Results for 'Targeting'

1000+ found
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  1.  26
    Narrative Theology and Moral Theology: the Infinite Horizon. By Alexander Lucie-Smith.Laurence Target - 2010 - Heythrop Journal 51 (2):344-346.
  2.  8
    ‘I Just Stopped Going’: A Mixed Methods Investigation Into Types of Therapy Dropout in Adolescents With Depression.Sally O’Keeffe, Peter Martin, Mary Target & Nick Midgley - 2019 - Frontiers in Psychology 10.
    What does it mean to ‘drop out’ of therapy? Many definitions of ‘dropout’ have been proposed, but the most widely accepted is the client ending treatment without agreement of their therapist. However, this is in some ways an external criterion that does not take into account the client’s experience of therapy, or reasons for ending it prematurely. This study aimed to identify whether there were more meaningful categories of dropout than the existing dropout definition, and to test whether this refined (...)
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  3.  20
    Maternal and Child Sexual Abuse History: An Intergenerational Exploration of Children’s Adjustment and Maternal Trauma-Reflective Functioning.Jessica L. Borelli, Chloe Cohen, Corey Pettit, Lina Normandin, Mary Target, Peter Fonagy & Karin Ensink - 2019 - Frontiers in Psychology 10.
    Objective: The aim of the current study was to investigate associations, unique and interactive, between mothers’ and children’s histories of childhood sexual abuse (CSA) and children’s psychiatric outcomes using an intergenerational perspective. Further, we were particularly interested in examining whether maternal reflective functioning about their own trauma (T-RF) was associated with lower likelihood of children’s abuse exposure (among children of CSA-exposed mothers). Method: One hundred and eleven children (Mage= 9.53 years; 43 sexual abuse victims) and their mothers (Mage= 37.99; 63 (...)
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  4.  18
    Moving Targets and Models of Nothing: A New Sense of Abstraction for Philosophy of Science.Michael T. Stuart & Anatolii Kozlov - 2024 - In Chiara Ambrosio & Julia Sánchez-Dorado (eds.), Abstraction in science and art: philosophical perspectives. New York, NY: Routledge.
    As Nelson Goodman highlighted, there are two main senses of “abstract” that can be found in discussions about abstract art. On the one hand, a representation is abstract if it leaves out certain features of its target. On the other hand, something can be abstract to the extent that it does not represent a concrete subject. The first sense of “abstract” is well-known in philosophy of science. For example, philosophers discuss mathematical models of physical, biological, and economic systems as being (...)
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  5.  39
    Target Centred Virtue Ethics.Christine Swanton - 2021 - Oxford University Press.
    Christine Swanton presents a new target centred virtue ethics, which is opposed to orthodox virtue ethics in two major ways. She rejects the 'natural goodness' metaphysics of neo-Aristotelian virtue ethics in favour of a 'hermeneutic ontology' of ethics, and she offers a new target centred framework for assessing rightness of acts.
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  6. Philosophical intuitions: Their target, their source, and their epistemic status.Alvin I. Goldman - 2007 - Grazer Philosophische Studien 74 (1):1-26.
    Intuitions play a critical role in analytical philosophical activity. But do they qualify as genuine evidence for the sorts of conclusions philosophers seek? Skeptical arguments against intuitions are reviewed, and a variety of ways of trying to legitimate them are considered. A defense is offered of their evidential status by showing how their evidential status can be embedded in a naturalistic framework.
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  7. Representations, Targets, and Attitudes.Robert Cummins - 1996 - MIT Press.
  8. Target-Centred Virtue Ethics: Aristotelian or Confucian?Philippe Brunozzi & Waldemar Brys - forthcoming - Inquiry: An Interdisciplinary Journal of Philosophy:1-22.
    We raise the following problem for so-called target-centred virtue ethics. An important motivation for adopting target-centred virtue ethics over other forms of virtue ethics is its supposedly distinctive account of right action: an action is right if and only if and because it is virtuous, and what makes an action virtuous is that it hits the target of the virtues. We argue that the account is not distinctive of target-centred virtue ethics, because it is an account that is widely endorsed (...)
