The discourse on nihilism in the German-speaking world continues to take its orientation primarily from Friedrich Nietzsche’s understanding of nihilism as a historical movement of the decline of values. This means that the aspects of nihilism that are not tied to specific epochs and cultures are not accorded due importance (I). In order to make a reappraisal of nihilism that does justice to these objective contents, I will present a classification of types of nihilism and of arguments that (...) support it. The discussion of the typology of the principal meanings of nihilism points to a loss in relevance of conceptions that take their orientation from Nietzsche (II). The discussion of the arguments testifies to the importance of objective knowledge in the justification of nihilism (III). (shrink)

For several decades, Monographien und Texte zur Nietzsche-Forschung (MTNF) has set the agenda in a rapidly growing and changing field of Nietzsche scholarship. The book series is international in orientation and reflects the entire spectrum of research on Nietzsche. The series publishes monographs and edited volumes that undergo a strict peer-review process. The series is led by an international team of editors.

In contemporary philosophy, there is a widespread distinction between authenticity as self-discovery (which is an essentialist model, inspired by Rousseau, Herder and the Romantic tradition) and authenticity as self-creation (an existentialist model, inspired mainly by Kierkegaard and Sartre). In this paper, I would like to propose a threefold classification, which ads another model of authenticity, irreducible to any of the previous two. This third model is authenticity as self-reinvention, that could be reconstructed from Nietzsche’s philosophy. The self-reinvention model rests on (...) three different, yet interrelated, ideas: 1) Vitalism: The authentic individual wholeheartedly embraces every aspect of his existence, even pain and sufferings, thus proving he truly owns himself. 2) Perspectivism: The authentic individual is able to reinterpret his mental states in the utmost personal manner, through the transvaluation of values (Umwertung aller Werte) and the spiritualization (Vergeistingung) of his drives. 3) Experimentalism: Authenticity is an incessant play, a constant process of identity formation, which corresponds to Nietzsche’s hypothesis of “the subject as multiplicity” and to his ideal of existence as a work of art or of becoming the poet of your life. (shrink)

Experimental vaccines are being developed for the treatment of ‘unhealthy lifestyles’ and associated chronic illnesses. Policymakers and other stakeholders will have to deal with the ethical issues that this innovation path raises: are there morally justified reasons to integrate these innovative biotechnologies in future health policies? Should public money be invested in further research? Focusing on the case of an experimental nicotine vaccine, this article explores the ethical aspects of ‘lifestyle vaccines’ for public health. Based on findings from a qualitative (...) study into a vaccine for smoking cessation, the article articulates possible value conflicts related to nicotine vaccination as an intervention in tobacco control. The ‘vaccinization’ of lifestyle disease piggybacks on the achievements of classic vaccines. Contrary to expectations of simplicity and success, quitting smoking with a vaccine requires a complex supportive network. Social justice and public trust may become important ethical challenges when deciding whether to use further public funds for research or whether to implement these innovative vaccines in the future. (shrink)

Background Massively parallel sequencing techniques, such as whole exome sequencing (WES) and whole genome sequencing (WGS), may reveal unsolicited findings (UFs) unrelated to the diagnostic aim. Such techniques are frequently used for diagnostic purposes in pediatric cases of developmental delay (DD). Yet policy guidelines for informed consent and return of UFs are not well equipped to address specific moral challenges that may arise in these children’s situations. Discussion In previous empirical studies conducted by our research group, we found that it (...) is sometimes uncertain how children with a DD will develop and whether they could come to possess capacities for autonomous decision-making in the future. Parents sometimes felt this brought them into a Catch-22 like situation when confronted with choices about UFs before undergoing WES in trio-analysis (both the parents’ and child’s DNA are sequenced). An important reason for choosing to consent to WES was to gain more insight into how their child might develop. However, to make responsible choices about receiving or declining knowledge of UFs, some idea of their child’s future development of autonomous capacities is needed. This undesirable Catch-22 situation was created by the specific policy configuration in which parents were required to make choices about UFs before being sequencing (trio-analysis). We argue that this finding is relevant for reconfiguring current policies for return of UFs for WES/WGS and propose guidelines that encompass two features. First, the informed consent process ought to be staged. Second, differing guidelines are required for withholding/disclosing a UF in cases of DD appropriate to the level of confidence there is about the child’s future developmental of autonomous capacities. Conclusion When combined with a dynamic consent procedure, these two features of our guidelines could help overcome significant moral challenges that present themselves in the situations of children undergoing genomic sequencing for clarifying a DD. (shrink)

