synesthesia.Dimitria Electra Gatzia & Berit Brogaard - 2016 - In Victor R. Preedy (ed.), The Neuropathology Of Drug Addictions And Substance Misuse. Elsevier.
    Studies have shown that both serotonin and glutamate receptor systems play a crucial role in the mechanisms underlying drug-induced synesthesia. The specific nature of these mechanisms, however, continues to remain elusive. Here we propose two distinct hypotheses for how synesthesia triggered by hallucinogens in the serotonin-agonist family may occur. One hypothesis is that the drug-induced destabilization of thalamic projections via GABAergic neuronal circuits from sensory areas leads to a disruption of low-level, spontaneous integration of multisensory stimuli. This sort of integration (...)
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  7.  69
    (1 other version)The Phenomenology and Potential Religious Import of States of Consciousness Facilitated by Psilocybin.William A. Richards - 2008 - Archive for the Psychology of Religion 30 (1):189-199.
    Accompanying the resumption of human research with the entheogen , psilocybin, the range of states of consciousness reported during its action, including both nonmystical and mystical forms of experience, is surveyed and defined. The science and art of facilitating mystical experiences is discussed on the basis of research experience. The potential religious import of these states of consciousness is noted in terms of recognizing the reality of the spiritual, in better understanding the biochemistry of revelation, and in exploring the (...)
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  8.  4
    Salience, sensemaking, and setting in psilocybin microdosing: Methodological lessons and preliminary findings of a mixed method qualitative study.Aleš Oblak, Liam Korošec Hudnik, Anja Levačić, Kristian Elersič, Peter Pregelj & Jurij Bon - forthcoming - Philosophical Psychology.
    There are profound methodological challenges facing microdosing research. One way we can address some of these methodological issues is by understanding how psilocybin microdosing fits in the broader existential context of people’s lives. We recruited participants who underwent psilocybin microdosing on their own and consented to being monitored for harm mitigation purposes. We combined momentary ecological assessment and detailed retrospective interviews. Participants reported loosening of mental structures (i.e., less intense strength of thoughts, tangential stream of consciousness), increased salience (...)
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  9.  52
    Experiences With Sacred Mushrooms and Psilocybin In Dialogue: Transdisciplinary Interpretations Of The “Velada”.Antonella Fagetti & Roberto E. Mercadillo - 2022 - Anthropology of Consciousness 33 (2):385-411.
    We present the set and setting of the velada, the Mazatec ritual of divination and healing. We highlight the subjective experiences of individuals who consumed sacred mushrooms and interpret them from their cultural and community contexts, but also from findings derived from experimental and neuroscientific research. We understand that the experiences connected to sacred mushrooms can be explained by the effects of psilocybin on the neurobiology of emotions, decision making, and visual, auditory, and bodily imagery. But we also understand (...)
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  10.  54
    Insights for Modern Applications of Psilocybin Therapy from a Case Study of Traditional Mazatec Medicine.Jesús M. González-Mariscal & Paulina E. Sosa-Cortés - 2022 - Anthropology of Consciousness 33 (2):358-384.
    The "people of knowledge" of traditional Mazatec medicine have preserved until today the ritual use of psilocybin mushrooms as part of their health care systems. The renewed interest in the effect of psilocybin on human consciousness for both therapeutic and recreational purposes usually obviates the historical and cultural background of indigenous peoples, as well as the legitimation of their practices and knowledge. In this article, through the case study of a foreign person who attended a Mazatec ritual specialist (...)
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  11.  31
    Strong Bipartisan Support for Controlled Psilocybin Use as Treatment or Enhancement in a Representative Sample of US Americans: Need for Caution in Public Policy Persists.Julian D. Sandbrink, Kyle Johnson, Maureen Gill, David B. Yaden, Julian Savulescu, Ivar R. Hannikainen & Brian D. Earp - 2024 - American Journal of Bioethics Neuroscience 15 (2):82-89.
    The psychedelic psilocybin has shown promise both as treatment for psychiatric conditions and as a means of improving well-being in healthy individuals. In some jurisdictions (e.g., Oregon, USA), psilocybin use for both purposes is or will soon be allowed and yet, public attitudes toward this shift are understudied. We asked a nationally representative sample of 795 US Americans to evaluate the moral status of psilocybin use in an appropriately licensed setting for either treatment of a psychiatric condition (...)
