This paper critically compares the philosophy of Günther Anders and the contemporary transhumanists, like Julian Savulescu, Ingmar Persson, or Thomas Douglas. The Andersian concepts of moral blindness, promethean gap, and promethean shame will be discussed in order to understand human beings’ outdatedness; parallel to this, we will also expose the transhumanist analysis on the unfitness of human beings in evolutive and cognitive terms. We will show that much of the transhumanist analysis is a reformulation of the Andersian thesis, now under (...) scientific terminology. Finally, we will approach the transhumanist proposal of moral enhancement, explaining and confronting some critics raised on the grounds of freedom and moral responsibility. (shrink)
RNA editing is a major post-transcriptional mechanism that changes specific nucleotides at the RNA level. The most common RNA editing type in humans is adenosine to inosine editing, which is mediated by ADAR enzymes. RNA editing events can not only change amino acids in proteins, but also affect the functions of non-coding RNAs such as miRNAs. Recent studies have characterized thousands of miRNA RNA editing events across different cancer types. Importantly, individual cases of miRNA editing have been reported to play (...) a role in cancer development. In this review, we summarize the current knowledge of miRNA editing in cancer, and discuss the mechanisms on how miRNA-related editing events modulate the initiation and progression of human cancer. Finally, we discuss the challenges and future directions of studying miRNA editing in cancer. RNA editing is introduced by ADAR or APOBEC enzymes, leading to specific nucleotide changes, respectively. The interplays between RNA editing and miRNAs may play important roles in cancer. This graphical abstract shows four major mechanisms through which miRNAs interact with RNA editing to confer a functional impact on tumor development. (shrink)
This paper investigates the representation of the Shijing 詩經 and its hermeneutic traditions in Cao Zhi’s 曹植 poetic writings with regard to the reception and utilization of the Shijing at different stages, especially the early third century CE. Cao Zhi not merely appropriated poetic utterances and literary patterns from particular odes but also presented a variety of Shijing-related interpretations, which show correspondences with different hermeneutic traditions that transcended the boundaries of the four main Shijing schools. This case represents a syncretic (...) mode of the reception and utilization of the Shijing within larger intellectual and cultural contexts. The Cao regime, as the new ruling authority in Northern China around the early third century CE, engaged in gathering dispersed literary scholars and cultural legacies, in which the Shijing-related materials and sources played significant roles. Taking Cao Zhi’s syncretic representation of the Shijing and its hermeneutic traditions as an instantiation of these factors, this paper also aims to invite methodological reflections on the traditional and modern studies of the reception of the Shijing, considering its status with both literal significance and hermeneutic diversity in early and medieval China. (shrink)
Im 18. Jahrhundert bestand ein uberraschend grosses Interesse am Denker, Schriftsteller und Menschen David Hume (1711-1776), das die ganze Vielheit in den Voraussetzungen und Zielen der deutschen Aufklarung widerspiegelt. Zunachst standen die religionsphilosophischen Thesen Humes im Vordergrund; sie wurden durchweg abgelehnt und haufig nur polemisch zuruckgewiesen. Gerade als sich die Chance einer sachgerechteren Beurteilung Humes bot, revolutionierte Kant die gesamte Philosophie, und Hume wurde nur noch als der auslosende Faktor der Kantischen Metaphysikkritik gesehen. Die umstrittene Frage, wann und durch welches (...) seiner Werke Hume Kants dogmatischen Schlummer unterbrach, wird zur Entscheidung gebracht und damit zugleich eine neue These zu Kants philosophischer Entwicklung prasentiert. In the 18th century there was a surprisingly large amount of interest in the thinker, author and human being David Hume (1711-1776), and this interest reflected the entire range of requirements and goals of the German Enlightenment. To begin with, the focus was on Humes theories of the philosophy of religion, theories which were rejected without exception and often only polemically repudiated. Just when there was a chance of having an objective assessment of Humes work, Kant revolutionized philosophy, and Hume was seen merely as the factor which triggered Kants metaphysics. The controversial question of when and in which of his works Hume interrupted Kant's dogmatic slumber is brought to a head, and thus at the same time a new theory pertaining to Kant's philosophical development is presented. (shrink)
