Examining a variety of bio-objects in contexts beyond the laboratory, Bio-Objects: Life in the 21st Century explores new ways of thinking about how novel bio-objects enter contemporary life, analysing the manner in which the boundaries between human and animal, organic and non-organic, and being 'alive' and the suspension of living, are questioned, destabilised and in some cases re-established.

The article deals with semiosis and its dimensions as a theoretical construct to show some elementary differences between spheres of semiotic activity. In essence, one sign will be dissected into four categories of existence to show it may have different relations depending on the dimension it happens to be in. The general framework is that of human consciousness and its two distinct states: awake cognition and asleep dreaming with emphasis on the latter. From our point of view, the concepts of (...) ‘nature’ and ‘culture’ have two layers: the manifest form and the latent function, the seen and the unseen. These are used as parallels to support the central thesis of this article that human cognition has dreaming as its countepart.The main theoretical frame is drawn from the work of Greimas and Courtes with emphasis on the semiotic square. The concept of the sign is taken from Peirce, whereas ‘sign-ness’ is adopted from Pyatigorskij. By projecting the triadic sign onto the semiotic square and excluding the concept ‘sign system’ along with the syntactic aspect, the basic fourfold dimension of the sign as such will be brought to view based on the distinct sign-relations in each given dimension. In order to double the square, semiosis will be endowed with features of ‘being-able’, thus affording the initial expression of dominant modalities serving as basis for the structure(s) of the elementary function and mechanism in each of the four dimensions. This will also enable bringing into view some elementary restrictions on semiosis in each dimension. Lastly, some new terms are suggested in accordance with what has been presented.В статье рассматривается семиозис и его измерения как теоретическая конструкция, чтобы показать некоторые элементарные различия между сферами семиотического действия. По сути знак будет разделен на четыре категории существования, чтобы показать, что он может иметь разные отношения в зависимости от того, в каком измерении он находится. Основной рамкой, вместе с тем, является человеческое сознание в его двух состояниях: в состоянии бодрствования и сна со сновидениями, с акцентом на последнее. Несмотря на широкое использование универсальных понятий ‘природа’ и ‘культура’, статья не сосредоточивается на семиотических особенностях этих доменов. С нашей точки зрения ‘природа’ и ‘культура’ имеют два уровня, т.е. проявленную форму и скрытую функцию, видимое и невидимое. Они используются параллельно, поддерживая центральный тезис этой статьи о том, что человеческое познание имеет соответствие в виде сновидения.Теоретическая рамка взята из работы Греймаса и Курте с акцентом на семиотический квадрат. Понятие знака трактуется в духе Пирса, тогда как понятие ≪знаковости≫ дается по Пятигорскому. При проекции триадического знака на семиотический квадрат и исключении понятия ≪знаковой системы≫ вместе с синтаксическим аспектом, обнаруживается основное четырехкратное измерение знака, опирающаяся на определенные знаковые отношения в каждом данном измерении. Чтобы удвоить квадрат, семиозис будет наделен функцией ≪быть способным≫, таким образом обеспечивая начальное выражение доминирующих модальностей, служащих в каждом из четырых измерений основой для структуры (структур) элементарной функции и механизма. Это также даст возможность рассмотреть некоторые элементарные ограничения семиозиса в каждом из измерений. Наконец, предлагаются некоторые новые термины в соответствии с тем, что было представлено.Artikkel tegeleb semioosi ja selle mootmetega kui teoreetilise konstruktsiooniga, et demonstreerida moningaid elementaarseid erinevusi semiootilise tegevuse sfaarides. Sisuliselt lahatakse uks mark neljaks eksistentsikategooriaks, naitamaks, et sel voivad olla erinevad suhted olenevalt mootmest, milles see olema juhtub. Uldiseks raamiks on inimteadvus ja selle kaks eristuvat olekut: arkvelolek ja uni, rohuasetusega viimasel. Vaatamata universaalsete terminite nagu ‘loodus’ ja ‘kultuur’ ohtrale kasutamisele, ei tegele kaesolev artikkel nende valdkondade semiootiliste eriparadega. Meie seisukohast on ‘loodusel’ ja ‘kultuuril’ kaks kihti – manifestne vorm ja latentne funktsioon, nahtav ja nahtamatu. Neid vaadeldakse paralleelselt, et toetada kaesoleva artikli keskset teesi, et inimkognitsiooni vasteks on unenagemine.Peamine teoreetiline raam tuleneb Greimase ja Courtes’ toodest, rohuasetusega semiootilisele ruudule. Margi moiste voetakse Peirce’ilt ning “margilisus” Pjatigorskilt. Projitseerides triaadilist marki semiootilisele ruudule ning valistades ‘margisusteemi’ moiste koos suntaktilise aspektiga, tuuakse nahtavale margi neljakordne alusdimensioon, mis tugineb kindlatele margisuhetele igas antud mootmes. Et ruutu kahekordistada, antakse semioosile ‘suutlikkuse’ jooned, lubades domineerivate modaalsuste algset valjendumist, mis igas neljast dimensioonist toimivad elementaarse funktsiooni struktuuri(de) ja mehhanismi alusena. See voimaldab vaatluse alla tuua ka moned elementaarsed piirangud semioosile iga dimensioonis. Viimaks pakutakse valja moned uued terminid. (shrink)