erkennung der Postmodernität: Hilfen für Historiker – und Historiker der Wissenschaften im Besonderen. Ausgehend von einer Unterscheidung zwischen der Postmodernit?t als einer von der Modernit?t durch eine breite Umkehr ihrer kulturellen Grundannahmen abgegrenzten historischen Ära und dem Postmodernismus – einer von den selbsternannten Postmodernisten in der frühen Postmodernität angenommenen intellektuellen Attitüde – thematisiert der Aufsatz zwei grundsätzliche Charakteristika der Postmodernität: Erstens die Umkehrung der kulturellen Rangfolge von Wissenschaft und Technik, worin Postmodernität und Postmodernismus übereinstimmen. Zweitens die Ablösung des Ideals eines (...) methodisch vorgehenden, uneigennützigen Wissenschaftlers, nicht durch ein fragmentiertes Subjekt, wie der Postmodernismus behauptet, sondern durch den einseitig interessierten Unternehmer, welcher unter Missachtung aller Regeln hartnäckig seine Eigeninteressen verfolgt. Diese Umkehr in Bedeutung und Rolle von Wissenschaft und Technologie, die um 1980 begann, ist ein Kennzeichen des Übergangs von der Modernit?t zur Postmodernität. Diese Umkehr ist primär zu erkennen als eine Ablehnung des Regelhaften, des methodischen Vorgehens – mit dem “Methodismus” als einer die Modernität auszeichnenden kulturellen Perspektive – aber auch als eine Ablehnung der Uneigennützigkeit, einer in der Modernität besonders wert geschätzten Geisteshaltung. Postmodernität konstituiert sich somit als diese Umwertung der Werte, die ihre Quelle im ich-fixierten, transgressiven und “risiko”-freudigen postmodernen Individuum und seinen anti-sozialen Annahmen in Bezug auf Persönlichkeit hat. In der Wissenschaftsgeschichte selbst findet sich daher seit circa 1980 ein entsprechender Wandel der wissenschaftlichen Aufmerksamkeit weg von der Wissenschaft und hin zur Technologie. Damit einhergeht eine erstaunliche Vermeidung sozialhistorischer Perspektivierung, wie sie sich nicht zuletzt in der Abkehr von kausalistischen “Einfluss”-Erklärungen zugunsten voluntaristischer “Ressourcen”-Erklärungen spiegelt.cognizing Postmodernity: Helps for Historians – of Science Especially. stmodernity, a historical era demarcated from modernity by a broad reversal in cultural presuppositions, is distinguished from postmodernism, an intellectual posture adopted by self-identified postmodernists early in postmodernity. Two principal features of postmodernity are addressed: first, the downgrading of science and the upgrading of technology in cultural rank – on which postmodernity and postmodernism are in accord; second, the displacement of the methodical, disinterested scientist, modernity's beau ideal, not by a fragmented subject as postmodernism claims, but by the single-minded entrepreneur, resourcefully pursuing his self-interest in disregard of all rules. The reversal in rank and role as between science and technology, setting in circa 1980, is a marker of the transition from modernity to postmodernity. That reversal is to be cognized primarily as rejection of rule-following, of proceeding methodically – ‘methodism’ being the cultural perspective that uniquely distinguished modernity – but also as rejection of disinterestedness, the quality of mind especially highly esteemed in modernity. Postmodernity is constituted by this transvaluation of values, whose well-spring is the egocentric, transgressive , postmodern personality and its anti-social presumptions regarding personhood. Within the history of science itself there has been since circa 1980 a corresponding turn of scholarly attention away from science to technology, and a growing distaste for social perspectives, reflected, i. a., in the rejection of causalist ‘influence’ explanations in favor of voluntarist ‘resource’ explanations. (shrink)

