We trace the history of the Modern Evolutionary Synthesis, and of genetic Darwinism generally, with a view to showing why, even in its current versions, it can no longer serve as a general framework for evolutionary theory. The main reason is empirical. Genetical Darwinism cannot accommodate the role of development (and of genes in development) in many evolutionary processes. We go on to discuss two conceptual issues: whether natural selection can be the “creative factor” in a new, more general (...) framework for evolutionary theorizing; and whether in such a framework organisms must be conceived as self-organizing systems embedded in self-organizing ecological systems. (shrink)

Perhaps the most readable and accessible of the great works of scientific imagination, The Origin of Species sold out on the day it was published in 1859. Theologians quickly labeled Charles Darwin the most dangerous man in England, and, as the Saturday Review noted, the uproar over the book quickly "passed beyond the bounds of the study and lecture-room into the drawing-room and the public street." Yet, after reading it, Darwin's friend and colleague T. H. Huxley had a different reaction: (...) "How extremely stupid not to have thought of that." Based largely on Darwin's experience as a naturalist while on a five-year voyage aboard H.M.S. Beagle, The Origin of Species set forth a theory of evolution and natural selection that challenged contemporary beliefs about divine providence and the immutability of species. A landmark contribution to philosophical and scientific thought, this edition also includes an introductory historical sketch and a glossary Darwin later added to the original text. Charles Darwin grew up considered, by his own account, "a very ordinary boy, rather below the common standard of intellect." A quirk of fate kept him from the career his father had deemed appropriate--that of a country parson--when a botanist recommended Darwin for an appointment as a naturalist aboard H.M.S. Beagle from 1831 to 1836. Darwin is also the author of the five-volume work Zoology of the Voyage of the Beagle (1839) and The Descent of Man (1871). (shrink)

Mild and massive DNA damage are differentially integrated into the cellular signaling networks and, in consequence, provoke different cell fate decisions. After mild damage, the tumor suppressor p53 directs the cellular response to cell cycle arrest, DNA repair, and cell survival, whereas upon severe damage, p53 drives the cell death response. One posttranslational modification of p53, phosphorylation at Serine 46, selectively occurs after severe DNA damage and is envisioned as a marker of the cell death response. However, the molecular (...) mechanism of action of the p53 Ser46 phospho‐isomer, the molecular timing of this phosphorylation event, and its activating effects on apoptosis and ferroptosis still await exploration. In this essay, the current body of evidence on the molecular function of this deadly p53 mark, its evolutionary conservation, and the regulation of the key players of this response, the p53 Serine 46 kinases, are reviewed and dissected. (shrink)