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  9. Target space ≠ space.Nick Huggett - 2017 - Studies in History and Philosophy of Science Part B: Studies in History and Philosophy of Modern Physics 59:81-88.
    This paper investigates the significance of T-duality in string theory: the indistinguisha- bility with respect to all observables, of models attributing radically different radii to space – larger than the observable universe, or far smaller than the Planck length, say. Two interpretational branch points are identified and discussed. First, whether duals are physically equivalent or not: by considering a duality of the familiar simple harmonic oscillator, I argue that they are. Unlike the oscillator, there are no measurements ‘outside’ string theory (...)
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  10.  12
    Between Collection and Interpretation: Targeted Rights for Unpredictable Insights.Tessa Gavina & Lucas Gutiérrez-Lafrentz - 2024 - American Journal of Bioethics Neuroscience 15 (2):142-144.
    In their paper “Brain Data in Context: Are New Rights the Way to Mental and Brain Privacy?” Susser and Cabrera (2024) argue against the notion that specific rights may be necessary to protect “brai...
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  11. Shifting Targets and Disagreements.Robin McKenna - 2014 - Australasian Journal of Philosophy 92 (4):725-742.
    Many have rejected contextualism about ?knows? because the view runs into trouble with intra- and inter-contextual disagreement reports. My aim in this paper is to show that this is a mistake. First, I outline four desiderata for a contextualist solution to the problem. Second, I argue that two extant solutions to the problem fail to satisfy the desiderata. Third, I develop an alternative solution which satisfies the four desiderata. The basic idea, put roughly, is that ?knowledge? ascriptions serve the function (...)
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  12.  8
    The Targeting System of Language.Leonard Talmy - 2018 - MIT Press.
    In this book, Leonard Talmy proposes that a single linguistic/cognitive system, targeting, underlies two domains of linguistic reference, those termed anaphora and deixis. Talmy argues that language engages the same cognitive system to single out referents whether they are speech-internal or speech-external. Talmy explains the targeting system in this way: as a speaker communicates with a hearer, her attention is on an object to which she wishes to refer; this is her target. To get the hearer's attention on (...)
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  13.  39
    When Targets Strike Back: How Negative Workplace Gossip Triggers Political Acts by Employees.Bao Cheng, Yun Dong, Zhenduo Zhang, Ahmed Shaalan, Gongxing Guo & Yan Peng - 2020 - Journal of Business Ethics 175 (2):289-302.
    This study examines why and when negative workplace gossip promotes self-serving behaviors by the employees being targeted. Using conservation of resources theory, we find that targets tend to increase their political acts as a result of ego depletion triggered by negative gossip. We also show that sensitivity to interpersonal mistreatment and moral disengagement moderate this process. Specifically, we demonstrate that targets with high levels of sensitivity to interpersonal mistreatment are more likely to experience ego depletion, and that targets with high (...)
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  14.  11
    Targeted Killing, Assassination, and the Problem of Dirty Hands.Tamar Meisels - 2023 - The Journal of Ethics 27 (4):585-599.
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  15.  18
    Debating Targeted Killing: Counter-Terrorism or Extrajudicial Execution?Tamar Meisels & Jeremy Waldron - 2020 - Oup Usa.
    Known terrorists are often targeted for death by the governments of Israel and the United States. Several thousand have been killed by drones or by operatives on the ground in the last twenty years. Is this form of killing justified? Is there anything about it that should disturb us? In this for-and-against book, political theorists Jeremy Waldron and Tamar Meisels engage in extended debate to illuminate these issues. They consider the actions of targeting and hunting down named individuals, and (...)
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  16.  41
    Targeted Killings: Law and Morality in an Asymmetrical World.Claire Finkelstein, Jens David Ohlin & Andrew Altman (eds.) - 2012 - Oxford University Press.
    The controversy surrounding targeted killings represents a crisis of conscience for policymakers, lawyers, philosophers and leading military experts grappling with the moral and legal limits of the war on terror. The book examines the legal and philosophical issues raised by government efforts to target suspected terrorists without giving them the safeguards of a fair trial.
