The somatic mutation theory (SMT) of cancer has been and remains the prevalent theory attempting to explain how neoplasms arise and progress. This theory proposes that cancer is a clonal, cell‐based disease, and implicitly assumes that quiescence is the default state of cells in multicellular organisms. The SMT has not been rigorously tested, and several lines of evidence raise questions that are not addressed by this theory. Herein, we propose experimental strategies that may validate the SMT. (...) We also call attention to an alternative theory of carcinogenesis, the tissue organization field theory (TOFT), which posits that cancer is a tissue‐based disease and that proliferation is the default state of all cells. Based on epistemological and experimental evidence, we argue that the TOFT compellingly explains carcinogenesis, while placing it within an evolutionarily relevant context.magnified imagemagnified imageAna Soto and Carlos Sonnenschein are at Tufts University School of Medicine, Boston, MA, USA. (shrink)

Most of these eight essays on contemporary figures were given as lectures or speeches between 1990 and 1996. A piece on Ernst Cassirer’s humanistic legacy gives the collection its title, but the other subjects treated are far-ranging: Karl Jaspers on the clash of religious cultures, Georg Henrik von Wright’s noncognitive ethics, Gershom Scholem’s magisterial biography of the kabbalist Sabbatai Sevi, Karl-Otto Apel’s hermeneutics, Johann Baptist Metz on the Jewish element in Christianity, Michael Theunissen on the relation of negative theology to (...) social theory, and a review of the work of script writer and film director Alexander Kluge. Habermas unifies this panoply by his fascination with the transformation of the modern West’s key symbols through their confrontation with other cultures. Prime among these symbols are language and religious doctrines, especially Christian and Jewish. When he examines this general theme in particular cases, Habermas first presents an exposé of a thinker, then raises critical questions, and finally points out insights of enduring significance. One decided advantage of his method is its attention to clarity and organization. Probably because these essays were originally delivered orally, they never leave the reader in doubt as to what topics they will handle and when each is being taken up. (shrink)

Cancer research is experiencing ‘paradigm instability’, since there are two rival theories of carcinogenesis which confront themselves, namely the somatic mutation theory and the tissue organization field theory. Despite this theoretical uncertainty, a huge quantity of data is available thanks to the improvement of genome sequencing techniques. Some authors think that the development of new statistical tools will be able to overcome the lack of a shared theoretical perspective on cancer by amalgamating as many data (...) as possible. We think instead that a deeper understanding of cancer can be achieved by means of more theoretical work, rather than by merely accumulating more data. To support our thesis, we introduce the analytic view of theory development, which rests on the concept of plausibility, and make clear in what sense plausibility and probability are distinct concepts. Then, the concept of plausibility is used to point out the ineliminable role played by the epistemic subject in the development of statistical tools and in the process of theory assessment. We then move to address a central issue in cancer research, namely the relevance of computational tools developed by bioinformaticists to detect driver mutations in the debate between the two main rival theories of carcinogenesis. Finally, we briefly extend our considerations on the role that plausibility plays in evidence amalgamation from cancer research to the more general issue of the divergences between frequentists and Bayesians in the philosophy of medicine and statistics. We argue that taking into account plausibility-based considerations can lead to clarify some epistemological shortcomings that afflict both these perspectives. (shrink)

The somatic mutation theory has been the prevailing paradigm in cancer research for the last 50 years. Its premises are: (1) cancer is derived from a single somatic cell that has accumulated multiple DNA mutations, (2) the default state of cell proliferation in metazoa is quiescence, and (3) cancer is a disease of cell proliferation caused by mutations in genes that control proliferation and the cell cycle. From this compelling simplicity, an increasingly complicated picture has emerged as more than (...) 100 oncogenes and 30 tumor suppressor genes have been identified. To accommodate this complexity, additional ad hoc explanations have been postulated. After a critical review of the data gathered from this perspective, an alternative research program has been proposed. It is based on the tissue organization field theory, the premises of which are that carcinogenesis represents a problem of tissue organization, comparable to organogenesis, and that proliferation is the default state of all cells. The merits of these competing theories are evaluated herein. BioEssays 26:1097–1107, 2004. © 2004 Wiley Periodicals, Inc. (shrink)

