Chagas disease or American trypanosomiasis is an important health problem in Latin America. Due to the mobility of Latin American population around the world, countries without vector presence started to report disease cases. We developed a deterministic compartmental model in order to gain insights into the disease dynamics in a scenario without vector presence, considering congenital transmission and transmission by blood transfusion. The model was used to evaluate the epidemiological effect of control measures. It was applied to demographic data from (...) Spain and sensitivity analysis was performed on model parameters associated with control strategies. (shrink)

In the last few decades, the ethics of care as a feminist ethic has given rise to extensive literature, and has affected moral inquiries in many areas. It offers a distinctive challenge to the dominant moral theories: Kantian moral theory, utilitarianism, and virtue ethics. This chapter outlines the distinctive features and promising possibilities of the ethics of care, and the criticisms that have been made against it. It then examines the ethics of care’s recognition of human dependency and of the (...) importance of responding to needs; its interpretation of the roles of emotion and reason in moral understanding; and its critique of liberal individualism and development of a conception of the person as relational. The ethics of care contrasts care with justice, tries to integrate them, and reconceptualizes public and private life and morality. (shrink)

With the arrival of the nineteenth century, a process of change guided the treatment of three basic elements in the development of mathematics: rigour, the arithmetization and the clarification of the concept of function, categorised as the most important tool in the development of the mathematical analysis. In this paper we will show how several prominent mathematicians contributed greatly to the development of these basic elements that allowed the solid underpinning of mathematics and the consideration of mathematics as an axiomatic (...) way of thinking in which anyone can deduce valid conclusions from certain types of premises. This nineteenth century stage shares, possibly with the Heroic Age of Ancient Greece, the most revolutionary period in all history of mathematics. (shrink)

The ontogeny of the vertebrate retina has been a topic of interest to developmental biologists and human geneticists for many decades. Understanding the unfolding of the genetic program that transforms a field of progenitors cells into a functionally complex and multi‐layered sensory organ is a formidable challenge. Although classical genetic studies succeeded in identifying the key regulators of retina specification, understanding the architecture of their gene network and predicting their behavior are still a distant hope. The emergence of next‐generation sequencing (...) platforms revolutionized the field unlocking the access to genome‐wide datasets. Emerging techniques such as RNA‐seq, ChIP‐seq, ATAC‐seq, or single cell RNA‐seq are used to characterize eye developmental programs. These studies provide valuable information on the transcriptional and cis‐regulatory profiles of precursors and differentiated cells, outlining the trajectories that connect each intermediate state. Here, recent systems biology efforts are reviewed to understand the genetic programs shaping the vertebrate retina. (shrink)

This book examines the history of cosmopolitanism from its origins in the ancient world up to its use in Kantian political philosophy. Taking the idea of 'common property of the land' as a starting point, the author makes the original case that attention to this concept is needed to properly understand the notion of cosmopolitan citizenship. Offering a reconstruction of cosmopolitanism from an interdisciplinary point of view, Toward Kantian Cosmopolitanism shows how the concept sits at the intersection between philosophical debates, (...) legal realities and the origins of the construction of the discipline of international law. Essential reading for all researchers and advances students of cosmopolitanism, political philosophy and the history of international law, it broadens the current understanding of the concept of cosmopolitanism and reflects on cosmopolitan studies from a historical and philosophical point of view. (shrink)

The question around foreigners and their obligation to respect and fulfil the national - or civil - norms of the territory where they are; has become due the migration and multicultural movements once again a key one. Addressed by a multitude of authors along the centuries, the question has been answered based on the different placements around juridical and political concepts like citizenship, sovereignty, authority or law. In this investigation, the doctrinal development carried out around the obligatory nature of the (...) civil norm for foreigners in Spanish scholasticism is going to be considered. Specifically, due to its thoroughness and depth, the doctrine done by Francisco Suarez is going to be critically analysed. Once the answer given in our author's doctrine to the question posed has been established, we will consider the possible influences in the Anglo-Saxon sphere. (shrink)

