Classic genetics studies found that genomic imbalance caused by changing the dosage of part of the genome (aneuploidy) has more detrimental effects than altering the dosage of the whole genome (ploidy). Previous analysis revealed global modulation of gene expression triggered by aneuploidy across various species, including maize (Zea mays), Arabidopsis, yeast, mammals, etc. Plant microRNAs (miRNAs) are a class of 20‐ to 24‐nt endogenous small noncoding RNAs that carry out post‐transcriptional gene expression regulation. That miRNAs and their putative targets are (...) preferentially retained as duplicates after whole‐genome duplication, as are many transcription factors and signaling components, indicates miRNAs are likely to be dosage‐sensitive and potentially involved in genomic balance networks. This review addresses the following questions regarding the role of miRNAs in genomic imbalance. (1) How do aneuploidy and polyploidy impact the expression of miRNAs? (2) Do miRNAs play a regulatory role in modulating the expression of their targets under genomic imbalance? (shrink)

Continuous environmental concerns regarding construction industry have been driving general constructors of mega infrastructure projects to incorporate green contractors. Although conventional multiple attributes decision-making methodologies have provided feasible ways to select contractor, high complexity in scenarios of megaprojects still challenges existing MADM methods in concurrently accommodating three key issues of decision hesitancy, attributes interdependency, and group attitudinal character. To elicit decision-makers’ hesitant fuzzy assessments more objectively and comprehensively, we define an expression tool called interval-valued dual hesitant fuzzy uncertain unbalanced linguistic (...) set and develop aggregation operators through its operations. To exploit attributes interdependency, we establish a synthesized attributes’ weighting model to fuse an attributes interdependency-based weighting vector and an argument-dependent weighting vector, which are, respectively, derived through Decision-Making and Trial Evaluation Laboratory technique and maximizing deviation method. To effectively utilize decision-makers’ group attitudinal characters, we also develop a TOPSIS-based method to rationally transform group ideal attitudes into order-inducing vectors. On the strength of the above methods, an integrated MADM approach is then constructed. Finally, illustrative case study and experiments are conducted to validate our approach. (shrink)

Individuals who are more easily disgusted tend to be more politically conservative. Individuals who have a preference for order also tend to be more politically conservative. In the present researc...

Some proponents of higher education English as a medium of instruction have suggested listening to English lectures provides students the opportunity to incidentally acquire unknown words. A case study was designed to examine this assumption. First, the lexical profiles of 27 Introduction to English Language Teaching first-year undergraduate course lectures were computed to determine how many words students need to know for comprehension. Then an incoming year-1 undergraduate student with an English vocabulary size of 7,500 word families and mastery of (...) the most frequent 3,000 word families listened to these lectures across 13.5 weeks with the purpose of measuring incidental acquisition gains of three aspects of word knowledge for ten targeted words. Lastly, the student’s perceptions about listening to EMI lectures and potentials for this listening inducing incidental acquisition of word knowledge were gathered through a semi-structured interview. The lexical profiling of the entire corpus showed students need knowledge of the most frequent 4,000 English word families plus proper nouns and marginal words for 98% lexical coverage; however, some lectures present students with a more substantial lexical burden than the lectures overall. The student made the most gains in receptive meaning, followed by receptive form, and finally productive meaning. Content analysis of the interview transcript found seven themes representing the student’s perception about listening to EMI lectures and their potential for inducing incidental vocabulary acquisition. While the student found listening to the EMI lectures challenging, he perceived the process as useful in preparing for university studies and a career as a secondary English teacher. The student perceived attention, topic, existing vocabulary knowledge, lecturer’s native language, and lack of interaction with the lecturer to have moderated incidental learning of vocabulary through listening to English lectures. These results indicate a need to confirm whether incoming students’ vocabulary knowledge meet the lexical demands of the EMI lectures given in the Macau context. Furthermore, pedagogical training on teacher talk strategies and orientation training for incoming students should both be provided to ensure students are receiving high quality instruction. (shrink)

胡適（1891-1962），安徽績溪人。原名嗣穈，後改名胡適，字適之，曾用筆名希彊、臧暉等。新文化運動的奠基人與領袖之一，倡導約翰・杜威的實用主義。1917年回國任教北大，參與編輯《新青年》《努力周報 》《獨立評論》等雜誌，先後擔任中華民國駐美大使、國立北京大學校長、台北「中央研究院」院長等職，著有《中國哲學史大綱》《嘗試集》《胡適文存》等書，並獲諾貝爾文學獎提名。.

