Despite the exponential progress in computing power of digital computers, the development of lifelike cognitive systems appears has not yet reached the complexity of the simplest kinds of organisms. This may be explained by the lack of robustness of digital computers due to the requirements of structural programmability in the conventional computing architectures. In contrast, biological systems appear to operate in a different mode of information processing. In order to approach more lifelike artificial cognitive systems, the integration of natural and (...) unnatural systems may open a path to investigate the possibilities of the desired biological functions such as through the creation of hybrid architectures that interface nature's computing brains with artificial devices such as using the behaviour of the slime mould Physarum polycephalum to influence the behaviour of a mechanical robot. (shrink)