Results for 'Shamik Mascharak'

27 found
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  1.  73
    Human Germline CRISPR-Cas Modification: Toward a Regulatory Framework.Niklaus H. Evitt, Shamik Mascharak & Russ B. Altman - 2015 - American Journal of Bioethics 15 (12):25-29.
    CRISPR germline editing therapies hold unprecedented potential to eradicate hereditary disorders. However, the prospect of altering the human germline has sparked a debate over the safety, efficacy, and morality of CGETs, triggering a funding moratorium by the NIH. There is an urgent need for practical paths for the evaluation of these capabilities. We propose a model regulatory framework for CGET research, clinical development, and distribution. Our model takes advantage of existing legal and regulatory institutions but adds elevated scrutiny at each (...)
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  2.  30
    Response to Open Peer Commentaries on “Human Germline CRISPR-Cas Modification: Toward a Regulatory Framework”.Niklaus H. Evitt, Shamik Mascharak & Russ B. Altman - 2016 - American Journal of Bioethics 16 (10):1-2.
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  3. The Possibility of Physicalism.Shamik Dasgupta - 2014 - Journal of Philosophy 111 (9-10):557-592.
    It has been suggested that many philosophical theses—physicalism, normative naturalism, phenomenalism, and so on—should be understood in terms of ground. Against this, Ted Sider (2011) has argued that ground is ill-suited for this purpose. Here I develop Sider’s objection and offer a response. In doing so I develop a view about the role of ground in philosophy, and about the content of these distinctively philosophical theses.
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  4. Metaphysical Rationalism.Shamik Dasgupta - 2016 - Noûs 50 (2):379-418.
    The Principle of Sufficient Reason states that everything has an explanation. But different notions of explanation yield different versions of this principle. Here a version is formulated in terms of the notion of a “grounding” explanation. Its consequences are then explored, with particular emphasis on the fact that it implies necessitarianism, the view that every truth is necessarily true. Finally, the principle is defended from a number of objections, including objections to necessitarianism. The result is a defense of a “rationalist” (...)
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  5. On the Plurality of Grounds.Shamik Dasgupta - 2014 - Philosophers' Imprint 14.
    This paper argues that ground is irreducibly plural: a group of facts can be grounded together, as a collective, even though no member of the group has a ground on its own. This kind of plural grounding is applied to the metaphysics of individuals and quantities, yielding a “structuralist” view in each case. Some more general implications of plural grounding are also discussed.
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  6. Individuals: An Essay in Revisionary Metaphysics.Shamik Dasgupta - 2009 - Philosophical Studies 145 (1):35-67.
    We naturally think of the material world as being populated by a large number of individuals . These are things, such as my laptop and the particles that compose it, that we describe as being propertied and related in various ways when we describe the material world around us. In this paper I argue that, fundamentally speaking at least, there are no such things as material individuals. I then propose and defend an individual-less view of the material world I call (...)
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  7. Symmetry as an Epistemic Notion.Shamik Dasgupta - 2016 - British Journal for the Philosophy of Science 67 (3):837-878.
    Symmetries in physics are a guide to reality. That much is well known. But what is less well known is why symmetry is a guide to reality. What justifies inferences that draw conclusions about reality from premises about symmetries? I argue that answering this question reveals that symmetry is an epistemic notion twice over. First, these inferences must proceed via epistemic lemmas: premises about symmetries in the first instance justify epistemic lemmas about our powers of detection, and only from those (...)
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  8. Constitutive Explanation.Shamik Dasgupta - 2017 - Philosophical Issues 27 (1):74-97.
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  9. Realism and the Absence of Value.Shamik Dasgupta - 2018 - Philosophical Review 127 (3):279-322.
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  10. Absolutism Vs Comparativism About Quantity.Shamik Dasgupta - 2013 - Oxford Studies in Metaphysics 8:105-150.
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  11. Essentialism and the Nonidentity Problem.Shamik Dasgupta - 2018 - Philosophy and Phenomenological Research 96 (3):540-570.
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  12. XV—Normative Non-Naturalism and the Problem of Authority.Shamik Dasgupta - 2017 - Proceedings of the Aristotelian Society 117 (3):297-319.
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  13. Inexpressible Ignorance.Shamik Dasgupta - 2015 - Philosophical Review 124 (4):441-480.
    Sometimes, ignorance is inexpressible. Lewis recognized this when he argued, in “Ramseyan Humility,” that we cannot know which property occupies which causal role. This peculiar state of ignorance arises in a number of other domains too, including ignorance about our position in space and the identities of individuals. In these cases, one does not know something, and yet one cannot give voice to one's ignorance in a certain way. But what does the ignorance in these cases consist in? This essay (...)
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  14. Substantivalism Vs Relationalism About Space in Classical Physics.Shamik Dasgupta - 2015 - Philosophy Compass 10 (9):601-624.
    Substantivalism is the view that space exists in addition to any material bodies situated within it. Relationalism is the opposing view that there is no such thing as space; there are just material bodies, spatially related to one another. This paper assesses this issue in the context of classical physics. It starts by describing the bucket argument for substantivalism. It then turns to anti-substantivalist arguments, including Leibniz's classic arguments and their contemporary reincarnation under the guise of ‘symmetry’. It argues that (...)
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  15. The Bare Necessities.Shamik Dasgupta - 2011 - Philosophical Perspectives 25 (1):115-160.
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  16. Privilege in the Construction Industry.Shamik Dasgupta - 2019 - Philosophy and Phenomenological Research 98 (2):489-496.
