ABSTRACTTaking some controversial claims philosopher Jason Brennan makes in his book Against Democracy as a starting point, this paper argues in favour of two theses: There is No Such Thing as Superior Political Judgement; There Is No Such Thing as Uncontroversial Social Scientific Knowledge. I conclude that social science experts need to be kept in check, not given more power.

Empirical agreement is often used as an important criterion when assessing the validity of scientific models. However, it is by no means a sufficient criterion as a model can be so adjusted as to fit available data even though it is based on hypotheses whose plausibility is known to be questionable. Our aim in this paper is to investigate into the uses of empirical agreement within the process of model validation.

Perspectivism is often understood as a conception according to which subjective conditions inevitably affect our knowledge and, therefore, we are never confronted with reality and facts but only with interpretations. Hence, subjectivism and anti-realism are usually associated with perspectivism. The thesis of this paper is that, especially in the case of the sciences, perspectivism can be better understood as an appreciation of the cognitive attitude that consists in considering reality only from a certain ‘point of view’, in a way that (...) can avoid subjectivism. Whereas the way of conceiving a notion is strictly subjective, the way of using it is open to intersubjective agreement, based on the practice of operations whose nature is neither mental nor linguistic. Therefore, intersubjectivity is possible within perspectivism. Perspectivism can also help understand the notion of ‘scientific objects’ in a referential sense: they are those ‘things’ that become ‘objects’ of a certain science by being investigated from the ‘point of view’ of that science. They are ‘clipped out’ of things by means of standardized operations which turn out to be the same as those granting intersubjectivity. Therefore this ‘strong’ sense of objectivity, which is clearly realist, coincides with the ‘weak’ one. The notion of truth appears fully legitimate in the case of the sciences, being clearly defined for the regional ontology of each one of them and, since this truth can be extended in an analogical sense to the theories elaborated in each science, it follows that are real also the unobservable entities postulated by those theories. (shrink)

The first part of this book is of an epistemological nature and develops an original theory of scientific objectivity, understood in a weak sense (as intersubjective agreement among the specialists) and a strong sense (as having precise concrete referents). In both cases it relies upon the adoption of operational criteria designed within the particular perspective under which any single science considers reality. The "object" so attained has a proper ontological status, dependent on the specific character of the criteria (...) of reference (regional ontologies). This justifies a form of scientific realism. Such perspectives are also the result of a complex cultural-historical situation. The awareness of such a "historical determinacy" of science justifies including in the philosophy of science the problems of ethics of science, relations of science with metaphysics, and social dimensions of science that overstep the traditional restriction of the philosophy of science to an epistemology of science. It is to this "context" that the second part of the book is devoted. (shrink)

A naturalistic impulse has taken speculative analytic metaphysics in its critical sights. Importantly, the claim that it is desirable or requisite to give metaphysics scientific moorings rests on underlying epistemological assumptions or principles. If the naturalistic impulse toward metaphysics is to be well-founded and its prescriptions to have normative force, those assumptions or principles should be spelled out and justified. In short, advocates of naturalized or scientific metaphysics require epistemic infrastructure. This paper begins to supply it. The author (...) first sketches her conception of suitably naturalized or scientific metaphysics. She then lays out a number of candidate epistemic principles centring around the notion of theoretical constraint. The author offers several arguments for the principles, based on statistical likeliness, agreement, falsity avoidance, and methodological efficiency and inefficiency. Finally, she shows how scientific metaphysics satisfies the epistemic principles and is therefore preferable to its traditional rivals. (shrink)

This article argues, first, that there is plenty of agreement among philosophers on philosophically substantive claims, which fall into three categories: reasons for or against certain views, elementary truths regarding fundamental notions, and highly conditionalized claims. This agreement suggests that there is important philosophical progress. It then argues that although it's easy to list several potential kinds of philosophical progress, it is much harder to determine whether the potential is actual. Then the article attempts to articulate the truth (...) that the deniers of philosophical progress are latching on to. Finally, it comments on the significance of the agreement and progress. (shrink)

Qualitative research carried out within human science must provide justification for its findings. However, the justification of empirical claims concerning human meanings has to be approached in new ways: Quantitative procedures of validation or the use of experimental control are inappropriate. Many researchers have attempted to follow Schutz's ''postulate of adequacy," which lays down as a condition of acceptability of a scientific account of human action that it be understandable by the actor in terms of commonsense interpretation of everyday (...) life. For instance, Harré suggests "validating" descriptions by ensuring that subjects of the research approve them. Against this approach, it is insisted that human science research is essentially an interpersonal process, and that therefore research activities cannot avoid such Goffmanesque features of self-presentation as resistance to being understood and eager acceptance of understanding, which are both pervasive possibilities of all social interaction. Thus, the research participant's agreement or disagreement cannot be taken as evidence as to the adequacy of a qualitative research description or interpretation. (shrink)

This article attempts to find grounds for agreement and tolerance among environmentalists, as well as all persons of good will who are reasonable and scientifically informed. It beguis by taking stock of where we are today in ethics in general, and then hi environmental ethics in particular. What are the major theories, their central ideas, and problems? Is there a way forward? Explained and defended throughout is the thesis that moral pluralism is the best way forward.