Tradicionalmente la conceptualización del tópico persona se ha circunscrito a ámbitos como la teología, la filosofía o la antropología. Sin embargo, la incorporación del tópico a gran parte de los textos de naturaleza política, así como en las declaraciones de derechos y tratados internacionales adoptados a partir de la II Guerra Mundial ha supuesto la constitucionalización del mismo. Consecuentemente, como término constitucional su interpretación queda a merced de los actores jurídicos designados para ello en el sistema político constitucional. Es por (...) ello, que, con el fin de determinar el contenido de significado actual del tópico ha de atenderse a las sentencias que interpretan la norma fundante. En este artículo, centramos nuestro estudio en la jurisprudencia del Tribunal Constitucional Español. Esto nos permite poner de relieve el concepto de persona en ellas contenido: su alcance y sus limitaciones. (shrink)

Cosa significa credere? Qual è l’utilità della credenza? Per analizzare il contenuto delle credenze di un popolo possiamo prescindere dallo studio della cultura di quel popolo? I termini da noi adoperati hanno un contenuto semantico unico e unicamente determinato? Per rispondere a tali fondamentali interrogativi, l’Autrice analizza i concetti di credere e di credenza secondo il punto di vista dell’antropologo britannico Rodney Needham e l’attenzione viene rivolta principalmente al suo enorme debito intellettuale nei confronti del filosofo viennese Ludwig Wittgenstein.

In this book, the author examines the ethical implications of Artificial Intelligence systems as they integrate and replace traditional social structures in new sociocognitive-technological environments. She discusses issues related to the integrity of researchers, technologists, and manufacturers as they design, construct, use, and manage artificially intelligent systems; formalisms for reasoning about moral decisions as part of the behavior of artificial autonomous systems such as agents and robots; and design methodologies for social agents based on societal, moral, and legal values. Throughout (...) the book the author discusses related work, conscious of both classical, philosophical treatments of ethical issues and the implications in modern, algorithmic systems, and she combines regular references and footnotes with suggestions for further reading. This short overview is suitable for undergraduate students, in both technical and non-technical courses, and for interested and concerned researchers, practitioners, and citizens. (shrink)

Formas de representación de la violencia en El vuelo del tigre y Libro de navíos y borrascas de Daniel Moyano.

Elements of Moral Experience in Clinical Ethics Training and Practice: Sharing Stories with Strangers is a philosophical and professional memoir of the education, training, and professional development of becoming a clinical ethics consultant. Utilizing a phenomenological and narrative lens, this book offers a fresh and energizing window into the field of healthcare ethics by pairing compelling clinical narratives of what it is like to do clinical ethics consultation with clear reflections and accessible introductions to key philosophical, professional, and humanistic roots (...) for responsible practice. (shrink)

Lo siniestro, aunque es llamativo e interesante a nivel literario resulta difícil de investigar, sin embargo, se puede encontrar una forma de abordarlo en la noción de enunciado poético siniestro como unidad discursiva y como eje conceptual de lectura que se desplaza por el texto y da a conocer el fondo del mismo. Un medio para demostrarlo ha sido el estudio y análisis de la novela Cruz de olvido (1999) de Carlos Cortés. En este artículo, con base en los resultados (...) de esa investigación y en la reconsideración de otros elementos conceptuales, se expondrá como el enunciado poético siniestro aporta algunos elementos útiles para un acercamiento más concreto al ámbito de estudio conceptual de lo siniestro. En el mismo sentido se procurará hacer una aproximación a la manifestación de la infamia. (shrink)

