Recent interest in the external validity of prediction models has produced many methods for finding predictive distributions that are invariant to dataset shifts and can be used for prediction in new, unseen environments. However, these methods consider different types of shifts and have been developed under disparate frameworks, making it difficult to theoretically analyze how solutions differ with respect to stability and accuracy. Taking a causal graphical view, we use a flexible graphical representation to express various types of dataset shifts. (...) Given a known graph of the data generating process, we show that all invariant distributions correspond to a causal hierarchy of graphical operators, which disable the edges in the graph that are responsible for the shifts. The hierarchy provides a common theoretical underpinning for understanding when and how stability to shifts can be achieved, and in what ways stable distributions can differ. We use it to establish conditions for minimax optimal performance across environments, and derive new algorithms that find optimal stable distributions. By using this new perspective, we empirically demonstrate that that there is a tradeoff between minimax and average performance. (shrink)

While the human papillomavirus vaccine is medically indicated to reduce the risk of genital warts and certain types of cancer, rates of HPV vaccination repeatedly fall short of public health goals. Individual-level factors contributing to low vaccination rates are well documented. However, system-level barriers, particularly the need for parental consent, have been less explored. To date, there is no legal or ethical consensus in the USA regarding whether adolescents might permissibly self-consent to the HPV vaccine. Consequently, there is considerable variability (...) in medical practice at the provider and state level. In this essay, we explore the ethical acceptability of vaccinating adolescents for HPV without parental consent. We argue that the same ethical considerations that justify permitting minors to consent to treatment for sexual and reproductive health care—namely, public health benefit and adolescents’ developing autonomy—similarly justify permitting minors to consent to HPV vaccination. Based on this analysis, we conclude that allowing adolescents to self-consent to the HPV vaccine is ethically justifiable and should be reflected in US state policies. (shrink)

Prior studies provide consistent evidence of deficits for psychopaths in processing verbal emotional material but are inconsistent regarding nonverbal emotional material. To examine whether psychopaths exhibit general versus specific deficits in nonverbal emotional processing, 34 psychopaths and 33 nonpsychopaths identified with Hare's (R. D. Hare, 1991) Psychopathy Checklist-Revised were asked to complete a facial affect recognition test. Slides of prototypic facial expressions were presented. Three hypotheses regarding hemispheric lateralization anomalies in psychopaths were also tested (right-hemisphere dysfunction, reduced lateralization, and reversed (...) lateralization). Psychopaths were less accurate than nonpsychopaths at classifying facial affect under conditions promoting reliance on right-hemisphere resources and displayed a specific deficit in classifying disgust. These findings demonstrate that psychopaths exhibit specific deficits in nonverbal emotional processing. (shrink)

Studies on so-called Change Blindness and Inattentional Blindness have been taken to establish the claim that conscious perception of a stimulus requires the attentional processing of that stimulus. One might contend, against this claim, that the evidence only shows attention to be necessary for the subject to have access to the contents of conscious perception and not for conscious perception itself. This “Methodological Argument” is gaining ground among philosophers who work on attention and consciousness, such as Christopher Mole. I find (...) that, without the supporting evidence of inaccessible consciousness, this argument collapses into an indefensible form of inductive parsimony. The Methodological Argument is thus shown to be unsuccessful when used against the claim that attention is required for conscious perception, though I suggest that it may be successful against the more ambitious claim that attention is necessary for all conscious experience. (shrink)

To aid neuroscientists in determining the ethical limits of their work and its applications, neuroethical problems need to be identified, catalogued, and analyzed from the standpoint of an ethical framework. Many hospitals have already established either autonomy or welfare-centered theories as their adopted ethical framework. Unfortunately, the choice of an ethical framework resists resolution: each of these two moral theories claims priority at the exclusion of the other, but for patients with neurological pathologies, concerns about the patient’s welfare are treated (...) as meaningless without consideration of the patient’s expressed wishes, and vice versa. Ethicists have long fought over whether suffering or autonomy should be our primary concern, but in neuroethics a resolution of this question is essential to determine the treatment of patients in medical and legal limbo. I propose a solution to this problem in the form of ethical dualism. This is a conservative measure in that it retains both sides of the debate: both happiness and autonomy have intrinsic value. However, this move is often met with resistance because of its more complex nature—it is more difficult to make a decision when there are two parallel sets of values that must be considered than when there is just one such set. The monist theories, though, do not provide enough explanatory power: namely, I will present two recently publicized cases where it is clear that neither ethical value on its own (neither welfare nor autonomy) can fully account for how a vegetative patient should be treated. From the neuroethical cases of Terri Schiavo and Lauren Richardson, I will argue that a dualist framework is superior to its monist predecessors, and I will describe the main features of such an account. (shrink)

From its inception with the first number of the magazine of opinion National Review and up to the advent of the Presidency of Richard Nixon the early American conservative movement struggled with the rising tide of civil rights protest and reform. This article examines the correspondence and published primary sources penned by leading members of the American conservative movement so as to offer a comprehensive, chronologically ordered assessment of the evolution of the views on racial inequality offered by the key (...) constituent ideological subcommunities within the American conservative movement: the traditionalists gathered around the pages of National Review, the “neoliberals” led by Milton Friedman y Friedrich von Hayek, the Southern, white conservatives and, lastly, the neoconservatives, which headed by Irving Kristol and Norman Podhoretz articulated much of such views in a manner palatable to a significant segment of the American political mainstream. (shrink)

Sufismus, das Innere, und saria, das Aussere des Islams stellen die beiden Grundpfeiler der Lebensweise des Menschen im Islam dar. Ob der Sufismus jedoch ein rein islamisches Phanomen ist, wurde von vielen Gelehrten diskutiert. Al-Gazali stellte in dieser Diskussion einen bedeutenden Wendepunkt dar. Er deutet den Sufismus als das Aufbauen einer liebevollen und harmonischen Beziehung zu sich selbst, seinem Umfeld und seinem Schopfer. Merdan Gunes geht in seiner Dissertation auf die Entstehung und Entwicklung des Sufismus ein, stellt dabei al-Gazalis (...) Sufismus-Verstandnis dar und erortert die Bedingungen und Gegebenheiten, die auf al-Gazali wirkten. Abschliessend hebt er dessen Einfluss auf den Sufismus im Islam, aber auch auf das Judentum und Christentum hervor, und setzt ihn in Beziehung zu den Philosophen Augustinus, Descartes, Pascal, Spinoza und Erich Fromm. (shrink)