The Zhouyi is the first of the Chinese classics and has, since medieval times, fascinated scholars from different parts of the world, who have produced numerous studies and expressed a dazzling array of views on its nature. It is argued that the Zhouyi has retained its exalted status and enduring appeal largely because it is an open book amenable to all kinds of appropriations and manipulations, and its openness comes from its being a semiotic system whose principle of composition warrants (...) unlimited interpretations. Through a semiotic-cum-philosophical inquiry, it is shown that the Zhouyi is first and foremost a system of representation, and because of its unique structure and principle of signification it forms an open hermeneutic space with infinite possibilities of interpretation. (shrink)
Investigating how people respond to and view AI-created artworks is becoming increasingly crucial as the technology’s current application spreads due to its affordability and accessibility. This study examined how AI art alters people’s evaluation, purchase intention, and collection intention toward Chinese-style and Western-style paintings, and whether art expertise plays a role. Study 1 recruited participants without professional art experience and found that those who made the paintings would not change their liking rating, purchase intention, and collection intention. In addition, they (...) showed ingroup preference, favoring Chinese-style relative to Western-style paintings, in line with previous evidence on cultural preference in empirical aesthetics. Study 2 further investigated the modulation effect of art expertise. Art experts evaluated less favorably AI-generated paintings relative to artist-made paintings, while non-experts showed no preference. There was also an interaction effect between the author and the art expertise and interaction between the painting style and the art expertise. Collectively, the findings in this study showed that who made the art matters for experts and that the painting style affects aesthetic evaluation and ultimate reception of it. These results would also provide implications for AI-art practitioners. (shrink)
This article discusses the experience of an Icelandic woman with intellectual disabilities who was sterilized and how she has dealt with it. It also reflects on some ethical and methodological issues that arise during inclusive life history research. The article is based on cooperation between two women, Eygló Ebba Hreinsdóttir, who was labelled with intellectual disabilities when she moved to an institution in Iceland in the 1970s, and the researcher Gu?rún V. Stefánsdóttir. Since 2003 we have worked closely together on (...) an inclusive life history project. The article is based on a recorded conversation between Ebba and Gudrun and the work of the Icelandic women's history group in which both participated for three years. Ebba was sterilized when she was 14 years old but didn't know about the sterilization until she was 27. The article describes the deep emotional impact and how she came to terms with it. (shrink)
It could be said that chinese aesthetics merges together three cornerstones of the western tradition. It might be intended as the study of beauty in the Platonic sense, because of the vaste debate on the topic rooted back in chinese’s ancient times; it could match the sense of aesthetics as intended by Baumgarten, because of the long tradition of chinese perceptual studies, and it may also be compared to the Hegelian philosophy of art, given the abundance of chinese artistic manufacts (...) and theories. Chinese aesthetics is distinctive and very different from the western one. While the latter tries to grasp the inner beauty of things by breaking them and accounts for beauty as an object, chinese aesthetics considers beauty as a subject, rather aiming at feeling the beauty of things for what they are. Compared to the occidental tradition, which is rooted in sensation but deviates from sensation to pursue a rational goal, chinese aesthetics originates from the sensation and adheres to it all the time. Therefore, the chinese stance makes for a unique and genuine approach to the discipline. (shrink)
This paper aims at offering a new disjunctivist solution – anomalous disjunctivism – to the screening-off problem. Anomalous disjunctivism focuses on the necessary causal conditions for perception and hallucination. It argues that the proximate cause is contingent on causing a particular kind of sensory experience that can either be perceptual or hallucinatory. It further shows that the perceived thing is a necessary causal condition for perceptual experience and the failure of perception is a necessary causal condition for the hallucinatory counterpart. (...) It is the case that any account of a hallucinatory experience relies on the nature of hallucination, and, therefore, the anti-naïve realist has to agree that the necessary causal condition matters. As a consequence, whatever account we take for a hallucination, it need not apply to its perceptual counterpart. The screening-off problem, thereby, is dissolved. (shrink)