Fate has always existed in life both as a faith issue appearing in most of the religions and as a vital phenomenon. The unknown sides of fate and the uncertainties related to fate have been a factor that always keeps a human’s sense of curiosity alive. The fate perceptions’ potential of affecting life is high. As an individual’s fate perception is one of the factors determining his attitude to life, and it also affects his behaviours. (...) The fate perceptions’ power of influencing human behaviours was effective in specifying the research topic. The subject of the research was determined as “fate perception”, and university students were selected as the sample group. The research was carried out through metaphor analysis technique based on the phenomenological method. The reason for referring this method rather than directly asking questions related to fate is to reach the real thoughts in the depths of youths’ minds. A total of 211 students participated in the study performed with undergraduate students from different departments of different universities, and the analysis was continued with 163 data sets since the inappropriate data were sorted out. First of all, groups that included the same theme according to the meanings attributed to the fate in the metaphors were formed, and rather than the metaphor, the “because…” part that described it was based on in the grouping. The categories and the metaphors collected in the themes under them were again reviewed relationally, and then the research was analysed by two specialists to ensure the validity and reliability. As a result of the research, it was determined that some of the participants tried to clarify equivalents of the problems related to fate in their minds and to conceptually define the fate while producing metaphors. It was seen that some of the participants associated the fate with religious beliefs in forming metaphors while some of them dealt with it separately from the religion. The most frequently repeated metaphor is the "path" metaphor in the study, in which university students were found to have produced 106 metaphors related to the concept of "fate". This is followed by the metaphors "book" and "wheel". "Scenario, pen, map, crossroads, bunker, line, ship" metaphors are among the top ten most preferred metaphors. After the explanations of the metaphors produced in the scope of the research were examined, they were grouped in terms of their common features, themes were formed, and categories were formed by grouping the themes among themselves. Accordingly, the first category was identified as “fate in the context of characteristic” and its sub-themes were “fate as a(n) unchanging/determined phenomenon, fate as a divertible/preferable phenomenon, fate as an unknown/uncontrollable phenomenon, fate as both determined and divertible phenomenon and fate as a defence mechanism”. The second category was “fate in the context of faith/freedom”. The sub-themes of this category were determined as “the phenomenon of fatalist-inclined fate, the phenomenon of pure faith-based fate, the phenomenon of faith-based voluntaristic fate, the phenomenon of faith-based Cebrî fate, the phenomenon of not faith-based voluntaristic fate, fate contrast”. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Journal of the History of Philosophy 42.2 (2004) 227-229 [Access article in PDF] Philip Pothen. Nietzsche and the Fate of Art. Aldershot, England: Ashgate, 2002. Pp. x + 235. Paper, $29.95. Most scholarship argues that Nietzsche grants art a position of vital importance for culture, history, and philosophy. Philip Pothen seeks to challenge this general view of Nietzsche [End Page 227] while at the same time raising new (...) questions about Nietzsche's thoughts on art and how Nietzsche's views on art relate to his philosophical concerns. He does not locate Nietzsche's "deep suspicion and at times hostility" (1) toward art in a specific period of Nietzsche's thought, but instead traces it from the notebooks of the 1870s through Nietzsche's so-called "positivist period" to the very end of his productive life. The result is an honest attempt to recognize Nietzsche's ambivalent and at times hostile attitude toward that which is often times unquestionably admired.Although the Birth of Tragedy is the central text for most scholarship about Nietzsche's thoughts on art, this scholarship does not generally look to contemporaneous unpublished private writings. By conducting a close reading of Nietzsche's first published work in juxtaposition with selections from the Nachlass, Pothen shows that even as early as the 1870s, Nietzsche was developing some of the major themes of his subsequent writings on art. Nietzsche had begun to make decisive breaks with conceptual presuppositions inherited from Schopenhauer and the Kantian philosophical framework as well as from Wagner.Nietzsche's earlier belief in a rebirth of the Dionysian through works of genius such as Wagner's was severely criticized by Nietzsche himself in his 1886 Preface to the Birth of Tragedy. The second chapter of this book looks at Nietzsche's criticism of the concept of "genius" and the recognition of the "death of art" in modern artists such as Wagner. Pothen shows that Nietzsche gives a highly naturalistic account of genius, criticizing traditional notions that elevate the genius to a higher status than the merely talented artist.According to Pothen, the decadence of modern art, the deception of the artist, and the "end of art" suggests a type of "sickness" for Nietzsche. Art "represents a suppression of the instincts of becoming" (56). Pothen claims the future of art and its possible "death" are much more severe for Nietzsche than, for instance, Hegel. The challenging conclusion is that Nietzsche, not Hegel, properly announces the "death of art" in modernity.What, however, of the "monological work of art" that Nietzsche first formulates in the Gay Science? By considering the fourth part of Thus Spoke Zarathustra as a decisive conclusion and not an inferior appendage, Pothen argues that this work "for All and None" illustrates "a radical and perhaps impossible orientation" (9) that the godless artist must take up according to Nietzsche. It is a creative position "in favor of solitude [Einsamkeit], forgetting [vergessen] and inner strength" (74).Chapter four of Pothen's book addresses the concept of the "will to power." Pothen argues that it is a "metaphysical principle" of explanation that nevertheless undermines certain other metaphysical concepts such as a unified "subject" as well as traditional aesthetic concepts such as artistic autonomy. Pothen challenges Heidegger's claim that art is the "highest expression" of the will to power for Nietzsche while utilizing Heidegger's insights into art to highlight and question previous themes in the book such as the reduction of art to physiology (117-32).Chapter five concentrates on Nietzsche's analysis of the psychology of production and his critique of the Kantian themes of "disinterestedness" and the "judgment of taste." The book ends with a look at Nietzsche's final productive year of 1888. In works such as The Case of Wagner, Nietzsche, Pothen suggests, holds decadent works such as Wagner's as representative of all art produced "in the time of the death of God and the revaluation of all values" (169). For Nietzsche, modernity's inability to understand its own time might "herald the death or the end of this art of works... (shrink)