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  12.  72
    Ethics and ego dissolution: the case of psilocybin.William R. Smith & Dominic Sisti - 2021 - Journal of Medical Ethics 47 (12):807-814.
    Despite the fact that psychedelics were proscribed from medical research half a century ago, recent, early-phase trials on psychedelics have suggested that they bring novel benefits to patients in the treatment of several mental and substance use disorders. When beneficial, the psychedelic experience is characterized by features unlike those of other psychiatric and medical treatments. These include senses of losing self-importance, ineffable knowledge, feelings of unity and connection with others and encountering ‘deep’ reality or God. In addition to symptom relief, (...)
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  13.  34
    Commentary: Effects of psilocybin on time perception and temporal control of behavior in humans.Katarina L. Shebloski & James M. Broadway - 2016 - Frontiers in Psychology 7.
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  14.  28
    Intensity of Mystical Experiences Occasioned by 5-MeO-DMT and Comparison With a Prior Psilocybin Study.Joseph Barsuglia, Alan K. Davis, Robert Palmer, Rafael Lancelotta, Austin-Marley Windham-Herman, Kristel Peterson, Martin Polanco, Robert Grant & Roland R. Griffiths - 2018 - Frontiers in Psychology 9.
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  15.  14
    More Realistic Forecasting of Future Life Events After Psilocybin for Treatment-Resistant Depression.Taylor Lyons & Robin Lester Carhart-Harris - 2018 - Frontiers in Psychology 9.
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  16.  97
    Entheogens, mysticism, and neuroscience.Ron Cole-Turner - 2014 - Zygon 49 (3):642-651.
    Entheogens or psychedelic drugs such as lysergic acid diethylamide (LSD) and psilocybin are associated with mystical states of experience. Drug laws currently limit research, but important new work is under way at major biomedical research facilities showing that entheogens reliably occasion mystical experiences and thereby allow research into brain states during these experiences. Are drug-occasioned mystical experiences neurologically the same as more traditional mystical states? Are there phenomenological and theological differences? As this research goes forward and the public becomes (...)
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  17. Naturalizing psychedelic spirituality.Chris Letheby - 2017 - Zygon 52 (3):623-642.
    A pressing philosophical problem is how to respond to the existential, anxiety and disenchantment resulting from a naturalistic worldview that eschews transcendent foundations for meaning and value. This problem is becoming more urgent as the popularization of neuroscientific findings renders a disenchanted conception of human beings ever more vivid, compelling, and widespread. I argue that the study of transformative experiences occasioned by classic psychedelic drugs such as lysergic acid diethylamide and psilocybin may reveal the nature of a viable practical (...)
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  18. Philosophy of Psychedelics.Chris Letheby - 2021 - Oxford, UK: Oxford University Press.
    Recent clinical trials show that psychedelics such as LSD and psilocybin can be given safely in controlled conditions, and can cause lasting psychological benefits with one or two administrations. Supervised psychedelic sessions can reduce symptoms of anxiety, depression, and addiction, and improve well-being in healthy volunteers, for months or even years. But these benefits seem to be mediated by "mystical" experiences of cosmic consciousness, which prompts a philosophical concern: do psychedelics cause psychological benefits by inducing false or implausible beliefs (...)
  19. Psychedelics: A Window into Perceptual Processing.Dimitria Gatzia Electra & Berit Brogaard - 2024 - In Chris Letheby & Philip Gerrans (eds.), Philosophical Perspectives on Psychedelic Psychiatry. Oxford University Press.
    In this chapter, we first present findings indicating that psilocybin-induced visual distortions and impaired executive functioning originate in temporary disruptions of bottom-up and top-down attentional mechanisms. We then revisit a recent predictive processing account of psychedelic experiences and argue that it lacks the resources to provide an adequate account of psychedelic experiences. Lastly, we propose an alternative theory of perceptual processing that can explain how the psilocybin-induced disruptions of attentional mechanisms may elicit psychedelic experiences.