As the autonomous vehicles technology gradually enters the public eye, understanding consumers' psychological motivations for accepting autonomous vehicles is critical for the development of autonomous vehicles and society. Previously, researchers have explored the determinants of fully autonomous vehicles but the relevant research is far from enough. Moreover, the relationship between anthropomorphism and users' behavior has been ignored to a large extent. Therefore, this study aim to fill the gap by using anthropomorphism and the unified theory of acceptance and use of (...) technology to explore how system attributes and UTAUT attributes influence consumers' acceptance behavior. The data were collected via questionnaire survey conducted in Beijing, China, which can be a promising early adopter of AVs. Structural equation modeling was used to analyze the data. The results reveal that perceived anthropomorphism and perceived intelligence have a direct positive influence on the adoption of AVs; performance expectancy, effort expectancy, and facilitating conditions have an indirect positive influence on intention to adopt AVs. Also, this research contributes to the literature by enriching studies on psychological determinants of autonomous vehicles' adoption by taking an initial step to highlight anthropomorphism perceptions. This can provide managerial implications for policy-makers and businesses on how to effectively allocate resources to enhance autonomous vehicle adoption. (shrink)

本书分为神话与诉讼,历史与诉讼,故事与诉讼,制度法理,学术争鸣,法学教育,治学人生等八辑,收录了剧与诉的随想,正义之舞,游戏与诉讼,圣殿骑士的死亡密码,走向刑事宪法,法官权力之源与品格之治,法国法学教 育三题,关问于山水之间等文章.

Finding meaning in our lives is a central tenet to the human experience and a core contributor to mental health. Individuals tend to actively seek the sources of meaning in their lives or consciously enact efforts to create or “craft” meaning in different life domains. These overall “Life Crafting” behaviors refer to the conscious efforts individuals exert to create meaning in their lives through cognitively framing how they view life, seeking social support systems to manage life challenges, and actively seeking (...) challenges to facilitate personal growth. Specifically, these behaviors are actioned to better align life goals, personal needs, values, and capabilities. However, no psychological assessment instrument currently exists to measure overall life crafting. As such, the purpose of this paper was twofold: to conceptualize life crafting and to develop, validate and evaluate a robust measure of overall life crafting. A mixed-method, multi-study research design was employed. First, nine participants were interviewed to determine the methods or techniques used to craft meaningful life experiences. These methods/techniques were used as indicators to create an initial item pool which was then reviewed by a panel of experts to ensure face validity. Second, in Study 1, the factorial structure of the instrument was explored by gathering data from a convenience sample, with the results showing support for a three-factor structure of life crafting, consisting of cognitive crafting, seeking social support, and seeking challenges. Finally, in Study 2, the aim was to confirm the factorial structure of the Life Crafting scale and to determine its level of internal consistency, partial measurement invariance across genders, and criterion validity [meaning in life, mental health, work engagement, and job burnout ]. The results supported a second-order factorial model of Life Crafting, which comprised of three first-order factors. Therefore, the Life Crafting Scale can be used as a valid and reliable instrument to measure- and track the effectiveness of life crafting interventions. (shrink)

Continuous environmental concerns regarding construction industry have been driving general constructors of mega infrastructure projects to incorporate green contractors. Although conventional multiple attributes decision-making methodologies have provided feasible ways to select contractor, high complexity in scenarios of megaprojects still challenges existing MADM methods in concurrently accommodating three key issues of decision hesitancy, attributes interdependency, and group attitudinal character. To elicit decision-makers’ hesitant fuzzy assessments more objectively and comprehensively, we define an expression tool called interval-valued dual hesitant fuzzy uncertain unbalanced linguistic (...) set and develop aggregation operators through its operations. To exploit attributes interdependency, we establish a synthesized attributes’ weighting model to fuse an attributes interdependency-based weighting vector and an argument-dependent weighting vector, which are, respectively, derived through Decision-Making and Trial Evaluation Laboratory technique and maximizing deviation method. To effectively utilize decision-makers’ group attitudinal characters, we also develop a TOPSIS-based method to rationally transform group ideal attitudes into order-inducing vectors. On the strength of the above methods, an integrated MADM approach is then constructed. Finally, illustrative case study and experiments are conducted to validate our approach. (shrink)

This paper introduces the Generalized Argumentation Theory which takes argumentation as a locally rational socio-cultural interaction governed by social norms and carried out through discourse between the members of a socio-cultural community in order to reason things out. Then we bring in the basic structure of generalized argumentation and the localized procedure of Generalized Argumentation Theory for studying the argumentative rules. On the basis of above introduction, we use the localized procedure to analyze a case of political argumentation by reciting (...) poems in ancient China. By doing so, it’s indicated that political argumentation by reciting poems, in essence, takes cultural principle of Li of the Spring and Autumn Period as argumentative rules and uses poems to express ideas, in virtue of which arguments are accepted as locally rational by the politicians at that time. At last, the Little Red Book quotation fight, a similar political activity, is discussed briefly to show the significance that ancient Chinese political argumentation has on contemporary argumentation. (shrink)

Positive psychology has received increasing attention in the field of education. Therefore, it would be of utmost importance to analyze the relationship between the constructs falling under the category of positive psychology and other constructs to pave the way for both educational authorities and teachers themselves. Reviewing the previous studies, it turned out that there have been no studies to discuss the interplay between teachers’ psychological capital and their job commitment and academic optimism particularly in the context of China. To (...) fill this gap, the current study set out to inspect the function of Chinese English as a Foreign language teachers’ psychological capital in promoting their job commitment and academic optimism. To accomplish this, 316 Chinese teachers were asked to complete “Psychological Capital Scale,” “Job Commitment Scale,” and “Academic Optimism Scale.” The results of regression analyses revealed that Chinese EFL teachers’ psychological capital can strongly predict their job commitment and academic optimism. The conclusion and implications of the results are finally discussed and it is mentioned that both educational authorities and teachers can benefit from this study and make the experience of teaching much more productive. (shrink)