Recently, a three-dimensional construct model for complex experiential Selfhood has been proposed (Fingelkurts et al., 2016b,c). According to this model, three specific subnets (or modules) of the brain self-referential network (SRN) are responsible for the manifestation of three aspects/features of the subjective sense of Selfhood. Follow up multiple studies established a tight relation between alterations in the functional integrity of the triad of SRN modules and related to them three aspects/features of the sense of self; however, the causality of this (...) relation is yet to be shown. In this article we approached the question of causality by exploring functional integrity within the three SRN modules that are thought to underlie the three phenomenal components of Selfhood while these components were manipulated mentally by experienced meditators in a controlled and independent manner. Participants were requested, in a block-randomised manner, to mentally induce states representing either increased (up-regulation) or decreased (down-regulation) sense of (a) witnessing agency (“Self”), or (b) body representational-emotional agency (“Me”), or (c) reflective/narrative agency (“I”), while their brain activity was recorded by an electroencephalogram (EEG). This EEG-data was complemented by first-person phenomenological reports and standardised questionnaires which focused on subjective contents of three aspects of Selfhood. The results of the study strengthen the case for a direct causative relationship between three phenomenological aspects of Selfhood and related to them three modules of the brain SRN. Furthermore, the putative integrative model of the dynamic interrelations among three modules of the SRN has been proposed. (shrink)

Using theoretical analysis of self-consciousness concept and experimental evidence on the brain default mode network (DMN) that constitutes the neural signature of self-referential processes, we hypothesized that the anterior and posterior subnets comprising the DMN should show differences in their integrity as a function of meditation training. Functional connectivity within DMN and its subnets (measured by operational synchrony) has been measured in ten novice meditators using an electroencephalogram (EEG) recording in a pre-/post-meditation intervention design. We have found that while the (...) whole DMN was clearly suppressed, different subnets of DMN responded differently after 4 months of meditation training: The strength of EEG operational synchrony in the right and left posterior modules of the DMN decreased in resting post-meditation condition compared to a pre-meditation condition, whereas the frontal DMN module on the contrary exhibited an increase in the strength of EEG operational synchrony. These findings combined with published data on functional–anatomic heterogeneity within the DMN and on trait subjective experiences commonly found following meditation allow us to propose that the first-person perspective and the sense of agency (the witnessing observer) are presented by the frontal DMN module, while the posterior modules of the DMN are generally responsible for the experience of the continuity of ‘I’ as embodied and localized within bodily space. Significance of these findings is discussed. (shrink)

Based on the finding in novices that four months of meditation training significantly increases frontal default mode network (DMN) module/subnet synchrony while decreasing left and right posterior DMN modules synchrony, the current study tested the prediction whether experienced meditators (those who are practising meditation intensively for several years) had a change in the DMN “trinity” of modules as a baseline trait characteristic and whether this change is in a similar direction as in the novice trainees who practised meditation for only (...) four months. Comparison of functional connectivity within DMN subnets (measured by electroencephalogram operational synchrony in the three separate DMN modules) between five experienced meditators and 10 naïve participants (who were about to start the meditation training) fully support the prediction. Interpretation that links such DMN subnets changes to the three-dimensional components of the experiential selfhood was proposed. (shrink)

The therapeutic potential of meditation for physical and mental well-being is well documented, however the possibility of adverse effects warrants further discussion of the suitability of any particular meditation practice for every given participant. This concern highlights the need for a personalized approach in the meditation practice adjusted for a concrete individual. This can be done by using an objective screening procedure that detects the weak and strong cognitive skills in brain function, thus helping design a tailored meditation training protocol. (...) Quantitative electroencephalogram (qEEG) is a suitable tool that allows identification of individual neurophysiological types. Using qEEG screening can aid developing a meditation training program that maximizes results and minimizes risk of potential negative effects. This brief theoretical–conceptual review provides a discussion of the problem and presents some illustrative results on the usage of qEEG screening for the guidance of mediation personalization. (shrink)

This paper argues that to progress with philosophical issues concerning brain-mind relations one needs to combine philosophical reflection and empirical research with theoretical model building. Philosophy and abstract theorizing alone do not carry us far, as will be illustrated by analyzing the views about panpsychism by the quantum physicist David Bohm, who builds his reasoning on quantum mechanical analogies. His reflection around the notion of active information, adopted in his causal interpretation of quantum mechanics to replace the Newtonian notion of (...) force, turns out to be a fallacy of equivocation. His other line of reasoning to specify matter-mind unity in terms of soma-significance and signa-somatic processes yields problems of its own. To illustrate empirical investigations on brain-mind relations, I shall present the tripartite model of the experiential selfhood and the related Self-Me-I index as proposed by the neuroscientists Fingelkurts and Fingelkurts, along with their background theory called operational architectonics (OA) of brain-mind functioning. The model states that the three components of selfhood, Self, Me, and I, correlate to three distinct operationally synchronized cortical areas, the frontal cortex, the right posterior cortex, and the left posterior cortex. The philosophical and practical benefits of their framework will be exemplified by presenting the results of a series of studies with the philosopher Tarja Kallio-Tamminen about the effects of meditation reflected in the Self-Me-I index. (shrink)

Genes, Cells and Brains: The Promethean Promises of the New Biology Hillary Rose & Stephen Rose, Genes, Cells and Brains: The Promethean Promises of the New Biology. London and New York: Verso Books, 2014. ISBN-10: 178168314X (paperback). 336 pp. -/- Bio-Objects: Life in the 21st Century Niki Vermeulen, Sakari Tamminen & Andrew Webster (eds) Bio-Objects: Life in the 21st Century. Farnham, Surrey: Ashgate, 2012. ISBN: 978-1-4094-1178-9 (hardback). 240 pp.