At War with War visualizes humanity's 5,000-year-long state of conflict, chaos, and violence on a continuous timeline. Seventy pages of stark black-and-white pen-and-ink drawings and woodcuts illustrate history's most notorious battles -- from 3300 BCE to the present day. Interspersed are contemplations on war from historic thinkers, including excerpts from "The Art of War" by Sun Tsu, "The Complaint of Peace" by Desiderius Erasmus, and "The State" by Randolph Bourne. Searing and sardonic, balancing anger and despair with wit and humanity, (...) these raw illustrations follow in the tradition of great social satirists such as Honoré Daumier, Frans Masereel, Felix Vallotton, and Otto Dix. Seymour Chwast is a design legend. As co-founder with Milton Glaser of Push Pin Studios, he led a revolution in graphic design in the 1960s and '70s, producing bold, vibrant work that pushed the limits of nearly every visual medium.Now, he turns his pen and sketchpad toward creating a new book on a subject that has been a personal obsession for nearly six decades: the fight against war, humankind's never-ending scourge. (shrink)

Targeted hypermutation has proven to be a useful survival strategy for bacteria under severe stress and is also used by multicellular organisms in specific instances such as the mammalian immune system. This might appear surprising, given the generally observed deleterious effects of poor replication fidelity/high mutation rate. A previous theoretical model designed to explore the role of replication fidelity in the origin of life was applied to a simulated hypermutation scenario. The results confirmed that the same model is useful for (...) analyzing hypermutation and can predict the effects of the same parameters (survival probability, replication fidelity, mutation effect, and others) on the survival of cellular populations undergoing hypermutation as a result of severe stress. (shrink)

Though the publication of Kuhn's 'Structure of Scientific Revolutions' seemed to herald the advent of a unified study of the history and philosophy of science, it is a hard fact that history of science and philosophy of science have increasingly grown apart. Recently, however, there has been a series of workshops on both sides of the Atlantic (called '&HPS') to bring historians and philosophers of science together to discuss integrative approaches. This is therefore an especially appropriate time to explore the (...) problems with and prospects for integrating history and philosophy of science. The original essays in this volume, all from specialists in the history of science or philosophy of science, offer such an exploration from a wide variety of perspectives. The volume combines general reflections on the current state of history and philosophy of science with discussion of the relation between the two disciplines in specific historical and scientific cases"--Publisher's description, back cover. (shrink)

Evolution in modern life requires high replication fidelity to allow for natural selection. A simulation model utilizing simulated phenotype data on cellular probability of survival was developed to determine how self-replication fidelity could evolve in early life. The results indicate that initial survivability and replication fidelity both contribute to overall fitness as measured by growth rates of the cell population. Survival probability was the more dominant feature, and evolution was possible even with zero replication fidelity. A derived formula for the (...) relationship of survival probability and replication fidelity with growth rate was consistent with the simulated empirical data. Quantitative assessment of continuity and other evidence was obtained for a saltation evolutionary process starting from low to moderate levels of survival probability and self-replication fidelity to reach the high levels seen in modern life forms. (shrink)

Ernst Cassirer: Scientific Knowledge and the Concept of Man by Seymour W. Itzkoff is currently one of the few books available in the English language that discusses the philosophy of twentieth-century German philosopher Ernst Cassirer. Itzkoff's study brings Cassirer's perspective directly into the contemporary debate over the evolution of human thought and its relationship to animal life. Further, Itzkoff places Cassirer directly in the context of recent philosophical thought, arguing for the importance of his Kantian perspective, a significance that (...) is amply vindicated by the current interest in Cassirer's ideas. For this second edition, Seymour has written a new introduction and has added a new retrospective essay. (shrink)

Closely related to this is Mr. Bruner's "evolutionary instrumentalism," his conception of instruction as the means of transmitting the tools and skills of a ...

A thorough analysis of Tocqueville's thoughts on the lower classes of society, viewing his stances on slavery, poverty, criminality, and working class ...

Eric Williams's Capitalism and Slavery is a classic in the sense that it irreversyibly altered our most basic way of looking at an historical event. Writing the book in 1944, Williams broke with the century of histories portraying the British abolition of slavery as a humanist event, a moral victory. His account of slavery in the British colonies was innovative in introducing the notion that economic, rather than moral, factors were decisive in the motivation and success of the abolitionists. The (...) two farthest-reaching claims of Capitalism and Slavery are that British colonial slave production and the slave trade enabled the industrial revolution to take place in Britain, and that the abolition movement resulted solely from changes in the British imperial economy. Though few historians since Williams have agreed with him on the centrality of industrialization in the slave colonies and abolition, his work has resulted in the inclusion of economic factors in all recent accounts of slavery and its abolition. By writing a simplistic history with a global context, Williams made it impossible for subsequent historians to write about abolition as an isolated moral act of the British Empire. (shrink)

Some incompatibilists about free will or moral responsibility and determinism would abandon their incompatibilism were they to learn that determinism is true. But is it reasonable to flip-flop in this way? In this article, we contend that it is and show what follows. The result is both a defense of a particular incompatibilist strategy and a general framework for assessing other cases of flip-flopping.