Successful surgical treatment of patients with focal drug-resistant epilepsy remains challenging, especially in cases for which it is difficult to define the area of cortex from which seizures originate, the seizure onset zone. Various diagnostic methods are needed to select surgical candidates and determine the extent of resection. Interictal magnetoencephalography with source imaging has proven to be useful for presurgical evaluation, but the use of ictal MEG data remains limited. The purpose of the present study was to determine whether pre-ictal (...) variations of spectral properties of neural activity from ictal MEG recordings are predictive of SOZ location.We performed a 4 h overnight MEG recording in an 8-year-old child with drug-resistant focal epilepsy of suspected right fronto-temporal origin and captured one ~45-s seizure. The patient underwent a right temporal resection from the anterior temporal neocortex and amygdala to the mid-posterior temporal neocortex, sparing the hippocampus proper. She remains seizure-free 21 months postoperatively. The histopathological assessment confirmed frank focal cortical dysplasia type IIa in the MEG-defined SOZ, which was based on source imaging of averaged ictal spikes at seizure onset. We investigated temporal changes together with spatial differences in spectral parameters of background brain activity, namely the aperiodic broadband offset and slope, and assessed how they confounded the interpretation of apparent variations of signal power in typical electrophysiological bands. Our data show that the SOZ was associated with a higher aperiodic offset and exponent during the seizure compared to control regions. Both parameters increased in all regions from 2 min before the seizure onwards. Regions anatomically closer to the SOZ also expressed higher values compared to contralateral regions, potentially indicating ictal spread. We also show that narrow-band power changes were caused by these fluctuations in the aperiodic component of ongoing brain activity. Our results indicate that the broadband aperiodic component of ongoing brain activity cannot be reduced to background noise of no physiological interest, and rather may be indicative of the neuropathophysiology of the SOZ. We believe these findings will inspire future studies of ictal MEG cases and confirm their significance. (shrink)

A philosopher argues that state-sponsored cyberattacks against central military or civilian targets are always acts of war. What is this philosopher doing? According to conceptual analysts, the philosopher is making a claim about our concept of war. According to philosophical realists, the philosopher is making a claim about war per se. In a quickly developing literature, a third option is being explored: the philosopher is engineering the concept of war. On this view, the philosopher is making a proposal about which (...) concept we should have – even if it deviates from the extant concept, and even if it does not capture ‘what war really is’. The activity or method of proposing such revisionary definitions, as well as the metaphilosophical reflection on it, has become known as conceptual engineering. (shrink)

Conceptual engineering concerns the assessment and improvement of our concepts. But how can proposals to engineer concepts be implemented in the real world? This is known as the implementation challenge to conceptual engineering. In this paper, I am concerned with the meta-philosophical implications of the implementation challenge. Specifically, must we overcome the implementation challenge prior to undertaking conceptual engineering? Some critics have recently answered this question affirmatively. I intend to show that they are mistaken. I argue as follows. First, successful (...) implementation is not an integral part of conceptual engineering. Second, the idea that the value of conceptual engineering relies on successful implementation is in tension with widespread assumptions about normative theorizing. (shrink)

Bayesian approaches for estimating multilevel latent variable models can be beneficial in small samples. Prior distributions can be used to overcome small sample problems, for example, when priors that increase the accuracy of estimation are chosen. This article discusses two different but not mutually exclusive approaches for specifying priors. Both approaches aim at stabilizing estimators in such a way that the Mean Squared Error of the estimator of the between-group slope will be small. In the first approach, the MSE is (...) decreased by specifying a slightly informative prior for the group-level variance of the predictor variable, whereas in the second approach, the decrease is achieved directly by using a slightly informative prior for the slope. Mathematical and graphical inspections suggest that both approaches can be effective for reducing the MSE in small samples, thus rendering them attractive in these situations. The article also discusses how these approaches can be implemented in Mplus. (shrink)

This chapter examines the series of drastic epistemological and methodological transformations in the status of hypotheses in British natural philosophy during the seventeenth century. It explains that hypotheses played a rather marginal role in Francis Bacon's methodological thought because he believed they lacked any physical content, although they occupied a centre stage in the Bacon-inspired natural philosophy program of Robert Boyle and Robert Hooke. The chapter mentions that Boyle and Hooke provided a new definition of hypothesis, which is that of (...) something conceived of as causally sufficient and probable explications of natural phenomena that stand in an evidential relation to the natural phenomena they serve to elucidate. (shrink)

