Designer babies are often presented in the popular media as a kind of apocalyptical spectre of things to come in a brave new world where reproduction is the province of white coated scientists and potential parents in pursuit of trophy children. In this realm physical, intellectual, and social perfection is sought through the manipulation of genes and selection of favoured traits and attributes to the detriment of individuals who cannot compete and of society more generally through the loss (...) of natural selection. It is therefore a pleasure to discover a short readable book that sets out the discussion and its many nuances in concise and accurate terms that will be accessible to all and should help to dispel some of these science fiction myths through scholarly debate.This volume is part of a collection of books under the title Debating Matters that sprang out of a series of public debates organised by the Institute of Ideas. The conferences were intended to reinvigorate debate and the contestation of ideas and contemporary issues the Institute regards as “too frequently sidelined”. The arguments are presented by an authoritative who’s who of commentators who offer their own insightful readings of various aspects of the debate. Each essayist confirms the fact that the term “ designer babies ” is an inaccurate reflection of the current ability of science to actively fashion children with selected characteristics, and as a result …. (shrink)

My focus in this paper is the question of the moral acceptability of attempts to modify the human genome. Much of the debate in this area has revolved around the distinction between supposedly therapeutic modification on the one hand, and eugenic modification on the other. In the first part of the paper I reject some recent arguments against genetic engineering. In the second part I seek to distinguish between permissible and impermissible forms of intervention in such a way that does (...) not appeal to the therapeutic/eugenic distinction. If I am right much of what we would intuitively call eugenic intervention will be morally acceptable. Central to my argument is an asymmetry in the way genetic engineers can influence a person's capacities on the one hand and life‐goals on the other. Forms of genetic intervention that have a high probability of producing a mismatch of life‐goals and capacities will be ruled out. (shrink)

Among the many ethical problems brought about by the latest developments in medical sciences is the possibility of creating "designer" babies. In this paper I will look at one such a case from the viewpoint of the Kantian "humanity principle". The various aspects of treating people as a means that can be brought up in discussions about "designer" babies are scrutinised. These will obviously include treating the future child as a mere means, but the proper role (...) of the mother and others involved are also looked at. I will conclude by arguing that, contrary to the usual presuppositions, the humanity principle is of very limited use in discussions about designer babies, in this case and in others too. (shrink)

Among the many ethical problems brought about by the latest developments in medical sciences is the possibility of creating "designer" babies. In this paper I will look at one such a case from the viewpoint of the Kantian "humanity principle". The various aspects of treating people as a means that can be brought up in discussions about "designer" babies are scrutinised. These will obviously include treating the future child as a mere means, but the proper role (...) of the mother and others involved are also looked at. I will conclude by arguing that, contrary to the usual presuppositions, the humanity principle is of very limited use in discussions about designer babies, in this case and in others too. (shrink)

Seventy-five years before Niander Wallace brutally kills a newborn replicant in Blade Runner 2049, the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research was formed. Its formation led to the creation of the Belmont Report, which established guidelines for the treatment of human subjects. Wallace uses a scalpel as the instrument of disposal, of the newborn replicant, stabbing her in the womb, thereby ending her life moments after wishing her a happy birthday. The conjunction of (...) 2049 and the Belmont Report leads us to important questions concerning biomedical research, given that replicants are “bioengineered humans.” For example, is the “defective” replicant a human subject, and thus protected by research guidelines, or is she a product or consumer good that did not meet expectations? (shrink)

An introduction to playing god -- The birth and explosive growth of GMOs -- Human cloning -- Messing with mother nature : the first GMO sapiens -- Build-a-baby better via genetics -- DIY guide to creating GMO sapiens -- Eugenics and transhumanism -- Cultural views on human genetic modification -- GMO sapiens today and tomorrow.

Abstract:Research into the development of stem cell-derived (SCD) gametes in humans, otherwise known asin vitrogametogenesis (IVG), is largely motivated by reproductive aims. Especially, the goal of establishing genetic parenthood by means of SCD-gametes is considered an important aim. However, like other applications in the field of assisted reproduction, this technology evokes worries about the possibility of creating so-called ‘designer babies.’ In this paper, we investigate various ways in which SCD-gametes could be used to create such preference-matched offspring, and (...) what this would mean for the acceptability of IVG, if it is premised that it is morally problematic to ‘design’ offspring. We argue that IVG might facilitate the creation of preference-matched offspring, but conclude that this should not undermine the moral acceptability of IVG altogether—even if one concedes the premise that creating ‘designer babies’ is morally problematic. In the light of this, we also point at a possible inconsistency for a position that condemns the creation of ‘designer offspring,’ while accepting the various endeavors to have genetically related offspring. (shrink)