In this study I intend to prove that there is a close connection between ethical purposes of Environmental Philosophy as World Philosophy and the idea of sacred nature as part of the “world” in a phenomenological sense, which includes sacred space as defined in the philosophy of religion. The main points that intersect here are: the idea of sacred space; the perception of virtue in a sacred world; the beauty of creation: nature, life, human sensibility. The theoretical background of this (...) study contains points of view that express phenomenological, hermeneutic, theological, and aesthetic conceptions belonging to authors and exegetes such as Mircea Eliade, William E. Paden, David Cave, Ion Ianoși, Douglas Allen, Arnold Berleant, and Vincent Blok. I believe that the neglect of the environment-as-a-condition-of-life (the consequences of which can already be seen in ecological imbalances) is caused by, among other factors, the desacralization of human attitudes towards nature and the world of life. Few people still have a feeling of sacred nature or the aesthetic emotion of perceiving beauty in natural forms. The relationship with the environment and nature is reduced to its exploitation as a source of economic profit or as a way for spending free time, a source of personal comfort devoid of any spiritual significance. Surely we cannot go back to archaic religions or medieval Christianity, but we can reintegrate into our moral values something of those cultures’ admiration and respect for the beauty/sublimity of nature and the world as expressions of divine creation, as something sacred. Philosophical debates related to this retrieval and their dissemination could be part of solving the ecological problems of the contemporary world. (shrink)

Should Lesbian and women's events have policies banning sadomasochists or sadomasochistic acts? This question is being heatedly debated in the Lesbian community. In this paper, I examine the moral and political problems with sadomasochism from a Lesbian-feminist perspective, concluding that sadomasochism is antifeminist and antiliberatory for many reasons. Then, given this conclusion, I explore how events such as women's music festivals should determine their policies about sadomasochism.

The main argument of the article regards Aristotle’s anti-realistic account, which presents a different viewpoint from that which simply fulfils or negates the truth-values of our statements on Mixed Constitutions. In modern times, the idea of a Constitution of many minds or of many individuals is proposed by Sunstein and by Hart, who maintain that neither intentions in juridical procedure nor Constitutional provisions can produce an ideal Constitution. Thus any interpretative procedure assigning to legal reality any definite, once-and-for-all meaning is (...) precarious, according to Aristotle who asks whether we can gain epistemic access to the real essences of Constitutions and their structure. These ideas respond to a challenge in the Works of Contiades, who will help us to turn the ideal Constitution into a realisable model in the situation in which we live nowadays. This is the main challenge to be met by the institutions of Europe in order to safeguard the nature of historical and intellectual values. (shrink)

Optando por la retórica, Las Casas busca un modelo antropológico nuevo, distinto tanto del humanismo elitista, como del erasmismo voluntarista. En esta búsqueda quisiéramos poner énfasis, argumentando a favor de un resultado revolucionario a la luz de sus objetivos prácticos: cesar el homicidio y garantizar la libertad a los indios en cada aspecto de su vida. Desde aquí, nos referiremos a esta postura revolucionaria que bebe de Aristóteles y de santo Tomás, pero que es capaz de superarlos, a favor de (...) una defensa de lo propiamente humano, que estriba precisamente en reconocer que todas las comunidades tienen la posibilidad de realizarse autónomamente. Por esto, creemos que se puede hallar, en Bartolomé de las Casas, una importante contribución a la cuestión del reconocimiento, pero aún más, un importante punto de partida para los desafíos de una filosofía intercultural. (shrink)

En 1919, la même année où Jean Giraudoux fait son « Adieu à la guerre », il écrit « Les morts d’Elpénor ». En 1926, à côté de trois autres histoires, ce texte intégrera le corps d’Elpénor, déterminant l’ensemble, une collection de quatre textes écrits pendant dix-huit ans, le premier étant « Cyclope », écrit en 1908 ; le deuxième, « Sirènes », en 1912 ; le troisième en 1919 ; et le dernier en 1926, « Les nouvelles morts d’Elpénor (...) ». Quand « Cyclope » et « Sirènes » sortent respectivement chez Le Matin en 1908 et chez Paris-Journal en 1912 aucun d’entre eux ne mentionne Elpénor. Bref, c’est avec le développement des deux dernières histoires, que Elpénor, cette figure effacée chez Homère et absente dans les deux premiers textes de Giraudoux, vole la vedette. Cet article voudrait montrer comment la mise à jour du héros et de ses histoires est en dialogue avec la guerre vécue par l’auteur, pour proposer comment les vieilles histoires, lorsqu’elles sont renouvelées, participent à un processus qui leur permet d’élaborer les défis du présent, communiquant le présent, à travers un code déjà public, l’Odyssée. (shrink)

The figure of chiasmus, which plays a key role inside Merleau-Ponty’s thought, makes it possible to address the way Castoriadis defines the imaginary throughout his entire work from a new perspective, as well as to shed light on some complexities concerning the relation between instituted and instituting. Tthis article emphasizes the intertwining of three pair of concepts, each of which corresponds to a different but yet interrelated aspect of his philosophy: psyche-society, tradition-innovation, and autonomy-heteronomy.