In this article, drawing from a relational perspective, we explore the relationship between moral leadership and employee creativity, treat employee identification with leader and leader–member exchange as two mediators, and develop a new theoretical model of employee creativity. Our data collected from 160 supervisor–subordinate dyads in the People’s Republic of China demonstrate that moral leadership is positively related to both employee identification with leader and LMX. Further, employee identification with leader partially mediates the relationship between moral leadership and LMX. In (...) particular, employee identification with leader greatly enhances LMX which leads to high creativity. Overall, the relationship between moral leadership and employee creativity is mediated by not only employee identification with leader but also LMX. Our findings offer a new theoretical framework for future theory development and testing on creativity as well as practical implications for researchers and managers in business ethics. (shrink)
The reasons conception is the most prominent account of the nature of critical thinking. It consists in responding appropriately to reasons. Responding to reasons can be following a rule, it can be making an exception to a rule, it can be responding to a situation that is unique. It depends on the context each time what is the appropriate response. Critical thinking is the educational cognate of rationality and is a sine qua non for a reasonable life in a modern (...) democratic society. Reasons are generally normative. If this is true then it is to be expected that critical thinking is normative and also rationality. Critical thinking consists in being appropriately moved by reasons. The normative element of reasons moves us to beliefs or actions. It depends on our character how reasons move us. This indicates that our character must be well formed to enable us to be appropriately moved. (shrink)
At that time [around 1916-17—Ed.], Cai Jiemin [Cai Yuanpei—Ed.] took office as president of Beijing University, and directed his efforts at breaking away from the school's stale and decayed atmosphere. The Xin qingnian zazhi operated by Chen Duxiu had ideological revolution as its main objective, and gradually drew the attention of the general public. And there was also the article entitled "Guoren zhi gongdu", published by Huang Yuanyong in Dongfang zazhi, which very bitterly castigated the roots of the maladies in (...) China's ideological and academic circles. I was very much emboldened by the many unexpected views I encountered—views similar to my own haughty views that I had always kept well hidden. Although I had ventured to offer a few criticisms in the past, I was daunted by the oppressive force of traditional ideology, and I thought that the words of the ancients were perhaps not as simple as they appeared to me, or that there indeed were fallacies or errors in my observations. For instance, when I was taking exams at the Cun gu xuetang, and received a comment by the examinations official that "It is wrong to reproach Zheng [Xuan]"; I was constantly taking note of Zheng Xuan's fallacies, but I always felt a sort of respect for him … or [thought that] there were aspects about him that deserved respect but that these aspects had somehow escaped my attention. By this time, however, everyone was advocating ideological innovation. I myself began to acquire a perception of the need to get rid of old ways of thinking. I realized that it was precisely because scholars of the Qing dynasty had been bound by the old ideology of believing the ancients and venerating tradition that they had never dared to smash the idol that was Zheng Xuan, although their learning was a thousand time superior to his, and the encumbrances created by that idol had hindered their work of seeking the truth. And so I began to voice criticisms with greater courage and boldness. (shrink)
This study explores the dark side of leadership, treats creative self-efficacy as a mediator, and frames supervisor bullying and employee creativity in the context of social cognition and social comparison. We theorize that with a high social comparison orientation, the combination of high supervisory abuse toward themselves and low supervisory abuse toward other team members leads to a double whammy effect: When employees are “singled out” for abuse, these victims suffer from not only low creative self-efficacy due to supervisory abuse (...) but also low supervisory creativity ratings. Results based on our two-wave data collected from multiple sources—253 employees and their 77 immediate supervisors—support our theory. The significant three-way interaction effect reveals that when social comparison orientation is high and peer abusive supervision is low, own abusive supervision creates the strongest negative impact on creative self-efficacy, which is significantly related to supervisory low creativity rating. Our discoveries of egregious bullying offer provocative theoretical, empirical, and practical implications to the fields of leadership, abusive supervision, creativity, and business ethics. (shrink)
Gu Yanwu, Record of Daily Knowledge and Collected Poems and Essays: Selections. Translated and edited by Ian Johnston. New York: Columbia University Press, 2017. Pp. xvii + 323. $75.
