Ben shu yi Wang Yangming di zi Zou Dongkuo wei yan jiu dui xiang, zhuo zhong tan tao qi si xiang jie gou he nei han, bing jiang dui qi ge ti zhe xue si xiang de yan jiu na ru dao zheng ge Yangming xue fen hua, yan bian de li shi jin cheng zhong lai que ding qi ge ti de si xiang shi ding wei, jie yi kao cha qi ge ti de si xiang te se he (...) zheng ge Yangming xue zai zhong wan Ming de fa zhan te dian. (shrink)

DNA replication stress threatens ordinary DNA synthesis. The evolutionarily conserved DNA replication stress response pathway involves sensor kinase Mec1/ATR, adaptor protein Mrc1/Claspin, and effector kinase Rad53/Chk1, which spurs a host of changes to stabilize replication forks and maintain genome integrity. DNA replication forks consist of largely distinct sets of proteins at leading and lagging strands that function autonomously in DNA synthesis in vitro. In this article, we discuss eSPAN and BrdU‐IP‐ssSeq, strand‐specific sequencing technologies that permit analysis of protein localization and (...) DNA synthesis at individual strands in budding yeast. Using these approaches, we show that under replication stress Rad53 stalls DNA synthesis on both leading and lagging strands. On lagging strands, it stimulates PCNA unloading, and on leading strands, it attenuates the replication function of Mrc1‐Tof1. We propose that in doing so, Rad53 couples leading and lagging strand DNA synthesis during replication stress, thereby preventing the emergence of harmful ssDNA. (shrink)

Hume's Epistemological Evolution argues that Hume's Enquiry represents a significant departure from the Treatise in respect of its epistemological framework. The Treatise's treatment of skepticism is an unsatisfactory one, as Hume seems to realize, and he therefore forms a new epistemological framework in the Enquiry. Qu's central argument is that Hume's epistemology evolves between these two works.

The quality and quantity of training data are crucial to the performance of a deep-learning-based brain-computer interface system. However, it is not practical to record EEG data over several long calibration sessions. A promising time- and cost-efficient solution is artificial data generation or data augmentation. Here, we proposed a DA method for the motor imagery EEG signal called brain-area-recombination. For the BAR, each sample was first separated into two ones by left/right brain channels, and the artificial samples were generated by (...) recombining the half-samples. We then designed two schemas corresponding to the single- and multi-subject scenarios. Extensive experiments using the classifier of EEGnet were conducted on two public datasets under various training set sizes. In both schemas, the BAR method can make the EEGnet have a better performance of classification. To make a comparative investigation, we selected two common DA methods, and the BAR method beat them. Further, using the proposed BAR for augmentation, EEGnet achieved up to 8.3% improvement than a typical decoding algorithm CSP-SVM, note that both the models were trained on the augmented dataset. This study shows that BAR usage can significantly improve the classification ability of deep learning to MI-EEG signals. To a certain extent, it may promote the development of deep learning technology in the field of BCI. (shrink)

This article investigates Hume's account of mental transparency. In this article, I will endorse Qualitative Transparency – that is, the thesis that we cannot fail to apprehend the qualitative characters of our current perceptions, and these apprehensions cannot fail to be veridical – on the basis that, unlike its competitors, it is both weak enough to accommodate the introspective mistakes that Hume recognises, and yet strong enough to make sense of his positive employments of mental transparency. Moreover, Qualitative Transparency is (...) also philosophically satisfying in providing good philosophical reason for why the mental states that are incorrigible should in fact be so. (shrink)

The approximate number system (ANS) enables organisms to represent the approximate number of items in an observed collection, quickly and independently of natural language. Recently, it has been proposed that the ANS goes beyond representing natural numbers by extracting and representing rational numbers (Clarke & Beck, 2021a). Prior work demonstrates that adults and children discriminate ratios in an approximate and ratio-dependent manner, consistent with the hallmarks of the ANS. Here, we use a well-known “connectedness illusion” to provide evidence that these (...) ratio-dependent ratio discriminations are (a) based on the perceived number of items in seen displays (and not just non-numerical confounds), (b) are not dependent on verbal working memory, or explicit counting routines, and (c) involve representations with a part-whole (or subset-superset) format, like a fraction, rather than a part-part format, like a ratio. These results vindicate key predictions of the hypothesis that the ANS represents rational numbers. (shrink)

