This article aims to achieve two goals: to show that probability is not the only way of dealing with uncertainty ; and to provide evidence that logic-based methods can well support reasoning with uncertainty. For the latter claim, two paradigmatic examples are presented: logic programming with Kleene semantics for modelling reasoning from information in a discourse, to an interpretation of the state of affairs of the intended model, and a neural-symbolic implementation of input/output logic for dealing with (...) class='Hi'>uncertainty in dynamic normative contexts. (shrink)

When the likelihood ratio approach is employed for evidential reasoning in law, it is often necessary to employ subjective probabilities, which are probabilities derived from the opinions and judgement of a human. At least three concerns arise from the use of subjective probabilities in legal applications. Firstly, human beliefs concerning probabilities can be vague, ambiguous and inaccurate. Secondly, the impact of this vagueness, ambiguity and inaccuracy on the outcome of a probabilistic analysis is not necessarily fully understood. Thirdly, the (...) provenance of subjective probabilities and the associated potential sources of vagueness, ambiguity and inaccuracy tend to be poorly understood, making it difficult for the outcome of probabilistic reasoning to be explained and validated, which is crucial in legal applications. The former two concerns have been addressed by a wide body of research in AI. The latter, however, has received little attention. This paper presents a novel approach to employ argumentation to reason about probability distributions in probabilistic models. It introduces a range of argumentation schemes and corresponding sets of critical questions for the construction and validation of argument models that define sets of probability distributions. By means of an extended example, the paper demonstrates how the approach, argumentation schemes and critical questions can be employed for the development of models and their validation in legal applications of the likelihood ratio approach to evidential reasoning. (shrink)

This article aims to achieve two goals: to show that probability is not the only way of dealing with uncertainty ; and to provide evidence that logic-based methods can well support reasoning with uncertainty. For the latter claim, two paradigmatic examples are presented: logic programming with Kleene semantics for modelling reasoning from information in a discourse, to an interpretation of the state of affairs of the intended model, and a neural-symbolic implementation of input/output logic for dealing with (...) class='Hi'>uncertainty in dynamic normative contexts. (shrink)

Uncertainty in Post-Reformation Catholicism provides a historical account of early modern probabilism and its theological, intellectual, and cultural implications. First developed in the second half of the sixteenth century, probabilism represented a significant and controversial novelty in Catholic moral theology. By the second half of the seventeenth century, probabilism became and has since been associated with moral, intellectual, and cultural decadence. Stefania Tutino challenges this understanding and claims that probabilism played a central role in addressing the challenges that geographical (...) and cultural expansions posed to traditional Catholic theology. Tutino argues that early modern theologians used probabilism to integrate major changes within the post-Reformation Catholic theological and intellectual system. Probabilist theologians realized that their time was characterized by many changes that traditional theology was not equipped to deal with, which consequently provoked an exponential growth of uncertainties, doubts, and dilemmas of conscience. Probabilism represented the result of their efforts to appreciate, come to terms with, and manage that uncertainty. Uncertainty in Post-Reformation Catholicism reinterprets probabilism as a way of dealing with moral and epistemological doubts in quickly changing times, a way that still may be useful today. Uncertainty in Post-Reformation Catholicism argues that probabilism played a central role in addressing the challenges that a geographically and intellectually expanding world posed to traditional Catholic theology. Early modern probabilist theologians realized that their time was characterized by many changes and novelties that traditional theology was not equipped to deal with, and that consequently provoked an exponential growth of uncertainties, doubts, and dilemmas of conscience. These theologians used probabilism as a means to integrate changes and novelties within the post-Reformation Catholic theological and intellectual system. Seen in this light, probabilism represented the result of their attempts to appreciate, come to terms with, and manage uncertainty. The problem of uncertainty was not only crucial then, but remains central even today. Despite the unprecedented amount of information available to us, we are becoming less able to formulate arguments based on facts, and more dependent on a cacophony of opinions that often simply reproduce our own implicit or explicit biases, prejudices, and preconceived preferences. (shrink)

