This study explored spatial navigation alongside several other cognitive abilities that are thought to share common underlying neurocognitive mechanisms (e.g., the capacity for self-projection, scene construction, or mental simulation), and which we hypothesised may be impaired in autism spectrum disorder (ASD). Twenty intellectually high-functioning children with ASD (with a mean age of ~8 years) were compared to 20 sex, age, IQ, and language ability matched typically developing children on a series of tasks to assess spatial navigation, episodic memory, episodic future (...) thinking (also known as episodic foresight or prospection), theory of mind, relational memory, and central coherence. This is the first study to explore these abilities concurrently within the same sample. Spatial navigation was assessed using the “memory island” task, which involves finding objects within a realistic, computer simulated, three-dimensional environment. Episodic memory and episodic future thinking were assessed using a past and future event description task. Theory of mind was assessed using the “animations” task, in which children were asked to describe the interactions between two animated triangles. Relational memory was assessed using a recognition task involving memory for items (line drawings), patterned backgrounds, or combinations of items and backgrounds. Central coherence was assessed by exploring differences in performance across segmented and unsegmented versions of block design. Children with ASD were found to show impairments in spatial navigation, episodic memory, episodic future thinking, and central coherence, but not theory of mind or relational memory. Among children with ASD, spatial navigation was found to be significantly negatively related to number of repetitive behaviours. In other words, children who showed more repetitive behaviours showed poorer spatial navigation. The theoretical and practical implications of the results are discussed. (shrink)

This commentary focuses on evidence from autism concerning the relation between metacognition and mindreading. We support Carruthers' rejection of models 1 (independent systems) and 3 (metacognition before mindreading), and provide evidence to strengthen his critique. However, we also present evidence from autism that we believe supports model 2 (one mechanism, two modes of access) over model 4 (mindreading is prior).

ABSTRACTThis article examines William Barclay's response to Jean Boucher's De Justa Abdicatione Henrici Tertii in view of the complexities of Catholic political thought in this post-Tridentine period. It argues that Barclay's famous category of ‘monarchomach’ is problematic for its avoidance of the issue of confessional difference, and that on questions of the relationship between the respublica and the ecclesia Barclay struggled to find an adequate response to Boucher in his De Regno et Regali Potestate. His De Potestate Papae is treated (...) as the intellectual extension of his battle with Boucher, and more broadly his confrontation with the position of the Catholic League and Jesuits on indirect papal power. By considering Barclay's works in the context of French Gallicanism and the Catholic League in the French Wars of Religion, this discussion aims to reposition Barclay in relation to other Catholic political theorists and thereby re-evaluate the category of Catholic resistance theory. (shrink)

We dedicate this book to John Thibaut. He was mentor and personal friend to one of us, and his work had a profound intellectual influence on both of us. We were both strongly influenced by Thibaut's insightful articulation of the importance to psychology of the concept of pro cedural justice and by his empirical work with Laurens Walker in reactions to legal institu demonstrating the role of procedural justice tions. The great importance we accord the Thibaut and Walker work is (...) evident throughout this volume. If anyone person can be said to have created an entire field of inquiry, John Thibaut created the psychological study of procedural justice. (To honor Thibaut thus in no sense reduces our recognition of the contributions of his co-worker, Laurens Walker, in the creation of the field. We are as certain that Walker would endorse our statement as we are that Thibaut, with characteristic modesty, would demur from it. ) Even to praise Thibaut in this fashion falls short of recognizing all of his contributions to procedural justice. Not only did he initiate the psy chological study of the topic, he also built much of the intellectual foun dation upon which the study of procedural justice rests. Thibaut's work with Harold Kelley (1959; Kelley & Thibaut, 1978) created a social psy chological theory of interdependence that, among many other applica tions, serves as the basis for one of the major models of the psychology of procedural justice. (shrink)