In this chapter, I argue that children who were selected for particular traits or genetically enhanced might feel, for this reason, less securely, spontaneously and fairly loved by their parents, which would constitute significant harm. ‘Parents’ refers, throughout this chapter, to the people who perform the social function of rearing children, rather than to procreators. I rely on an understanding of adequate parental love which includes several characteristics: parents should not make children feel they are loved conditionally, for features such (...) as intelligence, looks or temperament; they should not burden children with parental expectations concerning particular achievements of the child; and parental love is often expressed in spontaneous enjoyment and discovery of children’s features. This understanding of parental love provides a reason to question the legitimacy of parental use of selection and enhancement and to explain why parents should not engage on a quest for the ‘best child’. (shrink)

Back in 1978, Louise Brown made international headlines simply for being born, the first to do so after in vitro fertilization (IVF). One ethicist acknowledged fears that IVF “might move us toward...

The increasing number of newborns has stimulated the infant market. In particular, the baby stroller, serving as an important life partner for both babies and parents, has attracted more attention from society. Stroller design and functionality are of vital importance to babies' physiological and psychological health as well as brain development. Therefore, in this paper, we propose a modularization design method for the novel four-wheeled baby stroller based on the KANO model to ensure the mechanical safety and involve (...) more functionalities. Manual control of the baby stroller requires the rapid response of human motor systems in a completely controlled manner, which could be a potential risk. To enhance the safety and stability of the stroller motion, especially in situations where manual control is hard to achieve (e.g., sharp turns), we propose an autonomous motion control scheme based on model predictive control. Both the modularization design and the motion controller are verified in the MATLAB simulation environment through path tracking tasks. The feasibility is validated by the satisfactory experimental results with lateral position error in a reasonable range and good trajectory smoothness. (shrink)

ABSTRACTAs our technology rapidly advances, designer babies and other bioethical issues are fast becoming possible. Instead of solely being considered in economic terms, or in terms of accuracy and desirability, ethical questions should also be asked such as ‘is this a good thing to do?’. This article considers whether moral people would ‘design’ and genetically engineer their babies and applies the moral theories of virtue ethics, deontology and utilitarianism to help guide our ethical decision-making in relation to (...) this complex issue. Even if we can do something, we should pause and consider whether or not we should. (shrink)

The concept of cuteness, which can evoke positive emotions in people, is an essential aspect to consider in artificial intelligence design. This study aimed to investigate whether the use of baby schema designed avatars in computer-mediated communication elicits higher positive attitudes than neutral avatars and whether the ethnicity of the cute avatars influences individuals' perceived level of cuteness. 485 participants from Israel and Japan viewed six avatar images, including three baby schema avatars of different visual characteristics and ethnicities (Caucasian, Asian, (...) and Black) and three neutral avatars. Participants rated their attitudes on each avatar, and the results revealed that the baby schema designed avatars were rated cuter, more likable, approachable, and pleasant than the neutral mature avatars. Cultural differences were also evident, as the Caucasian baby schema avatar was rated cuter among Japanese participants, while the Asian and Black baby schema avatars were rated cuter among Israeli respondents. The study findings suggest that cute avatar design can serve as a powerful tool for promoting positive interactions in computer-mediated communication, especially in cultures that highly value cuteness, such as Japan. However, the subjective nature of cuteness is evident as attitudes toward cuteness varied significantly across cultures and individuals. This research highlights the significance of cultural diversity and emphasizes the importance of considering cuteness as a crucial aspect of artificial intelligence design, particularly when creating avatars intended to elicit positive emotions from users. Therefore, designers should be mindful of potential cultural and individual differences in the perception of cuteness while developing avatars for various applications. (shrink)

In order to meet the explanatory challenge levelled against non-representationalist views on cognition, radical enactivists claim that cognition about potentially absent targets involves the socioculturally scaffolded capacity to manipulate public symbols. At a developmental scale, this suggests that higher cognition gradually emerges as humans begin to master language use, which takes place around the third year of life. If, however, it is possible to show that pre-linguistic infants represent their surroundings, then the radical enactivists’ explanation for the emergence of higher (...) cognition is defeated. In this paper, I critically assess experiments designed to show that pre-linguistic infants inherit representational abilities. I begin by outlining these experiments in Sect. 2. In Sect. 3, I argue that these experiments only succeed in supporting widespread representationalism by committing a particular kind of circular reasoning, which I call conjunctivist reasoning due to its origins in the debates about the nature of perception. I conclude by developing two independent yet congruent enactivist lines of interpretation for the experiments discussed in 2. I explain the infants’ responses to atypical experimental conditions based on agent-environment codetermination and then I argue that surprise behavior can be explained in terms of embodied habits and unfulfilled anticipation. (shrink)

