This article proposes a methodological schema for engaging in a productive discussion of ethical issues regarding human brain organoids, which are three-dimensional cortical neural tissues created using human pluripotent stem cells. Although moral consideration of HBOs significantly involves the possibility that they have consciousness, there is no widely accepted procedure to determine whether HBOs are conscious. Given that this is the case, it has been argued that we should adopt a precautionary principle about consciousness according to which, if we are (...) not certain whether HBOs have consciousness—and where treating HBOs as not having consciousness may cause harm to them—we should proceed as if they do have consciousness. This article emphasizes a methodological advantage of adopting the precautionary principle: it enables us to sidestep the question of whether HBOs have consciousness and, instead, directly address the question of what kinds of conscious experiences HBOs can have, where the what-kind-question is more tractable than the whether-question. By addressing the what-kind-question, we will be able to examine how much moral consideration HBOs deserve. With this in mind, this article confronts the what-kind-question with the assistance of experimental studies of consciousness and suggests an ethical framework which supports restricting the creation and use of HBOs in bioscience. (shrink)

This paper aims to uncover where the disagreement between illusionism and anti-illusionism about phenomenal consciousness lies fundamentally. While illusionists claim that phenomenal consciousness does not exist, many philosophers of mind regard illusionism as ridiculous, stating that the existence of phenomenal consciousness cannot be reasonably doubted. The question is, why does such a radical disagreement occur? To address this question, I list various characterisations of the term “phenomenal consciousness”: (1) the what-it-is-like locution, (2) inner ostension, (3) thought experiments such as philosophical (...) zombies, inverted qualia and Mary’s room, (4) scientific knowledge about secondary properties, (5) theoretical properties such as being ineffable and being intrinsic, and (6) appearance/reality collapse. Then I examine whether each characterization provides (i) a dubitable sense of phenomenal consciousness in which the existence of phenomenal consciousness can be reasonably doubted, (ii) an indubitable sense in which its existence cannot be reasonably doubted, or (iii) a gray sense in which it is controversial whether its existence can be reasonably doubted. By doing so, I show that there is no single sense of phenomenal consciousness in which illusionists and anti-illusionists disagree whether the existence of phenomenal consciousness can be reasonably doubted. I conclude that the disagreement between illusionists and anti-illusionists is fundamentally terminological: while illusionists adopt a dubitable sense of phenomenal consciousness, anti-illusionists adopt an indubitable sense of phenomenal consciousness. Because of the extreme vagueness and ambiguity of the term “phenomenal consciousness”, illusionists and anti-illusionists fail to see that they talk about different senses of phenomenal consciousness. (shrink)

Nobody claims to be a proponent of white feminism, but according to the critique presented in this article, many in fact are. I argue that feminism that does not take multiple axes of oppression into account is bad in three ways: it strategically undermines solidarity between women; it risks inconsistency by advocating justice and equality for some women but not all; and it impedes the ultimate function of feminism function by employing epistemological “master’s tools” that stand in antithesis to feminist (...) emancipatory work. In investigating ethnocentrism in feminism, I develop the idea of latent ethnocentrism, which occupies the space between meaning that is generated from reference to the self and overt racism. I identify an epistemological prong in the ethnocentrism charge against feminism, where I draw on bell hooks’ interlocking axes-model of oppression to answer why the ethnocentrism problem is important for feminism and what its underlying epistemological causes are. I draw on Uma Narayan’s destabilization of cultural dualisms to argue that they do not serve emancipatory agendas. There is a mutually constitutive relation between language that informs our understanding, on the one hand, and the political agendas that produce this language to sustain the male and the western norm as center, on the other hand. I call this circular and reciprocally reinforcing mechanism the episteme-politic. I conclude that the ethnocentrism problem is not merely an issue of strategy or feminist consistency but of shooting oneself in the foot by uncritically accepting patriarchal concepts for feminist politics. (shrink)