College students have gradually become the main force of entrepreneurship in mass entrepreneurship and innovation. However, their entrepreneurial performance was not as good as expected. We have carried out research to analyze the predictive factors of entrepreneurial performance of college students and put forward targeted suggestions, hoping to be helpful to improve their entrepreneurial performance of them. Based on questionnaire data obtained from 2,097 college student entrepreneurs, this study uses the structural equation model to analyze the predictive factors of the (...) entrepreneurial performance of college students. The survey results of the questionnaire show that both personal and behavioral factors influence the entrepreneurial performance of college students. In this study, personal factors in this study mainly include entrepreneurial willingness, personality, and ability of entrepreneurs. Behavioral factors mainly refer to the positive behaviors of entrepreneurs that can affect entrepreneurial performance. (shrink)

Hume views the passions as having both intentionality and qualitative character, which, in light of his Separability Principle, seemingly contradicts their simplicity. I reject the dominant solution to this puzzle of claiming that intentionality is an extrinsic property of the passions, arguing that a number of Hume’s claims regarding the intentionality of the passions (pride and humility in particular) provide reasons for thinking an intrinsic account of the intentionality of the passions to be required. Instead, I propose to resolve this (...) tension by appealing to Hume’s treatment of the ‘distinctions of reason’, as explained by Garrett (1997). (shrink)

Hume often praises and appeals to the theoretical virtue of simplicity in his philosophy. Yet there has been relatively little scholarship done on Hume’s conception of theoretical simplicity. This paper will look to rectify this lacuna in the literature. In particular, it will look to answer three questions as they relate to Hume’s philosophy. First, what is theoretical simplicity? Second, why should we favour simpler theories over more complex ones? Third, can a theory be too simple, and if so, how?The (...) paper will argue that for Hume, theoretical simplicity concerns the causal explanation of phenomena in terms of the fewest possible causes. Second, simplicity has both epistemic and aesthetic value for Hume. While he does not follow his contemporaries in appealing to God to justify the truth-conduciveness of theoretical simplicity, some of his discussions of this virtue include elements suggestive of a meta-inductive justification of it. In addition, Hume also sees theoretical simplicity as having an intrinsic aesthetic value over and above its epistemic merit. Third, Hume recognises that there are both epistemic and aesthetic tradeoffs involved with theoretica lsimplicity, which might rule against an overly simple theory. (shrink)

Disputants in the debate regarding whether Hume's argument on induction is descriptive or normative have by and large ignored Hume’s positive argument (that custom is what determines inferences to the unobserved), largely confining themselves to intricate debates within the negative argument (that inferences to the unobserved are not founded on reason). I believe that this is a mistake, for I think Hume’s positive argument to have significant implications for the interpretation of his negative argument. In this paper, I will argue (...) that Hume’s positive and negative arguments should be read as addressing the same issues, whether normative or causal. I will then focus on the Enquiry version of Hume’s positive argument, arguing that it carries a significant normative conclusion: there, Hume argues that custom plays a normative role in justifying our inductive inferences. Given that Hume’s positive argument should be read as addressing the same issues as his negative argument, we should correspondingly read Hume’s negative argument in the Enquiry as having a normative conclusion. (shrink)

With the rapid development of computer science and information technology, artificial intelligence has been developed from theory to application. As a key technology in the modern society, AI is increasingly affecting all aspects of people’s daily lives, including sports training. AI can be considered as an assistive technology to provide specific support to athletes’ physical education training through various means such as data analysis and simulation of training scenarios. Although research on AI is still in the preliminary stage, it is (...) significant to explore how AI can be applied in sports training since this emerging technology could facilitate people’s physical training to some extent. This paper first reviews the existing research on AI applications. Then, based on the fundamental concept and related research results of AI, this study explores three specific cases of AI application in sports training and explains the main principles. This research focuses on discussing the strong relationship between AI technology and physical education training and highlights the advantages of AI, including utilization, convenience, and innovation. (shrink)