The postwar welfare state provides social insurance against economic, health, and related risks in an uncertain world. Because everyone can envision themselves to be among the unfortunate, social insurance fuses self-interest and solidarism in a normative principle Friedman (2020) calls probabilistic justice. But there is a competing principle of status defense, where the aim is to erect boundaries between socioeconomic strata and discourage cross-class mobility. We argue that this principle dominates when inequality is high and uncertainty low. The (...) current moment is one of high inequality and high uncertainty, which results in intense status anxiety, yet does not rule out solidaristic solutions. Our contributions are to diagnose the causes of our current malaise, and to theorize the normative bases for the political choice facing contemporary western democracies. (shrink)

The aim of this paper is to examine whether it would be advantageous to introduce knowledge norms instead of the currently assumed rational credence norms into the debate about decision making under normative uncertainty. There is reason to think that this could help us better accommodate cases in which agents are rationally highly confident in false moral views. I show how Moss’ view of probabilistic knowledge can be fruitfully employed to develop a decision theory that delivers plausible verdicts (...) in these cases. I also argue that, for this new view to be better than existing alternatives, it must adopt a particular solution to the new evil demon problem, which asks whether agents and their BIV-counterparts are equally justified. In order to get an attractive decision theory for cases of moral uncertainty, we must reject the claim that agents and their BIV-counterparts are equally justified. Moreover, the resulting view must be supplemented with a moral epistemology that explains how it is possible to be rationally morally uncertain. This is especially challenging if we assume that moral truths are knowable a priori. (shrink)

This paper presents a general-purpose update semantics for expressions of subjective uncertainty in natural language. First, a set of desiderata are established for how expressions of subjective uncertainty should behave in dynamic, update-based semantic systems; then extant implementations of expressions of subjective uncertainty in such models are evaluated and found wanting; finally, a new update semantics is proposed. The desiderata at the heart of this paper center around the contention that expressions of subjective uncertainty express beliefs (...) which are not persistent, whereas propositions express beliefs that are persistent. I argue that if we make the move of treating updates in a dynamic semantics as Bayesian updates, i.e. as conditionalization, then expressions of subjective uncertainty will behave the way we want them to without altering the way propositions behave. (shrink)

I argue that in order to account for normative uncertainty, an expressivist theory of normative language and thought must accomplish two things: Firstly, it needs to find room in its framework for a gradable conative attitude, degrees of which can be interpreted as representing normative uncertainty. Secondly, it needs to defend appropriate rationality constraints pertaining to those graded attitudes. The first task – finding an appropriate graded attitude that can represent uncertainty – is not particularly problematic. I (...) tackle the second task by exploring whether we can devise expressivist versions of the standard arguments used to support rationality constraints on degrees of uncertainty, Dutch book arguments and accuracy-dominance arguments. I show that we can do so, but that the resulting arguments don’t support the same rationality constraints as the original versions of the arguments. (shrink)

Over the past decades or so the probabilistic model of rational belief has enjoyed increasing interest from researchers in epistemology and the philosophy of science. Of course, such probabilistic models were used for much longer in economics, in game theory, and in other disciplines concerned with decision making. Moreover, Carnap and co-workers used probability theory to explicate philosophical notions of confirmation and induction, thereby targeting epistemic rather than decision-theoretic aspects of rationality. However, following Carnap’s early applications, philosophy has (...) more recently seen an increased popularity of probabilistic models in other areas concerned with the philosophical analysis of belief: there are models targeting coherence, informativeness, simplicity, and so on.In brief, the probabilistic model of belief comprises of a language, detailing the propositions about which an agent is supposed to have beliefs, and a function over the language that expresses beliefs: .. (shrink)

Hilary Bowman-Smart et al. (2023) have rightly pointed out that one of the recurring criticisms of the use of noninvasive prenatal testing (NIPT) for non-medical trait prediction is the probabilist...