The empirical basis for self-control in Dohsa-hou as it relates to effects on cognitive processes has been explored in a few studies of the Japanese psychotherapy, but not under standardized conditions with a strong predictive theory of control. This study reports on a series of experiments with the Dual Mechanisms of Control framework to clarify the possible regulatory mechanism of Dohsa-hou by focusing on shoulder movement, a key body movement task used by practitioners across applied settings. Cognitive control was operationalized (...) with the AX version of Continuous Performance Test paradigm for proactive control and a modified Stroop task paradigm for reactive control in a 3-arm parallel group trial study design. Healthy Japanese university students were assigned to a Dohsa-hou group that performed a shoulder movement task for few minutes, an active control group that performed a similar task, or a passive control group comprised of a resting condition. A total of 55 participants performed the AX-CPT and 57 participants performed the modified Stroop task before and after the group manipulation. In the AX-CPT, an increase in the error rate of AY trial from pre- to post-test was observed in the passive control group only, and found to be marginally higher in the passive control group relative to Dohsa-hou group at post-test. This indicated that Dohsa-hou moderated the activation of proactive control by repeated AX-CPT performance. The error rate of the Proactive Behavioral Index did not differ from zero at post-test only in the Dohsa-hou group, indicating flexible cognitive control. In the modified Stroop task, there was no difference between congruent and incongruent trials at post-test for the Dohsa-hou group only, indicating the facilitation of reactive control. The evidence for a balancing effect for the Dohsa-hou-based shoulder movement task indicates that clients experience a form of continuous self-monitoring, which might reduce mind-wandering from their focus on movement execution combined with iterative verbal feedback from the therapist. Overall, the results of the present study suggest that the self-regulatory mechanism promoted in clinical Dohsa-hou emphasizes guided shifts in attention to the reactive mode toward a balance of cognitive control. (shrink)

In this paper, we investigate processes involving iterative information updating due to van Benthem (Int Game Theory Rev 9: 13—45, 2007), who characterized existent game-theoretic solution concepts by such processes in the framework of Plaza's public announcement logic. We refine this approach and clarify the relationship between stable strategies and information update processes. After extending Plaza's logic, we then derive the conditions under which a stable outcome is determined independently of the order of the iterative information updates. This result gives (...) an epistemic foundation for the order independence of iterated elimination of disadvantageous strategies. (shrink)

Since the collapse of the bubble economy at the beginning of the 1990s, Japan has been in secular stagnation. Despite the stagnant economic conditions, the rate of profit has been rising, not falling. The coexistence of the rise in profitability and prolonged economic stagnation is a manifestation of the fundamental contradiction of present-day Japanese capitalism. Marx’s law of the tendency of the rate of profit to fall provides a consistent explanation regarding the paradoxical situation in Japan characterised not by a (...) falling but a rising rate of profit. Meanwhile, this paper discusses the Monopoly Capitalism school, which has studied capitalist behaviour concerning productive investment and changes in the form of capitalist competition at the monopoly stage of capitalism. While the school’s negation of the LTRPF is unacceptable, their notions may provide useful explanations as to why the rate of profit has risen under secular stagnation in Japan. (shrink)

This paper examines prospects for and content of a global regime for human rights. Competing schools of thought forecast convergence and divergence of national standards under stress of globalization. No such regime exists, and there is no compelling theory of international corporate social responsibility. However, elements of an emerging global regime can be identified and partially overlap with environmental protection issues. This regime is highly fragmented, underdeveloped, and only partially enforceable—but it is in development. The UN Global Compact, the Global (...) Reporting Initiative (GRI), ISO 26000 (expected in 2010), the U.S. Alien Tort Claims Act (ATCA) of 1789 and the permanent international criminal court established in 2002 are illustrations of such elements. The third Ruggie Report, issued 2008, is an important summary of conditions and proposes a strategy for forward progress. Human rights impose important obligations on multinational enterprises (MNEs) operating across highly diverse political, legal, and cultural realities. (shrink)

Epistemological investigation belonged to the core topics in Indian philosophical traditions, too. Right cognition had generally been regarded as one of the important means to emancipation (niḥśreyasa) since ancient times. To reach this religious goal, they keenly discussed the problems of what kinds of cognition we should accept as right or what kinds of objects a right cognition refers to. Specifically it is about the number and the nature of the means of right cognition that opinions differ from school to (...) school. The number ranges from one (perception) to six or even ten (perception, inference, comparison, testimony, implication, non-perception, equivalence, tradition, gesture, and intuition). The concept of each means of right cognition, too, varies greatly among schools. In this paper I take up the Nyāya System, a rationalistic school of Brahmanic philosophy. In Nyāya the inference is regarded as particularly important, but it never means that logical thinking dominates testimony or the authority of religious scriptures in the Nyāya System. On the contrary we find such cases as the religious authority seems to delimit the validity of inference. Some inferences are obstructed by an axiom established in the school, whereas others by a ristriction of Brahmanic tradition. In this manner they seemed to protect their whole system from followers of other Schools. By examining this topic I would like to throw a tiny light on the characteristic affinity between philosophy and religion in Indian thought. (shrink)