The decision to undertake this volume was made in 1971 at Lake Como during the Varenna summer school ofthe Italian Physical Society, where Professor Leon Rosenfeld was lecturing on the history of quantum theory. We had long been struck by the unique blend of epistemological, histori cal and social concerns in his work on the foundations and development of physics, and decided to approach him there with the idea of publishing a collection of his papers. He responded enthusiastically, and agreed (...) to help us select the papers; furthermore, he also agreed to write a lengthy introduction and to comment separately on those papers that he felt needed critical re-evaluation in the light of his current views. For he was still vigorously engaged in both theoretical investigations of, and critical not reflections on the foundations of theoretical physics. We certainly did conceive of the volume as a memorial to a 'living saint', but rather more practically, as a useful tool to place in the hands of fellow workers and students engaged in wrestling with these difficult problems. All too sadly, fate has added a memorial aspect to our labors. We agreed that in order to make this book most useful for the con temporary community of physicists and philosophers, we should trans late all non-English items into English. (shrink)

Darwin’s explanation of biological speciation in terms of variation and natural selection has revolutionised biological thought. However, while his principle of natural selection, the fitness principle, has shaped biology until the present, its interpretation changed more than once during the almost 150 years of its history. The most striking change of the status of the principle is that, in the middle of the 20th century, it transmutated from an often disputed, groundbreaking insight into a tautology. Moreover, not only (...) the interpretation of the fitness principle, but the whole body of biological knowledge was subjected to significant modifications. In this paper, I relate modifications of the fitness principle to those of the respective body of biological knowledge. This body of knowledge is conceived as a Quinean web of belief. After an exposition of Darwin’s conception of the principle, which equated fitness with adaptedness to the environment, several of its changes are analysed with respect to different webs of biological knowledge. It is concluded that the different interpretations and the reshaping of the fitness principle are rational responses to the modified systems of background knowledge, which saved the coherence of the web of biological knowledge in each single case. (shrink)

Truth appears to be a predicate of sentence-like structures. This raises the question of what a sentence is (or what it is to be sentence-like) such that it is truth-apt. A natural move is to treat sentences and truth-aptness as somehow conceptually or metaphysical coeval—made for each other. This resolution conflicts, however, with now standard approaches in syntactic theory that treat sentences as mere epiphenomena. Siding with the developments in syntax, the paper argues that truth-aptness properly belongs, not to sentences, (...) but to clauses as structures that can be selected by verbs that specify truth-apt states. It is further argued that this arrangement is perfectly consistent with truth-conditional semantics. (shrink)

The ‘model approach’ facilitates a quantitative-oriented study of conceptual changes in large corpora. This paper implements the ‘model approach’ to investigate the erosion of the traditional art-nature distinction in early modern natural philosophy. I argue that a condition for this transformation has to be located in the late scholastic conception of final causation. I design a conceptual model to capture the art-nature distinction and formulate a working hypothesis about its early modern fate. I test my hypothesis on a selected (...) corpus of 25 works published in the Dutch academic milieu between 1607 and 1748. I analyse the corpus through a procedure based on concordancing of keywords associated with the model. I argue that the results obtained constitute a successful pilot study for the implementation of the model approach on larger scale research. (shrink)

A growing interest in and concern about the adequacy and fairness of modern peer-review practices in publication and funding are apparent across a wide range of scientific disciplines. Although questions about reliability, accountability, reviewer bias, and competence have been raised, there has been very little direct research on these variables.The present investigation was an attempt to study the peer-review process directly, in the natural setting of actual journal referee evaluations of submitted manuscripts. As test materials we selected 12 already published (...) research articles by investigators from prestigious and highly productive American psychology departments, one article from each of 12 highly regarded and widely read American psychology journals with high rejection rates (80%) and nonblind refereeing practices.With fictitious names and institutions substituted for the original ones (e.g., Tri-Valley Center for Human Potential), the altered manuscripts were formally resubmitted to the journals that had originally refereed and published them 18 to 32 months earlier. Of the sample of 38 editors and reviewers, only three (8%) detected the resubmissions. This result allowed nine of the 12 articles to continue through the review process to receive an actual evaluation: eight of the nine were rejected. Sixteen of the 18 referees (89%) recommended against publication and the editors concurred. The grounds for rejection were in many cases described as “serious methodological flaws.” A number of possible interpretations of these data are reviewed and evaluated. (shrink)

It is tempting to invoke organismal selection as perpetually optimizing the function of any given gene. However, natural selection can drive genic functional change without improvement of biochemical activity, even to the extinction of gene activity. Detrimental mutations can creep in owing to linkage with other selectively favored loci. Selection can promote functional degradation, irrespective of genetic drift, when adaptation occurs by loss of gene function. Even stabilizing selection on a trait can lead to divergence of (...) the underlying molecular constituents. Selfish genetic elements can also proliferate independent of any functional benefits to the host genome. Here we review the logic and evidence for these diverse processes acting in genome evolution. This collection of distinct evolutionary phenomena – while operating through easily understandable mechanisms – all contribute to the seemingly counterintuitive notion that maintenance or improvement of a gene's biochemical function sometimes do not determine its evolutionary fate. (shrink)