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  17. Targeted Killings: Legal and Ethical Justifications.Tomasz Zuradzki - 2015 - In Marcelo Galuppo (ed.), Human Rights, Rule of Law and the Contemporary Social Challenges in Complex Societies. pp. 2909-2923.
    The purpose of this paper is the analysis of both legal and ethical ways of justifying targeted killings. I compare two legal models: the law enforcement model vs the rules of armed conflicts; and two ethical ones: retribution vs the right of self-defence. I argue that, if the targeted killing is to be either legally or ethically justified, it would be so due to fulfilling of some criteria common for all acceptable forms of killing, and not because terrorist activity is (...)
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  18.  19
    Targets of opportunity: on the militarization of thinking.Samuel Weber - 2005 - New York: Fordham University Press.
    The title of this book echoes a phrase used by the Washington Post to describethe American attempt to kill Saddam Hussein at the start of the war againstIraq. Its theme is the notion of targeting (skopos) as the name of an intentionalstructure in which the subject tries to confirm its invulnerability by aiming todestroy a target. At the center of the first chapter is Odysseus’s killing of the suitors;the second concerns Carl Schmitt’s Roman Catholicism and Political Form; thethird and (...)
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  19.  6
    Auditory Target Detection Enhances Visual Processing and Hippocampal Functional Connectivity.Roy Moyal, Hamid B. Turker, Wen-Ming Luh & Khena M. Swallow - 2022 - Frontiers in Psychology 13.
    Though dividing one’s attention between two input streams typically impairs performance, detecting a behaviorally relevant stimulus can sometimes enhance the encoding of unrelated information presented at the same time. Previous research has shown that selection of this kind boosts visual cortical activity and memory for concurrent items. An important unanswered question is whether such effects are reflected in processing quality and functional connectivity in visual regions and in the hippocampus. In this fMRI study, participants were asked to memorize a stream (...)
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  20. Right action and the targets of virtue.Liezl van Zyl - 2014 - In S. van Hooft, N. Athanassoulis, J. Kawall, J. Oakley & L. van Zyl (eds.), The handbook of virtue ethics. Durham: Acumen Publishing.
    A critical discussion of Christine Swanton's target-centred account of right action.
     
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  21.  28
    Targeted killing with drones? Old arguments, new technologies.Tamar Meisels - 2018 - Filozofija I Društvo 29 (1):3-16.
    The question of how to contend with terrorism in keeping with our preexisting moral and legal commitments now challenges Europe as well as Israel and the United States: how do we apply Just War Theory and International Law to asymmetrical warfare, specifically to our counter terrorism measures? What can the classic moral argument in Just and Unjust Wars teach us about contemporary targeted killings with drones? I begin with a defense of targeted killing, arguing for the advantages of pin pointed (...)
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  22.  25
    Targeted Proteomics Comes to the Benchside and the Bedside: Is it Ready for Us?Anjali Arora & Kumaravel Somasundaram - 2019 - Bioessays 41 (2):1800042.
    While mass spectrometry (MS)‐based quantification of small molecules has been successfully used for decades, targeted MS has only recently been used by the proteomics community to investigate clinical questions such as biomarker verification and validation. Targeted MS holds the promise of a paradigm shift in the quantitative determination of proteins. Nevertheless, targeted quantitative proteomics requires improvisation in making sample processing, instruments, and data analysis more accessible. In the backdrop of the genomic era reaching its zenith, certain questions arise: is the (...)
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  23.  17
    Targeting and tailoring an intervention for adolescents who are overweight.K. Riiser, K. Londal, Y. Ommundsen, N. Misvaer & S. Helseth - 2015 - Nursing Ethics 22 (2):237-247.
    There are important ethical issues to be examined before launching any public health intervention, particularly when targeting vulnerable groups. The aim of this article is to identify and discuss ethical concerns that may arise when intervening for health behavior change among adolescents identified as overweight. These concerns originate from an intervention designed to capacitate adolescents to increase self-determined physical activity. Utilizing an ethical framework for prevention of overweight and obesity, we identified three ethical aspects as particularly significant: the attribution (...)