The building of a global model of carcinogenesis is one of modern biology’s greatest challenges. The traditional somatic mutation theory is now supplemented by a new approach, called the Tissue Organization Field Theory. According to TOFT, the original source of cancer is loss of tissue organization rather than genetic mutations. In this paper, we study the argumentative strategy used by the advocates of TOFT to impose their view. In particular, we criticize their claim (...) of incompatibility used to justify the necessity to definitively reject SMT. First, we note that since it is difficult to build a non-ambiguous experimental demonstration of the superiority of TOFT, its partisans add epistemological and metaphysical arguments to the debate. This argumentative strategy allows them to defend the necessity of a paradigm shift, with TOFT superseding SMT. To do so, they introduce a notion of incompatibility, which they actually use as the Kuhnian notion of incommensurability. To justify this so-called incompatibility between the two theories of cancer, they move the debate to a metaphysical ground by assimilating the controversy to a fundamental opposition between reductionism and organicism. We show here that this argumentative strategy is specious, because it does not demonstrate clearly that TOFT is an organicist theory. Since it shares with SMT its vocabulary, its ontology and its methodology, it appears that a claim of incompatibility based on this metaphysical plan is not fully justified in the present state of the debate. We conclude that it is more cogent to argue that the two theories are compatible, both biologically and metaphysically. We propose to consider that TOFT and SMT describe two distinct and compatible causal pathways to carcinogenesis. This view is coherent with the existence of integrative approaches, and suggests that they have a higher epistemic value than the two theories taken separately. (shrink)

The building of a global model of carcinogenesis is one of modern biology’s greatest challenges. The traditional somatic mutation theory is now supplemented by a new approach, called the Tissue Organization Field Theory. According to TOFT, the original source of cancer is loss of tissue organization rather than genetic mutations. In this paper, we study the argumentative strategy used by the advocates of TOFT to impose their view. In particular, we criticize their claim (...) of incompatibility used to justify the necessity to definitively reject SMT. First, we note that since it is difficult to build a non-ambiguous experimental demonstration of the superiority of TOFT, its partisans add epistemological and metaphysical arguments to the debate. This argumentative strategy allows them to defend the necessity of a paradigm shift, with TOFT superseding SMT. To do so, they introduce a notion of incompatibility, which they actually use as the Kuhnian notion of incommensurability. To justify this so-called incompatibility between the two theories of cancer, they move the debate to a metaphysical ground by assimilating the controversy to a fundamental opposition between reductionism and organicism. We show here that this argumentative strategy is specious, because it does not demonstrate clearly that TOFT is an organicist theory. Since it shares with SMT its vocabulary, its ontology and its methodology, it appears that a claim of incompatibility based on this metaphysical plan is not fully justified in the present state of the debate. We conclude that it is more cogent to argue that the two theories are compatible, both biologically and metaphysically. We propose to consider that TOFT and SMT describe two distinct and compatible causal pathways to carcinogenesis. This view is coherent with the existence of integrative approaches, and suggests that they have a higher epistemic value than the two theories taken separately. (shrink)

Since the 1970s, the origin of cancer is being explored from the point of view of the Somatic Mutation Theory (SMT), focusing on genetic mutations and clonal expansion of somatic cells. As cancer research expanded in several directions, the dominant focus on cells remained steady, but the classes of genes and the kinds of extra-genetic factors that were shown to have causal relevance in the onset of cancer multiplied. The wild heterogeneity of cancer-related mutations and phenotypes, along with the (...) increasing complication of models, led to an oscillation between the hectic search of 'the' few key factors that cause cancer and the discouragement in face of a seeming 'endless complexity'. To tame this complexity, cancer research started to avail itself of the tools that were being developed by Systems Biology. At the same time, anti-reductionist voices began claiming that cancer research was stuck in a sterile research paradigm. This alternative discourse even gave birth to an alternative theory: the Tissue Organization Field Theory (TOFT). A deeper philosophical analysis shows the serious limits of both reductionist and anti-reductionist positions and of their polarization. This book demonstrates that a radical philosophical reflection is necessary to drive cancer research out of its impasses. At the very least, this will be a reflection on the assumptions of different kinds of cancer research, on the implications of what cancer research has been discovering over 40 years and more, on a view of scientific practice that is most able to make sense of the cognitive and social conflicts that are seen in the scientific community (and in its results), and, finally, on the nature of living entities with which we entertain this fascinating epistemological dance that we call scientific research. The proposed Dynamic and Relational View of carcinogenesis is a starting point in all these directions. (shrink)

The Somatic Mutation Theory has been challenged on its fundamentals by the Tissue Organization Field Theory of Carcinogenesis. However, a recent publication has questioned whether TOFT could be a valid alternative theory of carcinogenesis to that presented by SMT. Herein we critically review arguments supporting the irreducible opposition between the two theoretical approaches by highlighting differences regarding the philosophical, methodological and experimental approaches on which they respectively rely. We conclude that SMT has not explained (...) carcinogenesis due to severe epistemological and empirical shortcomings, while TOFT is gaining momentum. The main issue is actually to submit SMT to rigorous testing. This concern includes the imperatives to seek evidence for disproving one’s hypothesis, and to consider the whole, and not just selective evidence. (shrink)

We synthesize literature from organization theory and political sociology to develop a conceptual lens from which organizing can be examined as a process whereby institutional structures are changed in ways similar to how social movements change entire societies. Implied is that hegemonic power structures maintain existing institutional structures by either resisting insurgencies or by making them seem senseless in the first place.

