We describe a patient LS, profoundly deaf in both ears from birth, with underdeveloped superior temporal gyri. Without hearing aids, LS displays no ability to detect sounds below a fixed threshold of 60 dBs, which classifies him as clinically deaf. Under these no-hearing-aid conditions, when presented with a forced-choice paradigm in which he is asked to consciously respond, he is unable to make above-chance judgments about the presence or location of sounds. However, he is able to make above-chance judgments about (...) the content of sounds presented to him under forced-choice conditions. We demonstrated that LS has faint sensations from auditory stimuli, but questionable awareness of auditory content. LS thus has a form of type-2 deaf hearing with respect to auditory content. As in the case of a subject with acquired deafness and deaf hearing reported on a previous occasion, LS’s condition of deaf hearing is akin in some respects to type-2 blindsight. As for the case of type 2 blindsight the case indicates that a form of conscious hearing can arise in the absence of a fully developed auditory cortex. (shrink)

Sometimes life's waves knock you down; other times, life might seem to sweep you along powerless, on a wave of malaise. But the choice is always yours to swim back up to the light. World champion surfer Shaun Tomson and Pultizer-nominated poet Noah benShea join forces to guide you down a path of purpose, hope, and faith. This gentle guidebook alternates between Tomson's essays relating the surf experience to life's big waves and benShea's spiritual commentary, accented with full-color (...) surfing photographs. After losing his son, Tomson walked the bitter road of loss and crossed from darkness into the light.The Surfer and the Sage addresses the ten relentless, breaking waves of life, from loss and aging to relationships and depression, and guides you to transformation. It is not a list of rules to follow that guarantee success, health, or wealth, but rather a collection of advice from two guides who have traveled far and wide and suffered deeply, but still look forward to tomorrow with faith and hope. (shrink)

The ribosomal polypeptide tunnel exit is the site where a variety of factors interact with newly synthesized proteins to guide them through the early steps of their biogenesis. In mitochondrial ribosomes, this site has been considerably modified in the course of evolution. In contrast to all other translation systems, mitochondrial ribosomes are responsible for the synthesis of only a few hydrophobic membrane proteins that are essential subunits of the mitochondrial respiratory chain. Membrane insertion of these proteins occurs co‐translationally and is (...) connected to a sophisticated assembly process that not only includes the assembly of the different subunits but also the acquisition of redox co‐factors. Here, we describe how mitochondrial translation is organized in the context of respiratory chain assembly and speculate how alteration of the ribosomal tunnel exit might allow the establishment of a subset of specialized ribosomes that individually organize the early steps in the biogenesis of distinct mitochondrially‐encoded proteins. (shrink)

In this paper, we propose a conceptual framework for constructing a diffusion index of changes in overall perceptions with respect to corruption. The corruption diffusion index we construct lies between 0 (the greatest overall deterioration in corruption perceptions) and 100 (the greatest overall improvement in corruption perceptions) with 50 (no change in corruption perceptions) as the critical reference. The proposed methodology is applied to the 2010/2011 global corruption barometer survey data. Possible refinements of the proposed methodology to capture the potentially (...) multi-dimensional nature of corruption and the practical challenges associated with the empirical implementation are discussed. (shrink)

Worldwide, a significant proportion of teachers retires prematurely for health reasons or at their own request. The study examines whether male and female teachers differ in terms of working conditions and coping with high work demands as well as individual factors that promote early retirement. A cross-sectional study was conducted to collect data from 6,109 full-time teachers in high schools. Weekly working hours from a four-week working time record and psychosocial work stress were used as workloads. In addition, emotional exhaustion (...) and coping strategies that endangered health were recorded in the form of overcommitment and inability to recover. Also, the teachers gave a prediction and reasons for early retirement and made their own suggestions on how to prevent this. The results show that both workloads and emotional exhaustion are comparable between the genders, but women have a greater tendency than men to overcommit and be unable to recover. As ER ratio and emotional exhaustion increase, the chances for both genders to reach the regular retirement age decrease significantly; for health-endangering coping strategies, the relationship is somewhat weaker. The majority of male and female teachers indicates excessive workloads as the main reason for leaving the profession early. In order to protect teachers from high workloads, measures at the organizational, social, and individual level are necessary. Proposals for schools and policy makers are critically discussed on the basis of teacher recommendations. (shrink)

The progress of history rests on the battle for supremacy of competing ideas.... The power and wealth of western countries give them a dominant role in shaping the international public discourse. This is a privileged position... [an] imbalance of voice in the international discourse [that] has built up a dangerous sense of resentment by the silent majority of the world’s people. The dominant bioethical paradigm that provides the context for research ethics discourse has evolved within western philosophy’s powerful normative framework (...) and is built on a relationship model that explains and underpins the obligations doctors have to their patients. In this one-to-one relationship, the doctor is... (shrink)