This paper proposes a classificatory framework for disjunctivism about the phenomenology of visual perceptual experience. Disjunctivism of this sort is typically divided into positive and negative disjunctivism. This distinction successfully reflects the disagreement amongst disjunctivists regarding the explanatory status of the introspective indiscriminability of veridical perception and hallucination. However, it is unsatisfactory in two respects. First, it cannot accommodate eliminativism about the phenomenology of hallucination. Second, the class of positive disjunctivism is too coarse-grained to provide an informative overview of the (...) current dialectical landscape. Given this, I propose a classificatory framework which preserves the positive-negative distinction, but which also includes the distinction between eliminativism and non-eliminativism, as well as a distinction between two subclasses of positive disjunctivism. In describing each class in detail, I specify who takes up each position in the existing literature, and demonstrate that this classificatory framework can disambiguate some existing disjunctivist views. (shrink)

The aggregation of individual judgments on logically connected issues often leads to collective inconsistency. This study examines two collective decision-making procedures designed to avoid such inconsistency—one premise-based and the other conclusion-based. While the relative desirability of the two procedures has been studied extensively from a theoretical perspective, the preference of individuals regarding the two procedures has been less studied empirically. In the present study, a scenario-based questionnaire survey of participant preferences for the two procedures was conducted, taking into consideration prevailing (...) social norms in the society to which the participants belong and the heterogeneity of the participants’ past experiences. Results show that a minority opinion not matching a prevailing social norm is more likely to be supported when the conclusion-based procedure is used. This can be explained by a basic property of the conclusion-based procedure: The procedure does not require voters to reveal their reasons for reaching a particular conclusion. This property proves appealing for participants who have a minority opinion. Such a finding is highly relevant to future studies on strategic behaviors in choosing a collective decision-making procedure. (shrink)

As kendo continues to gain in international popularity, there are hopes for its adoption in the Olympic Games as an international competitive event, even while moves to further this aim have not necessarily occurred in Japan or elsewhere. One reason for the efforts to achieve a form of globalization of kendo different from Judo is the attempt to adhere to and preserve the unique concepts kendo, the sport embodies by remaining true to the forms of traditional Japanese culture. This is (...) epitomized by the importance given to zanshin (the combination of posture and fighting spirit after striking), one of the key concepts that constitute yuko-datotsu in kendo. Our purpose in this study is to discuss the intersubjective nature of the decisions regarding the conditions for point-scoring in competitive sports. In particular, we will focus on the aesthetics required for zanshin in kendo, focusing on the theory behind yuko-datotsu (point score), which will also considerably influence its international dissemination. Kendo is characterized from the perspective of western rationalism as an appreciation of form and rules of behavior referred to as formalism and, in this respect, it has unique characteristics differing from those of modern sports that are disseminated internationally. In martial arts, besides refinement and proficiency in the rules of behavior by rigidly adhering to form and rules of behavior and repetition, the aim is to transcend said form and the rules of behavior and embody the spiritual nature dwelling in the background. Kendo should remain traditional path and keep zanshin in the value of point (yuko-datotsu) for its virtue. Kendo has not yet developed into an international competitive sport, but it is in the process of traversing that Geido path as a Do for the purpose of character building through it. Throughout life, one should try to devote oneself to kendo with thought for the value of transcending form and the rules of behaviour, and embodying the spiritual nature of the sport that inheres in its background. That is why one may perceive an evident hesitation or indeed negativity regarding the possible internationalization or development as an Olympic event. (shrink)

Robustness is a fundamental property of biological systems, observed ubiquitously across species and at different levels of organization from gene regulation to ecosystem. The theory of biological robustness argues that robustness fosters evolv-ability and that together they entail various tradeoffs as well as characteristic architectures and mechanisms. We argue that classes of biological systems have evolved to enhance their robustness by extending their system boundary through a series of symbioses with foreign biological entities . A series of major biological innovations (...) has been achieved by events consistent with this framework: horizontal gene transfer, serial endosymbiosis, oocytes-mediated vertical infection, and host-symbiont mutualism for bacterial flora. Self-extending symbiosis contributes to robustness because symbiotic foreign biological entities can enhance the adaptative capacity of the system against environmental perturbations as well as contribute novel functions. In addition, evolutionary history indicates that the degree of symbiosis achieved has substantially changed from tight integration into the genome to loose integration as bacterial flora . The most dramatic example can be seen in the symbiosis of host immune system and bacterial flora in which substantial function of host defense depends on the proper maintenance of bacterial flora and its adaptive capability. Biological systems following this type of evolutionary path might have attained high levels of functionality, robustness, and evolvability. Thus, robustness, evolution, and self-extending symbiosis may form essential system principles for biology. (shrink)