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  17. Fictional Characters and Their Discontents: Prolegomena to Any Future Metaphysics of Fictional Entities.Shamik Chakravarty - 2021 - Dissertation, Lingnan University
    In recent metaphysics, the questions of whether fictional entities exist, what their nature is, and how to explain truths of statements such as “Sherlock Holmes lives at 221B Baker Street” and “Holmes was created by Arthur Conan Doyle” have been subject to much debate. The main aim of my thesis is to wrestle with key proponents of the abstractionist view that fictional entities are abstract objects that exist (van Inwagen 1977, 2018, Thomasson 1999 and Salmon 1998) as well as Walton’s (...)
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  18.  12
    Dasgupta, Shamik 123 N5 Davidson, Donald 219, 219 N10, 223, 225-6, 244 N12.Peter Achinstein - 2012 - In Fabrice Correia & Benjamin Schnieder (eds.), Metaphysical Grounding: Understanding the Structure of Reality. Cambridge University Press. pp. 306.
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  19.  37
    Teaching and Learning Guide For: Substantivalism Vs Relationalism About Space in Classical Physics.Shamik Dasgupta - 2015 - Philosophy Compass 10 (10):736-737.
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  20.  15
    Current Controversies in Philosophy of Science.Shamik Dasgupta, Brad Weslake & Ravit Dotan (eds.) - 2020 - London: Routledge.
    _Current Controversies in Philosophy of Science_ asks twelve philosophers to debate six questions that are driving contemporary work in this area of philosophy. But each question also leads readers back to more general issues and shows how these general issues play out in contemporary debates. The result is a book that’s perfect for the advanced student, building up her knowledge of the foundations of the field while also engaging with its cutting-edge questions. Preliminary descriptions of each chapter, annotated bibliographies for (...)
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  21. Is There Reason to Believe the Principle of Sufficient Reason?Jordan David Thomas Walters - 2021 - Philosophia 50 (2):1-10.
    Shamik Dasgupta (2016) proposes to tame the Principle of Sufficient Reason (PSR) to apply to only non-autonomous facts, which are facts that are apt for explanation. Call this strategy to tame the PSR the taming strategy. In a recent paper, Della Rocca (2020a) argues that proponents of the taming strategy, in attempting to formulate a restricted version of the PSR, nevertheless find themselves committed to endorsing a form of radical monism, which, in turn, leads right back to an untamed-PSR. (...)
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  22. Dasgupta's Detonation.Theodore Sider - forthcoming - Philosophical Perspectives.
    Shamik Dasgupta has argued that realists about natural properties (and laws, grounding, etc.) cannot account for their epistemic value. For "properties are cheap": in addition to natural properties and any value the realist might attach to them, there are also "shmatural" properties (standing to natural properties like charge and mass as Goodman's grue and bleen stand to green and blue) and a corresponding "shmvalue" of theorizing in terms of them. Dasgupta's challenge is one of objectivity: the existence of the (...)
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  23. Reading the Book of the World.Thomas Donaldson - 2015 - Philosophical Studies 172 (4):1051-1077.
    In Writing the Book of the World, Ted Sider argues that David Lewis’s distinction between those predicates which are ‘perfectly natural’ and those which are not can be extended so that it applies to words of all semantic types. Just as there are perfectly natural predicates, there may be perfectly natural connectives, operators, singular terms and so on. According to Sider, one of our goals as metaphysicians should be to identify the perfectly natural words. Sider claims that there is a (...)
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  24.  80
    The Structuralist Approach to Underdetermination.Chanwoo Lee - 2022 - Synthese 200 (2):1-25.
    This paper provides an exposition of the structuralist approach to underdetermination, which aims to resolve the underdetermination of theories by identifying their common theoretical structure. Applications of the structuralist approach can be found in many areas of philosophy. I present a schema of the structuralist approach, which conceptually unifies such applications in different subject matters. It is argued that two classic arguments in the literature, Paul Benacerraf’s argument on natural numbers and W. V. O. Quine’s argument for the indeterminacy of (...)
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  25.  61
    Tamers, Deniers, and Me.Michael Della Rocca - 2021 - Philosophical Studies 178 (4):1101-1119.
    This paper critically examines a prominent and perennial strategy—found in thinkers as diverse as Kant and Shamik Dasgupta—of simultaneously embracing the Principle of Sufficient Reason and also limiting it so as to avoid certain apparently negative consequences of an unrestricted PSR. I will argue that this strategy of taming the PSR faces significant challenges and may even be incoherent. And for my purposes, I will enlist a generally derided argument by Leibniz for the PSR which will help us to (...)
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  26.  8
    Oxford Studies in Metaphysics, Volume 8.Karen Bennett & Dean W. Zimmerman (eds.) - 2013 - Oxford University Press.
    Oxford Studies in Metaphysics is dedicated to the timely publication of new work in metaphysics, broadly construed. These volumes provide a forum for the best new work in this flourishing field. They offer a broad view of the subject, featuring not only the traditionally central topics such as existence, identity, modality, time, and causation, but also the rich clusters of metaphysical questions in neighbouring fields, such as philosophy of mind and philosophy of science. This book is the eighth volume in (...)
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  27. Naturalism and Non-Qualitative Properties.Sam Cowling - 2021 - In Luis R. G. Oliveira & Kevin J. Corcoran (eds.), Common Sense Metaphysics: Essays in Honor of Lynne Rudder Baker. Routledge. pp. 209-238.
    Lynne Baker’s case for the incompatibility of naturalism with the first-person perspective raises a range of questions about the relationship between naturalism and the various properties involved in first-person perspectives. After arguing that non-qualitative properties—most notably, haecceities like being Lynne Baker—are ineliminably tied to first-person perspectives, this paper considers whether naturalism and non-qualitative properties are, in fact, compatible. In doing so, the discussion focus on Shamik Dasupgta’s argument against individuals and, in turn, non-qualitative properties. Several strategies for undermining Dasgupta's (...)
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