Resumen: En la actualidad existe amplia evidencia acerca de la variación alofónica del fonema /tʃ/ en el español de Chile asociada a factores socioculturales; sin embargo, estas investigaciones se han focalizado en la población adulta. Considerando lo anterior, la presente investigación tuvo por objetivo analizar la articulación del fonema /tʃ/ en una muestra de 161 niños/as desde los 2,0 a los 3,11 años de edad residentes de la ciudad de Temuco. La muestra fue dividida según edad y NSE. Entre los (...) principales resultados se observó variabilidad entre los grupos analizados según el cruce de las variables edad y NSE. En cuanto a la variación alofónica del fonema /tʃ/ según el NSE, también se evidenció un comportamiento variable entre los grupos analizados. Los resultados de esta investigación concuerdan con las discusiones actuales respecto de la relación entre los procesos evolutivos propios de la adquisición y la emergencia de variaciones de tipo social.: Currently there is a vast evidence on the allophonic variation of the phoneme /tʃ/ in Chilean Spanish, associated to social factors. Nevertheless, these researches focused on adult population. With this consideration, this study aims to analyze the articulation of the /tʃ/ phoneme in a sample of 161 kids, from 2.0 to 3.11 years old who live the city of Temuco. The sample was divided per age and socioeconomic status. Among the main results, a variably between the groups has been observed, crossing the variables age and socioeconomic status. Concerning the allophonic variable of the /tʃ/ phoneme according to the socioeconomic status, there has also been evidenced a variable behavior between the groups. The results of this study are in concordance with the current discussions on the relationship between evolutionary acquisition processes and the emergence of social variations. (shrink)

T‐bet and Eomes are two related transcription factors (TFs) that regulate the differentiation of cytotoxic lymphocytes such as Natural Killer (NK) cells and CD8 T cells. Recent genome‐wide analyses suggest they have complementary roles in instructing the transcriptional program of NK cells, although their DNA binding sites appear to be very similar. In this essay, we discuss the mechanisms that could specify their action, addressing their expression profile, the cofactors they interact with, as well as their roles in the epigenetic (...) regulation of chromatin accessibility. Based on the recent literature on these TFs, we propose different models to describe how they regulate gene expression in NK cells at steady state, or in the context of activation or exhaustion. We also discuss recent findings in the field of CD8 T cell differentiation and residency, where Eomes and T‐bet appear to be major regulators, and the parallels that can be drawn between mechanisms of NK and CD8 T cell differentiation and trafficking. (shrink)

Some philosophers have thought that life could only be meaningful if there is no God. For Sartre and Nagel, for example, a God of the traditional classical theistic sort would constrain our powers of self-creative autonomy in ways that would severely detract from the meaning of our lives, possibly even evacuate our lives of all meaning. Some philosophers, by contrast, have thought that life could only be meaningful if there is a God. God and the Meanings of Life is interested (...) in exploring the truth in both these schools of thought, seeking to discover what God could and couldn't do to make life meaningful (as well as what he would and wouldn't do). Mawson espouses a version of the 'amalgam' or 'pluralism' thesis about the issue of life's meaning – in essence, that there are a number of different legitimate meanings of 'meaning' (and indeed 'life') in the question of life's meaning. According to Mawson, God, were he to exist, would help make life meaningful in some of these senses and hinder in some others. He argues that whilst there could be meaning in a Godless universe, there could be other sorts of meaning in a Godly one and that these would be deeper. (shrink)

T. A. Cavanaugh's Hippocrates' Oath and Asclepius' Snake: The Birth of the Medical Profession articulates the Oath as establishing the medical profession's unique internal medical ethic - in its most basic and least controvertible form, this ethic mandates that physicians help and not harm the sick. Relying on Greek myth, drama, and medical experience (e.g., homeopathy), the book shows how this medical ethic arose from reflection on the most vexing medical-ethical problem -- injury caused by a physician -- and argues (...) that deliberate iatrogenic harm, especially the harm of a doctor choosing to kill (physician assisted suicide, euthanasia, abortion, and involvement in capital punishment), amounts to an abandonment of medicine as an exclusively therapeutic profession. The book argues that medicine as a profession necessarily involves stating before others what one stands for: the good one seeks and the bad one seeks to avoid on behalf of the sick, and rejects the view that medicine is purely a technique lacking its own unique internal ethic. It concludes noting that medical promising (as found in the White Coat Ceremony through which U. S. medical students matriculate) implicates medical autonomy which in turn merits respect, including honoring professional conscientious objections. (shrink)

How do we think about animals? How do we decide what they deserve and how we ought to treat them? Subhuman takes an interdisciplinary approach to these questions, drawing from research in philosophy, neuroscience, psychology, law, history, sociology, economics, and anthropology. Subhuman argues that our attitudes to nonhuman animals, both positive and negative, largely arise from our need to compare ourselves to them.