Kynismus und Zynismus waren schon zu Nietzsches Zeit zwei unterschiedliche Begriffe. Kynismus bezeichnet die antike Schule der Kyniker und Zynismus eine moderne Verfallsform der politischen Indifferenz. Aber bei Nietzsche kommt allein das Wort Cynismus vor. Außerdem bezeichnet er sich selbst als einen Cyniker. Was ist damit gemeint? Ist er ein Kyniker oder ein Zyniker? Oder kommt er über beide hinaus? Der Autor führt eine philologische und eine philosophische Untersuchung durch. Die philologische widmet sich Nietzsches Rezeption des Kynismus und Zynismus während (...) seiner Basler Professur. Die philosophische arbeitet zuerst heraus, dass Nietzsche mit seiner Umwertung der Werte in der Nähe des Protokynikers Diogenes von Sinope steht. Dann stellt sie dar, dass die Umwertung der Werte von dem Kynismus ausgeht, mit der Radikalisierung in den Zynismus und Nihilismus verfällt und endlich durch die Überwindung der décadence zum Cynismus avanciert ist. (shrink)

It has been suggested that future application of stem-cell derived gametes might lead to the possibility for same-sex couples to have genetically related children. Still, for this to become possible, the technique of gamete derivation and techniques of reprogramming somatic cells to a pluripotent state would have to be perfected. Moreover, egg cells would have to be derived from male cells and sperm cells from female cells, which is believed to be particularly difficult, if not impossible. We suggest a more (...) plausible scenario to provide same-sex couples with the possibility to parent a child who is genetically related to both parents. Although technical feasibility is an advantage, disadvantages are that cooperation of a donor of the opposite sex is still required and that the partners are genetically linked to the resulting child in a different degree. However, since in our scenario the donor's genetic contribution would not outweigh any of the parents' genetic contribution, this alternative route may ease the fear for a possible parental claim by the donor. Like many other applications in the field of infertility treatment, the goal to create SCD-gametes for reproductive purposes is largely based on the high value attributed to genetic parenthood. Although we believe that genetic relatedness is neither a necessary nor a sufficient condition for ‘good’ parenthood, we do believe that many people may consider our scenario a welcome alternative. (shrink)

Die Frage, ob ein Grundeinkommen für jede Bürgerin und jeden Bürger eine gerechte Institution ist, wird unter Philosophen seit gut 20 Jahren verstärkt diskutiert. Zur Begründung der Institution des Grundeinkommens wird von vielen Denkern eine Überlegung geltend gemacht, die von links-libertären Philosophen entwickelt wurde. Sie beruht auf der Annahme, dass von Natur aus gegebene Dinge und Ressourcen ursprünglich das gemeinsame Eigentum aller Menschen sind und dass private Aneigner derartiger Dinge und Ressourcen deshalb aus Gerechtigkeitsgründen gegenüber den anderen Menschen zur (...) Zahlung einer Entschädigung verpflichtet sind, deren Höhe dem ökonomischen Wert der von ihnen angeeigneten Güter entspricht. In der vorliegenden Untersuchung wird gezeigt, dass diese Begründung des Grundeinkommens auch dann nicht überzeugen kann, wenn man die eigentumstheoretischen Grundannahmen des Links-Libertarismus akzeptiert. Hierfür sind werttheoretische Defizite verantwortlich, die es fraglich erscheinen lassen, ob sich die Größe des ökonomischen Werts der von Natur aus gegebenen Dinge und Ressourcen im Rahmen der links-libertären Philosophie überhaupt überzeugend bestimmen lässt. For a good twenty years now, philosophers have been increasingly discussing whether or not a basic income for every citizen is a just institution. Some of these thinkers ground the institution of basic income on a notion that was developed by left-libertarian philosophers. This notion is based on the claims that things and resources that are naturally given are originally the common possession of all of mankind and that, out of reasons of justice, whoever privately appropriates such things or resources is therefore liable to paying compensation of an amount corresponding to the economic value of the appropriated items. The aim of the present study is to show that even if one accepts the basic assumptions made by left-libertarians about property rights, the above justification of basic income does not hold. This is due to deficits in the theory of value, which render it questionable whether the magnitude of the economic worth of things and resources given in nature can ever be convincingly determined within the framework of left-libertarianism. (shrink)

