The invention in 1986 of scanning force microscopy (SFM) provided a new and powerful tool for the investigation of biological structures. SFM yields a three‐dimensional view at nanometer resolution of the surface topography associated with biological objects. The potential for imaging either macromolecules or biomolecules and cells under native (physiological) conditions is currently being exploited to obtain functional information at the molecular level. In addition, the forces involved in individual bimolecular interactions are being assessed under static and dynamic conditions. In (...) this report we focus on the imaging capability of the SFM. The rather broad spectrum of applications represented is intended to orient the prospective user of biological SFM. (shrink)

Nick Bostrom’s “simulation argument” purports to show that if it is possible to create and run a vast number of computer simulations indistinguishable from the reality we are living in, then it is highly probable that we are already living in a computer simulation. However, the simulation argument requires a modification to escape the undermining implications of the scepticism it implies, as argued by Birch. The present paper shows that, even if the modified simulation argument is valid, still it is (...) unsound since it relies on the indistinguishability assumption that even in principle cannot be tested. To account for the unsoundness of the simulation argument, the present paper draws on John Woods' theory of fiction, to expose structural similarities between general fiction and the simulation argument. Though the simulation argument is unsound, it seems persuasive, because the argument immerses the reader in a fictive world with the help of tacit assumptions, leveraging just enough common sense to remain compelling while covering over an untestable premise. Simultaneously with the critique of Bostrom’s argument, Chalmers' argument for the matrix hypothesis is assessed on similar criteria. In either case, both arguments rely on an accumulation of assumptions, both implicit and explicit, hiding the premises that are untestable in principle. (shrink)

Dada continues to attract a small following among scholars, but has perhaps not yet been recognized as providing invaluable insight into the underlying functions and potentials of culture generally. This article explores the nature and theoretical import of Dada, and two radically different visions of culture as they might try to accommodate and explain Dada. Models of culture taken from Bourdieu and Nietzsche are brought to bear, first on Dada, and then on each other, with the aim of developing a (...) theoretically informed understanding of Dada, and also demonstrating the practical, political and philosophical difficulties involved in choosing between a conflict model of culture and an `existential' model. Ultimately, both models are found to be helpful but insufficient at providing an adequate account of Dada, and it is suggested that present models of cultural analysis can benefit by revisiting both Dada and Nietzsche, trying to incorporate their insights and critically evaluate their visions of culture. (shrink)

The present paper intends to show that computer simulations used in science are akin to fiction. Starting from the problem of defining computer simulation, the paper discusses the uses and disadvantages of simulations in science. Computer simulations have a representational function, but they do not resemble the phenomena that they purport to represent. Computer simulations do not preserve the content of the models, input data, and theories from which they proceed, since the content is modified by computational processes. Because of (...) the complexities of these processes, we cannot control or test the methods used to process the content of computer simulations. Still, simulations may help to explain the behaviour of a possible aspect of the phenomenon under examination. Although their role in doing so may be limited, by conforming to and immersing us in the worldview of science, simulations, thus reinforce the intuitions of the existing body of scientific knowledge, and similarly to the “believable fiction” described by John Woods, provide genuine understanding. (shrink)

The contemporary conceptions of universal basic income, tax havens extraction, and climate emergency are briefly presented in the form of exposition in Massive Attack?s Eutopia EP. These conceptions address the most concerning issues of today?s world, while the concept of eutopia, proposed by Massive Attack?s Robert Del Naja and Mark Donne, represents?a place of well-being, as a practical aspiration,? a realistic utopia in which those issues are resolved. The present paper discusses the conceptions presented in Eutopia, assessing the possibility of (...) the materialisation of eutopia. As suggested by Massive Attack, the ideas of Eutopia can be traced back to More?s Utopia, being rooted in a humanistic endeavour of improving humanity, inspiring engagement and search for a better and just society. Apart from discussing Eutopia, the paper explores Another Now, the political science-fiction novel by Yanis Varoufakis. Varoufakis? critique of capitalism and the alternative he proposes in the novel Another Now argue along the same line as Eutopia, encouraging engagement in today?s world. (shrink)