Kit Fine (2000) breaks with tradition, arguing that, pace Russell (e.g., 1903: 228), relations have neither directions nor converses. He considers two ways to conceive of these new "neutral" relations, positionalism and anti-positionalism, and argues that the latter should be preferred to the former. Cody Gilmore (2013) argues for a generalization of positionalism, slot theory, the view that a property or relation is n-adic if and only if there are exactly n slots in it, and (very roughly) that each slot (...) may be occupied by at most one entity. Slot theory (and with it, positionalism) bears the full brunt of Fine's (2000) symmetric completions and conflicting adicities problems. I fully develop an alternative, plural slot theory (or pocket theory), which avoids these problems, key elements of which are first considered by Yi (1999: 168 ff.). Like the slot theorist, the pocket theorist posits entities (pockets) in properties and relations that can be occupied. But unlike the slot theorist, the pocket theorist denies that at most one entity can occupy any one of them. As a result, she must also deny that the adicity of a property or relation is equal to the number of occupiable entities in it. By abandoning these theses, however, the pocket theorist is able to avoid Fine's problems, resulting in a stronger theory about the internal structure of properties and relations. Pocket theory also avoids a serious drawback of anti-positionalism. (shrink)

Exegesis, with text, on the Nyāyasūtra of Gautama, basic aphoristic text of Nyāya.

_Purpose._ This paper aims to investigate the phenomenon of a human being within the Confucian tradition as well as its interpretations from intercultural perspective. _Theoretical basis._ One of the ways to understand the deepest level of the intercultural dialogue is to reveal the interpretations of a human being in philosophical traditions, since they refer to the formation of personality and identity within a given culture including interpersonal, intergroup, and intercultural relations. Humanism based on the unity of Human and Heaven runs (...) like a red thread through the philosophical teachings of Confucius, Mencius, Xunzi, Zhu Xi, Wang Yangming defining the ideas of human nature, his/her duties, his/her place and roles in society that shaped the Chinese mentality. _Originality._ Quite often, Chinese concepts (for example, human dignity beyond the ideas of democracy and mass political participation, guanxi, mianzi) are incomprehensible to the representatives of the Western civilization, which leads to the challenges in intercultural communication. The interpretation of these ideas in the context of Confucianism allows to understand them from the perspective of Others and expand the set of patterns of cultural perception. This ultimately leads to the awareness that there are many social, political, cultural realities, which we perceive through the lens of our own concepts and attitudes. The participants of an intercultural dialogue realize that each of them has a unique experience, own way of posing a problem and resolving it, and no one is better or worse. _Conclusions._ Confucian philosophy shaped the worldview of Chinese people, defined values, goals, meanings, attitudes, communication models, which affected all spheres of Chinese life and culture. The study of the philosophical heritage of the great Chinese civilization enhances the cultural competence of the intercultural communicators and expands the field of dialogue to the level of global communication. (shrink)

Commentary on Hetvābhāsasāmānyanirukti, portion of Tattvacintāmaṇi of Gaṅgeśa, dealing with the definition of fallacies middle term in Navya Nyāya philosophy.

This robust, clear, and well-researched textbook for classes in logic introduces students to both formal logic and to the virtues of intellectual inquiry. Part 1 challenges students to develop the analytical skills of deductive and inductive reasoning, showing them how to identify and evaluate arguments. Part 2 helps students develop the intellectual virtues of the wise inquirer. The book includes helpful pedagogical features such as practice exercises and a concluding summary with definitions of key concepts for each chapter. Resources for (...) professors and students are available through Baker Academic's Textbook eSources. (shrink)

Knowledge, theory of; Islamic philosophy; philosophy, Arab; interpretation and construction.

Logic; Islamic philosophy; Islam--doctrines.

This book includes critical editions, Turkish translations and short studies of two treatises by Taşköprüzade, one of the most important Ottoman philosophers of the sixteenth century.

This book includes a critical edition and a Turkish translation and a study of an Arabic treatise by Taşköprüzade, one of the most important Ottoman philosophers of the sixteenth century.

Modernism; influence; social and economic aspects; Arab countries; 21st century.

Thinking about Animals in the Age of the Anthropocene makes connections between the Anthropocene discourse and human-animal studies, thus facilitating further interdisciplinary work on the topic of animals in the Anthropocene.

Entry on the Stanford Encyclopedia of Philosophy. A summary of the literature on whether externalism about thought content precludes non-empirical knowledge of one's own thoughts.

From the time of Locke, discussions of personal identity have often ignored the question of our basic metaphysical nature: whether we human people are biological organisms, spatial or temporal parts of organisms, bundles of perceptions, or what have you. The result of this neglect has been centuries of wild proposals and clashing intuitions. What Are We? is the first general study of this important question. It beings by explaining what the question means and how it differs from others, such as (...) questions of personal identity and the mind-body problem. It then examines in some depth the main possible accounts of our metaphysical nature, detailing both their theoretical virtues and the often grave difficulties they face. The book does not endorse any particular account of what we are, but argues that the matter turns on more general issues in the ontology of material things. If composition is universal--if any material things whatever make up something bigger--then we are temporal parts of organisms. If things never compose anything bigger, so that there are only mereological simples, then we too are simples--perhaps the immaterial substances of Descartes--or else we do not exist at all (a view Olson takes very seriously). The intermediate view that some things compose bigger things and others do not leads almost inevitably to the conclusion that we are organisms. So we can discover what we are by working out when composition occurs. (shrink)

Arabic literature; history and criticism.