The current COVID-19 pandemic and the previous SARS/MERS outbreaks of 2003 and 2012 have resulted in a series of major global public health crises. We argue that in the interest of developing effective and safe vaccines and drugs and to better understand coronaviruses and associated disease mechenisms it is necessary to integrate the large and exponentially growing body of heterogeneous coronavirus data. Ontologies play an important role in standard-based knowledge and data representation, integration, sharing, and analysis. Accordingly, we initiated the (...) development of the community-based Coronavirus Infectious Disease Ontology in early 2020. -/- As an Open Biomedical Ontology (OBO) library ontology, CIDO is open source and interoperable with other existing OBO ontologies. CIDO is aligned with the Basic Formal Ontology and Viral Infectious Disease Ontology. CIDO has imported terms from over 30 OBO ontologies. For example, CIDO imports all SARS-CoV-2 protein terms from the Protein Ontology, COVID-19-related phenotype terms from the Human Phenotype Ontology, and over 100 COVID-19 terms for vaccines (both authorized and in clinical trial) from the Vaccine Ontology. CIDO systematically represents variants of SARS-CoV-2 viruses and over 300 amino acid substitutions therein, along with over 300 diagnostic kits and methods. CIDO also describes hundreds of host-coronavirus protein-protein interactions (PPIs) and the drugs that target proteins in these PPIs. CIDO has been used to model COVID-19 related phenomena in areas such as epidemiology. The scope of CIDO was evaluated by visual analysis supported by a summarization network method. CIDO has been used in various applications such as term standardization, inference, natural language processing (NLP) and clinical data integration. We have applied the amino acid variant knowledge present in CIDO to analyze differences between SARS-CoV-2 Delta and Omicron variants. CIDO's integrative host-coronavirus PPIs and drug-target knowledge has also been used to support drug repurposing for COVID-19 treatment. -/- CIDO represents entities and relations in the domain of coronavirus diseases with a special focus on COVID-19. It supports shared knowledge representation, data and metadata standardization and integration, and has been used in a range of applications. (shrink)

COVID-19 often manifests with different outcomes in different patients, highlighting the complexity of the host-pathogen interactions involved in manifestations of the disease at the molecular and cellular levels. In this paper, we propose a set of postulates and a framework for systematically understanding complex molecular host-pathogen interaction networks. Specifically, we first propose four host-pathogen interaction (HPI) postulates as the basis for understanding molecular and cellular host-pathogen interactions and their relations to disease outcomes. These four postulates cover the evolutionary dispositions involved (...) in HPIs, the dynamic nature of HPI outcomes, roles that HPI components may occupy leading to such outcomes, and HPI checkpoints that are critical for specific disease outcomes. Based on these postulates, an HPI Postulate and Ontology (HPIPO) framework is proposed to apply interoperable ontologies to systematically model and represent various granular details and knowledge within the scope of the HPI postulates, in a way that will support AI-ready data standardization, sharing, integration, and analysis. As a demonstration, the HPI postulates and the HPIPO framework were applied to study COVID-19 with the Coronavirus Infectious Disease Ontology (CIDO), leading to a novel approach to rational design of drug/vaccine cocktails aimed at interrupting processes occurring at critical host-coronavirus interaction checkpoints. Furthermore, the host-coronavirus protein-protein interactions (PPIs) relevant to COVID-19 were predicted and evaluated based on prior knowledge of curated PPIs and domain-domain interactions, and how such studies can be further explored with the HPI postulates and the HPIPO framework is discussed. (shrink)

v. 1. Qian Sugeladi zhe xue yan jiu, Sugeladi ji qi zhe xue si xiang -- v. 2. Si, shi, shi.