     
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  20. Naturalistic Entheogenics.Chris Letheby - 2022 - Philosophy and the Mind Sciences 3.
    In this précis I summarise the main ideas of my book Philosophy of Psychedelics. The book discusses philosophical issues arising from the therapeutic use of “classic” psychedelic drugs such as psilocybin and LSD. The book is organised around what I call the Comforting Delusion Objection to psychedelic therapy: the concern that this novel and promising treatment relies essentially on the induction of non-naturalistic metaphysical beliefs, rendering it epistemically objectionable. I begin the précis by summarizing material from chapters two and (...)
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  21.  21
    Virtual Reality as a Moderator of Psychedelic-Assisted Psychotherapy.Agnieszka D. Sekula, Luke Downey & Prashanth Puspanathan - 2022 - Frontiers in Psychology 13:813746.
    Psychotherapy with the use of psychedelic substances, including psilocybin, lysergic acid diethylamide (LSD), ketamine, and 3,4-methylenedioxymethamphetamine (MDMA), has demonstrated promise in treatment of post-traumatic stress disorder (PTSD), anxiety, addiction, and treatment-resistant depression. Psychedelic-assisted psychotherapy (PP) represents a unique psychopharmacological model that leverages the profound effects of the psychedelic experience. That experience is characterized by strong dependency on two key factors: participant mindset and the therapeutic environment. As such, therapeutic models that utilize psychedelics reflect the need for careful design that (...)
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  22.  28
    Valuing the Acute Subjective Experience.Katherine Cheung, Brian D. Earp & David B. Yaden - 2024 - Perspectives in Biology and Medicine 67 (1):155-165.
    ABSTRACT:Psychedelics, including psilocybin, and other consciousness-altering compounds such as 3,4-methylenedioxymethamphetamine (MDMA), currently are being scientifically investigated for their potential therapeutic uses, with a primary focus on measurable outcomes: for example, alleviation of symptoms or increases in self-reported well-being. Accordingly, much recent discussion about the possible value of these substances has turned on estimates of the magnitude and duration of persisting positive effects in comparison to harms. However, many have described the value of a psychedelic experience with little or no (...)
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  23.  51
    Dissolving the self.George Deane - 2020 - Philosophy and the Mind Sciences 1 (I):1-27.
    Psychedelic drugs such as psilocybin, LSD and DMT are known to induce powerful alterations in phenomenology. Perhaps of most philosophical and scientific interest is their capacity to disrupt and even “dissolve” one of the most primary features of normal experience: that of being a self. Such “peak” or “mystical” experiences are of increasing interest for their potentially transformative therapeutic value. While empirical research is underway, a theoretical conception of the mechanisms underpinning these experiences remains elusive. In the following paper, (...)
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  24.  43
    Psychedelics, Meaningfulness, and the “Proper Scope” of Medicine: Continuing the Conversation.Katherine Cheung, Kyle Patch, Brian D. Earp & David B. Yaden - 2024 - Cambridge Quarterly of Healthcare Ethics 33 (4):601-607.
    Psychedelics such as psilocybin reliably produce significantly altered states of consciousness with a variety of subjectively experienced effects. These include certain changes to perception, cognition, and affect,1 which we refer to here as the acute subjective effects of psychedelics. In recent years, psychedelics such as psilocybin have also shown considerable promise as therapeutic agents when combined with talk therapy, for example, in the treatment of major depression or substance use disorder.2 However, it is currently unclear whether the aforementioned (...)
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  25. Moral Transhumanism: The Next Step.M. N. Tennison - 2012 - Journal of Medicine and Philosophy 37 (4):405-416.
    Although transhumanism offers hope for the transcendence of human biological limitations, it generates many intrinsic and consequential ethical concerns. The latter include issues such as the exacerbation of social inequalities and the exponentially increasing technological capacity to cause harm. To mitigate these risks, many thinkers have initiated investigations into the possibility of moral enhancement that could limit the power disparities facilitated by biotechnological enhancement. The arguments often focus on whether moral enhancement is morally permissible, or even obligatory, and remain largely (...)