There is only one physically possible process that builds and operates purposive systems in nature: natural selection. What it does is build and operate systems that look to us purposive, goal directed, teleological. There really are not any purposes in nature and no purposive processes ether. It is just one vast network of linked causal chains. Darwinian natural selection is the only process that could produce the appearance of purpose. That is why natural selection must have built (...) and must continually shape the intentional causes of purposive behavior. Fodor’s argument against Darwinian theory involves a biologist’s modus tollens which is a cognitive scientist’s modus ponens. Assuming his argument is valid, the right conclusion is not that Darwin’s theory is mistaken but that Fodor’s and any other non-Darwinian approaches to the mind are wrong. It shows how getting things wrong in the philosophy of biology leads to mistaken conclusions with the potential to damage the acceptance of a theory with harmful consequences for human well-being. Fodor has shown that the real consequence of rejecting a Darwinian approach to the mind is to reject a Darwinian theory of phylogenetic evolution. This forces us to take seriously a notion that otherwise would not have much of a chance: that when it comes to the nature of mental states, indeterminacy rules. This is an insight that should have the most beneficial impact on freeing cognitive neuroscience from demands on the adequacy of its theories that it could never meet. (shrink)

Kant's writings on history have been enjoying increased recognition by Kant scholars, and Peter Fenves's A Peculiar Fate fits this trend. But here the similarity with mainstream Kant studies abruptly ends. This is no ordinary monograph on Kant's philosophy of history: neither in terms of the selection of Kant's writings discussed by its author, nor in terms of its style, nor in terms of its philosophical approach.

The theory of natural selection is a rich systematization of biological knowledge without a first principle. When formulations of a proposed principle of natural selection are examined carefully, each is seen to be exhaustively analyzable into a proposition about sources of fitness and a proposition about consequences of fitness. But whenever the fitness of an organic variety is well defined in a given biological situation, its sources are local contingencies together with the background of laws from disciplines other (...) than the theory of natural selection; and the consequences of fitness for the long range fate of organic varieties are essentially applications of probability theory. Hence there is no role and no need for a principle of the theory of natural selection, and any generalities that may hold in that theory are derivative rather than fundamental. (shrink)

Lives of the stoics (Zeno, Aristo, Herillus, Cleanthes, Sphaerus, Chrysippus) on philosophy -- Logic and theory of knowledge -- Perception, knowledge, and sceptical attack -- The stoic-academic debate and Cicero's testimony -- Conceptions and rationality -- Physics -- Theology -- Bodily and non-bodily realities -- Structures and powers -- The soul -- Fate -- Ethics -- The general account in Diogenes Lartius -- The account preserved by Stobaeus -- The account in Cicero on goals -- Other evidence for stoic (...) ethics -- Passions and the goal : criticism within the stoic school and the evidence of Galen -- A critique from the academic-peripatetic point of view -- Pyrrhonist critique of basic ethical concepts -- Later stoic ethics : a sampler -- Musonius Rufus -- Seneca -- Epictetus. (shrink)

Why is the human imagination to blame for the worst crimes of the twentieth century? Why is progress a pernicious myth? Why is contemporary atheism just a hangover from Christian faith? John Gray, author of Straw Dogsand Black Mass, is one of the most original and iconoclastic thinkers of our time. In this pugnacious and brilliantly readable collection of essays from across his career, he smashes through humanity's most cherished beliefs to overturn our view of the world, and our place (...) in it. 'If humans are different from other animals it is chiefly in being governed by myths, which are not creations of the will but creatures of the imagination.' 'No traditional myth is as untruthful as the modern myth of progress. All prevailing philosophies embody the fiction that human life can be altered at will. Better aim for the impossible, they say, than submit to fate. Invariably, the result is a cult of human self-assertion that soon ends in farce.'. (shrink)