The constitutional provision for the separation of the Church and the State has been in existence for over 200 years. They are now referring to it, no longer remembering how it came about. The fact is that the French Revolution of 1789 was anti-feudal and anticlerical. It separated the affairs of the state from the ecclesiastical so that bishops and cardinals would govern the Church, not the state. The 1917 revolution in Russia also tore the triumvirate of "statehood, orthodoxy, nationality." (...) The state and the Church should have existed separately. The Bolsheviks rejected the old state and the Church, but in their legislation in 1919 the Decree recorded the separation of the Church from the state and the school from the Church. Because they disregarded law, morality and religion and absolutized the state, the state, and especially its punitive organs, trampled on morality, ethics, religion, clergy and their defenders... (shrink)

In the life of an individual as well as the whole of society, the worldview is one and the foundation of their spiritual life and its highest manifestation. Paraphrasing the well-known expression of Hegel's philosophy, It is possible to say with greater certainty that the worldview itself is a flower and a product, a factor and a consequence of the culture of the nation. In the historical past, the dominant worldview of mankind was a religious outlook; in other words - (...) in the spiritual world of humanity, religion was undivided. This pattern is quite relevant to our, Ukrainian, people. (shrink)

Collected works of Dge-lugs-pa scholar predominantly on doctrines, commentary on Vasubandhu's Abhidharmakośa, study on Abhisamayālaṅkāra of Pañcaviṃśatisāhasrikā Prajñāparāmitā, Buddhist logic, philosophy, rituals, etc.

Study on Am̥rtānubhava, philosophical classic by Jñānadeva, fl. 1290, Marathi religious leader.

Selected works of author's on critical analysis on different concepts of Buddhist doctrines and philosophy.

L'auteur veut mettre son ouvrage à la disposition de tous les penseurs africains et non pas seulement des philosophes. C'est en ces termes qu'il justifie la publication d'un texte par lequel il contribue à ce qu'ils sont de plus en plus nombreux à appeler «la problématique de la philosophie en Afrique». Et l'originalité, c'est précisément d'avoir opté pour la «phénoménologie» d'une question, au moment même où l'on pourrait croire soit qu'une réponse en a déjà été donnée, soit qu'il est plus (...) urgent d'y répondre. Mais ce que l'on croit perdre d'une main - la philosophie - on le récupère amplement de l'autre! Car, une fois le «questionneur» supposé de bonne foi, ou tout au moins de bonne volonté, le «questionné», lui, est un philosophe africain de formation européenne occidentale dont les attitudes possibles, face à la question posée, servent d'armature à toute la phénoménologie, et, à qui l'auteur suggère de consentir à n'être peut-être qu'un «penseur africain», mais de veiller à l'être pleinement. (shrink)

Lung nodules are an early symptom of lung cancer. The earlier they are found, the more beneficial it is for treatment. However, in practice, Chinese doctors are likely to cause misdiagnosis. Therefore, deep learning is introduced, an improved target detection network is used, and public datasets are used to diagnose and identify lung nodules. This paper selects the Mask-RCNN network and uses the dense block structure of Densenet and the channel shuffle convolution method to improve the Mask-RCNN network. The experimental (...) results prove that proposed algorithm is extremely effective. (shrink)

Commented article: HU, J. Embodiment and inspiration of Chinese philosophy of life in traditional music education. Trans/Form/Ação: revista de filosofia da Unesp, v. 47, n. 5, “Eastern thought 2”, e02400152, 2024. Available at: https://revistas.marilia.unesp.br/index.php/transformacao/article/view/15092.

We empirically examine the impact of corporate social responsibility (CSR) on CEO compensation using a large sample of the US firms from 1996 to 2010. We develop and test two hypotheses, the overinvestment hypothesis based on agency theory and the conflict–resolution hypothesis based on stakeholder theory. We find that the lag of CSR adversely affects both total compensation and cash compensation, after controlling for various firm and board characteristics. Our estimates show that an interquartile increase in CSR is followed by (...) a 4.35% (2.78%) decrease in total (cash) compensation. We also find an inverse association between lagged employee relations and CEO compensation. Our results are robust to the correction for endogeneity using instrumental variable approach. Taken together, our results support the conflict–resolution hypothesis, but not the CSR overinvestment argument. (shrink)