The Baby Care Scale was designed to assess the involvement of father in infant care during pregnancy and the postpartum period. This study aimed to examine the psychometric characteristics of the BCS – antenatal and BCS – postnatal versions. A sample of 100 primiparous fathers completed the BCS-AN and/or the BCS-PN and self-reported the measures of anxiety and depressive symptoms and of father–infant emotional involvement during pregnancy and the postpartum period, respectively. Good internal consistency was found for both the BCS-AN (...) and the BCS-PN. A two-factor model was found for both versions of the instrument: household tasks and infant care tasks. The BCS-AN and BCS-PN subscales revealed good internal consistency. Higher scores on the BCS-AN predicted higher scores on the BCS-PN. Significant associations were found among the BCS, depressive and anxiety symptoms, and father–infant emotional involvement, revealing good criterion validity. This study suggested that both the BCS-AN and the BCS-PN are reliable multidimensional self-report measures that assess the involvement of father in infant care during pregnancy and the postpartum period. (shrink)

It seems certain that one day we will allow the genetic technology which will enhance our offspring. A highly effective new tool, called CRISPR, which allows for carving out genes, is already being used to edit the genomes of animals. In July 2017, the FDA legalized that germline drugs for therapeutic purposes could be sold in the market. It is a high time, now, that we need engage in discussions about the ethics of germline intervention. To contribute to the discussion (...) by showing our thought and to educate the public, we write this paper. (shrink)

Livengood and Sytsma (2020) challenge the Compositionality Constraint of Actual Causation (CCAC), according to which each intermediary of a causal chain is an effect of its predecessor and a cause of its successor link. In several studies, they find support for their hypothesis that the CCAC is not in accordance with ordinary causal attributions of laypeople. We argue that there are three interrelated problems in their studies’ design that we call the Causality-Responsibility Confusion (CRC), the Intermediary-Ontology Confusion (IOC), and the (...) Cause-End Questioning (CEQ). Avoiding the CRC, the IOC, and the CEQ leads to strong empirical support for the CCAC. (shrink)

Advances in genomic technologies such as CRISPR‐Cas9, mitochondrial replacement techniques, and in vitro gametogenesis may soon give us more precise and efficient tools to have children with certain traits such as beauty, intelligence, and athleticism. In this paper, I propose a new approach to the ethics of reproductive genetic engineering, a human rights approach. This approach relies on two claims that have certain, independent plausibility: (a) human beings have equal moral status, and (b) human beings have human rights to the (...) fundamental conditions for pursuing a good life. I first argue that the human rights approach gives us a lower bound of when reproductive genetic engineering would be permissible. I then compare this approach with other approaches such as the libertarian, perfectionist, and life worth living approaches. Against these approaches, I argue that the human rights approach offers a novel, and more plausible, way of assessing the ethics of reproductive genetic engineering. (shrink)

Alison Gopnik and her collaborators have recently proposed a bold and intriguing hypothesis about the relationship between scientific cognition and cognitive development in childhood. According to this view, the processes underlying cognitive development in infants and children and the processes underlying scientific cognition are _identical_. We argue that Gopnik’s bold hypothesis is untenable because it, along with much of cognitive science, neglects the many important ways in which human minds are designed to operate within a social environment. This leads to (...) a neglect of _norms_ and the processes of _social_ _transmission_ which have an important effect on scientific cognition and cognition more generally. (shrink)

Prometheus has grown four years older since its last and highly controversial special issue, published in 2017 on the Shaken Baby Debate. But, as always, Prometheus is committed to open discussion and dissemination of scientific research, regardless of the potential backlash or controversy that may ensue from such a venture, a venture that is at the core of authentic scholarship. Since the beginning of 2020, the world has changed irrevocably, making once-held norms seem obsolete in favour of new ways of (...) being in the world and new technologies emerging to face these new ways of living. Although it has been a long-held insight in the philosophy of technology that technical systems are carriers of values, the SARS-CoV-2 pandemic has made manifest how these values, and their incarnations in sociotechnical systems, can likewise change. Prometheus has, since its inception, danced in tandem with the critical interpretations, theories, and methods for understanding innovation, and how innovations fundamentally impact and are impacted by the world in which they emerge and are situated. For this reason, Steffen Steinert, Tristan de Wildt, and I chose to guest edit this special issue on designing for value change and chose Prometheus as its home. (shrink)