This book is a large-scale historical reconstruction of liberal legalism, from its inception in the mid-nineteenth century, the moment in which the jurists forged the alliance between political liberalism and legal expertise embodied in classical private law doctrine, to the contemporary anxiety about the possibility of both a liberal solution to the problem of political justification and of law as a respectable form of expert knowledge. Each stage in the history is a moment of synthesis between a substantive and a (...) methodological idea. The former is the liberal political theory of the period, purporting to provide a solution to the problem of political justification. The latter is a conception of legal method or science, supposedly vindicating the access of the expert to the political choices embodied in the law. Thus, each moment in the history of liberal legalism integrates a political theory with a jurisprudential conception. Although it reaches the unsettling conclusion that liberal legalism has largely failed by its own standards, the book urges us to avoid quietism, skepticism or cynicism, in the hope that a deeper understanding of the fragility of our values and institutions inspires a more thoughtful, broadminded and nurtured citizenship. (shrink)

Drawing from a four-year study of US science institutions that support biological control of arthropods, this article examines the decline in biological control institutional capacity in California within the context of both declining public interest science and declining agricultural research activism. After explaining how debates over the public interest character of biological control science have shaped institutions in California, we use scientometric methods to assess the present status and trends in biological control programs within both the University of California (...) Land Grant System and the California Department of Food and Agriculture. We present available data on the number of scientific positions and the types of positions to discuss the impact on the amount of public interest research on biological control in California. We use sociograms to depict how biological control science networks have been reconfigured over time. Our quantitative and qualitative analyses indicate that the following factors contributed to the decline of biological control science in California over the 45-year period analyzed: (1) the institutional reconfiguration of university research priorities; (2) the fraying networks within and increasing specialization of biological control science; (3) the transformation of the social organization of the life science work, including privatization; and (4) the abandonment of this thematic area by civil society activist groups. This broad array of forces suggests that biological control, as a public interest science, will require a deliberate intervention, based on advocacy of clear public interest criteria. (shrink)

Modern consumer society leads a superficial and individualized life characterized by trivial values and ultimately the loss of all purpose. The problem is cultural distortion and the resulting diversification of values, ethics, and meaning. In this regard, consumer culture is a threat to well-being through the environment, health and social structure. The importance of critical discourse on this issue is that it highlights the tension between individual freedom and social justice, feelings of happiness, and levels of consumption.

The article analyzes the values and ideals of modern global society in the realities of the economic crisis, makes a forecast regarding the popularization of new values such as solidarity, brotherhood, equality against the background of discrediting the values of freedom and democracy. In the first part of the work, the author identifies trends and phenomena in modern society that are similar to the position of the society depicted by A.A. Zinoviev in the novel "The Global Humant (...) Hill". First of all, it is the priority of the benefits, efficiency and interests of capital over values, covered with ranting about freedom and democracy, as well as the denigration of communist ideas and their defenders, the use of information technology and technological progress as a surrogate for communication. The author comes to the conclusion that social problems and the spiritual life of the «humant hill», ideological and political discourse have a number of common features with reality. The second part of the article examines the crisis of the values of freedom and democracy, which are widely used in political and humanitarian discourse. Relying on the research of K. Marx, F. Engels, R. Luxemburg, O. Spengler and other philosophers, the author concludes that the interests of capital are hidden behind the declared values, and the modern economic crisis will strengthen social contradictions in society and the exploitation of the lower and middle strata of the population. The need to survive in more difficult economic conditions will lead to the popularization of the values of solidarity, brotherhood, the oblivion of freedom as a value guideline, the concept of freedom in political and ideological discourse will be used much less often. (shrink)

