Results for 'Winona Barker'

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  1. TGF-Beta Signaling Proteins and the Protein Ontology.Arighi Cecilia, Liu Hongfang, Natale Darren, Barker Winona, Drabkin Harold, Blake Judith, Barry Smith & Wu Cathy - 2009 - BMC Bioinformatics 10 (Suppl 5):S3.
    The Protein Ontology (PRO) is designed as a formal and principled Open Biomedical Ontologies (OBO) Foundry ontology for proteins. The components of PRO extend from a classification of proteins on the basis of evolutionary relationships at the homeomorphic level to the representation of the multiple protein forms of a gene, including those resulting from alternative splicing, cleavage and/or posttranslational modifications. Focusing specifically on the TGF-beta signaling proteins, we describe the building, curation, usage and dissemination of PRO. PRO provides a framework (...)
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  2. The Protein Ontology: A Structured Representation of Protein Forms and Complexes.Darren Natale, Cecilia N. Arighi, Winona C. Barker, Judith A. Blake, Carol J. Bult, Michael Caudy, Harold J. Drabkin, Peter D’Eustachio, Alexei V. Evsikov, Hongzhan Huang, Jules Nchoutmboube, Natalia V. Roberts, Barry Smith, Jian Zhang & Cathy H. Wu - 2011 - Nucleic Acids Research 39 (1):D539-D545.
    The Protein Ontology (PRO) provides a formal, logically-based classification of specific protein classes including structured representations of protein isoforms, variants and modified forms. Initially focused on proteins found in human, mouse and Escherichia coli, PRO now includes representations of protein complexes. The PRO Consortium works in concert with the developers of other biomedical ontologies and protein knowledge bases to provide the ability to formally organize and integrate representations of precise protein forms so as to enhance accessibility to results of protein (...)
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  3. Framework for a Protein Ontology.Darren A. Natale, Cecilia N. Arighi, Winona Barker, Judith Blake, Ti-Cheng Chang, Zhangzhi Hu, Hongfang Liu, Barry Smith & Cathy H. Wu - 2007 - BMC Bioinformatics 8 (Suppl 9):S1.
    Biomedical ontologies are emerging as critical tools in genomic and proteomic research where complex data in disparate resources need to be integrated. A number of ontologies exist that describe the properties that can be attributed to proteins; for example, protein functions are described by Gene Ontology, while human diseases are described by Disease Ontology. There is, however, a gap in the current set of ontologies—one that describes the protein entities themselves and their relationships. We have designed a PRotein Ontology (PRO) (...)
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  4. The Report of the Public Discussion at Stockport, Between Mr. John Bowes ... And Mr. Joseph Barker ... The Question for Debate: - "Are the Scriptures of the Old and New Testaments of Supernatural Origin and Divine Authority ; Are the Doctrines Conducive to Morality and Virtue?". [REVIEW]John Bowes & Joseph Barker - 1855 - R. Bulman G. Gallie.
     
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  5. Well-Being, Disability, and Choosing Children.Matthew J. Barker & Robert A. Wilson - 2019 - Mind 128 (510):305-328.
    The view that it is better for life to be created free of disability is pervasive in both common sense and philosophy. We cast doubt on this view by focusing on an influential line of thinking that manifests it. That thinking begins with a widely-discussed principle, Procreative Beneficence, and draws conclusions about parental choice and disability. After reconstructing two versions of this argument, we critique the first by exploring the relationship between different understandings of well-being and disability, and the second (...)
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  6. Monism and Material Constitution.Stephen Barker & Mark Jago - 2014 - Pacific Philosophical Quarterly 95 (1):189-204.
    Are the sculpture and the mass of gold which permanently makes it up one object or two? In this article, we argue that the monist, who answers ‘one object’, cannot accommodate the asymmetry of material constitution. To say ‘the mass of gold materially constitutes the sculpture, whereas the sculpture does not materially constitute the mass of gold’, the monist must treat ‘materially constitutes’ as an Abelardian predicate, whose denotation is sensitive to the linguistic context in which it appears. We motivate (...)