Despite major advances in research on musical ability in infants, relatively little attention has been paid to individual differences in general musicality in infants. A fundamental problem has been the lack of a clear definition of what constitutes “general musicality” or “musical ability” in infants and toddlers, resulting in a wide range of test procedures that rely on different models of musicality. However, musicality can be seen as a social construct that can take on different meanings across cultures, sub-groups, and (...) individuals, and may be subject to change over time. Therefore, one way to get a clearer picture of infant musicality is to assess conceptions of musicality in the general population. Using this approach, we surveyed 174 German adults, asking about their view and conceptions regarding behaviors that characterize a musical child under 3 years. Based on previous studies on adult and child musicality, we designed a survey containing 41 statements describing musical behaviors in children. Participants were asked to rate how indicative these behaviors were of musicality in infants and toddlers. PCA analysis revealed 4 components of musical abilities and behaviors in under-3-year-olds: Musical Communication, Enthusiasm and Motivation, Adaptive Expressiveness, and Musical Abilities as traditionally defined. Professional background and musical expertise of the respondents did not significantly influence participants’ conceptions. Our results suggest that, in order to capture musicality in young children, a wider range of skills and observable behaviors should be taken into account than those assessed by traditional musical ability tests for young children. (shrink)

Recognizing that GLBTI individuals are often barred from visiting their partners in hospitals or from acting as health care surrogates for incapacitated partners, President Obama directed the Department of Health and Human Services to address these issues. In response, the department amended its rules to prohibit hospitals from restricting, limiting, or denying visitation privileges on the basis of gender identity or sexual orientation. But the changes do not affect the designation of a health care surrogate, a matter largely governed by (...) state law. Therefore, subject to state law, same-sex partners can still be legally barred from making health care decisions for their incapacitated partners, and it remains essential that they execute advance directives and appoint one another as their health care proxies. (shrink)

With the emergence of clustered, regularly interspaced, short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) as one of the most promising new gene-editing techniques, scientists are now endeavoring to apply it to various domains. Among all the possible applications, gene editing in human embryos has received the most attention. Against this background, this article carries out a philosophical study on the ethical problems of human embryo gene editing or designing. Arguments against human embryo gene designing include that parents should be prohibited (...) from deciding their children’s future; commodifying children should be prohibited; the natural reproductive process should not be disturbed; and human embryo gene designing might foster discrimination. Arguments for human embryo gene designing include that parents should have the freedom to design their own babies and this freedom should not be limited; designing babies can promote the happy life of the baby; and totally forbidding embryo gene editing would drive the practice underground, where it would be performed illegally. This article analyzes all of these arguments and points out that all of them have some flaws. In order to draw a thoughtful conclusion, we turn to Confucianism and find a new perspective to determine whether designing babies with CRISPR technology is ethically permissible. (shrink)

The Surfactant, Positive Pressure, and Oxygenation Randomized Trial (SUPPORT) has been the focal point of many different criticisms regarding the ethics of the study ever since publication of the trial's findings in 2010 and 2012. In this article, we focus on a concern that the technical design and implementation details of the study were ethically flawed. While the federal Office Human Research Protections focused on the consent form, rather than on the study design and implementation, OHRP's critiques of the consent (...) form reveal views about the study design and implementation that we believe are fundamentally flawed. These criticisms about the design and implementation of SUPPORT, if generalized, become relevant concerns about these aspects of many comparative effectiveness research studies.Our analytical approach will be to use SUPPORT as a prime example of comparative effectiveness research and show why it challenges some prevailing assumptions about the riskiness of research. We will address five aspects of the study design and implementation: 1) randomization, 2) treatment by protocol, 3) choice of endpoints, 4) lack of a “standard care” control group, and 5) the use of altered oximeters. Examining these aspects will allow us to answer two specific central questions. The first is a methodological question with ethical implications: was the study designed in such a way as to answer the primary study question? The second question is whether the study design added or decreased risk to the babies enrolled in the study compared to babies who were not in the study. (shrink)