This paper deals with the question of whether nature sports are to be counted among the (traditional) sports and Kevin Krein’s recent argument, based on sporting excellence, as to why they should. Krein argues that sports as such are ultimately about sporting excellence and because both so-called traditional sports and nature sports fulfil that criterion, nature sports belong in the sport domain. Here, I show that Krein’s argument rests on an equivocation between two concepts of sporting excellence. Sporting excellence in (...) traditional sports is connected to sporting success. Here agon (contest or competition) dictates or frames areté (striving for excellence). This is not the case for sporting excellence in nature sports, as these are not competitions. We are dealing with two different concepts of sporting excellence and Krein’s argument, based on sporting excellence, must be rejected. It gives no basis for including nature sports in the sport domain. (shrink)

Connecting human minds to various technological devices and applications through brain-computer interfaces (BCIs) affords intriguingly novel ways for humans to engage and interact with the world. Not only do BCIs play an important role in restorative medicine, they are also increasingly used outside of medical or therapeutic contexts (e.g., gaming or mental state monitoring). A striking peculiarity of BCI technology is that the kind of actions it enables seems to differ from paradigmatic human actions, because, effects in the world are (...) brought about by devices such as robotic arms, prosthesis, or other machines, and their execution runs through a computer directed by brain signals. In contrast to usual forms of action, the sequence does not need to involve bodily or muscle movements at all. A motionless body, the epitome of inaction, might be acting. How do theories of action relate to such BCI-mediated forms of changing the world? We wish to explore this question through the lenses of three perspectives on agency: subjective experience of agency, philosophical action theory, and legal concepts of action. Our analysis pursues three aims: First, we shall discuss whether and which BCI-mediated events qualify as actions, according to the main concepts of action in philosophy and law. Secondly, en passant, we wish to highlight the ten most interesting novelties or peculiarities of BCI-mediated movements. Thirdly, we seek to explore whether these novel forms of movement may have consequences for concepts of agency. More concretely, we think that convincing assessments of BCI-movements require more fine-grained accounts of agency and a distinction between various forms of control during movements. In addition, we show that the disembodied nature of BCI-mediated events causes troubles for the standard legal account of actions as bodily movements. In an exchange with views from philosophy, we wish to propose that the law ought to reform its concept of action to include some, but not all, BCI-mediated events and sketch some of the wider implications this may have, especially for the venerable legal idea of the right to freedom of thought. In this regard, BCIs are an example of the way in which technological access to yet largely sealed-off domains of the person may necessitate adjusting normative boundaries between the personal and the social sphere. (shrink)

Worte verletzen und kränken. Woher aber kommt diese Verletzungsmacht? Während in der deutschsprachigen Philosophie Sprache meist als Gegenmittel zur Gewalt begriffen wird, hat die US-amerikanische Debatte um "hate speech" gezeigt, dass das Sprechen Gewalt nicht nur androhen oder verhindern, sondern selbst eine Form von Gewaltausübung sein kann. Wie nun sind sprachliche Verletzung, Ausgrenzung und Missachtung zu erklären und zu verstehen? Aus der Sicht verschiedener Disziplinen untersuchen die Beiträge dieses Bandes, welcher Logik, Grammatik und Rhetorik unser verletzendes Sprechen gehorcht. Mit Beiträgen (...) von u.a. Pierre Bourdieu, Penelope Brown/Stephen Levinson, Harold Garfinkel und Rae Langton. Steffen Kitty Herrmann (M.A.) und Hannes Kuch (M.A.) sind wissenschaftliche Mitarbeiter am Institut für Philosophie der Freien Universität Berlin und arbeiten im Forschungsprojekt”Zur Performanz sprachlicher Gewalt“am Sonderforschungsbereich 447”Kulturen des Performativen“. Sybille Krämer ist Professorin für Philosophie an der FU Berlin und Permanent Fellow am Wissenschaftskolleg Berlin. (shrink)

The idea of "spirit" has manifold meanings and plays a crucial role in Early Modern medicine, psychology, religion, natural philosophy, and cosmology. This book contains twenty papers, written by international experts; it explores how those disciplines conceived of the spirits and shows that knowledge of the spirits is an essential prerequisite for the understanding of Renaissance literature and music. The volume focuses on the way in which the spirits act upon the soul's perception, imagination, and cognition, and on the cultural (...) practices which aim to use, purge, or ban the spirits. (shrink)

Wirth beschreibt in diesem Buch Volkstum und Weltmacht in der Geschichte, im Original 1904 erschienen.