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  7. Illocutionary Acts and Sentence Meaning.Stephen Barker - 2002 - Mind 111 (443):633-639.
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  8. Being Positive About Negative Facts.Mark Jago & Stephen Barker - 2012 - Philosophy and Phenomenological Research 85 (1):117-138.
    Negative facts get a bad press. One reason for this is that it is not clear what negative facts are. We provide a theory of negative facts on which they are no stranger than positive atomic facts. We show that none of the usual arguments hold water against this account. Negative facts exist in the usual sense of existence and conform to an acceptable Eleatic principle. Furthermore, there are good reasons to want them around, including their roles in causation, chance-making (...)
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  9. When Traditional Essentialism Fails: Biological Natural Kinds.Robert A. Wilson, Matthew J. Barker & Ingo Brigandt - 2007 - Philosophical Topics 35 (1-2):189-215.
    Essentialism is widely regarded as a mistaken view of biological kinds, such as species. After recounting why (sections 2-3), we provide a brief survey of the chief responses to the “death of essentialism” in the philosophy of biology (section 4). We then develop one of these responses, the claim that biological kinds are homeostatic property clusters (sections 5-6) illustrating this view with several novel examples (section 7). Although this view was first expressed 20 years ago, and has received recent discussion (...)
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  10.  25
    A New Model for the Origins of Chronic Disease.D. J. P. Barker - 2001 - Medicine, Health Care and Philosophy 4 (1):31-35.
    Living things are often plastic during their early development and are moulded by the environment. Many human fetuses have to adapt to a limited supply of nutrients, and in doing so they permanently change their physiology and metabolism. These programmed changes may be the origins of a number of diseases in later life, including coronary heart disease, stroke, diabetes and hypertension.
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  11.  4
    Intrinsically Alpha º Relations.E. Barker - 1988 - Annals of Pure and Applied Logic 39 (2):105.
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  12.  46
    E. Barker : Aristotle, Politics. Revised with an Introduction and Notes by R. F. Stalley. Pp. Xlvii+423; 2 Maps. Oxford: Oxford University Press, 1995. Paper, £6.99. [REVIEW]P. J. Rhodes - 1995 - The Classical Review 45 (2):461-461.
  13.  22
    Ernest Barker and the Classical Tradition: Two Studies.Robert B. Todd - 2006 - Polis 23 (2):368-384.
    This paper first traces the general influence of Ernest Barker's undergraduate training in Oxford's School of Literae Humaniores on his later work on ancient political thought, and in particular shows how Idealism conditioned his view that the major ancient texts were perennially relevant and also applicable to practical affairs. The second part of the paper is based on a letter that Barker wrote to E.R. Dodds in 1953 critical of Dodds's negative perspective in The Greeks and the Irrational (...)
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  14.  8
    Ernest Barker on the Composition and Structure of Aristotle's Politics.Eckart Schütrumpf - 2006 - Polis: The Journal for Ancient Greek Political Thought 23 (2):286-301.
    E. Barker twice wrote essays entitled ‘The composition and structure of Aristotle’s Politics’, first as a journal article in 1931, and later in 1946 as part of the introduction to his translation of the Politics. In these two essays, he came to exactly the opposite conclusions. In the first paper, he distinguished three periods in Aristotle’s life and assigned to each of them three ‘blocks’ in the Politics, based on the criterion of how closely these blocks were related to, (...)
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  15.  45
    Some Reflections on Two Books by Ellen Wood.Colin Barker - 1997 - Historical Materialism 1 (1):22-65.
    Some time ago, the editors of Monthly Review invited me to submit a short review of two recent books by Ellen Wood: The Pristine Culture of Capitalism, and Democracy Against Capitalism. I found myself, in the course of re-reading these books, filled with admiration for most of what the author said, and indeed, for the manner in which she presented her case. At various points, however, I found myself not fully satisfied. But a short review was not the place to (...)
