Cancer chemotherapy has been the most common cancer treatment. However, it has side effects that kill both tumor cells and immune cells, which can ravage the patient’s immune system. Chemotherapy should be administered depending on the patient’s immunity as well as the level of cancer cells. Thus, we need to design an efficient treatment protocol. In this work, we study a feedback control problem of tumor-immune system to design an optimal chemotherapy strategy. For this, we first propose a mathematical model (...) of tumor-immune interactions and conduct stability analysis of two equilibria. Next, the feedback control is found by solving the Hamilton–Jacobi–Bellman equation. Here, we use an upwind finite-difference method for a numerical approximate solution of the HJB equation. Numerical simulations show that the feedback control can help determine the treatment protocol of chemotherapy for tumor and immune cells depending on the side effects. (shrink)

Analytical study of logic (Pramāṇa) in Mimamsa school of Hindu philosophy; includes text of Mīmāṃsāsūtra of Jaimini.

Justice; modern philosophy; 20th century.

Yu Kil-chun (1856–1914) was a pioneering theorist in Korea’s Patriotic Enlightenment Movement. Through works such as Sŏyu kyŏnmun, he proposed a new path for the development of Korean civilization. Yu’s encounter with Pak Kyu-su in his early years prompted his interest in Western civilization. He soon decided to study abroad and experience the Japanese and American civilizations first-hand. Based on his experiences, Yu proposed a general blueprint for political reform during the Kabo Reform of 1894. In 1908, he initiated a (...) political reform movement at the provincial level by organizing two groups named Hŭngsadan and Hansŏng Puminhoe. Subsequently, Yu Kil-chun’s enlightenment theory and writings on reform were regarded as a classical model that helped to initiate the modernization of Korea. However, the existing literature concerning Yu’s work exaggerates the progressive role he played and overlooks the logical contradictions and limitations inherent in his ideas. In this article, I conclude that the contradictions in Yu Kil-chun’s enlightenment theory stem from his moral understanding of civilization and the rights of the people. As a result, the project he envisioned ‘to make all people gentlemen’ ultimately focused on how to raise Confucian subjects of an empire rather than how to cultivate modern citizens. (shrink)

Commentary on Bhāṭṭarahasya, Mīmāṃsā treatise, by Khaṇḍadeva, 1575-1665.

Comparative study of Buddhist, Vedanta, and Kashmir Śaiva philosophies.

Ontology ; Knowledge, Theory of ; Personalism.

Jild-i 1: Muntakhab-i ās̲ār-i: Sant Agūstīn, tarjumah-ʼi Muḥammad Taqī Bahrāmī Ḥarrān; Tūmās Akvīnās, tarjumah-ʼi Manūchihr Buzurgmihr; Bārūkh Ispīnūzā, tarjumah-ʼi Abū Ṭālib Ṣārimī; Bilz Pāskāl, tarjumah-ʼi Ḥusayn Kasmāʼī, va muntakhabātī az: Ūpānīshādhā, Dimāpādā, Sūrāngāmāsūtrā, Bhāgavat Gītāyā tarjumah-ʼi Riz̤ā Ṣaddūqī --.

Granthayojanā, anonymous supercommentary, on Śābarabhāṣya, commentary on the Mīmāṃsāsūtra of Jaimini; based on a rare manuscript preserved in the Adyar Library.

Common spatial pattern is an effective algorithm for extracting electroencephalogram features of motor imagery ; however, CSP mainly aims at multichannel EEG signals, and its effect in extracting EEG features with fewer channels is poor—even worse than before using CSP. To solve the above problem, a new combined feature extraction method has been proposed in this study. For EEG signals from fewer channels, wavelet packet transform, fast ensemble empirical mode decomposition, and local mean decomposition were used to decompose the band-pass (...) filtered EEG into multiple time–frequency components, and the corresponding components were selected according to the frequency characteristics of MI or the correlation coefficient between its time–frequency components and the original EEG signal. Furthermore, phase space reconstruction was performed on the selected components after the three time-frequency decompositions, the maximum Lyapunov index was calculated, and the features were reconstructed; then, CSP projection mapping was used for the reconstructed features. The support vector machine probability output model was trained by the obtained three mappings. Probability outputs by three different support vector machines were then obtained. Finally, the classification of test samples was determined by the fusion of the Dempster–Shafer evidence theory at the decision level. The results showed that the accuracy of the proposed method was 95.71% on data set III of BCI competition II, which was 2.88% higher than the existing methods. On data set IIb of BCI competition IV, the average accuracy was 86.60%, which was 2.3% higher than the existing methods. This study verified the effectiveness of the proposed method and provided an approach for the research and development of the MI-BCI system based on fewer channels. (shrink)

Islam and politics; Islamic philosophy; Muslims; ethnic identity.

Hindi interpretation of Mīmāṃsāsūtra of Jaimini.

En este breve comentario discuto algunos aspectos de la interpretación de la epistemología de Davidson que sugiere Willian Duica en su reciente libro. Luego de una presentación somera del libro me centro en tres asuntos centrales de la interpretación de Duica. En primer lugar, argumento que su lectura de la crítica de Davidson al dualismo esquema/contenido es muy restrictiva y deja abierta la posibilidad de un realismo directo empirista. En segundo lugar, argumento que en su lectura el propio Duica se (...) compromete inadvertidamente con un empirismo de este tipo y, de este modo, su interpretación entra en tensión con el coherentismo de Davidson. Finalmente, discuto algunos aspectos de la interpretación que hace Duica de la tesis davidsoniana de la triangulación. In this short comment I discuss some aspects of William Duica's interpretation of Davidson's epistemology in a recent book. After a brief review of the book, I focus on three central issues of Duica's interpretation. First, I argue that his reading of Davidson's criticism of the scheme/content dualism is too restrictive and leaves open the possibility of an empiricist direct realism. Second, I argue in his reading Duica inadvertently commits himself to an empiricism of this sort and, as a result, his interpretation is in tension with Davidson's own coherentism. Finally, I discuss some aspects of Duica's interpretation of Davidsonian triangulation. (shrink)

Classical commentary on Yogasūtra of Patañjali, work on Yoga philosophy; includes complete text of Yogasūtra.

Classical work on Yoga philosophy; Sanskrit text with English, Gujarati, and Hindi translation.

Buddhist canonical treatise on moral ethics.

Drawing on insights from Indian intellectual tradition, this book examines the conception of dharma by Jaimini in his Mīmāṃsāsūtras, assessing its contemporary relevance, particularly within ritual scholarship. Presenting a hermeneutical re-reading of the text, it investigates the theme of the relationship between subjectivity and tradition in the discussion of dharma, bringing it into conversation with contemporary discourses on ritual. The primary argument offered is that Jaimini's conception of dharma can be read as a philosophy of Vedic practice, centred on the (...) enjoinment of the subject, whose stages of transformation possess the structure of a hermeneutic tradition. Offering both substantive and methodological insights into the contentions within the contemporary study of ritual, this book will be of interest to researchers in the fields of Hindu Studies, Ritual Studies, Asian Religion and South Asian Studies. (shrink)