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  26. Psychedelics, Meditation, and Self-Consciousness.Raphaël Millière, Robin L. Carhart-Harris, Leor Roseman, Fynn-Mathis Trautwein & Aviva Berkovich-Ohana - 2018 - Frontiers in Psychology 9:375105.
    In recent years, the scientific study of meditation and psychedelic drugs has seen remarkable developments. The increased focus on meditation in cognitive neuroscience has led to a cross-cultural classification of standard meditation styles validated by functional and structural neuroanatomical data. Meanwhile, the renaissance of psychedelic research has shed light on the neurophysiology of altered states of consciousness induced by classical psychedelics, such as psilocybin and LSD, whose effects are mainly mediated by agonism of serotonin receptors. Few attempts have been (...)
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  27.  77
    Healing with Plant Intelligence: A Report from Ayahuasca.Richard Doyle - 2012 - Anthropology of Consciousness 23 (1):28-43.
    Numerous and diverse reports indicate the efficacy of shamanic plant adjuncts (e.g., iboga, ayahuasca, psilocybin) for the care and treatment of addiction, post-traumatic stress disorder, cancer, cluster headaches, and depression. This article reports on a first-person healing of lifelong asthma and atopic dermatitis in the shamanic context of the contemporary Peruvian Amazon and the sometimes digital ontology of online communities. The article suggests that emerging language, concepts, and data drawn from the sciences of plant signaling and behavior regarding “plant (...)
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  28.  71
    Psychedelic Identity Shift: A Critical Approach to Set And Setting.Neşe Devenot, Aidan Seale-Feldman, Elyse Smith, Tehseen Noorani, Albert Garcia-Romeu & Matthew W. Johnson - 2022 - Kennedy Institute of Ethics Journal 32 (4):359-399.
    ABSTRACT:While the literature on psychedelic medicine emphasizes the importance of set and setting alongside the quality of subjective drug effects for therapeutic efficacy, few scholars have explored the therapeutic frameworks that are used alongside psychedelics in the lab or in the clinic. Based on a narrative analysis of the treatment manual and post-session experience reports from a pilot study of psilocybin-assisted treatment for tobacco smoking cessation, this article examines how therapeutic frameworks interact with the psychedelic substance in ways that (...)
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  29.  58
    Past Is Prologue: Ethical Issues in Pediatric Psychedelics Research and Treatment.Gail A. Edelsohn & Dominic Sisti - 2023 - Perspectives in Biology and Medicine 66 (1):129-144.
    Abstractabstract:Recent clinical trials of psychedelic drugs aim to treat a range of psychiatric conditions in adults. MDMA and psilocybin administered with psychotherapy have received FDA designation as "breakthrough therapies" for post-traumatic stress disorder (PTSD) and treatment-resistant depression (TRD) respectively. Given the potential benefit for minors burdened with many of the same disorders, calls to expand experimentation to minors are inevitable. This essay examines psychedelic research conducted on children from 1959 to 1974, highlighting methodological and ethical flaws. It provides ethics (...)
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  30.  33
    Songs of Life: Psychedelic-Assisted Psychotherapy and Deleuze and Guattari’s ‘Desiring-Production’.Patricia Kubala - 2023 - Deleuze and Guattari Studies 17 (4):482-505.
    This paper argues that practitioners of psychedelic-assisted therapy could learn a great deal from Deleuze and Guattari’s critique of psychoanalysis in Anti-Oedipus, as well as the practice of materialist psychiatry – schizoanalysis – that they offer in its stead. Much of the clinical research on psychedelics (particularly psilocybin) over the past fifteen years has privileged mystical experience, assessed according to a quantifiable scale, as the goal of psychedelic-assisted psychotherapy and source of cure ( Griffiths et al. 2006, 2016 ; (...)
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  31.  69
    Mad Thoughts on Mushrooms: Discourse and Power in the Study of Psychedelic Consciousness.Andy Letcher - 2007 - Anthropology of Consciousness 18 (2):74-98.