The time-lag argument seems to put some pressure on naïve realism to agree that seeing must happen simultaneously with what is seen; meanwhile, a wide-accepted empirical fact suggests that light takes time to transmit from objects at a distance to perceivers—which implies what is seen happened before seeing, and, accordingly, naïve realism must be false. In this paper, I will, first of all, show that the time-lag argument has in fact involves a misunderstanding concept of simultaneity: according to Special Relativity, (...) simultaneity is a matter of convention rather than a matter of fact, so, in principle, we can stipulate a perceptual conception of simultaneity, according to which what is seen is simultaneous with seeing. Secondly, the generalized time-lag argument has a mistaken view on the perceived events and perceiving; it has a doubtful assumption that these events are momentary in the mathematical sense. Such idealization is the main reason why we have the intuition that the time-lag effect of perceiving is in conflict with our ordinary perceptual experiences. Finally, I argue that the naïve realist account of the perceptual relation is a nontemporal constitutive relation; and hence naïve realism is compatible with the claim that we can perceive things as they were, and it should not be weakened by the time-lag argument. (shrink)
Customer civility is an established construct in the study of ethical consumption. However, scholars have paid insufficient attention to customer civility in relation to the flourishing peer-to-peer economy. Therefore, the purpose of this article is to develop and test a theoretical framework which examines the antecedents of the customer civility in the P2P economy. We use social exchange theory to develop a model that posits customer interaction experiences with property owners, properties, and P2P platforms as antecedents of customer civility in (...) the P2P economy. Two studies were used to test our framework: Study 1 comprises a survey of Chinese customers ; Study 2 involves secondary data crawled from the Web site of Xiaozhu, one of China’s largest P2P accommodation platforms. OLS regression analysis was used for hypothesis testing. Results demonstrate three antecedents of customer civility in the P2P accommodation sector: interpersonal trust, property experience, and platform governance. In addition, the positive effect of interpersonal trust on customer civility is stronger when customers have high economic incentive, while the effect of property experience is significantly stronger when customers have low economic incentive. (shrink)
A number of recent environmental philosophers have proclaimed the end of nature. They oppose what they consider to be an outdated view of nature as a basis for environmental philosophy and political ecology. Instead of “thinking like a mountain”, we should begin “thinking like a mall”. These end-of-nature thinkers claim that the concept of nature in environmental discourses is bound to be something that is outside of us because man is understood as doing something to nature. Without putting forth a (...) clearly defined concept of “nature,” we argue that proclaiming the end of nature is misguided. This proclamation means forgetting the body. If we really want to get beyond understanding nature as something outside of us, and truly sense and understand ourselves as natural or environmental beings who are a part of the earth’s ecosystem, we should direct our attention to how nature as the biotic, inner/outer environment is experienced and sensed in and through our bodies. We thus suggest that environmental philosophy should encourage sensing like embodied beings before introducing notions like thinking like a mountain, mall, water, or a plant for that matter. This approach is among other things based on the phenomemology of the body and phenomenology of the real.”. (shrink)
As the rising costs of lifestyle-related diseases place increasing strain on public healthcare systems, the individual’s role in disease may be proposed as a healthcare rationing criterion. Literature thus far has largely focused on retrospective responsibility in healthcare. The concept of prospective responsibility, in the form of a lifestyle contract, warrants further investigation. The responsibilisation in healthcare debate also needs to take into account innovative developments in mobile health technology, such as wearable biometric devices and mobile apps, which may change (...) how we hold others accountable for their lifestyles. Little is known about public attitudes towards lifestyle contracts and the use of mobile health technology to hold people responsible in the context of healthcare. This paper has two components. Firstly, it details empirical findings from a survey of 81 members of the United Kingdom general public on public attitudes towards individual responsibility and rationing healthcare, prospective and retrospective responsibility, and the acceptability of lifestyle contracts in the context of mobile health technology. Secondly, we draw on the empirical findings and propose a model of prospective intention-based lifestyle contracts, which is both more aligned with public intuitions and less ethically objectionable than more traditional, retrospective models of responsibility in healthcare. (shrink)