Noise will be inevitably mixed with music signals in the recording process. To improve the quality of music signals, it is necessary to reduce noise as much as possible. This article briefly introduces noise, the masking effect, and the spectral subtraction method for reducing noise in reverberant music. The spectral subtraction method was improved by the human ear masking effect to enhance its noise reduction performance. Simulation experiments were carried out on the traditional and improved spectral subtraction methods. The results (...) showed that the improved spectral subtraction method could reduce the noise in reverberant music more effectively; under an objective evaluation criterion, the signal-to-noise ratio, the de-reverberated music signal processed by the improved spectral subtraction method had a higher signal-to-noise ratio; under a subjective evaluation criterion, mean opinion score, the de-reverberated music signal processed by the improved spectral subtraction method also had a better evaluation. (shrink)

The way of our living and working has changed intensely throughout the past half-century. The era we live in is interlinked with rapid technological changes, paving the way for digitalization. The students are considered digital natives and are expected to have e-learning abilities to improve their academic effectiveness. However, digital readiness is an important factor that can play a valuable role in boosting students’ e-learning abilities and satisfaction. The previous studies of students’ e-learning abilities revealed the lack of students’ digital (...) readiness for academic achievements. Therefore, the present study aims to examine the role of digital readiness in the e-learning satisfaction of students. Based on the theory of motivation, the present study attempts to check the association of digital readiness with e-learning satisfaction. The current study also determines the relationship of digital readiness with entrepreneur psychological capital. Further, this study examines the correlation of entrepreneur psychological capital with e-learning satisfaction. The present study also assumes the mediating role entrepreneur of psychological capital and moderating role of mindfulness. For empirical analyses, this study gathered data from 376 music learning students of entrepreneur training institutes in China through a structured questionnaire method using a convenient sampling technique. This study applied partial least square structural equation modeling for empirical analyses using Smart PLS software. The present study confirmed that digital readiness positively correlates with e-learning satisfaction and psychological capital. The findings also acknowledged that psychological capital positively enhances e-learning satisfaction. The results also confirmed that psychological capital mediates the association between digital readiness and e-learning satisfaction. However, the outcomes revealed that mindfulness does not moderate the association between digital readiness and e-learning satisfaction. On the other hand, the findings acknowledged that mindfulness moderates the relationship between psychological capital and e-learning satisfaction. In addition, this study’s findings also serve the literature by providing important theoretical and practical implications. This study points out that digital readiness is an important antecedent to increasing students’ learning satisfaction and performance. The findings also suggest that students’ mindfulness could play a bridging role in enhancing their performance. (shrink)

Journal of Chinese Philosophy, EarlyView.

The formation control issue for a group of underactuated unmanned surface vehicles is discussed in the paper, and a staged finite-time control strategy for the USVs is proposed. Firstly, we try to steer each USV to its own starting point in the formation for a limited time, under the initial condition that each of these vehicles is parked at random. To deal with the nonholonomic behavior of the system, the dynamics of the USV is transformed into cascade systems. Then, the (...) finite-time controller is designed for each vehicle based on homogeneity theory. After each USV reaches its own starting point with desired orientation, the model of the vehicle is decomposed into two subsystems under the Serret-Frenet frame. In order to maintain the formation pattern, two finite-time distributed controllers are developed for the surge subsystem and the yaw subsystem, respectively. The settling time for the staged control strategy is limited. Numerical simulations are carried out to illustrate the effectiveness of the proposed formation control strategy. (shrink)

本书æ ̄国内第一部对公元前721-前221年的华夏体系500年进行理论总结的研究成æž."华夏主义"分析了华夏体系500年间影响大国兴衰的主要理论和思想,并从理论范式的角度总结出老子范式,孔子范式,商子范式 ,管子范式四大范式,它们分别在齐国,楚国,吴国,越国,魏国.

經濟倫理的對話 財富思想的對話 支配類型的對話 理念類型的對話 決策倫理的對話 《儒家與韋伯的五個對話》為跨越政治、經濟、宗教與方法學等領域的思想史學術創作。葉仁昌教授累積了將近三十年的思考與體會，很大膽並充滿創意地，對儒家與韋伯（Max Weber）開展了五個批判性的對話。包括了清教徒與東亞的經濟倫理、欠缺無限利潤心的儒家財富思想、道德型正當性的支配類型、義利之辨的四種理念類型，以及何不曰利的決策倫理省思。藉此，不只重構了韋伯若干論述 的框架，也爲儒家提供了新視角下的不同詮釋。 韋伯是一位經典的大師，葉仁昌教授卻不只具體地指出韋伯對儒家的理解盲點，還應用韋伯的方法學來新論儒家，更試圖補足韋伯對儒家在研究上的遺漏，完成韋伯未竟的探索，甚至重構韋伯有關支配類型的框架。當然，在這樣 的過程中，儒家也因為新的視角而得到了不同詮釋。.