For some time sociologists and philosophers have tended to label present day society “post-industrial” or “post-modern.” Understandable as the wish is to set off the present from the age of advanced capitalism, the terms selected are no less problematic. A new epoch is introduced before the question is even asked, let alone answered, as to how decisive current social changes are, and whether they require that a new epochal boundary be set. The term “post-modern,” moreover, has the additional disadvantage of (...) only naming the new period abstractly. There is an even more drastic disadvantage. Of course, deep economic, technical and social changes can be observed when compared with the second half of the nineteenth century, but the dominant mode of production has remained the same: private appropriation of collectively produced surplus value. (shrink)

Since Ranke, German historiography has been dominated by historicism. History defies conceptualism and systematic analysis; it requires empathetic understanding of the individualities which compose history, a narrative account of the intentions and actions of great individuals and states. Value judgments are to be suspended; military power and foreign policy are stressed. Defeat in World War I had little impact on German historical scholarship. Hintze's attempts at structural analysis and Kehr's efforts to study foreign policy within the framework of domestic history (...) met opposition. Traditional methodological and political assumptions remained important after 1945 in the work of G. Ritter, H. Rothfels, and others; at the same time these assumptions were increasingly questioned by a new generation of historians committed to democratic values who sought to integrate the methods of political science, sociology, and economics with those of history. (shrink)

Der Beitrag untersucht Wittensteins Stellungnahmen zu Nietzshe, die Thesen und Positionen, die er zu Recht oder zu Untrecht ihm zuschreibt, seine Auseinandersetzung mit ihnen und seine Einschätzung von Nietzsche historischer Bedeutung. An Zeugnissen einer direkten Lektüre fehlt es nicht, aber Wittgensteins Bild des Philosophen ist mindestens ebenso stark durch Autoren wie Spengler geprägt. Man hat "a troubling lack of reference to Nietzsche in Wittgenstein's texts and lectures" festellen wollen. Die eingehendere Prüfung des Materials führt zu einem ganz anderen Ergebris. Es (...) werden eine Reihe von Szenarien skizziert, deren Synopse über Nietzsches Bedeutung für Wittgenstein Aufschluss gibt. Die erste belegt Begegnung datiert von 1914: And der Front denkt er über Nietzsches "Feindschaft gegen das Christentum" nach: Dass er sich dabei auf den Antichrist bezieht, wie in der Wittgenstein-Forschung gegnerell angenommen, erweist sich als keineswegs sicher. In den dreißsiger Jahren wird ihm die 'Umwertung aller Werte" zu einer Formel zuerst für die geschichtlich Epoch und dann für seine eigene neue 'Gedankenbewegung'. Nietzsches Präsenz im Wiener Kreis, Wittgensteins zwiespältige Beziehung zu diesem und eine damalige Sicht auf den Zusammenhang zwischen den zwei Philosophien werden ausgehend von Waismanns Buch Logik, Sprach und Philosophie dargestellt. Zu Zarathustras Diktum "Seele ist nur ein Wort für ein Etwas am Leibe" hat Wittgenstein seit Eine philosophische Betrachtung wiederholt Stellung genommen. Der Begriff der Familienähnlichkeit und die Auseinandesetzung mit dem Wiederkunftsgedanken sind Gegenstand der letzen Abschnitte. (shrink)

Farmers markets can offer solutions to several of the biggest problems besetting the US food system: fair prices to farmers; healthy, fresh food for consumers; direct contacts between consumers and farmers; food for food deserts; support for local economies. Awareness of these benefits led us to study the farmers markets of Greater Cincinnati. Markets grew rapidly in the early 1980s, peaked in 2012, and declined 17% by 2018. Sixty-one percent of the markets that started since 1970 have closed. Two types (...) of markets exist: farmer-focused markets, with farmer vendors, and consumer-focused markets, with farmers and specialist vendors. Detailed information about market management shows that managers, the majority of whom are volunteers or underpaid, have insufficient resources to be sustainable. Market decline is often blamed on an oversupply of markets, but other factors are involved: the inability of market personnel and customers to cross class and racial boundaries; the encroachment of online retailers; a scarcity of farmers; market manager failures. Individual markets need to form coalitions and gain sufficient resources from governments or private funders to employ specialists who can assist managers, expand the consumer base, and design promotion campaigns that effectively promote farmers markets in the changing retail food landscape. (shrink)