The environment in which humans evolved is strongly and positively autocorrelated in space and time. Probabilistic judgments based on the assumption of independence may not yield evolutionarily adaptive behavior. A number of “faults” of human reasoning are not faulty under fuzzy arithmetic, a nonprobabilistic calculus of reasoning under uncertainty that may be closer to that underlying human decision making.

In many real-life situations, we are interested in the value of a physical quantity y that is difficult or impossible to measure directly. To estimate y, we find some easier-to-measure quantities x1, … , xn which are related to y by a known relation y = f. Measurements are never 100% accurate; hence, the measured values equation image are different from xi, and the resulting estimate equation image is different from the desired value y = f. How different can it (...) be? Traditional engineering approach to error estimation in data processing assumes that we know the probabilities of different measurement errors equation image. In many practical situations, we only know the upper bound Δi for this error; hence, after the measurement, the only information that we have about xi is that it belongs to the interval equation image. In this case, it is important to find the range y of all possible values of y = f when xi ∈ xi. We start the paper with a brief overview of the computational complexity of the corresponding interval computation problems: Most of the related problems turn out to be, in general, at least NP-hard. In this paper, we show how the use of quantum computing can speed up some computations related to interval and probabilistic uncertainty. We end the paper with speculations on whether “hypothetic” physical devices can compute NP-hard problems faster than in exponential time. Most of the paper's results were first presented at NAFIPS'2003 [30]. (shrink)

Although we endorse the primacy of uncertainty in reasoning, we argue that a probabilistic framework cannot model the fundamental skill of proof administration. Furthermore, we are skeptical about the assumption that standard probability calculus is the appropriate formalism to represent human uncertainty. There are other models up to this task, so let us not repeat the excesses of the past.

There is wide support in logic, philosophy, and psychology for the hypothesis that the probability of the indicative conditional of natural language, P(if A then B), is the conditional probability of B given A, P(B|A). We identify a conditional which is such that P(if A then B)=P(B|A) with de Finetti's conditional event, B|A. An objection to making this identification in the past was that it appeared unclear how to form compounds and iterations of conditional events. In this paper, we illustrate (...) how to overcome this objection with a probabilistic analysis, based on coherence, of these compounds and iterations. We interpret the compounds and iterations as conditional random quantities which, given some logical dependencies, may reduce to conditional events. We show how the inference to B|A from A and B can be extended to compounds and iterations of both conditional events and biconditional events. Moreover, we determine the respective uncertainty propagation rules. Finally, we make some comments on extending our analysis to counterfactuals. (shrink)

A probabilistic explication is offered of equipoise and uncertainty in clinical trials. In order to be useful in the justification of clinical trials, equipoise has to be interpreted in terms of overlapping probability distributions of possible treatment outcomes, rather than point estimates representing expectation values. Uncertainty about treatment outcomes is shown to be a necessary but insufficient condition for the ethical defensibility of clinical trials. Additional requirements are proposed for the nature of that uncertainty. The indecisiveness (...) of our criteria for cautious decision-making under uncertainty creates the leeway that makes clinical trials defensible. (shrink)

Should Probabilistic Design Replace Safety Factors? Content Type Journal Article Pages 151-168 DOI 10.1007/s13347-010-0003-6 Authors Neelke Doorn, Department of Technology, Policy and Management, Delft University of Technology, PO Box 5015, 2600 GA Delft, The Netherlands Sven Ove Hansson, Department of Philosophy and the History of Technology, Royal Institute of Technology, Teknikringen 78 B, 100 44 Stockholm, Sweden Journal Philosophy & Technology Online ISSN 2210-5441 Print ISSN 2210-5433 Journal Volume Volume 24 Journal Issue Volume 24, Number 2.