Robert Talisse charges as doomed the Berlinian effort to infer liberal politics from value pluralism, based on the observation that it unavoidably vio- lates Hume’s law and that the two in fact clash in their basic logic. In arriving at this diagnosis, however, Talisse relies on several problematic assumptions about practical reasoning as well as about value pluralism and liberalism. As a result, he fails to appreciate the practical nature of practical reasoning and also fails to see the negative aspects (...) of value pluralism and of liberalism. Once these misconceptions get straightened out there is an increased opportunity for the Berlinian inference to succeed. (shrink)

本书是国家社会科学基金课题《唐末五代十国儒学研究》的研究成果，该课题以唐末五代十国时期的儒学为研究对象，把儒学范式的转变作为研究的中心问题，着重探讨了在唐宋社会变革的背景下，唐末五代十国时期儒学的范式 转变。本书通过考察唐末五代十国时期儒学核心概念、基本范畴的演进，寻绎出其在历史语境中“惟精惟微”的变化，提出如下观点：唐末五代十国儒学，是“唐宋变革”在学术形态上的重要表现，也是对这一时期社会巨变的思 想回应。唐末五代十国儒学是一种新范式的儒学，显示出由汉唐儒学向宋代儒学嬗变的过渡特点。.

The ancient Daoist document Hengxian 《恒先》 contains a fascinating and unique concept, Zuo 作 that expresses a unique view of the world and human affairs. There are three stages of Huo-Zuo 或作, Qi-Zuo 氣作, and Ren-Zuo 人作 to understand the meanings associated with Zuo. On a metaphysical level, Zuo implies the world’s actuation. Huo-Zuo explains how Hengxian 恒先 gave rise to material existence from Xuwu 虛無. During the process whereby Qi 氣 gave rise to all things, Qi was the inner (...) motivating force driving the evolution of the universe. Qi-Zuo is a specific manifestation of Huo-Zuo in the generation process. In the sphere of human affairs, divergence appears in the meanings of the concept of Zuo. By giving the standard of not interfering in the spontaneous Zuo of others, Hengxian 《恒先》 sets a criterion for Zuo in human affairs. (shrink)