The book examines the ethical aspect of journalistic activity in an attempt to understand and render explicit the values which guide journalists in their work, but it emphasizes the point that while such values reflect society's existing professional mores, this particular profession is also placed in such a way as to shape the consciousness and values of those who consume its working product. The central question of this work has to do with the ethical implications of journalistic (...) activity, and more exactly, the ethical responsibility of the media in framing public discourse. This question touches on how the journalistic profession conceives its own responsibilities, as reflected in its various professional codes, but it also relates to an account of its formative influence on human sensibilities in a culture in which journalism plays a major role in the interpretation and dissemination of knowledge. (shrink)

Several threads of research towards developing artificial gametes are ongoing in a number of research labs worldwide. The development of a technology that could generate gametes in vitro has significant potential for human reproduction, and raises a lot of interest, as evidenced by the frequent and extensive media coverage of research in this area. We have asked researchers involved in work with artificial gametes, ethicists, and representatives of potential user groups, how they envisioned the use of artificial gametes in human (...) reproduction. In the course of three focus groups, the participants commented on the various aspects involved. The two recurring themes were the strength of the claim of becoming a parent genetically, and the importance of responsible communication of science. The participants concurred that (a) the desire or need to have genetic offspring of one’s own does not warrant the investment of research resources into these technologies, and that (b) given the minefield in terms of moral controversy and sensitivity that characterises the issues involved, how information is communicated and handled is of great importance. (shrink)

In my thesis A Dialogue between Nin and de Beauvoir I use two different hterary forms; the interview and the dispute. In this paper I want to give an impression of how I use one of these literary forms - the interview - and discuss why I have chosen for a combination of different literary forms in my thesis.

Prenatal screening for foetal abnormalities such as Down's syndrome differs from other forms of population screening in that the usual aim of achieving health gains through treatment or prevention does not seem to apply. This type of screening leads to no other options but the choice between continuing or terminating the pregnancy and can only be morally justified if its aim is to provide meaningful options for reproductive choice to pregnant women and their partners. However, this aim should not be (...) understood as maximizing reproductive choice per se. Only if understood as allowing prospective parents to avoid suffering related to living with (a child with) serious disorders and handicaps can prenatal screening be a publicly or collectively funded programme. The alternative of moving prenatal testing outside the healthcare system into the private sector is problematic, as it makes these tests accessible only to those who can afford to pay for it. New developments in prenatal screening will have to be assessed in terms of whether and to what extent they either contribute to or undermine the stated aim of providing meaningful options for reproductive choice. In the light of this criterion, this article discusses the introduction of the new non‐invasive prenatal test (NIPT), the tendency to widen the scope of follow‐up testing, as well as the possible future scenarios of genome‐wide screening and ‘prenatal personalised medicine’. The article ends with recommendations for further debate, research and analysis. (shrink)

The genesis of values occurred in the Garden of Eden when God created man. He instilled in man the value of knowledge, which Satan used as part of his deception. God created man with a core intellect capable of external influence. Our modern culture interprets the world through its values and beliefs, both of which are codified and forged into a worldview. The Christian worldview is predicated upon biblical teaching and interpretation. It is the foundation for family (...) class='Hi'>values. These values are prevalent in the Book of Genesis1 and are what comprise the family unit, the decline of which is eroding the values given by God. (shrink)