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  16.  53
    Ethics and Ethos: The Buffering and Amplifying Effects of Ethical Behavior and Virtuousness. [REVIEW]Arran Caza, Brianna A. Barker & Kim S. Cameron - 2004 - Journal of Business Ethics 52 (2):169-178.
    Logical and moral arguments have been made for the organizational importance of ethos or virtuousness, in addition to ethics and responsibility. Research evidence is beginning to provide, empirical support for such normative claims. This paper considers the relationship between ethics and ethos in contemporary organizations by summarizing emerging findings that link virtuousness and performance. The effect of virtue in organizations derives from its buffering and amplifying effects, both of which are described.
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  17. BARKER, E. -The Politics of Aristotle. [REVIEW]R. Robinson - 1947 - Mind 56:398.
     
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  18. Joseph Barker and Popular Biblical Criticism in the Nineteenth Century.Timothy Larsen - 2000 - Bulletin of the John Rylands Library 82 (1):115-134.
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  19.  32
    Book Review Daniel Dennett. [REVIEW]Gillian Barker - 2005 - Philosophy of Science 72 (3):508-510.
  20.  34
    Respect for Persons, Informed Consent Andthe Assessment of Infectious Disease Risks in Xenotransplantation.Jeffrey H. Barker & Lauren Polcrack - 2001 - Medicine, Health Care and Philosophy 4 (1):53-70.
    Given the increasing need for solid organ and tissue transplants and the decreasing supply of suitable allographic organs and tissue to meet this need, it is understandable that the hope for successful xenotransplantation has resurfaced in recent years. The biomedical obstacles to xenotransplantation encountered in previous attempts could be mitigated or overcome by developments in immunosuppression and especially by genetic manipulation of organ source animals. In this essay we consider the history of xenotransplantation, discuss the biomedical obstacles to success, explore (...)
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  21. Continuity Through Revolutions: A Frame-Based Account of Conceptual Change During Scientific Revolutions.Xiang Chen & Peter Barker - 2000 - Philosophy of Science 67 (3):223.
    In this paper we examine the pattern of conceptual change during scientific revolutions by using methods from cognitive psychology. We show that the changes characteristic of scientific revolutions, especially taxonomic changes, can occur in a continuous manner. Using the frame model of concept representation to capture structural relations within concepts and the direct links between concept and taxonomy, we develop an account of conceptual change in science that more adequately reflects the current understanding that episodes like the Copernican revolution are (...)
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  22. Explaining Crossover and Superiority as Left-to-Right Evaluation.Chung-Chieh Shan & Chris Barker - 2005 - Linguistics and Philosophy 29 (1):91 - 134.
    We present a general theory of scope and binding in which both crossover and superiority violations are ruled out by one key assumption: that natural language expressions are normally evaluated (processed) from left to right. Our theory is an extension of Shan’s (2002) account of multiple-wh questions, combining continuations (Barker, 2002) and dynamic type-shifting. Like other continuation-based analyses, but unlike most other treatments of crossover or superiority, our analysis is directly compositional (in the sense of, e.g., Jacobson, 1999). In (...)
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  23.  10
    Ernest Barker and Greek Political Thought: Plato.Quentin Taylor - 2006 - Polis: The Journal for Ancient Greek Political Thought 23 (2):222-242.
    For much of the twentieth century Ernest Barker was the most frequently cited authority on Greek political thought in the English-speaking world. The centenary of his first publication, The Political Thought of Plato and Aristotle, provides a fitting occasion to commemorate his seminal and enduring contribution to the subject. In the first of two articles, I explore Barker’s treatment of Plato, particularly as a foil for developing his own synthetic brand of neo-idealism. With a focus on the Republic, (...)
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  24.  71
    The Biological Notion of Individual.Robert A. Wilson & Matthew J. Barker - 2013 - Stanford Encyclopedia of Philosophy.