Qu'ont en commun Diderot, D'Alembert et l'abbé de Saint-Pierre? Voisenon et Pluche? Fontenelle et Sade? La Font de Saint-Yenne et Condillac? Casanova et Buffon? Batteux et Barruel? Peu de chose a priori réunit les auteurs qui dialoguent au sein de ce volume, sinon que tous, quel que soit leur domaine de réflexion, ont été amenés durant leur parcours intellectuel à se confronter à la question du système et à se prononcer sur sa nécessité, sa pertinence et sa valeur. A lire (...) les études ici rassemblées, il apparaît que la pensée du système innerve les champs du savoir et de la création au XVIIIe siècle. Mais ce tropisme systématique étonnamment persistant ne signifie nullement la permanence de la valeur accordée à l'esprit de système : ces systèmes omniprésents traduisent plutôt la perte de majesté du système, détrôné par d'autres manières de penser et d'écrire le monde et les hommes."--Page 4 of cover. (shrink)

Mental causation has been a hotly disputed topic in recent years, with reductive and non-reductive physicalists vying with each other and with dualists over how to accommodate, or else to challenge, two widely accepted metaphysical principles—the principle of the causal closure of the physical domain and the principle of causal non-overdetermination—which together appear to support reductive physicalism, despite the latter’s lack of intuitive appeal. Current debate about these matters appears to have reached something of an impasse, prompting the question of (...) why this should be so. One possibility well worth exploring is that, while this debate makes extensive use of ontological vocabulary—by talking, for instance, of substances, events, states, properties, powers, and relations—relatively little attempt has been made within the debate itself to achieve either clarity or agreement about what, precisely, such terms should be taken to mean. Hence, the debate has become somewhat detached from broader developments in metaphysics and ontology, which have lately been proceeding apace, providing us with an increasingly rich and refined set of ontological categories upon which to draw, as well as a much deeper understanding of how they are related to one another. In preparing this volume, the editors invited leading metaphysicians and philosophers of mind to reflect afresh upon the problem of mental causation in the light of some of these recent developments, with a view to making new headway with one of the most challenging and seemingly intractable issues in contemporary philosophy. (shrink)

It is argued that a radical relocation of subjectivity began several thousand years ago. A subjectivity experienced in the centric region of the heart, and in the body as a whole, began to be avoided in favor of the eccentric head as a new location of subjectivity. In ancient literature, for example in Homer's epics, the heart and various other bodily organs were described as centers of subjectivity and organs of perception for spiritual experience and communion with others and the (...) world. Mind and body were integrated. Bur also in the early historical record, as in the Old Testament, the heart and body were increasingly described as rebellious and rejected as impure. Head and heart, mind and body, became estranged. The body was judged an unsuitable, impure vessel for spiritual experience. This change in the location of subjectivity presaged the later development of Platonic, Gnostic, Christian, and Cartesian distinctions favoring mind over and against the body. It may also have contributed to some of the characteristic psychological and pathological processes (e.g., psychosomatic illnesses, repression, narcissism) currently attributed to the psychology of the modern Western, and specifically, North American self. (shrink)

Homophobia has decreased in past decades, but gut-level disgust towards gay men lingers. It has been suggested that disgust can be reduced by inducing its proposed opposite emotion, elevation. Rese...

Selective protein degradation maintains cellular homeostasis, but this process is disrupted in many diseases. Targeted protein degradation (TPD) approaches, built upon existing cellular mechanisms, are promising methods for therapeutically regulating protein levels. Here, we review the diverse palette of tools that are now available for doing so throughout the gene expression pathway and in specific cellular compartments. These include methods for directly removing targeted proteins via the ubiquitin proteasome system with proteolysis targeting chimeras (PROTACs) or dephosphorylation targeting chimeras (DEPTACs). Similar (...) effects can also be achieved through the lysosomal system with autophagy‐targeting chimeras (AUTACs), autophagosome tethering compounds (ATTECs), and lysosome targeting chimeras (LYTACs). Other methods act upstream to degrade RNAs (ribonuclease targeting chimeras; RIBOTACs) or transcription factors (transcription factor targeting chimeras; TRAFTACs), offering control throughout the gene expression process. We highlight the evolution and function of these methods and discuss their clinical implications in diverse disease contexts. (shrink)