Probabilistic argumentation and neuro-argumentative systems offer new computational perspectives for the theory and applications of argumentation, but their principled construction involves two entangled problems. On the one hand, probabilistic argumentation aims at combining the quantitative uncertainty addressed by probability theory with the qualitative uncertainty of argumentation, but probabilistic dependences amongst arguments as well as learning are usually neglected. On the other hand, neuro-argumentative systems offer the opportunity to couple the computational advantages of learning and massive (...) parallel computation from neural networks with argumentative reasoning and explanatory abilities, but the relation of probabilistic argumentation frameworks with these systems has been ignored so far. Towards the construction of neuro-argumentative systems based on probabilistic argumentation, we associate a model of abstract argumentation and the graphical model of Boltzmann machines in order to (i... (shrink)

Two types of measures of probabilistic uncertainty are introduced and investigated. Dispersion measures report how diffused the agent’s second-order probability distribution is over the range of first-order probabilities. Robustness measures reflect the extent to which the agent’s assessment of the prior (objective) probability of an event is perturbed by information about whether or not the event actually took place. The properties of both types of measures are investigated. The most obvious type of robustness measure is shown to coincide (...) with one of the major candidates for a dispersion measure, the mean square deviation measure. (shrink)

Moss (2018) argues that rational agents are best thought of not as having degrees of belief in various propositions but as having beliefs in probabilistic contents, or probabilistic beliefs. Probabilistic contents are sets of probability functions. Probabilistic belief states, in turn, are modeled by sets of probabilistic contents, or sets of sets of probability functions. We argue that this Mossean framework is of considerable interest quite independently of its role in Moss’ account of probabilistic (...) knowledge or her semantics for epistemic modals and probability operators. It is an extremely general model of uncertainty. Indeed, it is at least as general and expressively powerful as every other current imprecise probability framework, including lower probabilities, lower previsions, sets of probabilities, sets of desirable gambles, and choice functions. In addition, we partially answer an important question that Moss leaves open, viz., why should rational agents have consistent probabilistic beliefs? We show that an important subclass of Mossean believers avoid Dutch bookability iff they have consistent probabilistic beliefs. (shrink)

Modus ponens (from A and “if A then C” infer C) is one of the most basic inference rules. The probabilistic modus ponens allows for managing uncertainty by transmitting assigned uncertainties from the premises to the conclusion (i.e., from P(A) and P(C|A) infer P(C)). In this paper, we generalize the probabilistic modus ponens by replacing A by the conditional event A|H. The resulting inference rule involves iterated conditionals (formalized by conditional random quantities) and propagates previsions from the (...) premises to the conclusion. Interestingly, the propagation rules for the lower and the upper bounds on the conclusion of the generalized probabilistic modus ponens coincide with the respective bounds on the conclusion for the (non-nested) probabilistic modus ponens. (shrink)

We investigate an approach for drawing logical inference from inconsistent premisses. The main idea in this approach is that the inconsistencies in the premisses should be interpreted as uncertainty of the information. We propose a mechanism, based on Kinght’s [14] study of inconsistency, for revising an inconsistent set of premisses to a minimally uncertain, probabilistically consistent one. We will then generalise the probabilistic entailment relation introduced in [15] for propositional languages to the first order case to draw logical (...) inference from a probabilistic set of premisses. We will show how this combination can allow us to limit the effect of uncertainty introduced by inconsistent premisses to only the reasoning on the part of the premise set that is relevant to the inconsistency. (shrink)

Normative judgments involve two gradable features. First, the judgments themselves can come in degrees; second, the strength of reasons represented in the judgments can come in degrees. Michael Smith has argued that non-cognitivism cannot accommodate both of these gradable dimensions. The degrees of a non-cognitive state can stand in for degrees of judgment, or degrees of reason strength represented in judgment, but not both. I argue that (a) there are brands of noncognitivism that can surmount Smith’s challenge, and (b) any (...) brand of non-cognitivism that has even a chance of solving the Frege–Geach Problem and some related problems involving probabilistic consistency can also thereby solve Smith’s problem. Because only versions of non-cognitivism that can solve the Frege–Geach Problem are otherwise plausible, all otherwise plausible versions of noncognitivism can meet Smith’s challenge. (shrink)

