The paper presents an argument for treating certain types of computer simulation as having the same epistemic status as experimental measurement. While this may seem a rather counterintuitive view it becomes less so when one looks carefully at the role that models play in experimental activity, particularly measurement. I begin by discussing how models function as “measuring instruments” and go on to examine the ways in which simulation can be said to constitute an experimental activity. By focussing on the connections (...) between models and their various functions, simulation and experiment one can begin to see similarities in the practices associated with each type of activity. Establishing the connections between simulation and particular types of modelling strategies and highlighting the ways in which those strategies are essential features of experimentation allows us to clarify the contexts in which we can legitimately call computer simulation a form of experimental measurement. (shrink)

The debate between the Mendelians and the (largely Darwinian) biometricians has been referred to by R. A. Fisher as ‘one of the most needless controversies in the history of science’ and by David Hull as ‘an explicable embarrassment’. The literature on this topic consists mainly of explaining why the controversy occurred and what factors prevented it from being resolved. Regrettably, little or no mention is made of the issues that figured in its resolution. This paper deals with the latter topic (...) and in doing so reorients the focus of the debate as one between Karl Pearson and R. A. Fisher rather than between the biometricians and the Mendelians. One reason for this reorientation is that Pearson's own work in 1904 and 1909 suggested that Mendelism and biometry could, to some extent, be made compatible, yet he remained steadfast in his rejection of Mendelism. The interesting question then is why Fisher, who was also a proponent of biometric methods, was able to synthesise the two traditions in a way that Pearson either could not or would not. My answer to this question involves an analysis of the ways in which different kinds of assumptions were used in modelling Mendelian populations. I argue that it is these assumptions, which lay behind the statistical techniques of Pearson and Fisher, that can be isolated as the source of Pearson's rejection of Mendelism and Fisher's success in the synthesis. (shrink)

Despite the close connection between the central limit theorem and renormalization group (RG) methods, the latter should be considered fundamentally distinct from the kind of probabilistic framework associated with statistical mechanics, especially the notion of averaging. The mathematics of RG is grounded in dynamical systems theory rather than probability, which raises important issues with respect to the way RG generates explanations of physical phenomena. I explore these differences and show why RG methods should be considered not just calculational tools but (...) the basis for a physical understanding of complex systems in terms of structural properties and relations. (shrink)

This paper is an examination of evidential holism, a prominent position in epistemology and the philosophy of science which claims that experiments only ever confirm or refute entire theories. The position is historically associated with W.V. Quine, and it is at once both popular and notorious, as well as being largely under-described. But even though there’s no univocal statement of what holism is or what it does, philosophers have nevertheless made substantial assumptions about its content and its truth. Moreover they (...) have drawn controversial and important conclusions from these assumptions. In this paper I distinguish three types of evidential holism and argue that the most oft-cited and controversial thesis is entirely unmotivated. The other two theses are much overlooked, but are well-motivated and free from controversial implications. (shrink)

This paper addresses the role of integrity in global leadership. It reviews the philosophy of ethics and suggests that both contractarianism and pluralism are particularly helpful in understanding ethics from a global leadership perspective. It also reviews the challenges to integrity that come through interactions that are both external and internal to the company. Finally, the paper provides helpful suggestions on how global leaders can define appropriate ethical standards for themselves and their organizations.

I will develop a new problem for almost all realist theories of colour. The problem involves fluctuations in our colour experiences that are due to visual noise rather than changes in the objects we are looking at.

Philosophy and Phenomenological Research, Volume 99, Issue 3, Page 720-725, November 2019.

Prandtl's work on the boundary layer theory is an interesting example for illustrating several important issues in philosophy of science such as the relation between theories and models and whether it is possible to distinguish, in a principled way, between pure and applied science. In what follows I discuss several proposals by the symposium participants regarding the interpretation of Prandtl's work and whether it should be characterized as an instance of applied science. My own interpretation of this example (1999) emphasised (...) the degree of autonomy embedded in Prandtl's boundary layer model and the way it became integrated in the larger theoretical context of hydrodynamics. In addition to extending that discussion here I also claim that the characterization of applied science which formed the basis for the symposium does not enable us to successfully distinguish applied science from the general practice of 'applying' basic scientific knowledge in a variety of contexts. (shrink)