Introduction: People with Spinal Cord Injury are at risk of feeling socially disconnected. Competitive esports present an opportunity for people with SCI to remotely engage in a community. The aim of this study is to discuss barriers to esports participation for people with SCI, present adaptive solutions to these problems, and analyze self-reported changes in social connection.Materials and Methods: We presented a descriptive data collected in the process of a quality improvement initiative at Mount Sinai Hospital. In 2019, seven individuals (...) with cervical SCI and quadriplegia participated in a special interest group on esports. Group scores were then analyzed for evidence of between subjects variability using a single sample t-test. A Pearson's correlation was conducted to determine the relationship between social connectedness and demographic data.Results: All players experienced functional limitations as a result of their injury but managed to design personalized gaming setups with adaptive equipment that allowed them to successfully compete in esports. All players reported a positive change in perceived social connectedness after participating in the special interest group. Score on Social Connectedness Scale negatively correlated with Time since injury.Discussion: It is feasible to create adaptive gaming setups that can be used by people with differing degrees and severity of SCI in a competitive esports environment. Technology and adaptive competitive esports have a potential to improve social connectedness and inclusion in people with quadriplegia. Further research on efficacy and effectiveness of these inclusive environments and their effects on quality of life, activity, and participation is warranted. (shrink)

Introduction: Screen-based and mobile technology has grown at an unprecedented rate. However, little is understood about whether increased screen-use affects executive functioning, the range of mental processes that aid goal attainment and facilitate the selection of appropriate behaviors. To examine this, a systematic review was conducted.Method: This systematic review is reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. A comprehensive literature search was conducted using Web of Science, MEDLINE, PsycINFO and Scopus databases to identify (...) articles published between 2007 and March 2020, examining the use of mobile technologies on aspects of EF in healthy adults aged 18–35 years. In total 6079 articles were screened by title, and 39 screened by full text. Eight eligible papers were identified for inclusion. Our methods were pre-registered on the PROSPERO international prospective register of systematic reviews.Results: A total of 438 participants were included across the eight studies. Five of the eight studies examined more than one EF. Five studies measured inhibition, and four studies measured decision-making. Smartphone use was negatively associated with inhibition and decision-making. Working memory performance was found to be improved by increased time engaging in video games and by refraining from smartphone use prior to bedtime. Quality assessments indicated high risk of methodological biases across the studies and a low quality of evidence for determining the relationship between technology use and executive functioning.Conclusions: This review highlights the scarcity of the literature in this area. It presents a call for rigorous and objective research to further our understanding of the impact of mobile technology on different aspects of executive function. (shrink)

La réception extraordinairement féconde de Heidegger, singulièrement en France, est entrée dans une phase nouvelle et le moment semble propice pour demander « ce qui est vivant » et « ce qui est mort » dans sa pensée, en interrogeant ses percées réelles comme ses impasses. La publication de l'édition intégrale en 102 volumes touche à sa fin : au-delà de tous les textes publiés du vivant de Heidegger, nous avons désormais à disposition tous les cours de Fribourg et de (...) Marbourg, les traités « ésotériques » rédigés dans le sillage des Beiträge dans les années 1930-1940 et les Cahiers noirs de cette période. Le colloque de Québec, documenté par le présent ouvrage et complété par des textes inédits, se concentrait moins sur le maître-ouvrage Être et temps que sur la période complexe initiée avec la conférence "L'essence de la vérité". C'est en effet à partir du « tournant » des années 1930 qu'émergent les concepts qui guident la pensée de l'Ereignis inscrite dans une « Histoire de l'être », selon ses dimensions phénoménologique et herméneutique, mais aussi théologique et politique.Les contributions ici réunies, portant sur l'histoire, la technique, l'art, le politique, le mythe ou le divin, tentent d'éclairer la nature et les limites de ce legs philosophique majeur du XXe siècle en envisageant la question de sa postérité et de son actualité pour nous, aujourd'hui. (shrink)

"La philosophie d'Emmanuel Levinas est souvent présentée comme une philosophie de l'éthique et fut associée à des notions telles que le visage, autrui ou la responsabilité. Or, ces notions peuvent être comprises à partir d'un primat accordé au temps. Levinas propose en effet une philosophie du temps dans un dialogue avec d'autres pensées (Lavelle, Bergson, Rosenzweig, Husserl, Heidegger). Rappelant combien les premiers écrits de Levinas délivrent une philosophie du sujet et de l'instant, l'ouvrage se propose d'expliquer le développement de cette (...) philosophie et de son éthique à partir de son rapport à la temporalité. Si autrui délivre l'avenir sur le mode du désir, Sophie Galabru montre comment, à partir de 1963, autrui s'aborde chez Levinas comme un passé immémorial et impose la violence des remords et de la culpabilité. C'est donc tout le sens et le rythme du désir qui se trouvent radicalement infléchis."--Page 4 de la couverture. (shrink)