Este artigo aborda a temática ética na obra Suma Teológica de Tomás de Aquino. Mais precisamente visamos demonstrar a maneira em que se dá o tratamento da moralidade no âmbito social, no interior das comunidades. Tenho a intenção neste trabalho de ajudar a explicitar o caráter comunitário da ética de Tomás de Aquino, e mais precisamente, estou interessada em delimitar criticamente os elementos constitutivos da formulação filosófica por Tomás de Aquino do conceito de comunidade moral na Suma Teológica.

The importance of mathematics in the context of the scientific and technological development of humanity is determined by the possibility of creating mathematical models of the objects studied under the different branches of Science and Technology. The arithmetisation process that took place during the nineteenth century consisted of the quest to discover a new mathematical reality in which the validity of logic would stand as something essential and central. Nevertheless, in contrast to this process, the development of mathematical analysis within (...) a framework that largely involves intuition and geometry is a fact that cannot go unnoticed amongst the mathematics community, as we shall show in this paper through the research made by Bernhard Riemann on complex variables. (shrink)

Este artículo analiza lo que nos cuentan las imágenes fotográficas en su reverso y en las huellas del verso, a través de las anotaciones, marcas o descripciones que contienen, que entregan información importante de su contexto de producción, de los sujetos u objetos fotografiados y de su trayectoria. Así, se configura un sentido apropiado de la imagen. Este artículo, pone el foco en imágenes fotográficas escolares porque representan un espacio de convivencia particular y de intercambio de experiencias que, en alguna (...) medida, se captura y resguarda en ellas. En los pliegues, en los bordes oscurecidos o desgastados, en los márgenes marchitos y en las marcas de óxido o de otros materiales, es posible también encontrar historias, restos de memorias, afectos y rostros en un contrapunto que va más allá de la motivación del fotógrafo para captar el instante en un encuadre específico. Para el análisis, se presentan algunas imágenes fotográficas pertenecientes al archivo escolar de un centro educativo de la ciudad de Talca en la región del Maule (Chile), pues permiten develar el significado familiar, mnemónico y comunitario que estas adquieren al reunirse en ese repertorio. Este valor igualmente se desprende de la observación del material oculto en el reverso y de las marcas del verso de las imágenes fotográficas. (shrink)

Type 2 diabetes has been considered a public health threat due to its growing prevalence, particularly in the older population. It is important to know the effects of psychosocial stress and its potential consequences for some basic cognitive processes that are important in daily life. Currently, there is very little information about how people with T2D face acute psychosocial stressors, and even less about how their response affects working memory, which is essential for their functionality and independence. Our aim was (...) to characterize the response to an acute laboratory psychosocial stressor and its effects on WM in older people with T2D. Fifty participants with T2D from 52 to 77 years old were randomly assigned to a stress or control condition. Mood and physiological responses to tasks were measured. In addition, participants completed a WM test before and after the stress or control task. Our results showed that the TSST elicited higher negative affect and greater C and sAA responses than the control task. No significant differences in WM were observed depending on the exposure to stress or the control task. Finally, participants who showed higher C and sAA responses to the stressor had lower WM performance. Our results indicate that medically treated older adults with T2D show clear, typical mood and physiological responses to an acute psychosocial stressor. Finally, the lack of acute psychosocial stress effects on WM suggests that it could be related to aging and not to this disease, at least when T2D is adequately treated. (shrink)