This essay studies Moses Galeano, a Jewish scholar with ties to Crete and the Ottoman Sultan’s court, who traveled to the Veneto around 1500. After describing Galeano’s intellectual milieu, it focuses, first, on circumstantial evidence that he transmitted information central to the rise of Renaissance astronomy. Galeano knew of theories that strongly resemble portions of astronomy texts written by Giovanni Battista Amico and Girolamo Fracastoro at Padua a few decades later. He also knew about theories pioneered by the Damascene Ibn (...) al-Shā˙tir that strongly resemble portions of Copernicus’s work. Next, the article turns to concrete evidence showing that Galeano was part of a network of Jewish scholars who did have contact with Christian scholars in Europe. The essay concludes that, while it is impossible to prove that Galeano had direct contact with Copernicus, he most likely had contact with some European astronomer in the Veneto. (shrink)

I Have argued elsewhere, and still believe, that the Phaedo was written before Plato's first journey to Italy, when the strong Pythagorean influences displayed in that dialogue were reaching him through the Pythagorean centres on the Greek mainland, in particular Phleius and Thebes; and that in the Republic and Phaedrus it is possible to trace equally strong Pythagorean influence but different in detail, because Plato had now come into contact with the Pythagoreans who still remained in Italy, particularly Archytas. The (...) most remarkable of these influences from whatever source was the doctrine of the immortality and transmigration of the soul, which we know to have been held by the earliest Pythagorean society, and the account of the soul's experience in the world below. (shrink)

This article is an attempt to expound and distinguish\nbrentano's concept of "Intentional inexistence" (found in\n'psychologie von einem empirischen standpunkt') and\nhusserl's early concept of intentionality (in 'logische\nuntersuchungen'). The main purpose is to show that\nhusserl's phenomenological views are very different from\nand far more developed than brentano's and that he rejects\nmany of his concepts and doctrines. First, brentano's\ndesignation of eight defining characteristics of mental\nphenomena, the purpose of which is to define psychology, is\noutlined. This is followed by a detailed discussion of\nhusserl's criticisms and revisions, (...) emphasizing what\nhusserl thought was brentano's most important insight,\ni.E., That consciousness is intentional. A discussion of\nthree views of the nature of consciousness is given,\nconcluding with husserl's general criticisms that brentano\nfell victim to dualism and representationalism and that his\nconcept of the intentional nature of mind was distorted by\na commitment to naturalism, the latter being overcome only\nby husserl's own transcendental phenomenology in 'ideen'\nand later works. (shrink)

Volume 20, Issue 3, March 2020, Page 63-65.

New technologies are transforming and reconfiguring the boundaries between patients, research participants and consumers, between research and clinical practice, and between public and private domains. From personalised medicine to big data and social media, these platforms facilitate new kinds of interactions, challenge longstanding understandings of privacy and consent, and raise fundamental questions about how the translational patient pathway should be organised.This editorial introduces the cross-journal article collection "Translation in healthcare: ethical, legal, and social implications", briefly outlining the genesis of the (...) collection in the 2015 Translation in healthcare conference in Oxford, UK and providing an introduction to the contemporary ethical challenges of translational research in biology and medicine accompanied by a summary of the papers included in this collection. (shrink)

The ideas of John McDowell concerning the relations between mind, world and language are brought into contact with those of Julius Kovesi, with a view to seeing whether the latter can illuminate and flesh out the former. McDowell’s dialectic in Mind and World is expounded and reviewed, hinging on the notion of ‘conceptual second nature’ as his suggested way of showing that there is nothing mysteriously non–natural in human animals learning to find their way about both in a world characterised (...) by lawlike connections and in one characterised by rational connections. Kovesi’s redrawing, in Moral Notions, of the Aristotelian material/formal metaphysical distinction as one between the logical elements of concepts, is adduced to show how the world is ‘shot through’ with concepts and reasons: the formal elements of concepts are nothing other than the reasons we have for collecting varied features of the material world under a concept, to meet our bodily and social needs. The mind can then be treated as a set of acquired capacities and dispositions to become conversant with these features and with the corresponding needs. Some possible objections to this bringing together of the two sets of ideas are briefly examined, and overall conclusions drawn. (shrink)