Epiphanies is a philosophical exploration of epiphanies, peak experiences, 'wow moments', or ecstasies as they are sometimes called. What are epiphanies, and why do so many people so frequently experience them? Are they just transient phenomena in our brains, or are they the revelations of objective value that they very often seem to be? What do they tell us about the world, and about ourselves? How, if at all, do epiphanies fit in with our moral systems and our theories of (...) how to live? And how do epiphanic experiences fit in with the rest of our lives? These are Sophie Grace Chappell's questions in this ground-breaking new study of an area of inquiry that has always been right under our noses, but remains surprisingly under-explored in contemporary philosophy. (shrink)

La philosophie doit-elle, aujourd'hui encore, quelque chose à la langue, à la culture et à la pensée grecques? Sophie Klimis, en s’entretenant avec Frank Pierobon, réfléchit sur ces manières de penser et ces nouvelles formes de vie, inventées en Grèce ancienne, conjointement à l’émergence du projet politique de la démocratie. Elle propose un voyage vers ces temps lointains et toujours inspirants, pour en percevoir les ressources, notamment en montrant comment des dispositifs institutionnels et symboliques – dont ceux du choeur (...) dans le théâtre – structurent la Cité et forment ses citoyens. (shrink)

Qu’est-ce qu’une spécialiste de la philosophie grecque peut bien avoir à transmettre à un auditoire de 500 juristes débutant(e)s? Le plaisir de penser, dans la rigueur et l’audace. Le goût foncièrement démocratique pour le débat, c’est-à-dire la nécessité de confronter sa pensée à celle d’autrui, fût-elle sous-tendue par une raison contradictoire. Comment faire? Plutôt qu’un parcours classique dans l’histoire de la philosophie, l’auteur a choisi de construire le cheminement d’une enquête en deux étapes. La première, placée sous le signe d’Oedipe, (...) interroge l’énigme de l’humain. Elle fera voyager de la description poétique de l’homme comme mortel éphémère chez Homère à l’être-vers la- mort selon Heidegger, de la définition de l’homme comme animal rationnel d’Aristote à son retournement en animal fou par Castoriadis. La seconde étape prolongera ce questionnement en l’axant sur le collectif. Elle portera sur l’invention de la politique : de la cité grecque à l’État moderne, comment les sociétés humaines se sont-elles organisées? Qu’ont-elles institué comme fondement à leur communauté? Une grande attention sera également accordée à l’étude de philosophes contemporains, qui, en se fondant sur la discussion des penseurs grecs et modernes, ont proposé de nouvelles manières de penser la démocratie, la liberté et le pouvoir, les formes de vie et les types humains, les actions et les passions propres au politique. Plongeant dans les racines du passé pour mieux comprendre le présent et inventer le futur, cet ouvrage intéressera en réalité toutes les personnes désireuses de s’engager dans une réflexion citoyenne. (shrink)

In his book Autonomous Knowledge J. Adam Carter argues that the possibility of radical cognitive enhancement shows the need for epistemology to be significantly updated. Reflection on the possibility of such enhancement shows that doxastic autonomy matters. If a belief fails to be autonomous, it cannot qualify as knowledge. Sects. 1-3 of this paper introduce the key components of Carter's autonomy framework and his considerations on the value of knowledge (including his proposed solution to the value problem, i.e. the challenge (...) of accounting for why knowledge has greater value than any of its proper parts). Sects. 4-7 offer a critical appraisal of Carter's framework. We are not convinced that Carter has succeeded in showing that there is an autonomous belief condition on knowledge. In this paper, however, we shall not engage with this issue. Instead, for the sake of our critical discussion, we shall assume that autonomous belief is a condition on knowledge and engage Carter on a cluster of issues concerning axiology. (shrink)