In this paper, we set out to develop a theoretical and conceptual framework for the new field of Radical Embodied Cognitive Neuroscience. This framework should be able to integrate insights from several relevant disciplines: theory on embodied cognition, ecological psychology, phenomenology, dynamical systems theory, and neurodynamics. We suggest that the main task of Radical Embodied Cognitive Neuroscience is to investigate the phenomenon of skilled intentionality from the perspective of the self-organization of the brain-body-environment system, while doing (...) justice to the phenomenology of skilled action. In previous work, we have characterized skilled intentionality as the organism's tendency toward an optimal grip on multiple relevant affordances simultaneously. Affordances are possibilities for action provided by the environment. In the first part of this paper, we introduce the notion of skilled intentionality and the phenomenon of responsiveness to a field of relevant affordances. Second, we use Friston's work on neurodynamics, but embed a very minimal version of his Free Energy Principle in the ecological niche of the animal. Thus amended, this principle is helpful for understanding the embeddedness of neurodynamics within the dynamics of the system “brain-body-landscape of affordances.” Next, we show how we can use this adjusted principle to understand the neurodynamics of selective openness to the environment: interacting action-readiness patterns at multiple timescales contribute to the organism's selective openness to relevant affordances. In the final part of the paper, we emphasize the important role of metastable dynamics in both the brain and the brain-body-environment system for adequate affordance-responsiveness. We exemplify our integrative approach by presenting research on the impact of Deep Brain Stimulation on affordance responsiveness of OCD patients. (shrink)

Is logic normative for belief? A standard approach to answering this question has been to investigate bridge principles relating claims of logical consequence to norms for belief. Although the question is naturally an epistemic one, bridge principles have typically been investigated in isolation from epistemic debates over the correct norms for belief. In this paper we tackle the question of whether logic is normative for belief by proposing a Kripkean model theory accounting for the interaction between logical, doxastic, epistemic (...) and deontic notions and using this model theory to show which bridge principles are implied by epistemic norms that we have independent reason to accept, for example, the knowledge norm and the truth norm. We propose a preliminary theory of the interaction between logical, doxastic, epistemic and deontic notions that has among its commitments bridge principles expressing how logic is normative for belief. We also show how our framework suggests that logic is exceptionally normative. (shrink)

Is logic normative for belief? A standard approach to answering this question has been to investigate bridge principles relating claims of logical consequence to norms for belief. Although the question is naturally an epistemic one, bridge principles have typically been investigated in isolation from epistemic debates over the correct norms for belief. In this paper we tackle the question of whether logic is normative for belief by proposing a Kripkean model theory accounting for the interaction between logical, doxastic, epistemic (...) and deontic notions and using this model theory to show which bridge principles are implied by epistemic norms that we have independent reason to accept, for example, theknowledge normand thetruth norm. We propose a preliminary theory of the interaction between logical, doxastic, epistemic and deontic notions that has among its commitments bridge principles expressing how logic is normative for belief. We also show how our framework suggests that logic is exceptionally normative. (shrink)