In this article, we offer a critical realist conception of curriculum that aims to cultivate critical thinking (CT) and liberate students from egocentric rationality. We first examine egocentric rationality as a problem emerging from the technicist paradigm of cultivating CT in higher education, exemplified by issues arising from the pedagogical activity of debate. We then examine existing approaches to cultivating CT, focusing on the extent to which their goals and conceptions of CT could liberate students from egocentric rationality. Drawing on (...) Roy Bhaskar’s stratified conception of being and principle of immanent critique, we offer a critical realist conception of curriculum, explaining its definition of CT as the capacity for self-critique. We shall illustrate, in the context of an undergraduate debate course, how such capacity can be developed in order to liberate students from egocentric rationality. Curriculum is thus a critical praxis, a created space where student’s CT develops in a way that is intrinsically entwined with their being and becoming. This article extends the philosophical basis for integrating CT with curriculum and offers pedagogical implications. (shrink)

Euthanasia in China is gaining increasing acceptance among physicians, intellectuals, and even the people. This paper surveys current attitudes towards euthanasia and suggests why it should be legalized. Keywords: euthanasia, euthanasia in China CiteULike Connotea Del.icio.us What's this?

To explore the role of the social adaptability of different groups in human capital in an uncertain environment, this paper empirically tests the relationship between social adaptation and human capital by using a panel quantile regression model with the life satisfaction of 35 cities in China as an indicator. By selecting Nelder Mead and adaptive MCMC estimation methods, this paper finds that the higher the level of social adaptation is, the more obvious the promotion effect on the level of human (...) capital; for eastern cities, social adaptation can promote the improvement of the human capital level; for central or western cities, the relationship between social adaptation and human capital is not obvious and depends on the method selected for estimation. To enhance the social adaptability of individuals, the government leadership should actively create conditions, carry out targeted social adaptation training and active adaptation skills exchange for different social groups in order to strengthen social adaptability and enhance human capital. At the same time, policymakers need to consider the differences between the eastern, central and western regions and choose the most suitable human capital improvement action framework for the region to manage environmental uncertainty and make regional human capital sustainable competitive in the era of uncertainty. (shrink)

In an effort to fulfill the commands of Chairman Mao and Premier Zhou, our people are working strenuously to build our country into a powerful, modernized socialist state before the end of the century. Following the gradual progress of the four modernizations, the productive forces will rapidly grow, and the socialization level of production is bound to rise noticeably. How to understand the socialization of production, how to promptly readjust the relations of production and the superstructure in order to fit (...) in with the new situation in which the socialization level of production is continuously on the rise, and how to reform the management of industrial and agricultural enterprises as well as the administrative system of the national economy in order to quicken the speed of economic development pose a new problem calling for earnest study and exploration. (shrink)

bakhsh-i 1. Muqaddamah, Manṭiq, Umūr-i ʻāmmah, Ṭabīʻyāt, Ilāhīyāt.

베이컨은 타당한 철학 방법론으로 귀납법만을 인정한 경험론자로 평가받는다. 그런 평가는 귀납법이 학문의 정초를 위한 방법으로는 매우 불충분하다는 인식과 더불어 그의 철학 방법론이 근대철학의 형성에 공헌하지 못했다는 평가로 이어진다. 본 논문은 그의 귀납법에 대한 비판이 정당한가를 세밀히 검토해서, 그의 귀납법 내에 부재한다고 비판받는 점들이 오히려 그의 귀납법을 구성하는 핵심 특징임을 밝히려 한다. 그리고 지금까지 베이컨 철학 방법론의 현대적 의의를 드러내려 했던 연구자들조차 그의 귀납법 본질을 밝혀내지 못했는데, 그 주원인은 그들이 상호 모순되는 것처럼 보이는 그의 귀납법 특징들의 연관성 규명에 실패했기 때문이다. 본 (...) 논문은 그것을 밝혀줄 열쇠는 그의 우상론 재해석에 있음과 또한 다양한 그의 귀납법 특징들이 어떤 맥락에서 이해되어야만 하는가를 밝히려 한다. 마지막으로 그의 귀납법이 근대자연과학혁명에서 획기적 공헌을 했으며, 이미 지나간 과거의 철학사적 문제가 아니라, 모든 자연 탐구자들이 반드시 명심해야만 할 중요한 교훈을 주고 있음을 보여주려 한다. (shrink)

This series publishes outstanding monographs and edited volumes that investigate all aspects of Kant's philosophy, including its systematic relationship to other philosophical approaches, both past and present. Studies that appear in the series are distinguished by their innovative nature and ability to close lacunae in the research. In this way, the series is a venue for the latest findings in scholarship on Kant.