The inoffensive title of Section 1.4.7 of Hume’s Treatise of Human Nature, ‘Conclusion of this Book’, belies the convoluted treatment of scepticism contained within. It is notoriously difficult to decipher Hume’s considered response to scepticism in this section, or whether he even has one. In recent years, however, one line of interpretation has gained popularity in the literature. The ‘usefulness and agreeableness reading’ (henceforth U&A) interprets Hume as arguing in THN 1.4.7 that our beliefs and/or epistemic policies are justified via (...) their usefulness and agreeableness to the self and others; proponents include Ardal (in Livingston & King (eds.) Hume: a re-evaluation, 1976), Kail (in: Frasca-Spada & Kail (eds.) Impressions of Hume, 2005), McCormick (Hume Stud 31:1, 2005), Owen (Hume’s reason, 1999), and Ridge (Hume Stud 29:2, 2003), while Schafer (Philosophers, forthcoming) also defends an interpretation along these lines. In this paper, I will argue that although U&A has textual merit, it struggles to maintain a substantive distinction between epistemic and moral justification—a distinction that Hume insists on. I then attempt to carve out the logical space for there being a distinctly epistemic notion of justification founded on usefulness and agreeableness. However, I find that such an account is problematic for two reasons: first, it cannot take advantage of the textual support for U&A; secondly, it is incompatible with other features of the text. (shrink)

In this paper, I examine three mutually inconsistent claims that are commonly attributed to Hume: all beliefs are involuntary; some beliefs are subject to normative appraisal; and that ‘Ought implies Can’. I examine the textual support for such ascription, and the options for dealing with the puzzle posed by their inconsistency. In what follows I will put forward some evidence that Hume maintains each of the three positions outlined above. I then examine what I call the ‘prior voluntary action’ solution. (...) I argue that this position in any form fails to account for synchronic rationality. I then raise more specific objections depending on how we disambiguate the position, which can be read as either granting beliefs derivative voluntariness, or as denying their normative significance; the former version is inconsistent with Hume’s treatment of natural abilities, while the latter falls to a regress given Hume’s thesis regarding the inability of actions and passions to be subject to epistemic normativity. I then propose to reject instead for two reasons: first, the weakness of textual support for such an ascription; secondly, Hume’s explicit recognition of the irrelevance of involuntariness to normative evaluation in the moral case. (shrink)

Much has been written about Kemp Smith's famous problem regarding the tension between Hume's naturalism and his scepticism. However, most commentators have focused their attention on the Treatise; those who address the Enquiry often take it to express essentially the same message as the Treatise. When Hume's scepticism in the Enquiry has been investigated in its own right, commentators have tended to focus on Hume's inductive scepticism in Sections 4 and 5. All in all, it seems that Section 12 has (...) been unduly neglected. This paper seeks to address Kemp Smith's problem from the standpoint of Hume's treatment of scepticism in EHU 12, and finds an interesting internalist account that makes sense both of Hume's discussion in EHU 12, and his aims in the Enquiry as a whole. Moreover, it is one that is of substantive philosophical interest, having intriguing parallels to contemporary epistemological accounts. (shrink)

Taguergoust (Morocco), history; Cities and towns; Morocco; history.

Discussion on whether Hume's treatment of induction is descriptive or normative has usually centred on Hume's negative argument, somewhat neglecting the positive argument. In this paper, I will buck this trend, focusing on the positive argument. First, I argue that Hume's positive and negative arguments should be read as addressing the same issues . I then argue that Hume's positive argument in the Enquiry is normative in nature; drawing on his discussion of scepticism in Section 12 of the Enquiry, I (...) explain a framework by which he provides what I call consequent justification for our inductive practices in his positive argument. Based on this, I argue that his negative argument in the Enquiry should similarly be read as normative in nature. (shrink)

Hume argues that whenever we seem to be motivated by reason, there are unnoticed calm passions that play this role instead, a move that is often criticised as ad hoc. In response, some commentators propose a conceptual rather than empirical reading of Hume’s conativist thesis, either as a departure from Hume, or as an interpretation or rational reconstruction. I argue that conceptual accounts face a dilemma: either they render the conativist thesis trivial, or they violate Hume’s thesis that ‘a priori, (...) any thing may produce any thing’. I defend an empirical construal of Hume’s conativist thesis. I provide two theoretical frameworks within which Hume’s appeal to the calm passions may be justified: first, by the framework of theoretical virtues, and secondly, by lights of his own “rules by which to judge of causes and effects”. (shrink)