This paper introduces and motivates the claim that we possess doxastic agent’s awareness. I argue that this is a form of agentive awareness concerning our belief states that we enjoy in virtue of deliberating and judging. Namely, we experience these activities as those of making up our mind and keeping it made up regarding our beliefs. Following related work in the philosophy of action, I understand this awareness as a form of conscious experience which can then ground our self-ascriptions. As (...) such, this enables me to also propose a new account of self-knowledge of belief and the way in which deliberating and concluding that p can warrant us in self-ascribing the belief that p (i.e., employing the so-called ‘transparency method’). Philosophers often appeal to our arguably agentive relation to our beliefs in explaining this. I, though, I extend work in the philosophy of action in a way that is surprisingly flatfooted way given that belief is a state and not an action. (shrink)

Face à la nouvelle sensibilité de l'homme contemporain envers les questions écologiques, à l’importance qu’il accorde au soin de la planète, et dans le sillage de la publication de Laudato Si’, la vision de Teilhard de Chardin apparaît à nouveau actuelle. Bien que les questions et l’état des sciences aient changé considérablement depuis sa mort en 1955, la portée cosmologique de la christologie teilhardienne fait de la perspective du jésuite paléontologue une source inespérée pour une pratique chrétienne adaptée aux exigences (...) du monde moderne. À partir de sa notion d’Église en tant que Corps cosmique du Christ, où toutes les créatures de notre vaste univers sont englobées au sein de la sphère ecclésiale elle-même, la communion entre les êtres s’étend au-delà des êtres humains, fondant un profond respect pour toutes les créatures. Le présent ouvrage cherche à préciser et à justifier, d’un côté, l’insertion de Teilhard au sein de la tradition chrétienne et à envisager, d’un autre, les conséquences pratiques de cette ecclésiologie écologique, notamment dans la spiritualité, l’éthique et la liturgie. Andreas Gonçalves Lind est un prêtre jésuite luso-allemand qui, pour le moment, fait une thèse doctorale sur la phénoménologie henryenne de la Vie à l’Université de Namur comme boursier de la FCT – Fundação para a Ciência e Tecnologia (Portugal). (shrink)

For some time now, the study of cognitive development has been far and away the most active discipline within developmental psychology. Although there would be much disagreement as to the exact proportion of papers published in develop mental journals that could be considered cognitive, 50% seems like a conservative estimate. Hence, a series of scholarly books devoted to work in cognitive devel opment is especially appropriate at this time. The Springer Series in Cognitive Development contains two basic types of books, (...) namely, edited collections of original chapters by several authors, and original volumes written by one author or a small group of authors. The flagship for the Springer Series is a serial publication of the "advances" type, carrying the subtitle Progress in Cognitive Development Research. Each volume in the Progress sequence is strongly thematic, in that it is limited to some well-defined domain of cognitive developmental research (e.g., logical and mathematical development, development of learning). All Progress volumes will be edited collections. Editors of such collections, upon consultation with the Series Editor, may elect to have their books published either as contributions to the Progress sequence or as separate volumes. All books written by one author or a small group of authors are being published as separate volumes within the series. (shrink)

Person‐specific evidence was developed as a grounded theory by analyzing 20 selected case descriptions from interventions using the guided self‐determination method with people with various long‐term health conditions. It explains the mechanisms of mobilizing relational capacity by including person‐specific evidence in shared decision‐making. Person‐specific self‐insight was the first step, achieved as individuals completed reflection sheets enabling them to clarify their personal values and identify actions or omissions related to self‐management challenges. This step paved the way for sharing these insights and (...) challenges in a relationship with a supportive health professional, who could then rely on person‐specific evidence instead of assumptions or a narrow disease perspective for shared decision‐making. Trust in the evidence encouraged the supportive health professional to transfer it to the interdisciplinary team. Person‐specific evidence then enhanced the ability of team members to apply general evidence in a meaningful way. The increased openness achieved by individuals through these steps enabled them to eventually share their new self‐insights in daily life with other people, decreasing loneliness they experienced in self‐management. Relational capacity, the core of the theory, is mobilized in both people with long‐term health conditions and healthcare professionals. Further research on person‐specific evidence and relational capacity in healthcare is recommended. (shrink)