Some philosophers have thought that life could only be meaningful if there is no God. For Sartre and Nagel, for example, a God of the traditional classical theistic sort would constrain our powers of self-creative autonomy in ways that would severely detract from the meaning of our lives, possibly even evacuate our lives of all meaning. Some philosophers, by contrast, have thought that life could only be meaningful if there is a God. God and the Meanings of Life is interested (...) in exploring the truth in both these schools of thought, seeking to discover what God could and couldn't do to make life meaningful (as well as what he would and wouldn't do). Mawson espouses a version of the 'amalgam' or 'pluralism' thesis about the issue of life's meaning – in essence, that there are a number of different legitimate meanings of 'meaning' (and indeed 'life') in the question of life's meaning. According to Mawson, God, were he to exist, would help make life meaningful in some of these senses and hinder in some others. He argues that whilst there could be meaning in a Godless universe, there could be other sorts of meaning in a Godly one and that these would be deeper. (shrink)

The world is awash in bullshit, and we're drowning in it. Politicians are unconstrained by facts. Science is conducted by press release. Startup culture elevates bullshit to high art. These days, calling bullshit is a noble act. Based on Carl Bergstrom and Jevin West's popular course at the University of Washington, Calling Bullshit is a modern handbook to the art of skepticism. Bergstrom, a computational biologist, and West, an information scientist, catalogue bullshit in its many forms, explaining and offering readers (...) the tools to see through the obfuscations, deliberate and careless, that dominate every realm of our lives. They instruct readers to ask: Who is saying it? How do they know? What do they have to gain by persuading me? Are the numbers or results too good or too dramatic to be true? Is the claim comparing like with like or apples and oranges? Is it confirming your personal bias? In this lively guide to everything from misleading statistics to "fake news," Bergstrom and West help you recognize bullshit whenever and wherever you encounter it--in data, in conversation, even within yourself--and explain it to your crystal-loving aunt or casually racist uncle. Now more than ever, calling bullshit is crucial to a properly functioning community, whether it be a circle of friends, a network of academics, or the citizenry of a nation. (shrink)

T. A. Cavanaugh's Hippocrates' Oath and Asclepius' Snake: The Birth of the Medical Profession articulates the Oath as establishing the medical profession's unique internal medical ethic - in its most basic and least controvertible form, this ethic mandates that physicians help and not harm the sick. Relying on Greek myth, drama, and medical experience (e.g., homeopathy), the book shows how this medical ethic arose from reflection on the most vexing medical-ethical problem -- injury caused by a physician -- and argues (...) that deliberate iatrogenic harm, especially the harm of a doctor choosing to kill (physician assisted suicide, euthanasia, abortion, and involvement in capital punishment), amounts to an abandonment of medicine as an exclusively therapeutic profession. The book argues that medicine as a profession necessarily involves stating before others what one stands for: the good one seeks and the bad one seeks to avoid on behalf of the sick, and rejects the view that medicine is purely a technique lacking its own unique internal ethic. It concludes noting that medical promising (as found in the White Coat Ceremony through which U. S. medical students matriculate) implicates medical autonomy which in turn merits respect, including honoring professional conscientious objections. (shrink)

This text is designed to help students construct and evaluate arguments.

Kit Fine (2000) breaks with tradition, arguing that, pace Russell (e.g., 1903: 228), relations have neither directions nor converses. He considers two ways to conceive of these new "neutral" relations, positionalism and anti-positionalism, and argues that the latter should be preferred to the former. Cody Gilmore (2013) argues for a generalization of positionalism, slot theory, the view that a property or relation is n-adic if and only if there are exactly n slots in it, and (very roughly) that each slot (...) may be occupied by at most one entity. Slot theory (and with it, positionalism) bears the full brunt of Fine's (2000) symmetric completions and conflicting adicities problems. I fully develop an alternative, plural slot theory (or pocket theory), which avoids these problems, key elements of which are first considered by Yi (1999: 168 ff.). Like the slot theorist, the pocket theorist posits entities (pockets) in properties and relations that can be occupied. But unlike the slot theorist, the pocket theorist denies that at most one entity can occupy any one of them. As a result, she must also deny that the adicity of a property or relation is equal to the number of occupiable entities in it. By abandoning these theses, however, the pocket theorist is able to avoid Fine's problems, resulting in a stronger theory about the internal structure of properties and relations. Pocket theory also avoids a serious drawback of anti-positionalism. (shrink)

How do we think about animals? How do we decide what they deserve and how we ought to treat them? Subhuman takes an interdisciplinary approach to these questions, drawing from research in philosophy, neuroscience, psychology, law, history, sociology, economics, and anthropology. Subhuman argues that our attitudes to nonhuman animals, both positive and negative, largely arise from our need to compare ourselves to them.