This paper examines selected writings of the American science writer Waldemar Kaempffert, Science Editor for the New York Times, in public support of Otto Neurath, his Isotype projects, and his Unity of Science Movement. Attention is focused first on Kaempffert’s writings in the 1930s, when some intellectuals, the American public, and their elected leaders were relatively sympathetic with Neurath’s quest to unify the sciences in ways that would advance and direct scientific research toward practical goals. Attention then turns to the (...) 1940s to examine the debate over the nature, scope, and limits of wartime research and Vannevar Bush’s call for a national institution to support research. Against Bush, James Bryant Conant, and others, Kaempffert argued vigorously for a foundation that would adopt values and methods of the Unity of Science Movement, but he lost that argument as the National Science Foundation finally took shape. To suggest that this public debate influenced not only the decline of Neurath’s Unity of Science Movement but the scholarly development of history and philosophy of science after the war, the paper considers early writings and events in the life of Conant’s protégé Thomas Kuhn, whose Structure of Scientific Revolutions helped shape that development. (shrink)

The major moral issues of our time have been made vital and immediate by the convergence of numerous factors. Among these are a technology that has produced the threat of nuclear holocaust, that can maintain life beyond the death of the brain, that can destroy the natural world, and that produces deadly, indestructible waste. There is a new sensitivity to the injustices suffered by minorities. Impoverishment and starvation are now the fate of millions. Political tyranny is a continuing threat. (...) Finally, the rise of a new religiousness has had an impact on morals and public affairs. In these provocative essays chosen from The Tanner Lectures on Human Values and first published in 1987, four internationally distinguished scholars explore the moral implications of these issues in today's world. (shrink)

Alternative non‐B‐DNA conformations formed under physiological conditions by sequences called flipons include left‐handed Z‐DNA, three‐stranded triplexes, and four‐stranded i‐motifs and quadruplexes. These conformations accumulate and release energy to enable the local assembly of cellular machines in a context specific manner. In these transactions, nucleosomes store power, serving like rechargeable batteries, while flipons smooth energy flows from source to sink by acting as capacitors or resistors. Here, I review the known biological roles for flipons. I present recent and unequivocal findings showing (...) how innate immune responses are regulated by Z‐flipons that identify endogenous RNAs as self. Evidence is also presented supporting important roles for other flipon classes. In these examples, the dynamic exchange of energy between flipons and nucleosomes enables rapid switching of genetic programs without altering flipon sequence. The increased phenotypic diversity enabled by flipons drives their natural selection, with adaptations evolving faster than is possible by codon mutation alone. (shrink)

Sociological, economic and evolutionary paradigms of human agency have often seen social agents either as the rational controllers of their fate or as marionettes on the strings of historical, functional or adaptive necessity. They found it therefore difficult to account for the variability, intentionality and creativity of human behaviour and for its frequently redundant or harmful results. This paper argues that human agency is a product of evolution, but that genetic variation and inheritance can only provide a limited explanation (...) of its complex nature. The primary evolutionary problem which human agents face while they are alive is not to adapt to stable environments, but to respond flexibly and creatively to a contingent, uncertain world. Variation and selection therefore take two connected but distinct forms, one external, genetic, and inherited across generations, the other internal and cognitive, and operating during the lifetime of individuals. An examination of this lived part of evolution provides a better understanding of key properties of agency. (shrink)

Cosmology seems extremely remote from everyday human practice and experience. It is usually taken for granted that cosmological data cannot rationally influence our beliefs about the fate of humanity—and possible other intelligent species—except perhaps in the extremely distant future, when the issue of “heat death” (in an ever-expanding universe) becomes actual. Here, an attempt is made to show that it may become a practical question much sooner, if an intelligent community wishes to maximize its creative potential. We estimate, on (...) the basis of a greatly simplified model, the rate of loss of potentially useful information due to the delay in undertaking the colonization of the largest gravitationally bound structures in an accelerating universe. In addition, we argue for a natural cosmological extension of the classical taxonomy of advanced technological communities given by Kardashev. New developments in the fields of anthropic self-selection and physical eschatology give, for the first time, solid foundations to such results. This may open some new (and possibly urgent) issues in the areas of future policy making and transhumanist studies generally. It may also give us a slightly better perspective on the SETI endeavor. (shrink)

Charles Lyell’s Principles of Geology is widely regarded as one of the great works of 19th century science, and one of the most influential works in the entire history of the earth sciences. Yet the standard critical interpretation of the Principles makes such high regard and influence look puzzling at best. We are told, for instance, that Lyell’s argument rests on a contentious a priori methodological distinction between scientific and non-scientific explanations, the former featuring observed causes at their present intensities, (...) the latter featuring anything else. 2 We are also told that Lyell simply assumes a priori that. (shrink)