    Individuals are a prominent part of the biological world. Although biologists and philosophers of biology draw freely on the concept of an individual in articulating both widely accepted and more controversial claims, there has been little explicit work devoted to the biological notion of an individual itself. How should we think about biological individuals? What are the roles that biological individuals play in processes such as natural selection (are genes and groups also units of selection?), speciation (are species individuals?), and (...)
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  25.  14
    Idealism and Theology: A Study of Presuppositions. Charles F. d'Arcy.H. Barker - 1900 - International Journal of Ethics 11 (1):132-134.
  26.  5
    The Ethical Theory of Hegel: A Study of the Philosophy of Right.H. Barker - 1923 - International Journal of Ethics 33 (2):216-218.
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  27.  2
    Alain Badiou a Critical Introduction.Jason Barker - 2002 - Pluto Press.
    A clear and concise introduction to the political philosophy of Alain Badiou, centred in a political context.
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  28.  25
    The Anatomy of Inquiry: Philosophical Studies in the Theory of Science.S. F. Barker - 1966 - Journal of Philosophy 63 (12):358-363.
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  29.  11
    Ernest Barker: Classics, England-Britain, and Europe, 1906–1960.Julia Stapleton - 2006 - Polis: The Journal for Ancient Greek Political Thought 23 (2):203-221.
    Ernest Barker’s contributions to the study of classical political thought have remained a benchmark in that field for much of the twentieth century. This introduction seeks to place his output in historical context, examining the professional, political and personal factors which underpinned his success as an interpreter of Plato and Aristotle, especially. It considers his education, the popular nature of his work, his ambiguous relationship to the establishment, his English-British patriotism, his European connections and perspective, his dual career as (...)
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  30.  44
    Barker and Achinstein on Goodman.Gary Sollazzo - 1972 - Philosophical Studies 23 (1-2):91 - 97.
    Barker and Achinstein think that it is not possible for a predicate like grue to serve as well as a predicate like green in the role of a qualitative or non-positional predicate. Their arguments consist in a number of attempts to show that one who possesses green in his language can do things with that predicate which one who must work with grue instead cannot do. However, they succeed in showing only that a qualitative predicate is better adapted to (...)
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  31. Barker, M-J., Gill, R., and Harvey, L. (2018). Mediated Intimacy: Sex Advice in Media Culture. Cambridge: Polity Press.Mediated Intimacy: Sex Advice in Media Culture. [REVIEW]Jamie Hakim - 2020 - Communications 45 (4):509-512.
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  32. The Pathway to Reality.H. Barker - 1905 - International Journal of Ethics 15 (2):256-258.
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  33. BARKER, S. F. - "Induction and Hypothesis: A Study of the Logic of Confirmation". [REVIEW]R. Harré - 1962 - Mind 71:412.
     
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  34.  13
    Peter Barker and Roger Ariew , Revolution and Continuity: Essays in the History and Philosophy of Early Modern Science. Washington, DC: The Catholic University of America Press, 1991. Pp. V + 222. ISBN 0-8132-0738-X. $42.95. [REVIEW]Antoni Malet - 1993 - British Journal for the History of Science 26 (1):88-89.
  35. Autism and the "Theory of Mind" Debate.Robert M. Gordon & John A. Barker - 1994 - In George Graham & G. Lynn Stephens (eds.), Philosophical Psychopathology. MIT Press.
  36.  50
    Dualisms, Discourse, and Development. [REVIEW]Drucilla K. Barker - 1998 - Hypatia 13 (3):83 - 94.
    This essay reviews a body of literature on feminism, development, and knowledge construction. This literature rejects essentialist constructions of women, challenges the universality of the Western scientific method, and creates a discursive space for reconstructing the dualisms embedded in the modern worldview. It suggests that an understanding of knowledge systems other than the modern one can aid us in constructing epistemologies that result in less dominating ways of producing knowledge.