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  24.  17
    Targeting and tailoring an intervention for adolescents who are overweight.Kirsti Riiser, Knut Løndal, Yngvar Ommundsen, Nina Misvær & Sølvi Helseth - 2015 - Nursing Ethics 22 (2):237-247.
    There are important ethical issues to be examined before launching any public health intervention, particularly when targeting vulnerable groups. The aim of this article is to identify and discuss ethical concerns that may arise when intervening for health behavior change among adolescents identified as overweight. These concerns originate from an intervention designed to capacitate adolescents to increase self-determined physical activity. Utilizing an ethical framework for prevention of overweight and obesity, we identified three ethical aspects as particularly significant: the attribution (...)
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  25.  11
    The Targeted “Solution” in the Spotlight: How a Product Focus Influences Collective Action Within and Beyond Cross-Sector Partnerships.Özgü Karakulak & Lea Stadtler - 2022 - Business and Society 61 (3):606-648.
    Based on a comparative case study of six cross-sector partnerships (CSPs) in global health, we illustrate how a CSP’s aim to address a social issue on the basis of products influences the governance of collective action within the partnership and beyond, at the field level. We show how such product focus, through specialization, influences a CSP’s structures and interaction culture and, as a reflection of the partners’ underlying logics, generates different CSP-field effects. Specifically, if conceived as self-contained and without considering (...)
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  26.  78
    What is a Target System?Alkistis Elliott-Graves - 2020 - Biology and Philosophy 35 (2):1-22.
    Many phenomena in the natural world are complex, so scientists study them through simplified and idealised models. Philosophers of science have sought to explain how these models relate to the world. On most accounts, models do not represent the world directly, but through target systems. However, our knowledge of target systems is incomplete. First, what is the process by which target systems come about? Second, what types of entity are they? I argue that the basic conception of target systems, on (...)
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  27.  9
    Multifaceted targeted protein degradation systems for different cellular compartments.Cornelia E. Zorca, Armaan Fallahi, Sophie Luo & Mohamed A. Eldeeb - 2022 - Bioessays 44 (6):2200008.
    Selective protein degradation maintains cellular homeostasis, but this process is disrupted in many diseases. Targeted protein degradation (TPD) approaches, built upon existing cellular mechanisms, are promising methods for therapeutically regulating protein levels. Here, we review the diverse palette of tools that are now available for doing so throughout the gene expression pathway and in specific cellular compartments. These include methods for directly removing targeted proteins via the ubiquitin proteasome system with proteolysis targeting chimeras (PROTACs) or dephosphorylation targeting chimeras (...)
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  28.  13
    Drones, Targeted Killings and the Politics of Law. Werner - 2015 - Netherlands Journal of Legal Philosophy 44 (2):95-99.
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  29. The proportionality of unilateral 'targeted' sanctions whose interests should count?Alexandra Hofer - 2021 - In Ulf Linderfalk & Eduardo Gill-Pedro (eds.), Revisiting proportionality in international and European law: interests and interest- holders. Leiden, The Netherlands: Koninklijke Brill NV.
     
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  30. Model time and target years : on the end of time in IPCC futures.Nina Wormbs - 2022 - In Anders Ekström & Staffan Bergwik (eds.), Times of history, times of nature: temporalization and the limits of modern knowledge. New York: Berghahn.
     
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  31. Model time and target years : on the end of time in IPCC futures.Nina Wormbs - 2022 - In Anders Ekström & Staffan Bergwik (eds.), Times of history, times of nature: temporalization and the limits of modern knowledge. New York: Berghahn.
     
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  32.  66
    Target Rules for Public Choice Economies on Tree Networks and in Euclidean Spaces.Bettina Klaus - 2001 - Theory and Decision 51 (1):13-29.
    We consider the problem of choosing the location of a public facility either (a) on a tree network or (b) in a Euclidean space. (a) (1996) characterize the class of target rules on a tree network by Pareto efficiency and population-monotonicity. Using Vohra's (1999) characterization of rules that satisfy Pareto efficiency and replacement-domination, we give a short proof of the previous characterization and show that it also holds on the domain of symmetric preferences. (b) The result obtained for model (a) (...)
