The neuromodulatory effects of brain stimulation therapies notably involving repetitive transcranial magnetic stimulation on nocturnal sleep, which is critically disturbed in major depression and other neuropsychiatric disorders, remain largely undetermined. We have previously reported in major depression patients that prefrontal rTMS sessions enhanced their slow wave activity power, but not their sigma power which is related to sleep spindle activity, for electrodes located nearby the stimulation site. In the present study, we focused on measuring the spindle density to investigate cumulative (...) effects of prefrontal rTMS sessions on the sleep spindle activity. Fourteen male inpatients diagnosed with medication-resistant unipolar or bipolar depression were recruited and subjected to 10 daily rTMS sessions targeting the left dorsolateral prefrontal cortex. All-night polysomnography data was acquired at four time points: Adaptation, Baseline, Post-1, and Post-2. Clinical and cognitive evaluations were longitudinally performed at Baseline, Post-1, and Post-2 time points to explore associations with the spindle density changes. The PSG data from 12 of 14 patients was analyzed to identify sleep spindles across the sleep stages II–IV at four electrode sites: F3, F4, P3, and P4. Statistical analysis by two-way ANOVA revealed that spindle density at F3 increased at Post-1 but decreased at Post-2 time points. Moreover, the local and transient increase of spindle density at F3 was associated with the previously reported SWA power increase at F3, possibly reflecting a shared mechanism of thalamocortical synchronization locally enhanced by diurnal prefrontal rTMS sessions. Clinical and cognitive correlations were not observed in this dataset. These findings suggest that diurnal rTMS sessions transiently modulate nocturnal sleep spindle activity at the stimulation site, although clinical and cognitive effects of the local changes warrant further investigation. (shrink)

明治大学文学部は、2018年4月に哲学専攻を新設した。いま、なぜ、哲学なのか?アジアにとって、哲学とは何か?理論とプラクティスが、西洋と東洋がクロスする新しい場から5名の創設メンバーが贈る“知”のスタ ーティングガイド。.

dai 1-kan. Kōshitsu hen. Kokka shakai hen. Gunji hen. Shisō hen. Kyōkun hen. Shūkyō hen -- dai 2-kan. Gakugei hen. Keizai sangyō hen. Shūyō hen. Ningen hen -- dai 3-kan. Undō kyōgi shumi hen. Katei hen. Daihyō ijin jūninin kun.

日本人は「死」にどう向き合うべきなのか。西洋との違い、仏教の影響、私たちの古層にある死生観―社会思想の大家による渾身の論考.

The paper attempts to construct a global model of a social contract using well-known metaphors of two great philosophers: Jean-Jacques Rousseau and John Locke. By modelling a global social contract, I mean the formulation of a social contract using two sets of data: one is global citizens' preferences about values and norms while the other is sovereign states' participation in multilateral treaties. Both Rousseau and Locke formulate their versions of social contract theories in the national context of eighteenth-century Europe. This (...) paper tries my hands on extending their theories to the global context. This paper attempts to link empirically the relationship between global citizens' preferences as gauged by the World Values Survey and sovereign states' participation in 120 multilateral treaties deposited to the United Nations. To see the link between citizens and treaties (quasi-legislative outcomes, sort of), dimensional similarities of the cosmos of citizens' preference and the cosmos of sovereign states' willingness to join multilateral treaties are examined. Once done, all the sovereign states are located in each of the two cosmoses, citizens and states, and the correlation coefficients between them are measured. Based on these empirical results, the nature of the global quasi-legislative process is clarified. Conclusions and implications are drawn. (shrink)

林家は、朱子学者・林羅山を始祖とする江戸幕府に仕えた儒官の家柄である。大坂冬の陣の発端となった方広寺鐘銘事件から、史書『本朝通鑑』の編纂、湯島聖堂の創建、大学頭叙任、赤穂浪士討ち入り事件への対応、そし て新井白石との対立まで―。初代羅山・二代鵞峰・三代鳳岡は、歴代将軍の寵用と冷遇に翻弄されながらも、江戸期朱子学の確立に奔走した。その林家三代一五〇年の闘いと事績を描く。.

Was konnen Rechtsvergleich und Rechtsgeschichte leisten? Der Autor beantwortet diese Frage mit Blick auf die Gesetzgebungslehre des deutschen Juristen und Philosophen Christian Thomasius (1655-1728). Er weist nach, dass dessen Gesetzgebungslehre sich im Bereich des Privatrechts grundsatzlich durchsetzte und auf die Gesetzgebung der fruhen Neuzeit grossen Einfluss hatte, obwohl Thomasius kein originales Gesetzbuch verfasste. Der Jurist war der Meinung, man konne durch Rechtsvergleich vermuten, dass eine heimische Sitte, die den gemeinsamen Sitten vieler Volker bzw. dem Volkergemeinrecht entspreche, geeignet sei, ins Gesetzbuch (...) aufgenommen zu werden. Er stutzte diesen Vergleich durch historische Betrachtungen.". (shrink)

江戸時代の儒学者・宗教者である山崎闇斎の思想を、心理学・文化人類学・現代哲学等を取り入れた学際的なアプローチで解明する。.

闇斎門下の個性豊かな諸家の事跡を通して、垂加神道の史的展開を検討すると共に、『日本書紀』神代巻の解釈に見える思想の根幹を明らかにする。.

予備知識不要(多少の忍耐力は必要)。わたしたちの日常を支えるもっとも基礎的な概念「正しい」を、理屈にこだわり丁寧に分析する哲学入門。.

This article contributes to the critical engagement with luck egalitarianism by advancing two arguments. Firstly, it questions the cogency of the dichotomies – e.g., luck/choice, person/circumstance, agency/structure – and the accompanying moral ideal of pure voluntarism. This makes it difficult for luck egalitarianism to dissect appropriately the inequalities embedded in social relations, such as social networks and involuntary associations, in which voluntariness and contingency as well as agency and structure are intertwined. Secondly, it suggests that the relational approach, which has (...) been developed, inter alia, in the empirical study of inequality, provides a morally and practically adequate perspective on egalitarian justice. The relational approach achieves this by converging upon those in‐between social relations that are irreducible to the macro‐level structure and to micro‐level agency. Moreover, a relationally sensitive perspective on inequality can adeptly respond to the difficulties that luck‐egalitarian theories encounter. (shrink)

ABSTRACTAnother individual’s gaze automatically shifts an observer’s attention to a location. This reflexive response occurs even when the gaze is presented subliminally over a short period. Another’s gaze also increases the preference level for items in the gaze direction; however, it was previously unclear if this effect occurs when the gaze is presented subliminally. This study showed that the preference levels for nonsense figures looked at by a subliminal gaze were significantly greater than those for items that were subliminally looked (...) away from. Targets that were looked at by a subliminal gaze were detected faster ; however, the participants were unable to detect the gaze direction. These results indicate that another individual’s gaze automatically increases the preference levels for items in the gaze direction without conscious awareness. (shrink)