Exegesis, with text, on the Nyāyasūtra of Gautama, basic aphoristic text of Nyāya.

_Purpose._ This paper aims to investigate the phenomenon of a human being within the Confucian tradition as well as its interpretations from intercultural perspective. _Theoretical basis._ One of the ways to understand the deepest level of the intercultural dialogue is to reveal the interpretations of a human being in philosophical traditions, since they refer to the formation of personality and identity within a given culture including interpersonal, intergroup, and intercultural relations. Humanism based on the unity of Human and Heaven runs (...) like a red thread through the philosophical teachings of Confucius, Mencius, Xunzi, Zhu Xi, Wang Yangming defining the ideas of human nature, his/her duties, his/her place and roles in society that shaped the Chinese mentality. _Originality._ Quite often, Chinese concepts (for example, human dignity beyond the ideas of democracy and mass political participation, guanxi, mianzi) are incomprehensible to the representatives of the Western civilization, which leads to the challenges in intercultural communication. The interpretation of these ideas in the context of Confucianism allows to understand them from the perspective of Others and expand the set of patterns of cultural perception. This ultimately leads to the awareness that there are many social, political, cultural realities, which we perceive through the lens of our own concepts and attitudes. The participants of an intercultural dialogue realize that each of them has a unique experience, own way of posing a problem and resolving it, and no one is better or worse. _Conclusions._ Confucian philosophy shaped the worldview of Chinese people, defined values, goals, meanings, attitudes, communication models, which affected all spheres of Chinese life and culture. The study of the philosophical heritage of the great Chinese civilization enhances the cultural competence of the intercultural communicators and expands the field of dialogue to the level of global communication. (shrink)

Commentary on Hetvābhāsasāmānyanirukti, portion of Tattvacintāmaṇi of Gaṅgeśa, dealing with the definition of fallacies middle term in Navya Nyāya philosophy.

This robust, clear, and well-researched textbook for classes in logic introduces students to both formal logic and to the virtues of intellectual inquiry. Part 1 challenges students to develop the analytical skills of deductive and inductive reasoning, showing them how to identify and evaluate arguments. Part 2 helps students develop the intellectual virtues of the wise inquirer. The book includes helpful pedagogical features such as practice exercises and a concluding summary with definitions of key concepts for each chapter. Resources for (...) professors and students are available through Baker Academic's Textbook eSources. (shrink)

Knowledge, theory of; Islamic philosophy; philosophy, Arab; interpretation and construction.

T.J. Reed's study has long established itself as the standard work in English on Thomas mann, and offers as comprehensive a view of Mann's fiction and thought as is available in any language. It is based on a coherent close reading of Mann's oeuvre, literary and political, and also on manuscripts and sources, and was part of the first phase of literary scholarship that opened up the resources of the Zurich Thomas Mann Archive. Further documents that have appeared since then (...) - Mann's diaries, notebooks, and other correspondences - have not fundamentally altered the individual interpretations or the overall picture the study offers, and in some respects have emphatically confirmed them. A further chapter added to this edition covers the new documentation, gives a vigorous account of the main curents in Mann scholarship and criticism over the last two decades suggesting how we should now see the writer, the man, and the political figure, and above all the complex relationship between the three. (shrink)

Logic; Islamic philosophy; Islam--doctrines.

This book includes critical editions, Turkish translations and short studies of two treatises by Taşköprüzade, one of the most important Ottoman philosophers of the sixteenth century.

This book includes a critical edition and a Turkish translation and a study of an Arabic treatise by Taşköprüzade, one of the most important Ottoman philosophers of the sixteenth century.

Modernism; influence; social and economic aspects; Arab countries; 21st century.