因為現代醫藥之發達與進步，我們身體的痛已大多有了消解之道；但思想、心理與性靈的病卻是越來越讓我們感到憂傷，越來越教我們心生恐懼，也越來越侵犯到我們原本一心盼望單單純純地「活在此時此刻」這極其謙卑的權利 與心願。 顯然，現代科技仍然效力有限，而無端的生命苦難更是難以預期與估量。我們還是得時時回頭看看自己這一身，回頭想想自己這一生，並同時回頭思量自己這一顆心到底蘊藏著什麼寶貝，或許，這樣的自力救濟與自力更生纔是生 活的王道。 且讓我們一起來細細品味兩千多年前這一位東方的「生命療癒先行者」――莊子到底是怎麼看待他自己這一身、這一生、這一世以及時時刻刻跳動在「此時此刻」的這一顆心，而其中又有何特殊光景值得莊子大書特書，這也許是 人類千年不變的生命共業。 原本，我們一出生就無法自外於大自然，而「自然」原來就在我們完完整整的這一身，它的符碼（甚至是密碼）就藏在我們人人心底，就靠我們自己來記憶，來存取，來開啟我們與生俱來的自我療癒的能力，而莊子如是言，如是 行，如是思量，如是觀想，如是腳踏實地，如是心無旁鶩，如是存活於此時此刻──而他已然為我們落下這八個無比精采的篇章： ◆逍遙之遊──莊子一心渴望真自由，而他到底是如何滿足這心底深沉的渴望？又是如何從地面起身躍向那無邊無界的天空？ ◆齊物之論──莊子彷彿心無是非，口無虛言，而只是靜觀萬物，平等看待這世上的一切，他是如何能夠保有這份真真切切的「自知之明」？如何在夢醒之際清清楚楚地守著這僅有的清明之心？ ◆養生之主──莊子先是如同一般人，一心只盼望健健康康，無疾也無病，但他還深刻地警覺生命最大的痛──死亡隨時隨處在窺伺著我們，我們又能如何真正地跳出這幾乎無所不在的死亡的幽谷？ ◆人間之世──莊子深知世上難免無妄之災，更難防故意之敵，但我們還是得盡量避禍，盡力解厄，同時盡心地處理好所有與我們相連相繫的人際關係；不過，當不順心不如意之事迎面而來之際，我們又當如何舉重若輕地一肩承 擔？莊子顯然有他自己的法子。 ◆真人之身──莊子不是教主，也不想開宗立派，他只是始終關心本來無價無償的生命到底該怎麼被我們認真地看待，而那「無用之用」的奧妙又有誰能真正了解？ ◆渾沌之死──就莊子看來，「渾沌」本無生亦無死；而如果說我們總是自己在「找死」，並不是死亡找上我們，這雖然看似重話，卻可能有警醒人心的作用。原來，莊子的「生命之壺」暗藏玄機，而縱然生死之謎究竟無解，但 我們又何妨放下心來，自由自在地在這世上走上一回。 ◆自然之道──莊子當然不懂現代科技，但他已經知道運用機械的後遺症。設想時下所謂的「科技新貴」能夠放下「釣魚上鉤」的念頭，靜靜地佇立水岸，觀賞那魚兒水中游，大概就將別有一番生活情趣與生命體悟。 ◆幸福之夢──莊子應該和任何人一樣，都想幸幸福福過一生，但我們到底該怎麼尋找終生的伴侶（甚至是「絕配」）？日子又該怎麼過得舒適？而和自己又能如何做一輩子的至親好友？這些問題的解答，可能就是打開那幸福之 門的鑰匙吧！ 作者：葉海煙 輔仁大學哲學博士，美國哈佛大學訪問學人、東吳大學哲學系教授兼系主任、長榮大學哲學與宗教學系教授兼系主任、台灣哲學學會會長、錢穆故居執行長、台南市哲學學會會長。現任南神神學院神學研究所專任哲學教授、國立 成功大學兼任哲學教授。專長道家哲學，當代新儒學，當代倫理學比較研究，台灣文化研究。著有《莊子的生命哲學》、《老莊哲學新論》、《道德、理性與人文的向度》、《中國哲學的倫理觀》、《人文與哲學的對話》、《傳 統倫理的現代挑戰》、《莊子的處世智慧》、《老子診療室》、《臺灣學入門》、《道家倫理學：理論與實踐》、《哲學與人生》、《哲學在哪裡》等近二十種著作。.

This paper explores how to explain the applicability of classical mathematics to the physical world in a radically naturalistic and nominalistic philosophy of mathematics. The applicability claim is first formulated as an ordinary scientific assertion about natural regularity in a class of natural phenomena and then turned into a logical problem by some scientific simplification and abstraction. I argue that there are some genuine logical puzzles regarding applicability and no current philosophy of mathematics has resolved these puzzles. Then I introduce (...) a plan for resolving the logical puzzles of applicability. (shrink)

In this article, we examine the empirical association between firm value and CSR engagement for firms in sinful industries, such as tobacco, gambling, and alcohol, as well as industries involved with emerging environmental, social, or ethical issues, i.e., weapon, oil, cement, and biotech. We develop and test three hypotheses, the window-dressing hypothesis, the value-enhancement hypothesis, and the value-irrelevance hypothesis. Using an extesive US sample from 1995 to 2009, we find that CSR engagement of firms in controversial industries positively affects firm (...) value after controlling for various firm characteristics. To address the potential endogeneity problem, we further estimate a system of equations and change regression and continue to find a positive relation between CSR engagement and firm value. Our findings support the value-enhancement hypothesis and are consistent with the premise that the top management of US firms in controversial industries, in general, considers social responsibility important even though their products are harmful to human being, society, or environment. (shrink)

In Power and Moral Education in China, Wangbei Ye examines China’s recent initiation of school-based curriculum development in moral education as a means to analyze the power redistribution brought about by China’s economic reform. Though there is a great deal of scholarship dealing with moral education in China, the role of power has never been systematically discussed in relation to this topic.