In this article, we draw on established views of CSR dysfunctionalities to show how and why CSR is regularly observed to be both shaped by and supportive of capitalism. We proceed to show that these dysfunctionalities are maintained by both the pro- and anticapitalist approaches to CSR, both of which imply an ill-defined separation of the economy and society as well an overly strong problem or solution focus on political and economic issues. Finally, we present a post-capitalist approach to CSR (...) that overcomes (1) the ill-defined separation of the economy and society, (2) the capitalist bias towards economic rationalities, and (3) the overidentification of society with its political system; this approach thus helps to manage the abovementioned CSR dysfunctionalities. (shrink)

George Spencer Brown, a polymath and author of Laws of Form, brought together mathematics, electronics, engineering and philosophy to form an unlikely bond. This book investigates Design with the NOR, the title of the yet unpublished 1961 typescript by Spencer Brown. The typescript formed through the author's experiences as technical engineer and developer of a new form of switching algebra for Mullard Equipment LTD., a British manufacturer of electronic components. Related essays contextualise the typescript drawing on a variety of backgrounds (...) from mathematics and engineering to philosophy and sociology. (shrink)

La notion de "Bildung" (culture) de Humboldt au National-socialisme dans les états allemands modernes.

Our outline points out three aspects of a new post-modern methodology in psychology: liberal, pluralistic, and more tolerant: liberal because it rejects rules that are too strict in favor of more freedom in the choice of method, pluralistic because it conveys an “almost anything goes” attitude toward methods, and more tolerant because mutual tolerance among researchers is vital for a pluralism of methods. Psychological phenomena are complex and can best be understood by using different methods. However, to get things working, (...) tolerance must actively be lived. Of course, much depends on our own willingness as researchers but also on the system’s arrangements. Psychology could be more colorful, and we could all have more fun if we were to be more committed to such a methodology. (shrink)

For the living, death has a moral dimension. When we confront death and dying in our own lives and in the lives of others, we ask questions about the good, right, and fitting as they relate to our experiences of human mortality. When others die, the living are left with moral questions--questions that often generate personal inquiry as to whether a particular death was "good" or whether it was tragic, terrifying, or peaceful. In The Ethics of Death, the authors, one (...) a philosopher and one a religious studies scholar, undertake an examination of the deaths that we experience as members of a larger moral community. Their respectful and engaging dialogue highlights the complex and challenging issues that surround many deaths in our modern world and helps readers frame thoughtful responses. Unafraid of difficult topics, Steffen and Cooley fully engage suicide, physician-assisted suicide, euthanasia, capital punishment, abortion, and war as areas of life where death poses moral challenges." -- Publisher's description. (shrink)

This paper discusses the logical space of alternative conceptual engineering projects, with a specific focus on (1) the processes, (2) the targets and goals, and (3) the methods of such projects. We present an overview of how these three aspects interact in the contemporary literature and discuss those alternative projects that have yet to be explored based on our suggested typology. We show how choices about each element in a conceptual engineering project constrain the possibilities for the others, thereby giving (...) rise to distinct groupings of possible projects under the banner of conceptual engineering. We conclude with a critical reflection on the potential ethical issues that arise as a result of effectively putting conceptual engineering into practice. (shrink)

Unlike conceptual analysis, conceptual engineering does not aim to identify the content that our current concepts do have, but the content which these concepts should have. For this method to show the results that its practitioners typically aim for, being able to change meanings seems to be a crucial presupposition. However, certain branches of semantic externalism raise doubts about whether this presupposition can be met. To the extent that meanings are determined by external factors such as causal histories or microphysical (...) structures, it seems that they cannot be changed intentionally. This paper gives an extended discussion of this ‘externalist challenge’. Pace Herman Cappelen’s recent take on this issue, it argues that the viability of conceptual engineering crucially depends on our ability to bring about meaning change. Furthermore, it argues that, contrary to first appearance, causal theories of reference do allow for a sufficient degree of meaning control. To this purpose, it argues that there is a sense of what is called ‘collective long-range control’, and that popular versions of the causal theory of reference imply that people have this kind of control over meanings. (shrink)

This is a book symposium on Steffen Borge’s The Philosophy of Football. It has contributions from William Morgan, Murray Smith and Brian Weatherson with replies from Borge.

pt. 1. Newton's causal methodology -- pt. 2. Newton's methodology : "the best way of arguing in natural philosophy" -- pt. 3. Newton's theology.