Theory of health care ethics -- Principles of health care ethics -- The moral status of gametes and embryos : storage and surrogacy -- The ethical challenges of the new reproductive technology -- Ethics and aging in America -- -- Healthcare ethics committees : roles, memberships, structure, and difficulties -- Ethics in the management of health information systems -- Technological advances in health care : blessing or ethics nightmare? -- Ethics and safe patient handling and mobility -- Spirituality and healthcare (...) organizations -- A new era of health care : the ethics of healthcare reform -- Health inequalities and health inequities -- The ethics of epidemics -- Ethics of disasters : planning and response -- Domestic violence : changing theory, changing practice -- Looking toward the future. (shrink)

Antidoping policy regulates and punishes the use of substances that are listed on a Prohibited List (PL). These substances are colloquially known as ‘performance-enhancing substances’. There is very little empirical evidence of enhancement for most of the substances on the PL raising the possibility that the perceived enhancement of performance experienced by an athlete is a placebo effect. A placebo effect is a response to an inert substance that is strongly influenced by psychological and social cues in the surrounding environment. (...) It is our contention that, given the lack of proper empirical testing of the substances on the PL, it is in fact the appearance of a substance on the PL that has the strongest performance-enhancing effect in elite athletes. This disconnect between science and WADA’s code raises the question of what we really object to: real performance enhancement achieved using substances on the PL or performance enhancement that occurs because WADA has told us that the substance will enhance performance by placing it on the PL? In this case, antidoping policy would punish those who believe the performance-enhancing myth at the heart of the PL thus leading to a deeply flawed policy that creates its own victims. (shrink)

Working in healthcare can be fulfilling, meaningful, and sometimes exhausting. Creative endeavors may be one way to foster personal resilience in healthcare providers. In this article, we describe an annual arts and humanities program, the Ludwig Rounds, developed at a large academic children’s hospital. The event encourages staff to reflect on resilience by sharing their creative work and how it had an impact on their clinical careers. The multidisciplinary forum also allows staff to connect and learn about each other. We (...) discuss the development of the program, its format and logistics, and lessons learned over the past 15 years. (shrink)

Abstract.Altruism, defined here as a regard for or devotion to the interest of others with whom we are interrelated, is pitted against two other dispositions in human beings: nepotism and egoism. We propose that to become fully human is to become more altruistic. We describe how altruism is mediated by our physiology, is expressed in our psychological development, is evolving in our social institutions, and becomes the moral communities that enforce our sense of right and wrong. A change in any (...) one of these influences changes our disposition—changes who we are and what we do—potentially making altruism more possible in the world. (shrink)

The music learning environment is a context in which fundamental forces and values underlying human musicality may be evident. Social bonding within music-making groups is characterized by a high degree of complexity whereas issues of clarity, accuracy, and coordination remain the focus of learning. Physical and cognitive impairments that compromise music learning opportunities offer a critical test of music's link to social bonding.

Background: Families and clinicians must often weigh competing priorities when making medical decisions for a pediatric patient at the end of life. Few empirical data exist regarding the importance that clinicians place on varying priorities and whether clinical practice conforms to decision-making standards discussed in the literature. Methods: We administered a discrete choice experiment to understand the relative importance of nine pediatric end-of-life decision-making priorities using responses from 364 nurses and physicians from three intensive care units (ICUs) (pediatric ICU, pediatric (...) cardiothoracic ICU, neonatal ICU) in a large children's hospital, with a 54% response rate. We used latent class analysis to characterize subgroups of health professionals based on their patterns of importance for the nine attributes and examined differences in class membership using multinomial logistic regression. Results: Eighty-two percent of respondents were nurses, consistent with the proportion of nurse and physician staff in the units. Latent class analysis separated our sample of health professionals into five distinct classes. All five groups rated the child's comfort and the best interests as most important but differed regarding how they valued other considerations: Group 1 rated highly consideration of the entire family and medical judgment; Group 2, the entire family's interests, parents’ preferences, and religious beliefs; Group 3, maintaining harmony between parents and medical team; Group 4, responsible use of medical resources; and Group 5, medical evidence and prolonging the child's life. Those with more years of experience were less likely to fall in Group 5 (medical evidence/life-prolonging). Profession was not associated with group membership. Conclusions: Nurses and physicians who care for dying children prioritize foremost the child's best interests and comfort but then possess varying secondary priorities about what is most important when making medical decisions. Pediatric palliative care and ethics consultative services should be aware of and prepared to address these differing concerns. (shrink)