Commentators such as Kemp Smith (1941), Mendelbaum (1974), and Bricke (1980) have taken the distinctions of reason to pose either a counterexample to or a limitation of scope on the Separability Principle. This has been convincingly addressed by various accounts such as Garrett (1997), Hoffman (2011), and Baxter (2011). However, I argue in this paper that there are two notions of ‘distinction of reason’, one between particular instantiations (token distinctions of reason) and one between general ideas (type distinctions of reason). (...) Discussion of the distinctions of reason in the secondary literature has without fail focused on token distinctions of reason, but I will argue that type distinctions of reason prove problematic for Hume’s Separability Principle. I find a way around this problem that is consonant with Hume’s account of general ideas, but which can hardly be said to be an account which he explicitly or even implicitly endorsed. (shrink)

There seems a potential tension between Hume's naturalistic project and his normative ambitions. Hume adopts what I call a methodological naturalism: that is, the methodology of providing explanations for various phenomena based on natural properties and causes. This methodology takes the form of introducing ‘the experimental method of reasoning into moral subjects’, as stated in the subtitle of the Treatise; this ‘experimental method’ seems a paradigmatically descriptive one, and it remains unclear how Hume derives genuinely normative prescriptions from this methodology. (...) In resolving this problem, I will argue that Hume's naturalistic methodology – that is, his ‘experimental philosophy’, or what has come to be known as his experimental method – consists of the systematization of phenomena pertaining to human nature. In applying his experimental method to normative subjects, Hume systematizes our normative judgements, deriving general principles of normative justification; he then reflexivel... (shrink)

Although there is consensus that authentic leaders act according to their true values, we have no empirical evidence of what specific values authentic leaders have. While traditional leadership approaches place power at the core of leadership, authentic leadership scholars would argue that benevolence is the value that is central to effective authentic leadership. To date, the questions about whether and when authentic leaders with high power values promote or hurt followers’ performance have not been investigated. Ostensibly, authentic leaders with high (...) power values seem to represent the dark side of authentic leadership. In this paper, we develop a theoretical model and empirically investigate the role that leaders’ power values play in the functioning of authentic leadership. We also test the assumption that authentic leaders with high benevolence values promote followers’ performance. Based on our multilevel analyses of 477 employees in 72 teams, we found that authentic leaders with prominent power values could foster followers’ performance, only when followers’ perceived value congruence was low. Authentic leaders with high benevolence values, however, cultivated followers’ performance unconditionally, regardless of perceived value congruence levels. (shrink)

In this paper, I will argue that a number of Hume’s claims generate a putative inconsistency with regard to complex ideas and independent existence. I first provide a prima facie argument for the existence of this inconsistency. Then, I examine a number of attempts to rescue Hume from this problem, and argue that each of them fails, before proposing my own solution.

In this paper, I argue for an interpretation of Hume's Law that sees him as dismissing all possible arguments from is to ought on the basis of a comparison with his famous argument on induction.

صدر عن المركز العربي للأبحاث ودراسة السياسات كتاب زهير قوتال "المفهوم الفلسفي عند جيل دولوز"، الذي ينظر فيه إلى جيل دولوز بصفته فيلسوفًا شديد الفضول، يهتم بكل ما يشكله حاضره وينتجه عصره؛ إذ وجه جلّ فكره نحو القبض على مساحة حدْثية مرآوية، طاويًا سحر كتابته لتجاوز الأماكن الفارغة من المعنى. وقع الاختيار على المفهوم الفلسفي عنده لأنه أكثر الفلاسفة اشتغالًا على المفاهيم الفلسفية، من خلال حواراته مع كبار الفلاسفة.

Hume argues that whenever we seem to be motivated by reason, there are unnoticed calm passions that play this role instead, a move is that is often criticised as ad hoc (e.g. Stroud 1977 and Cohon 2008). In response, some commentators propose a conceptual rather than empirical reading of Hume’s conativist thesis, either as a departure from Hume (Stroud 1977), or as an interpretation or rational reconstruction (Bricke 1996). -/- I argue that conceptual accounts face a dilemma: either they render (...) the conativist thesis trivial, or they violate Hume's thesis that 'a priori, any thing may produce any thing'. I defend an empirical construal of Hume’s conativist thesis. I provide two theoretical frameworks within which Hume’s appeal to the calm passions may be justified: first, by the framework of theoretical virtues, and secondly, by lights of his own ‘rules by which to judge of causes and effects’ (THN 1.3.15). (shrink)