Preface to Volumes 1 and 2 Lorenz Krüger xv Introduction to Volume 1 Lorraine J. Daston 1 I Revolution 1 What Are Scientific Revolutions? Thomas S. Kuhn 7 2 Scientific Revolutions, Revolutions in Science, and a Probabilistic Revolution 1800-1930 I. Bernard Cohen 23 3 Was There a Probabilistic Revolution 1800-1930? Ian Hacking 45 II Concepts 4 The Slow Rise of Probabilism: Philosophical Arguments in the Nineteenth Century Lorenz Krüger 59 5 The Decline of the Laplacian Theory of Probability: (...) A Study of Stumpf, von Kries, and Meinong Andreas Kamlah 91 6 Fechner’s Indeterminism: From Freedom to Laws of Chance Michael Heidelberger 117 7 The Saint Petersburg Paradox 1713-1937 Gerard Jorland 157 8 Laplace and Thereafter: The Status of Probability Calculus in the Nineteenth Century Ivo Schneider 191 9 Emile Borel as a Probabilist Eberhard Knobloch 215 III Uncertainty 10 The Domestication of Risk: Mathematical Probability and Insurance 1650-1830 237 11 The Objectification of Observation: Measurement and Statistical Methods in the Nineteenth Century Zeno G. Swijtink 261 12 The Measurement of Uncertainty in Nineteenth-Century Social Science Stephen M. Stigler 287 IV Society 13 Rational Individuals versus Laws of Society: From Probability to Statistics Lorraine J. Daston 295 14 Decrire, Compter, Calculer: The Debate over Statistics during the Napoleonic Period Marie-Noelle Bourguet 305 15 Probability in Vital and Social Statistics: Quetelet, Farr, and the Bertillons Bernard-Pierre Lécuyer 317 16 Paupers and Numbers: The Statistical Argument for Social Reform in Britain during the Period of Industrialization Karl H. Metz 337 17 Lawless Society: Social Science and the Reinterpretation of Statistics in Germany, 1850-1880 Theodore M. Porter 351 18 Prussian Numbers 1860-1882 Ian Hacking 377 19 How Do Sums Count? On the Cultural Origins of Statistical Causality M. Norton Wise 395. (shrink)

Everettian accounts of quantum mechanics entail that people branch; every possible result of a measurement actually occurs, and I have one successor for each result. Is there room for probability in such an account? The prima facie answer is no; there are no ontic chances here, and no ignorance about what will happen. But since any adequate quantum mechanical theory must make probabilistic predictions, much recent philosophical labor has gone into trying to construct an account of probability for branching (...) selves. One popular strategy involves arguing that branching selves introduce a new kind of subjective uncertainty. I argue here that the variants of this strategy in the literature all fail, either because the uncertainty is spurious, or because it is in the wrong place to yield probabilistic predictions. I conclude that uncertainty cannot be the ground for probability in Everettian quantum mechanics. (shrink)

Epistemic states of uncertainty play important roles in ethical and political theorizing. Theories that appeal to a “veil of ignorance,” for example, analyze fairness or impartiality in terms of certain states of ignorance. It is important, then, to scrutinize proposed conceptions of ignorance and explore promising alternatives in such contexts. Here, I study Lerner’s probabilistic egalitarian theorem in the setting of imprecise probabilities. Lerner’s theorem assumes that a social planner tasked with distributing income to individuals in a population (...) is “completely ignorant” about which utility functions belong to which individuals. Lerner models this ignorance with a certain uniform probability distribution, and shows that, under certain further assumptions, income should be equally distributed. Much of the criticism of the relevance of Lerner’s result centers on the representation of ignorance involved. Imprecise probabilities provide a general framework for reasoning about various forms of uncertainty including, in particular, ignorance. To what extent can Lerner’s conclusion be maintained in this setting? (shrink)