According to the BSM- Supergravitation Unified Theory (BSM-SG), the energy is indispensable feature of matter, while the matter possesses hierarchical levels of organization from a simple to complex forms, with appearance of fields at some levels. Therefore, the energy also follows these levels. At the fundamental level, where the primary energy source exists, the matter is in its primordial form, where two super-dense fundamental particles (FP) exist in a classical pure empty space (not a physical vacuum). They are (...) associated with the Planck scale parameters of frequency and distance and interact by Supergravitational forces. These forces are inverse proportional to the cube of distance at pure empty space and they are based on frequency interactions. Since the two FPs have different intrinsic frequencies, the SG forces appear different for interactions between the like and unlike FPs and may change the sign. This primordial form of matter exists in the super-heavy black holes located in the center of each well formed galaxy. The next upper level of matter organization includes the underlying structure of the physical vacuum, called a Cosmic Lattice, and the structure of elementary particles. They have common substructure elements obtained by specific crystallization process preceding the formation of the observable galaxies. The Cosmic Lattice, forming a space known as a physical vacuum, is responsible for the existence and propagation of the physical fields: electrical, magnetic, Newtonian gravity and inertia. The energy of physical vacuum is in two forms: Static (enormous) and Dynamic (weak). The Static energy is directly related to the Newtonian mass by the Einstein equation E = mc^2 and it is a primary source of the nuclear energy. The Dynamic energy is responsible for the existence of the electric and magnetic fields, the constant speed of light and the quantum mechanical properties of the physical vacuum. The next upper energy level is the dynamical energy of excited atoms and molecules. At this level a hidden energy wells exit, such as the internal energy of the electron and the internal energy of atoms with more than one electron. The next upper energy level is at some organic molecules and particularly in the biomolecules that contain ring atomic structures. In such a structure, some quantum states are not emitted immediately, but rotating in the ring. While in organic molecules the energy stored in such a ring is released by a chemical process, in the long chain molecule of proteins in the living organism the stored energy can be released simultaneously by triggering. A huge number of atomic rings are contained in the DNA strands. The release of the energy stored in DNA, for example, is an avalanche process that causes an emission of entangled photons possessing a strong penetrating capability. A sequence of entangled photons emitted by DNA should carry the genetic information encoded by the cordons. This mechanism, predicted in BSM-SG theory, is very important for intercommunication between the cells of the living organism. The next upper level of energy organization may exist in the brain. The brain is an organ of a most abundant number of atomic rings, while its tissue environment might permit complex energy interactions. The human brain contains billions of atomic rings. The next hypothetical upper level of energy organization is an information field, physically existed outside, but connected with the living brain. It corresponds to a specific field known as aura, while the possibility of its existence is still not accepted by the main stream science. The problem is that this field could not be detected by the currently existing technical means used for EM communications. The BSM-SG predicts that this field might differ from the EM field we use for communication, but it is a subject of a further theoretical development that must be supported by experiments using specifically designed technical means. According to the BSM-SG theory, the energy conversion from the primary energy source to the complex levels of matter and field organization is a permanent syntropic process based on complex resonance interactions. (shrink)

Traditional ideas of mediator neutrality and impartiality have come under increasing attack in recent decades. There is, however, a lack of consensus on what should replace them. Mediation Ethics offers a response to this question, developing a new theory of mediation that emphasises its nature as a relational process.

Recently, there has been a surge of interest in the lexicon. The demand for a fuller and more adequate understanding of lexical meaning required by developments in computational linguistics, artificial intelligence, and cognitive science has stimulated a refocused interest in linguistics, psychology, and philosophy. Different disciplines have studied lexical structure from their own vantage points, and because scholars have only intermittently communicated across disciplines, there has been little recognition that there is a common subject matter. The conference on which this (...) volume is based brought together interested thinkers across the disciplines of linguistics, philosophy, psychology, and computer science to exchange ideas, discuss a range of questions and approaches to the topic, consider alternative research strategies and methodologies, and formulate interdisciplinary hypotheses concerning lexical organization. The essay subjects discussed include: * alternative and complementary conceptions of the structure of the lexicon, * the nature of semantic relations and of polysemy, * the relation between meanings, concepts, and lexical organization, * critiques of truth-semantics and referential theories of meaning, * computational accounts of lexical information and structure, and * the advantages of thinking of the lexicon as ordered. (shrink)

ABSTRACT:Organization theory and business ethics are essentially the positive and normative sides of the very same coin, reflecting on how human cooperative activities are organized and how they ought to be organized respectively. It is therefore unfortunate that—due to the relatively impermeable manmade boundaries segregating the corresponding scholarly communities into separate schools and departments, professional associations, and scientific journals—the potential symbiosis between the two fields has not yet fully materialized. In this essay we make a modest attempt at (...) establishing further connectivity by surveying the terrain covered by the two disciplines jointly, as if the boundaries between them did not matter. We commence by providing a concise overview of the organization theory discipline for interested non-specialists from the field of business ethics. Next, we proceed to point out four research themes commonly investigated by members of both communities, and also a variety of organization-theoretical perspectives on each. In the final part of this essay we explore what organization theory has to offer business ethics, and what the boundaries of that potential contribution are. We warn skeptical readers in advance that the spirit and tone of our essay is most definitely upbeat, as we are convinced that the potential for symbiosis between the two fields is vast and inspiring, even though it has only been unleashed partially and incidentally thus far. (shrink)