    This paper addresses the question of what happens to consciousness under the influence of psychedelic drugs—specifically of psilocybin, or “magic” mushrooms— and performs a Foucauldian discourse analysis upon the answers that have been variously proposed. Predominant societally legitimated answers (the pathological, psychological, and prohibition discourses) are those that, in Foucault's sense, are imposed from the outside as “scientific classifications,” that is, they are based upon observations of the effects of mushrooms on others. By contrast, a series of resistive discourses (...)
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  32.  12
    Death risk: Lack of movement: The ignored pandemic of digitalization escalates the COVID-19 crisis.Lucas Pawlik - 2021 - Technoetic Arts 19 (1):139-152.
    Data analysis from diverse medical fields suggests that we have reached a tipping point in the digitalization dynamic through the ongoing COVID-19 crisis, leading to an escalation of physical inactivity and related diseases. The lack of prioritization of physical activity designed to intervene against obesity, diabetes, loneliness, depression, anxiety disorders and suicide risk could destabilize our current global health system beyond rehabilitation. To counteract this, the author outlines the basis for a sustainable solution to best integrate physical activity into work, (...)
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  33. Psychedelics, Mysticism and Morality.Ralph J. Tapia - 1970 - Thought: Fordham University Quarterly 45 (2):235-252.
    A theologian answers the question: What is the relationship between the hallucinogenic drugs, such as hashish, marihuana, mescaline, psilocybin, LSD, and both mysticism and morality?
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  34.  70
    Compassionate use of psychedelics.Martin Šurkala & Adam Greif - 2020 - Medicine, Health Care and Philosophy 23 (3):485-496.
    In the present paper, we discuss the ethics of compassionate psychedelic psychotherapy and argue that it can be morally permissible. When talking about psychedelics, we mean specifically two substances: psilocybin and MDMA. When administered under supportive conditions and in conjunction with psychotherapy, therapies assisted by these substances show promising results. However, given the publicly controversial nature of psychedelics, compassionate psychedelic psychotherapy calls for ethical justification. We thus review the safety and efficacy of psilocybin- and MDMA-assisted therapies and claim (...)
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  35. Sacred plants and visionary consciousness.José Luis Díaz - 2010 - Phenomenology and the Cognitive Sciences 9 (2):159-170.
    Botanical preparations used by shamans in rituals for divination, prophecy, and ecstasy contain widely different psychoactive compounds, which are incorrectly classified under a single denomination such as “hallucinogens,” “psychedelics,” or “entheogens.” Based on extensive ethnopharmacological search, I proposed a psychopharmacological classification of magic plants in 1979. This paper re-evaluates this taxonomy in the context of consciousness research. Several groups of psychodysleptic magic plants are proposed: (1) hallucinogens—psilocybin mushrooms, mescaline cacti, dimethyltryptamine snuffs, and the synthetic ergoline lysergic acid diethylamide induce (...)
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  36.  20
    Consenting to consent.Zoë Fritz - 2021 - Journal of Medical Ethics 47 (12):777-778.
    Both ethicists and lawyers accept that a provider – be it a researcher or a clinician – should provide sufficient information for a reasonable person to make an informed decision about whether they wish to go ahead with the proposed intervention or treatment.1 They are bound to do so both because they have an ethical responsibility to preserve the individual’s autonomous decision making, and, in many countries, because the law obliges them to. In this month’s issue of the JME, three (...)
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  37.  14
    Introduction to the Special Section on Psychedelics Research and Treatment.Dominic Sisti - 2024 - Perspectives in Biology and Medicine 67 (1):114-116.
    In lieu of an abstract, here is a brief excerpt of the content:Introduction to the Special Section on Psychedelics Research and TreatmentDominic SistiAgainst a backdrop of post-pandemic malaise, diseases of despair, and a fragmented mental health care system, psychedelics have enjoyed a resurgence of interest as powerful psychotherapeutic agents and as catalysts of personal growth. The true power of these substances—some of which are considered sacramental by Indigenous peoples—has been shrouded for half a century by cultural mythology, political propaganda, and (...)
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  38.  20
    Is the Requirement for First-Person Experience of Psychedelic Drugs a Justified Component of a Psychedelic Therapist’s Training?Nathan Emmerich & Bryce Humphries - 2024 - Cambridge Quarterly of Healthcare Ethics 33 (4):548-557.