David and Mary Norton present the definitive scholarly edition of one of the greatest philosophical works ever written. This second volume begins with their 'Historical Account' of the Treatise, an account that runs from the beginnings of the work to the period immediately following Hume's death in 1776, followed by an account of the Nortons' editorial procedures and policies and a record of the differences between the first-edition text of the Treatise and the critical text that follows. The volume continues (...) with an extensive set of 'Editors' Annotations', intended to illuminate Hume's texts; a four-part bibliography of materials cited in both volumes; and a comprehensive index. (shrink)

David and Mary Norton present the definitive scholarly edition of one of the greatest philosophical works ever written. This first volume contains the critical text of David Hume's Treatise of Human Nature, followed by the shortin which Hume set out the key arguments of the larger work; the volume concludes with A Letter from a Gentleman to his Friend in Edinburgh, Hume's defence of the Treatise when it was under attack from ministers seeking to prevent Hume's appointment as Professor of (...) Moral Philosophy at the University of Edinburgh. (shrink)

Dans son dernier article de 1954, Solvable and Unsolvable Problems, Turing répète le résultat fondamental de 1936 dans lequel est formulée l’impossibilité de résoudre tout problème algorithmique à l’aide d’une méthode universelle. Il expose ce résultat en le reliant à une notion qui paraît simple et accessible à tous : le jeu. Mais qu’est-ce qui est au juste entendu par cette notion de jeu ? S’agit-il d’un simple objet mathématique ou n’y a-t-il pas ici une notion qui touche à l’ordre (...) du monde dans son ensemble ? N’y a-t-il pas chez Turing l’intuition que la cybernétique transformera le monde en une chose contrôlable et organisable, à l’image d’un grand Jeu ? Dans la mesure où le développement des machines à calculer dépasse le strict cadre des techno-sciences, peut-on voir là le déploiement d’un Jeu dont, nous dit Héraclite, nous serions nous-mêmes les pions ? (shrink)

Dans son dernier article de 1954, Solvable and Unsolvable Problems, Turing répète le résultat fondamental de 1936 dans lequel est formulée l’impossibilité de résoudre tout problème algorithmique à l’aide d’une méthode universelle. Il expose ce résultat en le reliant à une notion qui paraît simple et accessible à tous : le jeu. Mais qu’est-ce qui est au juste entendu par cette notion de jeu? S’agit-il d’un simple objet mathématique ou n’y a-t-il pas ici une notion qui touche à l’ordre du (...) monde dans son ensemble? N’y a-t-il pas chez Turing l’intuition que la cybernétique transformera le monde en une chose contrôlable et organisable, à l’image d’un grand Jeu? Dans la mesure où le développement des machines à calculer dépasse le strict cadre des techno-sciences, peut-on voir là le déploiement d’un Jeu dont, nous dit Héraclite, nous serions nous-mêmes les pions? (shrink)

Recently, some Newton scholars have argued that Newton is an empiricist about metaphysics—that ideally, he wants to let advances in physical theory resolve either some or all metaphysical issues. But while proponents of this interpretation are using ‘metaphysics’ in a very broad sense, to include the ‘principles that enable our knowledge of natural phenomena’, attention has thus far been focused on Newton’s approach to ontological, not epistemological or methodological, issues. In this essay, I therefore consider whether Newton wants to let (...) physical theory bear on the very ‘principles that enable our knowledge’. By examining two kinds of argument in the Principia, I contend that Newton can be considered a methodological empiricist in a substantial respect. I also argue, however, that he cannot be a ‘radical empiricist’—that he does not and cannot convert all methodological issues into empirical issues.Keywords: Newton; Scientific method; Regulæ Philosophandi; Induction; Empiricism. (shrink)

This review essay brings together five books on various aspects of Nietzsche’s thinking and writing from the last four years, from different cultural and political contexts, but also spanning a wide methodological range. The general question of how to orient ourselves in Nietzsche-scholarship is inspired by the title of Werner Stegmaier’s book which invites the reader to compare Nietzsche and Niklas Luhmann. It also invites us to contemplate the more general question of how to bring Nietzsche’s thinking into a dialogue (...) with the human and social sciences. A central question concerns the temporality of Nietzsche’s thinking: is Nietzsche’s thinking a thing of the past that primarily necessitates a historical interpretation, or can it still open up ways toward the future. As this review highlights, many contemporary readers of Nietzsche continue to see themselves as working to “save” his texts from fateful misinterpretations. The last part of the review focuses on the new textual, or “poesiological” approach and the importance of seeing Nietzsche not primarily as someone professing a doctrine, but as the creator of uniquely multilayered texts. (shrink)

A Treatise of Human Nature, David Hume's comprehensive attempt to base philosophy on a new, observationally grounded study of human nature, is one of the most important texts in Western philosophy. It is also the focal point of current attempts to understand 18th-century western philosophy. The Treatise addresses many of the most fundamental philosophical issues: causation, existence, freedom and necessity, and morality. The volume also includes Humes own abstract of the Treatise, a substantial introduction, extensive annotations, a glossary, a comprehensive (...) index, and suggestions for further reading. (shrink)

The Description for this book, David Hume: Common-Sense Moralist, Sceptical Metaphysician, will be forthcoming.