Everettian accounts of quantum mechanics entail that people branch; every possible result of a measurement actually occurs, and I have one successor for each result. Is there room for probability in such an account? The prima facie answer is no; there are no ontic chances here, and no ignorance about what will happen. But since any adequate quantum mechanical theory must make probabilistic predictions, much recent philosophical labor has gone into trying to construct an account of probability for branching (...) selves. One popular strategy involves arguing that branching selves introduce a new kind of subjective uncertainty. I argue here that the variants of this strategy in the literature all fail, either because the uncertainty is spurious, or because it is in the wrong place to yield probabilistic predictions. I conclude that uncertainty cannot be the ground for probability in Everettian quantum mechanics. (shrink)

Cosmology raises novel philosophical questions regarding the use of probabilities in inference. This work aims at identifying and assessing lines of arguments and problematic principles in probabilistic reasoning in cosmology. -/- The first, second, and third papers deal with the intersection of two distinct problems: accounting for selection effects, and representing ignorance or indifference in probabilistic inferences. These two problems meet in the cosmology literature when anthropic considerations are used to predict cosmological parameters by conditionalizing the distribution of, (...) e.g., the cosmological constant on the number of observers it allows for. However, uniform probability distributions usually appealed to in such arguments are an inadequate representation of indifference, and lead to unfounded predictions. It has been argued that this inability to represent ignorance is a fundamental flaw of any inductive framework using additive measures. In the first paper, I examine how imprecise probabilities fare as an inductive framework and avoid such unwarranted inferences. In the second paper, I detail how this framework allows us to successfully avoid the conclusions of Doomsday arguments in a way no Bayesian approach that represents credal states by single credence functions could. -/- There are in the cosmology literature several kinds of arguments referring to self- locating uncertainty. In the multiverse framework, different "pocket-universes" may have different fundamental physical parameters. We don’t know if we are typical observers and if we can safely assume that the physical laws we draw from our observations hold elsewhere. The third paper examines the validity of the appeal to the "Sleeping Beauty problem" and assesses the nature and role of typicality assumptions often endorsed to handle such questions. -/- A more general issue for the use of probabilities in cosmology concerns the inadequacy of Bayesian and statistical model selection criteria in the absence of well-motivated measures for different cosmological models. The criteria for model selection commonly used tend to focus on optimizing the number of free parameters, but they can select physically implausible models. The fourth paper examines the possibility for Bayesian model selection to circumvent the lack of well-motivated priors. (shrink)

The goal of this paper is to review and critically discuss the philosophical aspects of probabilistic seismic hazard analysis (PSHA). Given that estimates of seismic hazard are typically riddled with uncertainty, diferent epistemic values (related to the pursuit of scientifc knowledge) compete in the selection of seismic hazard models, in a context infuenced by non-epistemic values (related to practical goals and aims) as well. We frst distinguish between the diferent types of uncertainty in PSHA. We claim that (...) epistemic and nonepistemic considerations are closely related in the selection of the appropriate estimate of seismic hazard by the experts. Finally, we argue that the division of scientifc responsibility among the experts can lead to responsibility gaps. This raises a problem for the ownership of the results (“no one’s model” problem) similar to the “problem of many hands” in the ethics of technology. We conclude with a plea for a close collaboration between philosophy and engineering. (shrink)

Imprecise probabilism—which holds that rational belief/credence is permissibly represented by a set of probability functions—apparently suffers from a problem known as dilation. We explore whether this problem can be avoided or mitigated by one of the following strategies: (a) modifying the rule by which the credal state is updated, (b) restricting the domain of reasonable credal states to those that preclude dilation.