    Recent research offers good reason to think that various psychedelic drugs—including psilocybin, ayahuasca, ketamine, MDMA, and LSD—may have significant therapeutic potential in the treatment of various mental health conditions, including post-traumatic stress disorder, depression, existential distress, and addiction. Although the use of psychoactive drugs, such as Diazepam or Ritalin, is well established, psychedelics arguably represent a therapeutic step change. As experiential therapies, their value would seem to lie in the subjective experiences they induce. As it is the only way (...)
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  39.  56
    Dark Side of the Shroom: Erasing Indigenous and Counterculture Wisdoms with Psychedelic Capitalism, and the Open Source Alternative.Neşe Devenot, Trey Conner & Richard Doyle - 2022 - Anthropology of Consciousness 33 (2):476-505.
    Psychedelic or ecodelic medicines (e.g., psilocybin, ayahuasca, iboga) for the care and treatment of addiction, post‐traumatic stress disorder, cancer, cluster headaches, anxiety, and depression have surged to the forefront of discussions about mental health in the US, leading to the emergence of well‐capitalized biotech companies offering multimillion‐dollar IPOs. Venture capital website Pitchbook reports “continuing investor interest and growing acceptance of what until recently was seen as a fringe area of medicine.” As scholars, activists, and practitioners who have been healed (...)
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  40.  56
    Psychedelic-assisted psychotherapy for the treatment of major depression: a synthesis of phenomenological explanations.Riccardo Miceli McMillan & Christopher Jordens - 2022 - Medicine, Health Care and Philosophy 25 (2):225-237.
    Psychedelic-assisted Psychotherapy combines the use of psychedelic compounds, such as psilocybin, with psychotherapy. PAP has shown some promise as a novel treatment for Major Depressive Disorder, and empirical research suggests that its efficacy turns on the altered states induced by psychedelic compounds. In this paper we draw on the literature of phenomenology to explain the therapeutic potential of psychedelic experiences. Svenaeus characterises mental illness as a form of suffering that entails three distinct but related experiences of alienation or “unhomelike (...)
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  41. Entheogens in Christian Art: Wasson, Allegro and the Psychedelic Gospels.Jerry Brown & Julie M. Brown - 2019 - Journal of Psychedelic Studies 3 (2):142-163.
    In light of new historical evidence regarding ethnomycologist R. Gordon Wasson’s correspondence with art historian Erwin Panofsky, this article provides an in-depth analysis of the presence of entheogenic mushroom images in Christian art within the context of the controversy between Wasson and philologist John Marco Allegro over the identification of a Garden of Eden fresco in the 12th century Chapel of Plaincourault in France. It reveals a compelling financial motive for Wasson’s refusal to acknowledge that this fresco represents Amanita muscaria, (...)
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  42. Psychedelic Expansion of Consciousness: A Phenomenological Study in Terms of Attention.Jason K. Day & Susanne Schmetkamp - 2022 - InCircolo 13:111-135.
    Induced by intake of the psychedelic substances LSD, psilocybin, DMT and mescaline, psychedelic experiences have been extensively described by subjects as entailing a most unusual increase in the scope and quality of their consciousness. Accordingly, psychedelic experiences have been widely characterised as an “expansion of consciousness.” This article poses the following question, as yet unaddressed in contemporary philosophy and the tradition of phenomenology: to what exactly does “expansion of consciousness” refer as a general characterisation of psychedelic experiences, and what (...)
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  43.  10
    A Comparative Model of Mysticism: Cognitive Neuroscience, Phenomenal Experiences, and Noetic Accounts.Hemal P. Trivedi - forthcoming - Archive for the Psychology of Religion.
    This article proposes a model of comparative mysticism that bases its rationale for comparison in the dynamic interaction between three components: neurocognitive mechanisms and substrates, phenomenal experiences, and noetic accounts. In examining the phenomenon of ego- dissolution ( EDn), using this model, a scholar can identify universal and contextual components of a mystic’s experiences. The neurocognitive component is derived from neuroscientific studies including brain injury, psychedelics, and meditative practices. The phenomenal and noetic components are derived from personal accounts as narrated (...)