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  37.  5
    Chris Barker, Educating Liberty: Democracy and Aristocracy in J. S. Mill's Political Thought (Rochester, N.Y.: University of Rochester Press, 2018). Pp. Viii, 267. $105.00. [REVIEW]D. N. Byrne - 2021 - Utilitas 33 (3):373-377.
  38.  11
    Monism and Material Constitution.Mark Jago Stephen Barker - 2014 - Pacific Philosophical Quarterly 95 (2):189-204.
    Are the sculpture and the mass of gold which permanently makes it up one object or two? In this article, we argue that the monist, who answers ‘one object’, cannot accommodate the asymmetry of material constitution. To say ‘the mass of gold materially constitutes the sculpture, whereas the sculpture does not materially constitute the mass of gold’, the monist must treat ‘materially constitutes’ as an Abelardian predicate, whose denotation is sensitive to the linguistic context in which it appears. We motivate (...)
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  39. Biological Individuals.Robert A. Wilson & Matthew J. Barker - 2019 - Stanford Encyclopedia of Philosophy 1 (1).
    The impressive variation amongst biological individuals generates many complexities in addressing the simple-sounding question what is a biological individual? A distinction between evolutionary and physiological individuals is useful in thinking about biological individuals, as is attention to the kinds of groups, such as superorganisms and species, that have sometimes been thought of as biological individuals. More fully understanding the conceptual space that biological individuals occupy also involves considering a range of other concepts, such as life, reproduction, and agency. There has (...)
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  40.  9
    A Complexity Theory Framework of Issue Movement.James R. Barker & Cedric E. Dawkins - 2020 - Business and Society 59 (6):1110-1150.
    This research draws on complexity theory to provide an alternative conceptualization of issue management. We use six dynamics of complexity drawn from complex adaptive systems—equipoise, turbulence, sensitive conditions, bifurcation, attractor emergence, and symmetry breaking—to develop a metaphorical framework that describes what occurs during various periods of issue activity and what propels issues from one period of activity to another. We illustrate the framework with a case study of the pharmaceutical industry response to the HIV/aids pandemic in Sub-Saharan Africa. The article (...)
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  41. Barker, Philip, Michel Foucault: Subversions of the Subject.W. McDonald - 1995 - Australasian Journal of Philosophy 73:631-631.
     
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  42.  12
    Common-Pool Resources and Population Genomics in Iceland, Estonia, and Tonga.Jeffrey H. Barker - 2003 - Medicine, Health Care and Philosophy 6 (2):133-144.
    This paper addresses the application of the ethical concept of trust and the legal and political concept of public trust to population genomics projects in Iceland, Estonia, and Tonga. Focusing on trust and public trust, the paper explores analogies between the genomics projects and the treatment of other common-pool resources, making use of the notion of trust as an ethical demand, derived from the works of Emmanuel Levinas and Knud Eljer Lgstrup. The paper discusses the degree to which the ethical (...)
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  43. Kuhn's Theory of Scientific Revolutions and Cognitive Psychology.Xiang Chen, Hanne Andersen & Peter Barker - 1998 - Philosophical Psychology 11 (1):5 – 28.
    In a previous article we have shown that Kuhn's theory of concepts is independently supported by recent research in cognitive psychology. In this paper we propose a cognitive re-reading of Kuhn's cyclical model of scientific revolutions: all of the important features of the model may now be seen as consequences of a more fundamental account of the nature of concepts and their dynamics. We begin by examining incommensurability, the central theme of Kuhn's theory of scientific revolutions, according to two different (...)
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  44.  22
    Working with the Metaphor of Life and Death.P. Barker - 2000 - Medical Humanities 26 (2):97-102.
    The experience of being human is intangible. As a result, descriptions of human experience rely heavily on metaphor to convey something of that whole lived experience. By contrast, contemporary scientific narratives of the mind emphasise the form of human thought and emotion, over the content of people's experience, where constructive attempts are made to explain the experience of self, through metaphorical allusion. This paper considers the importance of metaphor as a vehicle for expressing and exploring selfhood. Examples from the psychiatric (...)