Organization and management theory as a field faces criticisms from several scholars that it has an unhealthy obsession with ‘theory’, while at the same time seeing very little cumulative theoretical progress. Some have even accused the field of being mired in the 1970s. Lounsbury and Beckman counter with an expansive review of several thriving domains of contemporary organizational research that demonstrate the theoretical vibrancy of the field. This article responds by seeking to define ‘theoretical (...) progress’ in ways that extend beyond just the volume of articles produced. It finds that 1970s‐era classics have seen a surge of citations since the turn of the twenty‐first century, consistent with a view of limited progress. It concludes by outlining three areas of problem‐driven research eminently worthy of attention from organizational researchers. (shrink)

The collaboration of Language and Computing nv (L&C) and the Institute for Formal Ontology and Medical Information Science (IFOMIS) is guided by the hypothesis that quality constraints on ontologies for software ap-plication purposes closely parallel the constraints salient to the design of sound philosophical theories. The extent of this parallel has been poorly appreciated in the informatics community, and it turns out that importing the benefits of phi-losophical insight and methodology into application domains yields a variety of improvements. L&C’s LinKBase® (...) is one of the world’s largest medical domain ontologies. Its current primary use pertains to natural language processing ap-plications, but it also supports intelligent navigation through a range of struc-tured medical and bioinformatics information resources, such as SNOMED-CT, Swiss-Prot, and the Gene Ontology (GO). In this report we discuss how and why philosophical methods improve both the internal coherence of LinKBase®, and its capacity to serve as a translation hub, improving the interoperability of the ontologies through which it navigates. (shrink)

A correspondence theory of truth explains truth in terms of various correspondence relations (e.G., Reference) between words and the extralinguistic world. What are the consequences of quine's doctrine of indeterminacy for correspondence theories? in "ontological relativity" quine implicitly claims that correspondence theories are impossible; that is what the doctrine of 'relative reference' amounts to. But quine's doctrine of relative reference is incoherent. Those who think the indeterminacy thesis valid should not try to relativize reference, They should abandon the relation (...) and replace it by certain more general correspondence relations between words and extralinguistic objects. Doing so will not interfere with the task of defining truth in terms of correspondence relations. (shrink)

The naive theory of properties states that for every condition there is a property instantiated by exactly the things which satisfy that condition. The naive theory of properties is inconsistent in classical logic, but there are many ways to obtain consistent naive theories of properties in nonclassical logics. The naive theory of classes adds to the naive theory of properties an extensionality rule or axiom, which states roughly that if two classes have exactly the same members, (...) they are identical. In this paper we examine the prospects for obtaining a satisfactory naive theory of classes. We start from a result by Ross Brady, which demonstrates the consistency of something resembling a naive theory of classes. We generalize Brady’s result somewhat and extend it to a recent system developed by Andrew Bacon. All of the theories we prove consistent contain an extensionality rule or axiom. But we argue that given the background logics, the relevant extensionality principles are too weak. For example, in some of these theories, there are universal classes which are not declared coextensive. We elucidate some very modest demands on extensionality, designed to rule out this kind of pathology. But we close by proving that even these modest demands cannot be jointly satisfied. In light of this new impossibility result, the prospects for a naive theory of classes are bleak. (shrink)

Nonclassical theories of truth that take truth to be transparent have some obvious advantages over any classical theory of truth. But several authors have recently argued that there’s also a big disadvantage of nonclassical theories as compared to their “external” classical counterparts: proof-theoretic strength. While conceding the relevance of this, the paper argues that there is a natural way to beef up extant internal theories so as to remove their proof-theoretic disadvantage. It is suggested that the resulting internal theories (...) are preferable to their external counterparts. (shrink)

If properties are to play a useful role in semantics, it is hard to avoid assuming the naïve theory of properties: for any predicate Θ(x), there is a property such that an object o has it if and only if Θ(o). Yet this appears to lead to various paradoxes. I show that no paradoxes arise as long as the logic is weakened appropriately; the main difficulty is finding a semantics that can handle a conditional obeying reasonable laws without engendering (...) paradox. I employ a semantics which is infinite-valued, with the values only partially ordered. Can the solution be adapted to naïve set theory? Probably not, but limiting naïve comprehension in set theory is perfectly satisfactory, whereas this is not so in a property theory used for semantics. (shrink)

Bayesian decision theory can be viewed as the core of psychological theory for idealized agents. To get a complete psychological theory for such agents, you have to supplement it with input and output laws. On a Bayesian theory that employs strict conditionalization, the input laws are easy to give. On a Bayesian theory that employs Jeffrey conditionalization, there appears to be a considerable problem with giving the input laws. However, Jeffrey conditionalization can be reformulated so (...) that the problem disappears, and in fact the reformulated version is more natural and easier to work with on independent grounds. (shrink)

This paper is concerned with the debate between substantival and relational theories of space-time, and discusses two difficulties that beset the relationalist: a difficulty posed by field theories, and another difficulty called the problem of quantities. A main purpose of the paper is to argue that possibility can not always be used as a surrogate of ontology, and that in particular that there is no hope of using possibility to solve the problem of quantities.