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  33.  38
    Targeting cancer's weaknesses (not its strengths): Therapeutic strategies suggested by the atavistic model.Charles H. Lineweaver, Paul C. W. Davies & Mark D. Vincent - 2014 - Bioessays 36 (9):827-835.
    In the atavistic model of cancer progression, tumor cell dedifferentiation is interpreted as a reversion to phylogenetically earlier capabilities. The more recently evolved capabilities are compromised first during cancer progression. This suggests a therapeutic strategy for targeting cancer: design challenges to cancer that can only be met by the recently evolved capabilities no longer functional in cancer cells. We describe several examples of this target‐the‐weakness strategy. Our most detailed example involves the immune system. The absence of adaptive immunity in (...)
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  34.  87
    Off-target responses to occasion-sensitivity.Alex Davies - 2014 - Dialectica 68 (4):499-523.
    In the literature on linguistic context-sensitivity, a recurrent move has been made with the intention of attacking Charles Travis's occasion-sensitivity. The move is to provide a semantic analysis of the meaning of an expression which makes the content of that expression context sensitive but without providing any reason to think that the meaning of the expression is a character. I argue that this move is off-target. Such proposals are entirely consistent with occasion-sensitivity and so don't constitute an attack on it.
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  35.  19
    Targeted Killing and the Criminal Law.Alec Walen - 2019 - In Larry Alexander & Kimberly Kessler Ferzan (eds.), The Palgrave Handbook of Applied Ethics and the Criminal Law. Springer Verlag. pp. 753-771.
    The moral justification for targeted killing turns on it being justified as an act of self-defense. That justification can be assessed by addressing five questions: Is the targeted person a threat who lacks the right to threaten? Has the targeted person forfeited some of her claim not to be killed? Even if the answer to the first two questions is positive, is targeted killing a necessary and proportionate response? Is the evidence in favor of targeted killing high enough to meet (...)
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  36.  10
    Nuclear targeting by growth factors, cytokines, and their receptors: a role in signaling?Torunn Elisabeth Tjelle, Torunn Løvdal & Trond Berg - 1998 - Bioessays 20 (5):400-411.
    The role of membrane receptors is regarded as being to transduce the signal represented by ligand binding from the external cell surface across the membrane into the cell. Signals are subsequently conveyed from the cytoplasm to the nucleus through a combination of second-messenger molecules, kinase/phosphorylation cascades, and transcription factor (TF) translocation to effect changes in gene expression. Mounting evidence suggests that through direct targeting to the nucleus, polypeptide ligands and their receptors may have an important additional signaling role. Ligands (...)
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  37.  65
    Targeted Killing.Daniel Statman - 2004 - Theoretical Inquiries in Law 5 (1):179-198.
    The purpose of this paper is to provide a philosophical defense for targeted killings in the wars against terror. The paper argues that if one accepts the moral legitimacy of the large-scale killing of combatants in conventional wars, one cannot object - on moral grounds - to the targeted killing of terrorists in wars against terror. If one rejects this legitimacy, one must object to all killing in war, targeted and non-targeted alike, and thus not support the view, which is (...)
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  38.  11
    Targeting of widening participation measures by elite institutions: widening access or simply aiding recruitment?Jon Rainford - 2017 - Perspectives: Policy and Practice in Higher Education 21 (2-3):45-50.
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  39.  22
    Targeting Procrastination Using Psychological Treatments: A Systematic Review and Meta-Analysis.Alexander Rozental, Sophie Bennett, David Forsström, David D. Ebert, Roz Shafran, Gerhard Andersson & Per Carlbring - 2018 - Frontiers in Psychology 9.
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  40.  13
    'Target Approval Delays Cost Air Force Key Hits': Law, Policy, Ethics and the Warfighter's Dilemma.Michael N. Schmitt - 2002 - Journal of Military Ethics 1 (2):113-124.
    (2002). 'Target Approval Delays Cost Air Force Key Hits': Law, Policy, Ethics and the Warfighter's Dilemma. Journal of Military Ethics: Vol. 1, No. 2, pp. 113-124.