This essay argues that in overlooking the assault on the autonomy, unity, and tenacity of the classical world underway in Europe after 1880, historians have failed to appreciate an important element of historiographical reorientation at the fin de siècle. This second "revolution" in humanistic scholarship challenged the conviction of the educated elite that European culture was rooted exclusively in classical antiquity in part by introducing as evidence non-textual forms of evidence; the testimony of artifacts allowed writers to reach beyond romantic-nationalist (...) histories toward the identification of cultural areas, defined by morphological similarities, and to disrupt the traditional categories of the civilized and the barbaric. The essay focuses on a relatively obscure Austrian art historian, Josef Strzygowski, whose insistence upon Europe's dependence on Oriental forms and upon the superior historical value of material, over textual, evidence provided critics of philologically-based humanism with two important argumentative avenues. Strzygowski also represents a para-academic type, whose rise to power and prestige contributed to the so-called "decline of the German mandarins." In sketching his career, the essay attempts to show how this "decline" is bound up with the waning institutional and popular status of Renaissance humanism--and a corresponding rise of biologistic Germanophilia--in the two intellectual milieux Strzygowski inhabited . A final section suggests that this antihumanist crusade contributed not only to the articulation of racist historiography, but also to the eventual transference of politico-moral legitimacy to a non-elitist, anthropological definition of culture. (shrink)

When fcc single crystals with high-symmetry crystal orientations are deformed to moderate strains by rolling, tension or channel die compression, long dislocation boundaries inclined to the extension axis form. Similarly, long dislocation boundaries are often found in grains embedded in polycrystals deformed in the same manner. These extended planar boundaries are characteristically - 30-40° from the extension direction and contain the transverse specimen axis. The objective of the present article is to demonstrate that EPBs formed during plane strain deformation are (...) parallel to equivalent slip planes, a pair of hypothetical slip systems used for analyses of the strain and crystal rotation components in place of the larger number of physical slip systems. The coincidence of EPBs and equivalent slip plane inclinations is shown to account for persistent observations of EPBs in the angle range - 30-40° from the rolling direction, in rolled single crystals of various initial orientations. The tendency of EPBs towards tilt or twist boundary character can also be rationalized on the basis of the equivalent slip system concept and consideration of the dislocation types available to be incorporated into EPBs. (shrink)

This article presents an overview ofregulations, guidelines and societal debates ineight member states of the EC about a)embryonic and fetal tissue transplantation(EFTT), and b) the use of human embryonic stemcells (hES cells) for research into celltherapy, including `therapeutic' cloning. Thereappears to be a broad acceptance of EFTT inthese countries. In most countries guidance hasbeen developed. There is a `strong' consensusabout some of the central conditions for `goodclinical practice' regarding EFTT.International differences concern, amongstothers, some of the informed consent issuesinvolved, and the (...) questions whether anintermediary organisation is necessary, whetherthe methods of abortion may be influenced bythe possible use of EFT, and whether EFTTshould only be used for the experimentaltreatment of rare disorders. The potential useof hES cells for research into cell therapy hasgiven a new impetus to the debate about (human)embryo research. The therapeutic prospects withregard to the retrieval and research use of hEScells appear to function as a catalyst for theintroduction of less restrictive regulationsconcerning research with spare embryos, atleast in some European countries. It remains tobe seen whether the prospect of treatingpatients suffering from serious disorders withtransplants produced by therapeutic cloningwill decrease the societal and moral resistanceto allowing the generation of embryos for`instrumental' use. (shrink)

Name der Zeitschrift: Das Mittelalter Jahrgang: 19 Heft: 2 Seiten: 407-419.