Searching for information is critical in many situations. In medicine, for instance, careful choice of a diagnostic test can help narrow down the range of plausible diseases that the patient might have. In a probabilistic framework, test selection is often modeled by assuming that people's goal is to reduce uncertainty about possible states of the world. In cognitive science, psychology, and medical decision making, Shannon entropy is the most prominent and most widely used model to formalize probabilistic (...) uncertainty and the reduction thereof. However, a variety of alternative entropy metrics (Hartley, Quadratic, Tsallis, Rényi, and more) are popular in the social and the natural sciences, computer science, and philosophy of science. Particular entropy measures have been predominant in particular research areas, and it is often an open issue whether these divergences emerge from different theoretical and practical goals or are merely due to historical accident. Cutting across disciplinary boundaries, we show that several entropy and entropy reduction measures arise as special cases in a unified formalism, the Sharma–Mittal framework. Using mathematical results, computer simulations, and analyses of published behavioral data, we discuss four key questions: How do various entropy models relate to each other? What insights can be obtained by considering diverse entropy models within a unified framework? What is the psychological plausibility of different entropy models? What new questions and insights for research on human information acquisition follow? Our work provides several new pathways for theoretical and empirical research, reconciling apparently conflicting approaches and empirical findings within a comprehensive and unified information-theoretic formalism. (shrink)

A word-by-word human sentence processing complexity metric is presented. This metric formalizes the intuition that comprehenders have more trouble on words contributing larger amounts of information about the syntactic structure of the sentence as a whole. The formalization is in terms of the conditional entropy of grammatical continuations, given the words that have been heard so far. To calculate the predictions of this metric, Wilson and Carroll's (1954) original entropy reduction idea is extended to infinite languages. This is demonstrated with (...) a mildly context-sensitive language that includes relative clauses formed on a variety of grammatical relations across the Accessibility Hierarchy of Keenan and Comrie (1977). Predictions are derived that correlate significantly with repetition accuracy results obtained in a sentence-memory experiment (Keenan & Hawkins, 1987). (shrink)

When we perceive the external world, our brain has to deal with the incompleteness and uncertainty associated with sensory inputs, memory and prior knowledge. In theoretical neuroscience probabilistic approaches have received a growing interest recently, as they account for the ability to reason with incomplete knowledge and to efficiently describe perceptive and behavioral tasks. How can the probability distributions that need to be estimated in these models be represented and processed in the brain, in particular at the single (...) cell level? We consider the basic function carried out by photoreceptor cells which consists in detecting the presence or absence of light. We give a system-level understanding of the process of phototransduction based on a bayesian formalism: we show that the process of phototransduction is equivalent to a temporal probabilistic inference in a Hidden Markov Model (HMM), for estimating the presence or absence of light. Thus, the biochemical mechanisms of phototransduction underlie the estimation of the current state probability distribution of the presence of light. A classical descriptive model describes the interactions between the different molecular messengers, ions, enzymes and channel proteins occurring within the photoreceptor by a set of nonlinear coupled differential equations. In contrast, the probabilistic HMM model is described by a discrete recurrence equation. It appears that the binary HMM has a general solution in the case of constant input. This allows a detailed analysis of the dynamics of the system. The biochemical system and the HMM behave similarly under steady-state conditions. Consequently a formal equivalence can be found between the biochemical system and the HMM. Numerical simulations further extend the results to the dynamic case and to noisy input. All in all, we have derived a probabilistic model equivalent to a classical descriptive model of phototransduction, which has the additional advantage of assigning a function to phototransduction. The example of phototransduction shows how simple biochemical interactions underlie simple probabilistic inferences. (shrink)

Safety is a concern in almost all branches of engineering. Whereas safety was traditionally introduced by applying safety factors or margins to the calculated maximum load, this approach is increasingly replaced with probabilistic risk assessment (PRA) as a tool for dimensioning safety measures. In this paper, the two approaches are compared in terms of what they aim at and what they can, in fact, achieve. The outcome of this comparison suggests that the two approaches should be seen as complementary (...) rather than mutually exclusive. PRA is particularly useful for priority setting and for the effect evaluation of safety measures; however, in most applications, uncertainties prevent PRA from providing an objective probability of failure or value of damage. Safety factors are indispensible for dealing with dangers that cannot be assigned meaningful probabilities. (shrink)