David Hume is, arguably, the most important philosopher ever to have written in English. Although best known for his contributions to epistemology, metaphysics, and the philosophy of religion, Hume also made substantial and influential contributions to psychology and the philosophy of mind, ethics, the philosophy of science, political and economic theory, political and social history, and, to a lesser extent, aesthetic and literary theory. All facets of Hume's output are discussed in this volume, the first genuinely comprehensive overview of his (...) work. The picture that emerges is of a thinker who, though critical to the point of scepticism, was nonetheless able to build on that scepticism a profoundly important, and still viable, constructive philosophy. (shrink)

David and Mary Norton present the definitive scholarly edition of Hume's Treatise, one of the greatest philosophical works ever written. This set comprises the two volumes of texts and editorial material, which are also available for purchase separately. -/- David Hume (1711 - 1776) is one of the greatest of philosophers. Today he probably ranks highest of all British philosophers in terms of influence and philosophical standing. His philosophical work ranges across morals, the mind, metaphysics, epistemology, religion, and aesthetics; he (...) had broad interests not only in philosophy as it is now conceived but in history, politics, economics, religion, and the arts. He was a master of English prose. -/- The Clarendon Hume Edition will include all of his works except his History of England and minor historical writings. It is the only thorough critical edition, and will provide a far more extensive scholarly treatment than any previous editions. This edition (which has been in preparation since the 1970s) offers authoritative annotation, bibliographical information, and indexes, and draws upon the major advances in textual scholarship that have been made since the publication of earlier editions - advances both in the understanding of editorial principle and practice and in knowledge of the history of Hume's own texts. (shrink)

David Hume is, arguably, the most important philosopher ever to have written in English. Although best known for his contributions to epistemology, metaphysics, and the philosophy of religion, Hume also made substantial and influential contributions to psychology and the philosophy of mind, ethics, the philosophy of science, political and economic theory, political and social history, and, to a lesser extent, aesthetic and literary theory. All facets of Hume's output are discussed in this volume, the first genuinely comprehensive overview of his (...) work. The picture that emerges is of a thinker who, though critical to the point of scepticism, was nonetheless able to build on that scepticism a profoundly important, and still viable, constructive philosophy. (shrink)

In response to kenneth winkler's criticism of my suggestion (found in my "david hume: common sense moralist, sceptical metaphysician") that frances hutcheson embraced an interesting form of moral realism. i show important differences between hutcheson and locke, amplify my previous account of hutcheson's notion of concomitant ideas, and provide evidence that hutcheson's contemporaries, including his student adam smith, believed him to have maintained "that there is a real and essential distinction between vice and virtue". ("theory of moral sentiments").

Volumes 1 and 2 of Hume’s Treatise of Human Nature, first published in January 1739, were soon after publication the subject of five notices and four reviews. Volume 3, published at the end of October 1740, received no notices and was reviewed only in the Bibliothèque raisonnée. This anonymous review of vol. 3 is of interest not only for David Norton is Professor of Philosophy Emeritus, McGill University, and Adjunct Professor of Philosophy, University of Victoria. His address is 8-4305 Maltwood (...) Lane, Victoria, BC, Canada V8X 5G9. what it says about Hume’s views as set out in the third book of the Treatise, but also because of questions that have arisen about the authorship of this and an earlier review of vol. 1 of the Treatise published in the same journal. In Part I of this paper we begin by reviewing the grounds for attributing to Pierre Des Maizeaux the notice of vols. 1 and 2 of the Treatise published by the Bibliothèque raisonnée in its April–June, 1739 issue. We then focus principally on the question of the authorship of the review of vol. 3 of the Treatise published by the Bibliothèque raisonnée in its April–June, 1741 issue, but we also consider in passing the grounds that have been offered for attributing to Francis Hutcheson the critical components of the Bibliothèque raisonnée review of vol. 1 of the Treatise. In Part II of the paper we present a transcription of the French text, never before reprinted, of this review. Part III is a new English translation of this text. In an effort to show the differences between the sense of the Treatise presented by translated quotations of it and Hume’s original texts, Part IV offers some three-column comparisons of three relatively lengthy French “quotations” of Treatise 3 found in the review, our back-translations of these texts, and the versions of these texts found in the Treatise. It then offers in a similar format, comparisons of the present and earlier translations of passages of the review of vol. 3. (shrink)

Demonstrates there are two separate (albeit remarkably similar) versions of the philosopher's engraved bookplate. Presents arguments as to which is the earlier. Speculates that the later version was produced for Hume's favorite nephew and the inheritor of his library, David Hume the Younger.