The paper argues that an adequate account of Nietzsche's conception of value must take into consideration the complex interaction of intrahuman forces, such as drives and affects, and interhuman cultural forces which together give rise to values. The paper goes on to confront three major interpretive tendencies in Nietzsche scholarship which stem, I argue, from overly reductive accounts of value. The tendencies, exemplified by Richard Schacht, Maudmarie Clark, and Alexander Nehamas respectively claim: that value is or should be objective (...) in character, that value claims are reliant on consistent with truth claims, and that value is realized most highly in individual lives. On the basis of the conception of value articulated, the paper ultimately defends the view that value, for Nietzsche, is intra- and intersubjective in its origins, non-cognitive in character, and realized most importantly as the cultural, rather than individual, level.Im Beitrag wird gezeigt, dass eine angemessene Darstellung von Nietzsches Wertkonzept die komplexe Wechselwirkung von solchen Kräften, die im Menschen selbst zu finden sind, wie Triebe und Affekte, und zwischenmenschlichen kulturellen Kräften, die im Menschen selbst zu finden sind, wie Triebe und Affekte, und zwishcenmenschlichen kulturellen Kräften, die im Menschen selbst zu finden sind, wie Triebe und Affekte, und zwischenmenschlichen kulturellen Kräften berücksichtigen muss. Es werdent drei einflussreiche Interpertationslinien in der gegenwärtigen Nietzscheforschung, vertreten durch Richard Schacht, Maudmarie Clark und Alexander Nehamas, gegenübergestellt, die, wie ich meine, von einem allzu reduzierten Ansatz hinsichtlich des Wertes ausgehen, indem behaptet wirt: dass Werte objektiv sind oder sein sollen, dass Wertansprüche abhängig sind von oder konsistent sind mit Warheitsansprüchen, dass Werte vor allem im individuellen Leben realisiert werden. Der Beitrag stellt dagegen, dass Werte für Nietzsche ihrem Ursprung nach intra- und intersubjektiv sind, ihrem Charakter nach nonkognitiv und eher auf der kulturellen als der individuellen Ebene realisiert werden. (shrink)

In this paper I discuss the managerial template that has become the normative model for the organization of the university. In the first part of the paper I explain the corporatization of academic life in terms of the functional relationships that make up the organizational components of the commercial enterprise and their inappropriateness for the life of the academy. Although there is at present a significant body of literature devoted to this issue, the goal of this paper is to explain (...) the genesis of this phenomenon through a reference to the ideology that characterizes our modern secular age. This is the subject of the second part of the paper. Most texts seek to explain this ideological development either through the ever increasing dominance of economic rationalism, perceived conservatism of collegial forms of governance, the necessity to transfer fiscal responsibility in tight budgetary periods, the decline of the Keynesian ‘welfare consensus’, or the legacy of the power regimes that began to take shape in the liberal societies of the 19th century. I trace this development to the beginnings of Modernity and the Cartesian bifurcation that separated the material world from its spiritual and intellectual source and thereby overthrew the hierarchy of related values that informed both nature and human organization. In articulating this argument I make reference to the thought of Jacques Maritain, Charles Taylor and René Guénon. (shrink)

In this article we address Emile Durkheim's theory that norms and values become more generalized and abstract in a society as it becomes more complex and differentiated. To test Durkheim's theory we examine etiquette manuals—the common texts that define normative manners and morals in American society. We perform a deductive content analysis on past and present etiquette manuals to understand what changes have occurred regarding shifting behavioral norms and values over time. Our findings suggest that a change has (...) occurred in the presentation and language of contemporary etiquette manuals, reflecting a greater change in the normative order. We find—as Durkheim would expect—that three main shifts have occurred: a shift from specific to general expectations for behavior in social settings, a shift from demanding to more suggestive rules of behavior in social situations, and a weakening in the severity of sanctions for breaches of etiquette. (shrink)

Recent scholarship has focused on the tensions, contradictions, and limits of place-based branding through labels of origin, place-named agricultural products, and geographical indications. Existing literature demonstrates that even well-intentioned efforts to use place-based branding to protect the livelihoods and cultural and ecological practices of small producers are often undermined by transnational firms, states, and local elites who attempt to capture the benefits of these marketing strategies. Yet, little attention has been given to the implications of place-based branding for competition among (...) geographically dispersed agricultural producers. While place-based branding can be used for emancipatory ends, it can also be used strategically by agricultural producers to expand their market share at the expense of others. To explore these dynamics, I trace an alternative history of place-based branding that begins not in the potentially emancipatory politics of protecting terroir but rather in the tensions and contradictions characterizing the rise and decline of the US food regime. Drawing on a cross-time comparison of branding strategies within the global cotton trade, I make two key arguments. First, I argue that US producers and the US state forged the use of different types of branding strategies in response to the distinct tensions and contradictions characterized by the rise and decline of the US food regime. Second, these distinct branding strategies organized competition among geographically dispersed cotton producers in different ways. (shrink)