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  44.  16
    Ethical considerations for psychedelic-assisted therapy in military clinical settings.Scott Hoener, Aaron Wolfgang, David Nissan & Edmund Howe - 2024 - Journal of Medical Ethics 50 (4):258-262.
    Psychedelic treatments, particularly 3,4-methylenedioxymethamphetamine (MDMA)-assisted and psilocybin-assisted therapies, have recently seen renewed interest in their clinical potential to treat various mental health conditions. Clinical trials for both MDMA-assisted and psilocybin-assisted therapies have shown to be highly efficacious for post-traumatic stress disorder and major depression. Recent research trials for psychedelic-assisted therapies (PAT) have demonstrated that although they are resource-intensive, their effects are rapid-acting, durable and cost-effective. These results have generated enthusiasm among researchers seeking to investigate psychedelic therapies in active-duty (...)
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  45. The epistemic innocence of psychedelic states.Chris Letheby - 2016 - Consciousness and Cognition 39:28-37.
    One recent development in epistemology, the philosophical study of knowledge, is the notion of ‘epistemic innocence’ introduced by Bortolotti and colleagues. This concept expresses the idea that certain suboptimal cognitive processes may nonetheless have epistemic (knowledge-related) benefits. The idea that delusion or confabulation may have psychological benefits is familiar enough. What is novel and interesting is the idea that such conditions may also yield significant and otherwise unavailable epistemic benefits. I apply the notion of epistemic innocence to research on the (...)
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  46. Self unbound: ego dissolution in psychedelic experience.Chris Letheby & Philip Gerrans - 2017 - Neuroscience of Consciousness 3:1-11.
    Users of psychedelic drugs often report that their sense of being a self or ‘I’ distinct from the rest of the world has diminished or altogether dissolved. Neuroscientific study of such ‘ego dissolution’ experiences offers a window onto the nature of self-awareness. We argue that ego dissolution is best explained by an account that explains self-awareness as resulting from the integrated functioning of hierarchical predictive models which posit the existence of a stable and unchanging entity to which representations are bound. (...)
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  47. Here and now: Discovering the sacred with entheogens.William A. Richards - 2014 - Zygon 49 (3):652-665.
    Renewed research with entheogens (psychedelic substances) has been able to facilitate the occurrence of mystical forms of consciousness in healthy volunteers with a high degree of reliability. This article explores the potential significance of this development for religious scholars, especially those interested in the study of mysticism. The definition of “mystical consciousness” employed in this research is presented and differentiated from visionary/archetypal and other types of alternative mental states. The ways in which entheogens may be employed with skill and maximum (...)
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  48.  83
    A systems model of altered consciousness: Integrating natural and drug-induced psychoses.Franz X. Vollenweider & Mark A. Geyer - 2001 - Brain Research Bulletin. Special Issue 56 (5):495-507.
  49. Psychedelic therapy for body dysmorphic disorder.Shevaugn Johnson & Chris Letheby - 2022 - Journal of Psychedelic Studies 6 (1):23-30.
    In this opinion piece we propose the investigation of psychedelic-assisted psychotherapy for the treatment of body dysmorphic disorder (BDD). BDD is a psychiatric disorder characterised by appearance-based preoccupations and accompanying compulsions. While safe and effective treatments for BDD exist, non-response and relapse rates remain high. Therefore, there is a need to investigate promising new treatment options for this highly debilitating condition. Preliminary evidence suggests safety, feasibility, and potential efficacy of psychedelic treatments in disorders that share similar psychopathological mechanisms with BDD. (...)
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  50. The Philosophy of Psychedelic Transformation.Chris Letheby - 2015 - Journal of Consciousness Studies 22 (9-10):170-193.
    Recent scientific research into the therapeutic potential and mechanisms of psychedelic drugs raises intriguing and hitherto largely unexplored philosophical questions. A brief overview of the relevant science is given before addressing these questions. It is argued that psychedelic transformation is a distinctive psycho- pharmacological intervention because its mechanism of action ineliminably involves conscious mental representations, and thus is more transparent to the subject than the mechanisms of other drug therapies. This argument connects with issues in the philosophy of (cognitive) scientific (...)
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