You have higher-order uncertainty iff you are uncertain of what opinions you should have. I defend three claims about it. First, the higher-order evidence debate can be helpfully reframed in terms of higher-order uncertainty. The central question becomes how your first- and higher-order opinions should relate—a precise question that can be embedded within a general, tractable framework. Second, this question is nontrivial. Rational higher-order uncertainty is pervasive, and lies at the foundations of the epistemology of disagreement. Third, (...) the answer is not obvious. The Enkratic Intuition---that your first-order opinions must “line up” with your higher-order opinions---is incorrect; epistemic akrasia can be rational. If all this is right, then it leaves us without answers---but with a clear picture of the question, and a fruitful strategy for pursuing it. (shrink)

Epistemic uncertainties are included in probabilistic risk assessment (PRA) as second-order probabilities that represent the degrees of belief of the scientists that a model is correct. In this article, I propose an alternative approach that incorporates the scientist’s confidence in a probability set for a given quantity. First, I give some arguments against the use of precise probabilities to estimate scientific uncertainty in risk analysis. I then extend the “confidence approach” developed by Brian Hill and Richard Bradley to (...) PRA. Finally, I claim that this approach represents model uncertainty better than the standard (Bayesian) model does. (shrink)

A coherence-based probability semantics for categorical syllogisms of Figure I, which have transitive structures, has been proposed recently (Gilio, Pfeifer, & Sanfilippo [15]). We extend this work by studying Figure II under coherence. Camestres is an example of a Figure II syllogism: from Every P is M and No S is M infer No S is P. We interpret these sentences by suitable conditional probability assessments. Since the probabilistic inference of ~????|???? from the premise set {????|????, ~????|????} is not (...) informative, we add ????(????|(????∨????))>0 as a probabilistic constraint (i.e., an “existential import assumption”) to obtain probabilistic informativeness. We show how to propagate the assigned (precise or interval-valued) probabilities to the sequence of conditional events (????|????,~????|????,????|(????∨????)) to the conclusion ~????|???? . Thereby, we give a probabilistic meaning to the other syllogisms of Figure II. Moreover, our semantics also allows for generalizing the traditional syllogisms to new ones involving generalized quantifiers (like Most S are P) and syllogisms in terms of defaults and negated defaults. (shrink)

There is a well-documented paradigm-shift in eighteenth century Jesuit philosophy and science, at the very least in Central Europe: traditional scholastic version(s) of Aristotelianism were replaced by early modern rationalism (Wolff's systematisation of Leibnizian philosophy) and early modern science and mathematics. In the field of probability, this meant that the traditional Jesuit engagement with probability, uncertainty, and truthlikeness (in particular, as applied to moral theology) could translate into mathematical language, and can be analysed against the background of the accounts (...) of probability, pre-mathematical Jesuit logic, Wolff's conceptual analysis, and Bernoullian mathematisation. The works of two Jesuit philosophers, Berthold Hauser and Sigismund Storchenau, can be related to this context. The core of their logic of (epistemic) probability is the account of negation (or ‘contradiction’) and implication (or ‘argument’), in particular, the algorithms for computing the reliability of one piece of evidence when compared to the respective counter-evidence and for computing the probability of a conclusion given the probability of its premises. (shrink)

Recent work suggests that people predict how objects interact in a manner consistent with Newtonian physics, but with additional uncertainty. However, the sources of uncertainty have not been examined. In this study, we measure perceptual noise in initial conditions and stochasticity in the physical model used to make predictions. Participants predicted the trajectory of a moving object through occluded motion and bounces, and we compared their behavior to an ideal observer model. We found that human judgments cannot be (...) captured by simple heuristics and must incorporate noisy dynamics. Moreover, these judgments are biased consistently with a prior expectation on object destinations, suggesting that people use simple expectations about outcomes to compensate for uncertainty about their physical models. (shrink)

It is usually believed that a picture of Quantum Mechanics in terms of true probabilities cannot be given due to the uncertainty relations. Here we discuss a tomographic approach to quantum states that leads to a probability representation of quantum states. This can be regarded as a classical-like formulation of quantum mechanics which avoids the counterintuitive concepts of wave function and density operator. The relevant concepts of quantum mechanics are then reconsidered and the epistemological implications of such approach discussed.