Exposición realizada por la Doctora en Filosofía Contemporánea Lorena Souyris Oportot, en el ciclo de conversaciones “Crítica a la Epidemiología Política. Prácticas y racionalidad neoliberales en tiempos de pandemia”, organizado por el equipo editorial de la Revista de Filosofía Otrosiglo, octubre – diciembre 2020. Disponible en Youtube, canal Revista Otrosiglo. Lecture by Lorena Souyris Oportot, Ph. D., in the cycle of conversations “Criticism to the Political Epidemiology. Neoliberal practices and rationality in times of pandemics”, event organized by the (...) editorial team of the Philosophy Magazine Otrosiglo, october – december 2020. Available on Youtbe, channel Revista Otrosiglo. (shrink)

Over the last decade, our appreciation of the importance of the nucleolus for cellular function has progressed from the ordinary to the extraordinary. We no longer think of the nucleolus as simply the site of ribosome production, or a dynamic subnuclear body noted by pathologists for its changes in size and shape with malignancy. Instead, the nucleolus has emerged as a key controller of many cellular processes that are fundamental to normal cell homeostasis and the target for dysregulation in many (...) human diseases; in some cases, independent of its functions in ribosome biogenesis. These extra‐nucleolar or new functions, which we term “non‐canonical” to distinguish them from the more traditional role of the nucleolus in ribosome synthesis, are the focus of this review. In particular, we explore how these non‐canonical functions may provide novel insights into human disease and in some cases new targets for therapeutic development. (shrink)

El propósito de este artículo es exponer la interpretación de la ideología en la obra_ Trabajo manual y trabajo intelectual. Una crítica de la epistemología_ de Alfred Sohn-Rethel entendida como inconsciente del sujeto transcendental, la cual pivota en torno al famoso término _abstracción real_ [_Realabstraktion_] como principio de síntesis social; y, por otro lado, medir someramente sus _alcances _y_ limitaciones _respecto de las nuevas lecturas de Marx, concretamente, de la crítica de la escisión del valor [_Wertabspaltungskritik_].

This paper aims to apply drama tasks (Gerard Finger, 2000) in the English class- room, which will add dynamism to the classroom, for the development of students’ oral competences. The aim is to work with drama in the Primary Education class- room through a series of tasks to improve oral communication, teamwork skills and to foster students’ self-esteem and confidence when producing oral language. This project addresses pupils in the sixth level of Primary Education. Theatre is a very versatile tool (...) that provides many resources and learning, helping to improve aspects such as corporal and oral expression and cooperative work. (shrink)

Desde mediados del siglo XX, el devenir de la salvaguarda relacionada con las viviendas ha avanzado desde la monumentalidad hasta el contexto, desde la individualización hasta la caracterización paisajística, desde las condiciones materiales hasta los aspectos vivenciales. Sin embargo, amparar el cuerpo de las residencias típicas de cada territorio, en especial en los dinámicos marcos urbanos, resultó —y resulta— un desafío. Las experimentaciones de propuestas hacia un amparo residencial a más largo plazo han coincidido en dos aspectos de interés: la (...) promoción de indicadores de sustentabilidad patrimonial, inscriptos en cada marco estatal-local preservacionista, junto con el reconocimiento y el tratamiento del rol usuario. En este sentido, desde variables histórico-arquitectónicas y sociales se propuso la construcción y la aplicación de indicadores de sustentabilidad patrimonial residencial para visibilizar problemas y potencialidades hacia una formulación de estrategias de preservación apropiadas. Para ello se abordó la ciudad de Mar del Plata, una aglomeración intermedia bonaerense paradigmática debido a sus dinamismos pasados y presentes, con foco en sus chalets “estilo Mar del Plata” y sus usuarios. Se analizaron dos barrios históricos —Stella Maris y La Perla—, donde sobrevive una relevante diversidad de chalets en un marco de múltiples riesgos que afectan su permanencia. Desde una perspectiva principalmente cualitativa, apoyada por datos cuantitativos, se articularon relevamientos in situ, fuentes escritas (investigaciones previas, artículos científicos, cartas patrimoniales), gráficas (planimetrías, fotografías, imágenes aéreas) y orales (encuestas, entrevistas). De esta manera, la indagación desarrollada permitió avanzar en renovados caminos para progresar en la salvaguarda del legado residencial contextual. (shrink)