本书包括:中西文化之“会通和合”;写在《中国审美意识的探讨》出版之际;学者的使命;“诗言志”小注等内容。.

Given the prevalence of employees’ workplace cheating behavior (WCB) and its cost to organizations, considerable scholarly effort has been invested in identifying both its antecedents and intrapersonal consequences. However, its interpersonal repercussions, particularly how and when WCB influences coworker relationships, remain underexplored. Our paper enriches the WCB literature by using social information processing theory to examine the effect of employee WCB on coworker disliking and subsequent coworker ostracism. Through a field survey study and experimental studies, we found that coworker disliking (...) mediates the positive relationship between WCB and coworker ostracism. Moreover, team ethical leadership strengthens the positive relationship between WCB and coworker disliking, and focal employees’ negative affectivity strengthens the positive relationship between coworker disliking and ostracism. Furthermore, team ethical leadership and focal employees’ negative affectivity strengthen the indirect effects of WCB on coworker ostracism via coworker disliking. Our findings have important theoretical and practical implications for the literature on WCB. (shrink)

The Value of Evidence thesis (VE) tells us to gather evidence before deciding in any decision problem, if the evidence is free. This appar- ently plausible principle faces two problems. First, it fails on evidence externalism or nonclassical decision theories. Second, it’s not general enough: it tells us to prefer gaining free evidence to gaining no evi- dence, but it doesn’t tell us to prefer gaining more informative evidence to gaining less informative evidence when both are free. This paper defends (...) an alternative value-of-evidence principle that solves the above two problems. We call it ‘the Comparative Value of Evidence for the Resolute (CVER).’ CVER not only generalizes VE to the comparative case but is also compatible with evidence externalism and nonclassical decision theories. Our argument, if successful, broadens the scope of the value-of-evidence principle and shows that it’s more robust than previously imagined. (shrink)

The debate between Uniqueness and Permissivism concerns whether a body of evidence sometimes allows multiple doxastic attitudes towards a proposition. An important motivation for Uniqueness is the so-called ‘arbitrariness argument,’ which says that Permissivism leads to some unacceptable arbitrariness with regard to one's beliefs. An influential response to the argument says that the arbitrariness in beliefs can be avoided by invoking epistemic standards. In this paper, I argue that such a response to the arbitrariness argument is unsuccessful. Then I defend (...) a new response: contrary to common conception, the arbitrariness resulted by Permissivism is acceptable. The basic idea is that the arbitrariness resulted by Permissivism is analogous to the arbitrariness in permissive actions and the latter arbitrariness is intuitively acceptable. I answer three possible objections against this analogy, which are all motivated by the thought that beliefs aim at the truth. In addressing the last objection, I draw inspiration from the recent debate on transformative experience. (shrink)

This article suggests that the historical figuration of Islam as well as the discourse of secularization has played a fundamental role in the constitution of Islam’s externality to Europe. The historical figuration of Islam as Europe’s enemy is haunting Europe. The European secularist anxiety today, which insists on the separation between the domains of the private and the public needs to be understood against the backdrop of this history. If Islam’s inability to separate the religious and the political was historically (...) the dominant motif through which Islam was registered as the arch-enemy, the post-secular, post-Enlightenment period registers Islam as an enemy through a cultural gesture. Derrida’s understanding of spectrality and the concept autoimmunity are deployed to suggest that Islam as a specter haunting Europe undermines the sovereign constitution of a self-identical Europe, but this haunting needs to be seen as Europe’s chance for a self-destructive conservation of Europe. European identity has to be rethought and renewed differently and this rethinking requires that we attend to the present as well as the past and future of Europe, which requires the opening of Europe to otherness and responsibility to the other. Such a rethinking of Europe’s history necessitates thinking about colonialism as well the living embodiments of this colonial legacy today, which are the immigrants. (shrink)