Any theory of truth must find a way around Curry’s paradox, and there are well-known ways to do so. This paper concerns an apparently analogous paradox, about validity rather than truth, which JC Beall and Julien Murzi call the v-Curry. They argue that there are reasons to want a common solution to it and the standard Curry paradox, and that this rules out the solutions to the latter offered by most “naive truth theorists.” To this end they recommend a (...) radical solution to both paradoxes, involving a substructural logic, in particular, one without structural contraction. In this paper I argue that substructuralism is unnecessary. Diagnosing the “v-Curry” is complicated because of a multiplicity of readings of the principles it relies on. But these principles are not analogous to the principles of naive truth, and taken together, there is no reading of them that should have much appeal to anyone who has absorbed the morals of both the ordinary Curry paradox and the second incompleteness theorem. (shrink)

1. Of what use is the concept of causation? Bertrand Russell [1912-13] argued that it is not useful: it is “a relic of a bygone age, surviving, like the monarchy, only because it is erroneously supposed to do no harm.” His argument for this was that the kind of physical theories that we have come to regard as fundamental leave no place for the notion of causation: not only does the word ‘cause’ not appear in the advanced sciences, but the (...) laws that these sciences state are incompatible with causation as we normally understand it. But Nancy Cartwright has argued [1979] that abandoning the concept of causation would cripple science; her conclusion was based not on fundamental physics, but on more ordinary science such as the search for the causes of cancer. She argues that Russell was right that the fundamental theories of modern physics say nothing, even implicitly, about causation, and concludes on this basis that such theories are incomplete. It is with this cluster of issues that I will begin my discussion. (shrink)

This book offers a detailed study of the political philosophies of Thomas Hobbes and Benedict de Spinoza, focussing on their concept of power as potentia, concrete power, rather than power as potestas, authorised power. The focus on power as potentia generates a new conception of popular power. Radical democrats–whether drawing on Hobbes's 'sleeping sovereign' or on Spinoza's 'multitude'–understand popular power as something that transcends ordinary institutional politics, as for instance popular plebsites or mass movements. However, the book argues that these (...) understandings reflect a residual scholasticism which Hobbes and Spinoza ultimately repudiate. Instead, on the book's revisionist conception, a political phenomenon should be said to express popular power when it is both popular (it eliminates oligarchy and encompasses the whole polity), and also powerful (it robustly determines political and social outcomes). Two possible institutional forms that this popular power might take are distinguished: Hobbesian repressive egalitarianism, or Spinozist civic strengthening. But despite divergent institutional proposals, the book argues that both Hobbes and Spinoza share the conviction that there is nothing spontaneously egalitarian or good about human collective existence. From this point of view, the book accuses radical democrats of pernicious romanticism; the slow, meticulous work of organizational design and maintenance is the true centre of popular power. Three minute video summary available via HPBin3. Extended discussion on The Political Theory Review podcast. First chapter open access available via Oxford Scholarship Online. Videos of book talks at National University of Singapore (Centre for Legal Theory) and Universidad de Buenos Aires (Instituto de Investigaciones Gino Germani) available via YouTube. (See links below.). (shrink)

This paper extends Kripke’s theory of truth to a language with a variably strict conditional operator, of the kind that Stalnaker and others have used to represent ordinary indicative conditionals of English. It then shows how to combine this with a different and independently motivated conditional operator, to get a substantial logic of restricted quantification within naive truth theory.