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  45. Rescuing Dispositionalism From the Ultimate Problem: Reply to Barker and Smart.Matthew Tugby - 2012 - Analysis 72 (4):723-731.
    Barker and Smart have argued that dispositional monism is just as susceptible to the ultimate regress problem as Armstrong’s contingent necessitation view of laws. In this response, I consider what implications this conclusion has for the dispositional essentialist project more generally. I argue that it is the monistic aspect of dispositional monism, rather than the dispositional essentialist aspect, which is the source of the problem raised by Barker and Smart. I then outline a version of dispositional essentialism which (...)
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  46.  8
    Gillian Barker, Eric Desjardins, and Trevor Pearce Entangled Life: Organism and Environment in the Biological and Social Sciences: Dordrecht, Heidelberg, New York, London: Springer, 2014, Series: History, Philosophy and Theory of the Life Sciences, Vol. 4, 279 Pp, € 107,09.Antonine Nicoglou - 2015 - History and Philosophy of the Life Sciences 37 (2):222-224.
  47. The Cognitive Structure of Scientific Revolutions.Hanne Andersen, Peter Barker & Xiang Chen - 2006 - Cambridge University Press.
    Thomas Kuhn's Structure of Scientific Revolutions became the most widely read book about science in the twentieth century. His terms 'paradigm' and 'scientific revolution' entered everyday speech, but they remain controversial. In the second half of the twentieth century, the new field of cognitive science combined empirical psychology, computer science, and neuroscience. In this book, the theories of concepts developed by cognitive scientists are used to evaluate and extend Kuhn's most influential ideas. Based on case studies of the Copernican revolution, (...)
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  48.  89
    On the Ethics of Facial Transplantation Research.Osborne P. Wiggins, John H. Barker, Serge Martinez, Marieke Vossen, Claudio Maldonado, Federico V. Grossi, Cedric G. Francois, Michael Cunningham, Gustavo Perez-Abadia, Moshe Kon & Joseph C. Banis - 2004 - American Journal of Bioethics 4 (3):1 – 12.
    Transplantation continues to push the frontiers of medicine into domains that summon forth troublesome ethical questions. Looming on the frontier today is human facial transplantation. We develop criteria that, we maintain, must be satisfied in order to ethically undertake this as-yet-untried transplant procedure. We draw on the criteria advanced by Dr. Francis Moore in the late 1980s for introducing innovative procedures in transplant surgery. In addition to these we also insist that human face transplantation must meet all the ethical requirements (...)
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  49.  8
    Barker Ancient Greek Writers on Their Musical Past: Studies in Greek Musical Historiography. Pisa and Rome: Fabrizio Serra Editore, 2014. Pp. 114. €36. 9788862276894. [REVIEW]Tom Phillips - 2015 - Journal of Hellenic Studies 135:203-204.
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  50.  17
    Wench Tactics? Openings in Conditions of Closure.Ruth Fletcher, Diamond Ashiagbor, Nicola Barker, Katie Cruz, Nadine El-Enany, Nikki Godden-Rasul, Emily Grabham, Sarah Keenan, Ambreena Manji, Julie McCandless, Sheelagh McGuinness, Sara Ramshaw, Yvette Russell, Harriet Samuels, Ann Stewart & Dania Thomas - 2017 - Feminist Legal Studies 25 (1):1-23.
    Picking up the question of what FLaK might be, this editorial considers the relationship between openness and closure in feminist legal studies. How do we draw on feminist struggles for openness in common resources, from security to knowledge, as we inhabit a compromised space in commercial publishing? We think about this first in relation to the content of this issue: on image-based abuse continuums, asylum struggles, trials of protestors, customary justice, and not-so-timely reparations. Our thoughts take us through the different (...)
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