In 'Benefit, Disability and the Non-Identity Problem', Hallvard Lillehammer uses the case of a couple who chose to have deaf children to argue against the view that impartial perspectives can provide an exhaustive account of the rightness and wrongness of particular reproductive choices. His conclusion is that the traditional approach to the non-identity problem leads to erroneous conclusions about the morality of creating disabled children. This paper will show that Lillehammer underestimates the power of impartial perspectives and exaggerates the ethical (...) force of partial perspectives, which in turn commits him to providing weak justifications for the choice made by the couple in his example case. (shrink)

IntroductionThe National Institute for Health and Care Excellence guidelines acknowledge the importance of the parent–infant relationship for child development but highlight the need for further research to establish reliable tools for assessment, particularly for parents of children under 1 year. This study explores the acceptability and psychometric properties of a co-developed tool, ‘Me and My Baby’.Study designA cross-sectional design was applied. The MaMB was administered universally with mothers during routine 6–8-week Health Visitor contacts. The sample comprised 467 mothers. Dimensionality of (...) instrument responses were evaluated via exploratory and confirmatory ordinal factor analyses. Item response modeling was conducted via a Rasch calibration to evaluate how the tool conformed to principles of ‘fundamental measurement’. Tool acceptability was evaluated via completion rates and comparing ‘completers’ and ‘non-completers’ demographic differences on age, parity, ethnicity, and English as an additional language. Free-text comments were summarized. Data sharing agreements and data management were compliant with the General Data Protection Regulation, and University of York data management policies.ResultsHigh completion rates suggested the MaMB was acceptable. Psychometric analyses showed the response data to be an excellent fit to a unidimensional confirmatory factor analytic model. All items loaded statistically significantly and substantially on a single underlying factor. The item response modeling showed that most MaMB items fitted the Rasch model. item reliability was high yet the test yielded little information on each respondent, as highlighted by the relatively low ‘person separation index’ of 0.1.Conclusion and next stepsMaMB reliably measures a single construct, likely to be infant bonding. However, further validation work is needed, preferably with ‘enriched population samples’ to include higher-need/risk families. The MaMB tool may benefit from reduced response categories and some modest item wording amendments. Following further validation and reliability appraisal the MaMB may ultimately be used with fathers/other primary caregivers and be potentially useful in research, universal health settings as part of a referral pathway, and clinical practice, to identify dyads in need of additional support/interventions. (shrink)

The ‘What Being the Parent of a New Baby is Like-Revised’ is an instrument designed to measure adaptation to parenthood. In the process of pilot testing and validating the WPL-R in a postpartum Dutch population, we became aware of the potentially sensitive nature of the measure. Despite the ethics committee waiving the invasive nature of the measure, we conducted a survey to explore its possible effect on women’s thoughts and emotions by using the Positive And Negative Affect Schedule to measure (...) changes associated with completion of the WPL-R. Two hundred and fifteen questionnaires were returned. Our findings indicated a change in PANAS scores, implying an intervening effect when using the WPL-R, in research. This raises the question of whether it is acceptable to use a questionnaire with postpartum women without any knowledge of the possible effect it may have, even though the ethics committee has approved the study and considers the measure to be non-invasive. (shrink)

Progress in genetic and reproductive technology now offers us the possibility of choosing what kinds of children we do and don't have. Should we welcome this power, or should we fear its implications? There is no ethical question more urgent than this: we may be at a turning-point in the history of humanity. The renowned moral philosopher and best-selling author Jonathan Glover shows us how we might try to answer this question, and other provoking and disturbing questions to which it (...) leads. Surely parents owe it to their children to give them the best life they can? Increasingly we are able to reduce the number of babies born with disabilities and disorders. But there is a powerful new challenge to conventional thinking about the desirability of doing so: this comes from the voices of those who have these conditions. They call into question the very definition of disability. How do we justify trying to avoid bringing people like them into being? In 2002 a deaf couple used sperm donated by a friend with hereditary deafness to have a deaf baby: they took the view that deafness is not a disability, but a difference. Starting with the issues raised by this case, Jonathan Glover examines the emotive idea of 'eugenics', and the ethics of attempting to enhance people, for non-medical reasons, by means of genetic choices. Should parents be free, not only to have children free from disabilities, but to choose, for instance, the colour of their eyes or hair? This is no longer a distant prospect, but an existing power which we cannot wish away. What impact will such interventions have, both on the individuals concerned and on society as a whole? Should we try to make general improvements to the genetic make-up of human beings? Is there a central core of human nature with which we must not interfere? This beautifully clear book is written for anyone who cares about the rights and wrongs of parents' choices for their children, anyone who is concerned about our human future. Glover handles these uncomfortable questions in a controversial but always humane and sympathetic manner. (shrink)