The term ‘social capital’ is a way of defining the intangible resources of community, shared values and trust upon which we draw in daily life. It has achieved considerable international currency across the social sciences through the very different work of Pierre Bourdieu in France and James Coleman and Robert Putnam in the United States, and has been widely taken up within politics and sociology as an explanation for the decline in social cohesion and community values in western societies. It (...) has also been adopted by policy makers, particularly in international governmental bodies such as the World Bank. (shrink)

The paper offers a solution to the semantic paradoxes, one in which (1) we keep the unrestricted truth schema “True(A)↔A”, and (2) the object language can include its own metalanguage. Because of the first feature, classical logic must be restricted, but full classical reasoning applies in “ordinary” contexts, including standard set theory. The more general logic that replaces classical logic includes a principle of substitutivity of equivalents, which with the truth schema leads to the general intersubstitutivity of True(A) with (...) A within the language.The logic is also shown to have the resources required to represent the way in which sentences (like the Liar sentence and the Curry sentence) that lead to paradox in classical logic are “defective”. We can in fact define a hierarchy of “defectiveness” predicates within the language. Contrary to claims that any solution to the paradoxes just breeds further paradoxes (“revenge problems”) involving defectiveness predicates, there is a general consistency/conservativeness proof that shows that talk of truth and the various “levels of defectiveness” can all be made coherent together within a single object language. (shrink)

De Re Significance accounts of moral appraisal consider an agent’s responsiveness to a particular kind of reason, normative moral reasons de re, to be of central significance for moral appraisal. Here, I argue that such accounts find it difficult to accommodate some neuroatypical agents. I offer an alternative account of how an agent’s responsiveness to normative moral reasons affects moral appraisal – the Reasonable Expectations Account. According to this account, what is significant for appraisal is not the content of the (...) reasons an agent is responsive to, but rather whether she is responsive to the reasons it is reasonable to expect her to be responsive to, irrespective of their content. I argue that this account does a better job of dealing with neuroatypical agents, while agreeing with the De Re Significance accounts on more ordinary cases. (shrink)

Software application ontologies have the potential to become the keystone in state-of-the-art information management techniques. It is expected that these ontologies will support the sort of reasoning power required to navigate large and complex terminologies correctly and efficiently. Yet, there is one problem in particular that continues to stand in our way. As these terminological structures increase in size and complexity, and the drive to integrate them inevitably swells, it is clear that the level of consistency required for such navigation (...) will become correspondingly difficult to maintain. While descriptive semantic representations are certainly a necessary component to any adequate ontology-based system, so long as ontology engineers rely solely on semantic information, without a sound ontological theory informing their modeling decisions, this goal will surely remain out of reach. In this paper we describe how Language and Computing nv (L&C), along with The Institute for Formal Ontology and Medical Information Sciences (IFOMIS), are working towards developing and implementing just such a theory, combining the open software architecture of L&C’s LinkSuiteTM with the philosophical rigor of IFOMIS’s Basic Formal Ontology. In this way we aim to move beyond the more or less simple controlled vocabularies that have dominated the industry to date. (shrink)

The paper distinguishes two approaches to understanding the representational content of sentences and intentional states, and its role in describing people, predicting and explaining their behavior, and so forth. It sets forth the case for one of these approaches, the “egocentric” one, initially on the basis of its ability to explain the near‐indefeasibility of ascriptions of content to our own terms (“‘dogs’ as I use it means dogs”), but more generally on the basis of its providing an attractive overall picture (...) of the descriptive and explanatory role of representational content. In doing this, the paper relates the egocentric view to an “immanent” or “deflationary” view of reference and truth conditions, and also to the view of reference‐talk and truth‐talk as anaphoric devices. It discusses the indeterminacy of content ascriptions to those in communities with radically different theories, a phenomenon that is unsurprising on the egocentric approach, and connects this to the thesis of the normativity of meaning. (It does all this in rather broad brush: many strands of the egocentric account will be familiar, and are the subject of familiar controversies; the point of the paper is less to address these controversies individually than to tie the strands together into what is hoped to be an appealing package.). (shrink)

It might be thought that we could argue for the consistency of a mathematical theory T within T, by giving an inductive argument that all theorems of T are true and inferring consistency. By Gödel's second incompleteness theorem any such argument must break down, but just how it breaks down depends on the kind of theory of truth that is built into T. The paper surveys the possibilities, and suggests that some theories of truth give far more intuitive (...) diagnoses of the breakdown than do others. The paper concludes with some morals about the nature of validity and about a possible alternative to the idea that mathematical theories are indefinitely extensible. (shrink)

An interpretation of Berkeley’s theory of meaning must account for operative utility as well as Berkeley’s commitment to the truth of Christian scriptures. I argue that formalist and use-theoretic...