Although best known for his contributions to the theory of knowledge, metaphysics, and philosophy of religion, Hume also influenced developments in the philosophy of mind, psychology, ethics, political and economic theory, political and social history, and aesthetic theory. The fifteen essays in this volume address all aspects of Hume's thought. The picture of him that emerges is that of a thinker who, though often critical to the point of scepticism, was nonetheless able to build on that scepticism a constructive, viable, (...) and profoundly important view of the world. Also included in this volume are Hume's two brief autobiographies and a bibliography suited to those beginning their study of Hume. This second edition of one our most popular Companions includes six new essays and a new introduction, and the remaining essays have all been updated or revised. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:189 HUME'S MORAL ONTOLOGY* My concern here is the claim, made in my recent book, that Hume is a moral realist. In general terms I would describe this book as one of several that represent a sustained effort to consider Hume within an eighteenth-century context, an effort to see him not as a timeless figure, or to treat him as a brilliantly successful contemporary of ourselves, but as a (...) brilliant eighteenth-century philosopher responding to eighteenth-century issues with, for all his timelessness, eighteenth-century conceptual tools and 2 from an eighteenth-century perspective. It would be hopelessly naive to suppose that any of us can view Hume without any historical distortion, but it is equally naive to read Hume, as he is often read, without historical sensitivity. Furthermore, such insensitivity closes us off from what is uniquely valuable about Hume, for, instead of seeing his writings as the consequence of his unique efforts to confront and answer the philosophical questions posed to him, the historically insensitive read into him their own questions and their own answers. The past studied as an echo of the present is of little interest (and none of that intrinsic), nor can there be much value in the study of those who saw but through a glass, darkly, the truths now so apparent to us. Our intellectual past is important to us because it is different from our intellectual present, and not because it seconds what we presume already to know. I was entirely serious, then, when I said that both the plausibility, and the very meaning of my claim that Hume is a common-sense moralist or a moral realist depends upon considering this claim — and, consequently, Hume — within a particular philosophical context. It will not do to suppose that moral realism 190 is a term with an eternal, unchanging, and Platonic connotation, and then to reject my suggestion outright because Hume was, as I would certainly agree, virtually without sympathy for anything revealing a tincture of Platonism. Philosophical terms as well as philosophical issues are historical, changing entities; it is those who think or act otherwise who smuggle 4 Platonism into the discussion. Doubtless, however, some of the misunderstanding to which I refer is my own responsibility. I can join Hume in saying "I have found by experience, that some of my expressions have not been so well chosen, as to guard against all 5 mistakes in the readers," and so I shall here offer some clarifications of my view. I. To begin, I wish to bring together in one place evidence of the significant qualifications I put on my claim about Hume's moral realism. Taken together, these remarks show that my position is consistent with the widely held (and generally correct, I would say) view that Hume is in one highly important sense a naturalist, and that I ascribe to him a realism that is neither Platonic, Scholastic, Cartesian, nor Hutchesonian: A. If naturalism is thought to be the view "that the whole of the universe or experience may be accounted for by a method like that of the physical sciences," then Hume must certainly be called a naturalist because of his efforts to extend the "experimental Method of Reasoning into moral Subjects".... Hume is a naturalist in that he sought to produce coherent philosophical explanations without the slightest recourse to supernatural entities or transcendental principles... an obvious example of this kind of naturalism... is his attempt to explain moral values as derived from human nature or from, that is, human beings as constituted and active in the world (DH 15-16). 191 B. By no stretch of the imagination can Hume be supposed to have borrowed this providential aspect of Hutcheson's thought, not even in morals (DH 54; also see p. 93). C I submit that /Hume/ holds that vice and disapprobation are not identical and that moral qualities are not merely sentiments but, rather, the objective correlates of sentiments. /Footnote:/ No rash conclusions should be drawn from this claim about objective correlates. I do not suggest that virtue and vice are objects in the ordinary sense (physical objects), or that they are transcendently existing qualities of... (shrink)