Die Frage, wie das, was die Vernunft einsieht, dazu motivieren kann, dies auch zu tun, gehört zu den Grundfragen von Kants praktischer Philosophie. Die vorliegende Untersuchung erschließt Kants Antwort auf das Problem der moralischen Motivation innerhalb seiner Handlungstheorie und Moralphilosophie. Neben einer philosophiehistorischen und systematischen Einordnung liefert sie eine umfassende textnahe Analyse der kantischen Argumente, die auch werkgeschichtliche Aspekte berücksichtigt. Auf diese Weise entsteht ein reichhaltiges Bild der kantischen Theorie moralischer Motivation, die in Kants Konzept der Moralbegründung nicht nur verwurzelt (...) ist, sondern dieses auch unterstützt. So ist die Achtung vor dem Gesetz als Modus zu verstehen, in dem sich der Mensch die praktische Norm zu eigen macht. Moralische Gründe erweisen sich nach der hier vorgeschlagenen Interpretation als unbedingte, universal gültige Regeln, deren praktische Bedeutung als subjektive Handlungsgrundsätze und Motive erst durch Kants Theorie der moralisch-rationalen Sensibilität verständlich wird. Kants Ansatz ist damit nicht nur werkintern von Interesse, sondern liefert darüber hinaus einen inspirierenden Beitrag zu einer modernen Theorie praktischer Normativität. (shrink)

The right to health is enshrined in the constitution of the World Health Organization and numerous other international agreements. Yet today, an estimated 5.7 million people die each year from treatable infectious diseases, most of which are susceptible to existing antimicrobials if they were accessible. These deaths occur predominantly among populations living in poverty in low- and middle-income countries, and they greatly exceed the estimated 700,000 annual deaths worldwide currently attributed to antimicrobial resistance. Ensuring universal appropriate access to antimicrobials is (...) not only a critical part of realizing the right to health, it is necessary for mobilizing effective collective action against the development and spread of AMR. (shrink)

What are values? -- What are rules? -- Why are rules useful? -- Breaking the rules -- What is a law? -- Why are laws helpful? -- Committing a crime -- Respecting rules at school -- Respecting rules at home -- Making a difference -- Glossary and index.

Unter dem Begriff der Konversionen erkundet dieser kulturwissenschaftliche Band Formen einer Umkehrung, die einsetzt, wenn die Erfahrung des Beobachtetwerdens als zentraler Bestandteil von Fremderfahrungen anerkannt wird. In den versammelten Texten wird ausgeführt, wie diese aus der ethnologischen Feldforschung gewonnene Erinnerung als Vorbild für andere disziplinäre Perspektiven dienen kann. Die Ethnologie liefert dabei den viel zu lange vernachlässigten Hinweis auf die Wichtigkeit des Blicks des anderen in der Fremderfahrung; die philosophische Perspektive auf interkulturelle Dialoge liefert den Hinweis auf die Wichtigkeit des (...) Sprechens des anderen. Aus diesen Hinweisen ergeben sich Ansprüche an ethnographische und literarische Texte und an andere wissenschaftliche Disziplinen sowie an eine angemessene Lektürepraxis. Die Texte des vorliegenden Bandes versuchen, diese Ansprüche exemplarisch einzulösen. Sie zeigen in einer neuartigen interdisziplinären Zusammenstellung sowohl einzelne Fälle der Umkehrung von Blickrichtungen als auch das Prinzip der Kritik und Erweiterung einer eurozentristischen Philosophie durch die Einführung einer ethnologischen und interkulturellen Perspektive. (shrink)

The contribution focuses on Kant's distinction between right and ethics. According to Kant, ethical as well as juridical laws are laws of freedom. As such they can be recognized by rational beings as unconditionally binding. The decisive difference between right and ethics consists in the way that obligations are required in their respective realms of legislation. While ethical legislation cannot be external and ethics is also concerned with inner motivations, juridical duties do not command dispositions but specific actions.

John's most characteristic word for salvation, then, is life, and ultimately it is not a quality, a state, to which Jesus brings men, but Jesus himself.

Animals have been and will continue to be used in educational programs, but some concerns about the responsibility for assuring their proper care and humane use need to be discussed. Research animals have been regulated and monitored quite successfully by Institutional Animal Care and Use Committees (IACUC). These Committees are extending their responsibilities to cover animals used in educational programs. Three common roles of these IACUCs are described, including oversight, investigative and training responsibilities. Guidelines developed for faculty using animals at (...) the University of Florida are presented and discussed. (shrink)

Owen Ware is already well-known among Kant scholars since he published several insightful contributions on Kant’s practical philosophy. Ware has now collected five of his essays on Kant’s practical philosophy in a book. Kant’s Justification of Ethics, OUP 2021, largely refers back to some of his previously published papers. The guiding idea of the book, and a crucial feature of Ware’s approach, is the claim that Kant’s ethics and metaphysics form a unit and that the central questions of Kant’s moral (...) philosophy have to be analyzed against this methodological background. With this assertion he opposes what he believes has been an observable research trend for a long time. (shrink)

Hume's concept of justice as an artificial virtue is still controversial. In contrast to the more traditional research debate, the text defends a new reading of Hume's peculiar conception of justice, which understands his argument for justice as a special form of an internalism of practical reasons. It shows that his motivational justification for the virtue of justice proves to be consistent within his affect theory and yet systematically vulnerable.