While non-classical theories of truth that take truth to be transparent have some obvious advantages over any classical theory that evidently must take it as non-transparent, several authors have recently argued that there's also a big disadvantage of non-classical theories as compared to their “external” classical counterparts: proof-theoretic strength. While conceding the relevance of this, the paper argues that there is a natural way to beef up extant internal theories so as to remove their proof-theoretic disadvantage. It is suggested (...) that the resulting internal theories should seem preferable to their external counterparts. (shrink)

Both in dealing with the semantic paradoxes and in dealing with vagueness and indeterminacy, there is some temptation to weaken classical logic: in particular, to restrict the law of excluded middle. The reasons for doing this are somewhat different in the two cases. In the case of the semantic paradoxes, a weakening of classical logic (presumably involving a restriction of excluded middle) is required if we are to preserve the naive theory of truth without inconsistency. In the case of (...) vagueness and indeterminacy, there is no worry about inconsistency; but a central intuition is that we must reject the factual status of certain sentences, and it hard to see how we can do that while claiming that the law of excluded middle applies to those sentences. So despite the different routes, we have a similar conclusion in the two cases. (shrink)

The American tradition of action theory failed to produce a useful theory of the possible existence of trans-individual consistencies in sexual desirability. Instead, most sociological theorists have relied on market metaphors to account for the logic of sexual action. Through a critical survey of sociological attempts to explain the social organization of sexual desiring, this article demonstrates that the market approach is inadequate, and that its inadequacies can be remedied by studying sexual action as occurring within a (...) specifically sexual field , with a correlative sexual capital. Such a conception allows for historical and comparative analysis of changes in the organization of sexual action that are impeded by the use of a market metaphor, and also points to difficulties in Bourdieu's own treatment of the body qua body. (shrink)

The paper shows how we can add a truth predicate to arithmetic (or formalized syntactic theory), and keep the usual truth schema Tr( ) ↔ A (understood as the conjunction of Tr( ) → A and A → Tr( )). We also keep the full intersubstitutivity of Tr(>A>)) with A in all contexts, even inside of an →. Keeping these things requires a weakening of classical logic; I suggest a logic based on the strong Kleene truth tables, but with (...) → as an additional connective, and where the effect of classical logic is preserved in the arithmetic or formal syntax itself. Section 1 is an introduction to the problem and some of the difficulties that must be faced, in particular as to the logic of the →; Section 2 gives a construction of an arithmetically standard model of a truth theory; Section 3 investigates the logical laws that result from this; and Section 4 provides some philosophical commentary. (shrink)

Argues that there are two reasons for ascribing to mental states, structures more fine-grained than the sets of possible world they represent: first, fine-grained structure enters naturally into the explanation of behaviour; second, fine-grained structure is needed in a theory of how those states represent the sets of possible worlds they represent. In connection with the first point, it is argued that Stalnaker’s attempt to use metalinguistic content to obviate the need of fine-grained structure cannot work. In connection with (...) the second point, it is argued that the systematicity in the assignment of content to mental states can be accommodated only by postulating a fine-grained structure for mental states. Also contains some discussion of doing without representational content, understood in the non-deflationary sense that Stalnaker assumes. (shrink)

I propose a theory of popular power, according to which a political order manifests popular power to the extent it robustly maintains an egalitarian basic structure. There are two parts to the theory. First, the power of a political order lies in the basic structure's robust self-maintenance. Second, the popularity of the political order’s power lies in the equality of relations between the society's members. I will argue that this theory avoids the perverse consequences of some existing (...) radical democratic theories of popular power which focus on mass expression, either in plebiscites or in social movements, as popular power's canonical instances. In particular, my theory does not valourise momentary expression over durable effect, and it offers a ready framework for conceptualising the sometimes-oligarchic substructure of the supposedly canonical instances of popular power. I will show that this theory has strong precedents within a certain republican tradition of political philosophy. (shrink)

There are close affinities between James' theory of time as discussed in A Pluralistic Universe and the so-called epochal theory of time offered by Alfred North Whitehead. In this paper I examine James' theory and compare it with the views of Henri Bergson.

Negri celebrates a conception of democracy in which the concrete powers of individual humans are not alienated away, but rather are added together: this is a democracy of the multitude. But how can the multitude act without alienating anyone’s power? To answer this difficulty, Negri explicitly appeals to Spinoza. Nonetheless, in this paper, I argue that Spinoza’s philosophy does not support Negri’s project. I argue that the Spinozist multitude avoids internal hierarchy through the mediation of political institutions and not in (...) spite of them; nor do these institutions merely emanate from the multitude as it is, but rather they structure, restrain and channel its passions. In particular, the required institutions are not those of a simple direct democracy. There may be other non-Spinozist arguments on which Negri can ground his theory, but he cannot legitimately defend his conception of the democratic multitude by appeal to Spinoza. (shrink)