Is the endeavour to restore perceptive brain functions by electronic implants the first step on the way to create bionic cyborgs? Can we augment or multiply our senses by directly contacting computer chips to the brain? Will bio-implants influence and permanently change human psyche?

Die neu gegründete Reihe Paracelsus Studien bietet ein wissenschaftliches Forum für interdisziplinäre Forschungen, die sich kultur- und wissenschaftshistorisch Modellen eines ganzheitlichen Weltbildes widmen und den Dialog zwischen den Disziplinen anregen. Der frühneuzeitliche Alchemist, Mystiker, Theologe und Philosoph Paracelsus (1493-1541) dient hierfür als Leitfigur und Vorbild. Als eröffnender Sammelband fokussiert Mystik und Natur Epochen und Persönlichkeiten der Geistesgeschichte von der Spätantike bis in die Gegenwart, die sich der Integration von Spiritualität und Wissenschaft widmeten: Hildegard von Bingen, Jakob Böhme, Emanuel Swedenborg, Josef (...) Goerres und Johann Wolfgang von Goethe stehen ebenso im Mittelpunkt der Untersuchungen wie gegenwärtige ganzheitliche Ansätze und ihre historischen Bezüge. (shrink)

Als Signatur moderner demokratischer Gesellschaften gilt heute weithin, was John Rawls zu Beginn der 1990er Jahre als „vernünftigen Pluralismus“ bezeichnet hat. Mit ihm einher geht die Frage, wie divergierende Lebensformen miteinander ins Gespräch gebracht werden können und wie sich dabei zu legitimen politischen Urteilen kommen lässt. Ich werde in meinem Beitrag argumentieren, dass sich die genannte Frage lösen lässt, wenn wir uns der jüngeren Diskussion von Arendts Theorie der Urteilskraft von Linda Zerilli zuwenden und diese mit Rahel Jaeggis Überlegungen zur (...) Kritik von Lebensformen verbinden. Dafür werde ich zunächst Arendts Überlegungen zur politischen Urteilskraft rekonstruieren und zeigen, wie diese Kants Modell der ästhetischen Urteilskraft auf den Bereich des Politischen zu übertragen versucht. Ich werde argumentieren, dass Arendt diese Transposition nur teilweise gelingt und eine Reihe von wichtigen Fragen ungelöst bleibt. Arendts Überlegungen sind damit jedoch keineswegs obsolet, sondern müssen vielmehr weiter gedacht werden. Zerilli hat hierfür jüngst einen wegweisenden Vorschlag vorgelegt, der Arendts Theorie der Urteilskraft nicht mehr im Ausgang von Kant, sondern von Wittgenstein zu denken versucht. Die damit einhergehende Perspektivverschiebung erlaubt es, den Streit zwischen divergierenden Lebensformen mit Jaeggi als eine mit den Mitteln der immanenten Kritik geführte Auseinandersetzung um deren Lernfähigkeit zu begreifen, was am Beispiel des Streits zwischen den Lebensformen der Kleinfamilie und der Kommune deutlich gemacht werden soll. (shrink)

Currently, electronic agents are being designed and implemented that, unprecedentedly, will be capable of performing legally binding actions. These advances necessitate a thorough treatment of their legal consequences. In our paper, we first demonstrate that electronic agents behave structurally similar to human agents. Then we study how declarations of intention stated by an electronic agent are related to ordinary declarations of intention given by natural persons or legal entities, and also how the actions of electronic agents in this respect have (...) to be classified under German law. We discuss four different approaches of classifying agent declarations. As one of these, we propose the concept of an electronic person (i.e., agents with limited liability), enrolment of agents into an agent register, and agent liability funds as means to serve the needs of all contracting parties. (shrink)