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  41.  26
    Target energy effects on Type 1 and Type 2 visual persistence.Geral M. Long & Paul R. McCarthy - 1982 - Bulletin of the Psychonomic Society 19 (4):219-221.
  42.  5
    Research With Identifiable and Targeted Communities.Morris W. Foster - 2008 - In Ezekiel J. Emanuel (ed.), The Oxford textbook of clinical research ethics. New York: Oxford University Press. pp. 6--475.
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  43.  9
    Targeted Hypermutation as a Survival Strategy: A Theoretical Approach.Seymour Garte - 2023 - Acta Biotheoretica 71 (4).
    Targeted hypermutation has proven to be a useful survival strategy for bacteria under severe stress and is also used by multicellular organisms in specific instances such as the mammalian immune system. This might appear surprising, given the generally observed deleterious effects of poor replication fidelity/high mutation rate. A previous theoretical model designed to explore the role of replication fidelity in the origin of life was applied to a simulated hypermutation scenario. The results confirmed that the same model is useful for (...)
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  44. Targeted Killing.Gerald Lang - 2022 - In Hugh LaFollette (ed.), International Encyclopedia of Ethics. Wiley.
    Targeted killing is a subspecies of assassination, deployed against irregular combatants such as terrorists. The justification for targeted killing bypasses the usual ‘war paradigm’ and ‘criminal enforcement paradigm’, and is thus unusual. There are various ways of securing such a justification, but also a number of dangers attending these arguments.
     
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  45.  24
    Targeting tumor suppressor genes for cancer therapy.Yunhua Liu, Xiaoxiao Hu, Cecil Han, Liana Wang, Xinna Zhang, Xiaoming He & Xiongbin Lu - 2015 - Bioessays 37 (12):1277-1286.
    Cancer drugs are broadly classified into two categories: cytotoxic chemotherapies and targeted therapies that specifically modulate the activity of one or more proteins involved in cancer. Major advances have been achieved in targeted cancer therapies in the past few decades, which is ascribed to the increasing understanding of molecular mechanisms for cancer initiation and progression. Consequently, monoclonal antibodies and small molecules have been developed to interfere with a specific molecular oncogenic target. Targeting gain‐of‐function mutations, in general, has been productive. (...)
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  46.  34
    Target meta-awareness is a necessary condition for physiological responses to masked emotional faces: Evidence from combined skin conductance and heart rate assessment.Myron Tsikandilakis, Peter Chapman & Jonathan Peirce - 2018 - Consciousness and Cognition 58:75-89.
  47.  41
    Target visibility and visual awareness modulate amygdala responses to fearful faces.Luiz Pessoa, Shruti Japee, David Sturman & Leslie G. Ungerleider - 2006 - Cerebral Cortex 16 (3):366-375.
  48.  16
    Target Practice: Counterterrorism and the Amplification of Data Friction.Jon R. Lindsay - 2017 - Science, Technology, and Human Values 42 (6):1061-1099.
    The nineteenth-century strategist Carl von Clausewitz describes “fog” and “friction” as fundamental features of war. Military leverage of sophisticated information technology in the twenty-first century has improved some tactical operations but has not lifted the fog of war, in part, because the means for reducing uncertainty create new forms of it. Drawing on active duty experience with an American special operations task force in Western Iraq from 2007 to 2008, this article traces the targeting processes used to “find, fix, (...)
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  49.  22
    Targeting Terror.Tamar Meisels - 2004 - Social Theory and Practice 30 (3):297-326.
  50.  48
    Targets of discrimination: Effects of race on responses to weapons holders.Anthony Greenwald - manuscript
    Rapid actions to persons holding weapons were simulated using desktop virtual reality. Subjects responded to simulated (a) criminals, by pointing the computerÕs mouse at them and left-clicking (simulated shooting), (b) fellow police officers, by pressing the spacebar (safety signal), and (c) citizens, by inaction. In one of two tasks Black males holding guns were police officers while White males holding guns were criminals. In the other, Whites with guns were police and Blacks with guns were criminals. In both tasks Blacks (...)
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