ABSTRACTHobbes's unusual religious views in his classical work, Leviathan, are often seen as a product of his attempt to reconcile Christianity with his philosophical materialism. Yet given Hobbes's materialistic view in his earlier works too, this explanatory framework alone is not sufficient for grasping distinctive features of Leviathan. This article remedies this lacuna by paying close attention to an understudied aspect of the development of Hobbes's religious theory from The Elements of Law to Leviathan: his treatment of the supernatural and, (...) particularly, of matters of faith known by supernatural revelation as opposed to natural reason. I argue that over time Hobbes developed an epistemological analysis of supernatural revelation and refined his argument about the sense in which matters of faith are supernatural and about the extent to which they are found in the Bible. It was not materialism per se but the more sophisticated analysis of the supernatural in Leviathan that enabled Hobbes to admit the sphere of the supernatural to a much smaller extent than in De Cive and to discuss in detail what he sees as a matter of faith and beyond the scope of philosophy in De Cive. (shrink)

Smithies defends the phenomenal sufficiency thesis, according to which every perceptual experience provides immediate, defeasible justification to believe some content in virtue of its phenomenal character alone. This commentary challenges this thesis by presenting two kinds of knowledge, the possession of which seems necessary for perceptual justification.

IntroductionPrevious transcranial magnetic stimulation studies have revealed that the activity of the primary motor cortex ipsilateral to an active hand plays an important role in motor control. The aim of this study was to investigate whether the ipsi-M1 excitability would be influenced by goal-directed movement and laterality during unilateral finger movements.MethodTen healthy right-handed subjects performed four finger tapping tasks with the index finger: simple tapping task, Real-word task, Pseudoword task, and Visually guided tapping task. In the Tap task, the subject (...) performed self-paced simple tapping on a touch screen. In the real-word task, the subject tapped letters displayed on the screen one by one to create a Real-word. Because the action had a specific purpose, this task was considered to be goal-directed as compared to the Tap task. In the Pseudoword task, the subject tapped the letters to create a pseudoword in the same manner as in the Real-word task; however, the word was less meaningful. In the VT task, the subject was required to touch a series of illuminated buttons. This task was considered to be less goal-directed than the Pseudoword task. The tasks were performed with the right and left hand, and a rest condition was added as control. Single- and paired-pulse TMS were applied to the ipsi-M1 to measure corticospinal excitability and short- and long-interval intracortical inhibition in the resting first dorsal interosseous muscle.ResultsWe found the smaller SICI in the ipsi-M1 during the VT task compared with the resting condition. Further, both SICI and LICI were smaller in the right than in the left M1, regardless of the task conditions.DiscussionWe found that SICI in the ipsi-M1 is smaller during visual illumination-guided finger movement than during the resting condition. Our finding provides basic data for designing a rehabilitation program that modulates the M1 ipsilateral to the moving limb, for example, for post-stroke patients with severe hemiparesis. (shrink)

There are many theories of the functions of consciousness. How these theories relate to each other, how we should assess them, and whether any integration of them is possible are all issues that remain unclear. To contribute to a solution, this paper offers a conceptual framework to clarify the theories of the functions of consciousness. This framework consists of three dimensions: (i) target, (ii) explanatory order, and (iii) necessity/sufficiency. The first dimension, target, clarifies each theory in terms of the kind (...) of consciousness it targets. The second dimension, explanatory order, clarifies each theory in terms of how it conceives of the explanatory relation between consciousness and function. The third dimension, necessity/sufficiency, clarifies each theory in terms of the necessity/sufficiency relation posited between consciousness and function. We demonstrate the usefulness of this framework by applying it to some existing scientific and philosophical theories of the functions of consciousness. (shrink)

Lonely hearts advertisements (LHA) published in Japan were examined in a comparative study on sexually dimorphic mate preference. I analyzed 944 LHA written by Japanese (730 by males and 214 by females) seeking short-term relationships and 780 LHA (577 by males and 203 by females) seeking long-term relationships. Some universal patterns of mate preference were confirmed and others were not. Female advertisers in both categories sought more traits than they offered; they also sought more traits than male advertisers. Males tended (...) to offer their financial and social status, and females tended to seek those traits. More females requested family commitment than males. While there was no sex difference in offering and seeking physical appearance and health, females tended to request photographs of their potential mates. Males were more likely than females to be willing to accept children from previous relationships, although there was no significant difference in refusing such children. More females seeking long-term mates requested family commitment than females seeking short-term mates. In both males and females, more advertisers seeking long-term mates offered family commitment than advertisers seeking short-term mates. Some predictions for contingent preference were also examined. One prediction confirmed was that females offering physical appearance and health sought more traits than those not doing so. However, males offering financial and social status did not make higher demands than those who did not, which does not support one prediction. (shrink)