For historical epistemology to succeed, it must adopt a defensible set of categories to characterise scientific activity over time. In historically orientated philosophy of science during the twentieth century, the original categories of theory and observation were supplemented or replaced by categories like paradigm, research program and research tradition. Underlying all three proposals was talk about conceptual systems and conceptual structures, attributed to individual scientists or to research communities, however there has been little general agreement on the nature (...) of these structures. Recent experimental research in cognitive science has considerably refined the theory of concepts. Drawing upon the results of that research, philosophers can construct more concrete and empirically defensible representations of conceptual systems. I will suggest that this research supports a modest and useful sense of both normal and revolutionary science, not as epistemological continuities or discontinuities, but as particular patterns of conceptual change. (shrink)

The collaborative ‹Big Science’ approach prevalent in physics during the mid- and late-20th century is becoming more common in the life sciences. Often computationally mediated, these collaborations challenge researchers’ trust practices. Focusing on the visualisations that are often at the heart of this form of scientific practice, the paper proposes that the aesthetic aspects of these visualisations are themselves a way of securing trust. Kant’s account of aesthetic judgements in the Third Critique is drawn upon in order to show (...) that the image-building capability of imagination, and the sensus communis, both of which are integral parts of aesthetic experience, play an important role in building and sustaining community in these forms of science. Kant’s theory shows that the aesthetic appeal of scientific visualisations is not isolated from two other dimensions of the visualisations: the cognitive-epistemic, aesthetic-stylistic and interpersonal dimensions, and that in virtue of these inter-relationships, visualisations contribute to building up the intersubjectively shared framework of agreement which is basic for trust. (shrink)

Methodological norms are seen as rules defining a competitive game, and it is argued that rational recognition-seeking scientists can reach a collective agreement about which specific norms serve better their individual interests, especially if the choice is made `under a veil of ignorance', i.e. , before knowing what theory will be proposed by each scientist. Norms for theory assessment are distinguished from norms for theory choice (or inference rules), and it is argued that pursuit of recognition only affects this (...) second type of rule. An inference rule similar to `eliminative induction' is defended on the basis of such a possible agreement. According to this contractarian approach, both the explanation and the justification of scientific norms only need to refer to the preferences of individual scientists, without assuming the existence of `collective' points of view. (shrink)

Biomedical research is so important that there is a positive moral obligation to pursue it and to participate in itScience is under attack. In Europe, America, and Australasia in particular, scientists are objects of suspicion and are on the defensive.i“Frankenstein science”5–8 is a phrase never far from the lips of those who take exception to some aspect of science or indeed some supposed abuse by scientists. We should not, however, forget the powerful obligation there is to undertake, support, and participate (...) in scientific research, particularly biomedical research, and the powerful moral imperative that underpins these obligations. Now it is more imperative than ever to articulate and explain these obligations and to do so is the subject and the object of this paper.Let me present the question in its starkest form: is there a moral obligation to undertake, support and even to participate in serious scientific research? If there is, does that obligation require not only that beneficial research be undertaken but also that “we”, as individuals and “we” as societies be willing to support and even participate in research where necessary?Thus far the overwhelming answer given to this question has been “no”, and research has almost universally been treated with suspicion and even hostility by the vast majority of all those concerned with the ethics and regulation of research. The so called “precautionary approach”9 sums up this attitude, requiring dangers to be considered more likely and more serious than benefits, and assuming that no sane person would or should participate in research unless they had a pressing personal reason for so doing, or unless they were motivated by a totally impersonal altruism. International agreements and protocols—for example, the Declaration of Helsinki10 and the CIOMS Guidelines11—have been directed principally at …. (shrink)

For decades, cigarette companies helped to promote the impression that there was no scientific consensus concerning the safety of their product. The appearance of controversy, however, was misleading, designed to confuse the public and to protect industry interests. Created scientific controversies emerge when expert communities are in broad agreement but the public perception is one of profound scientific uncertainty and doubt. In the first book-length analysis of the concept of a created scientific controversy, David Harker (...) explores issues including climate change, Creation science, the anti-vaccine movement and genetically modified crops. Drawing on work in cognitive psychology, social epistemology, critical thinking and philosophy of science, he shows readers how to better understand, evaluate, and respond to the appearance of scientific controversy. His book will be a valuable resource for students of philosophy of science, environmental and health sciences, and social and natural sciences. (shrink)

Scientific consensus is widely deferred to in public debates as a social indicator of the existence of knowledge. However, it is far from clear that such deference to consensus is always justified. The existence of agreement in a community of researchers is a contingent fact, and researchers may reach a consensus for all kinds of reasons, such as fighting a common foe or sharing a common bias. Scientific consensus, by itself, does not necessarily indicate the existence of (...) shared knowledge among the members of the consensus community. I address the question of under what conditions it is likely that a consensus is in fact knowledge based. I argue that a consensus is likely to be knowledge based when knowledge is the best explanation of the consensus, and I identify three conditions—social calibration, apparent consilience of evidence, and social diversity, for knowledge being the best explanation of a consensus. (shrink)

Abstract:The Paris Agreement requires that States take action to avoid dangerous climate change. It is informed by the Intergovernmental Panel on Climate Change that summarizes hundreds of scientific articles, yet the language of the treaty does not mirror the scientific literature. Instead, the Agreement encourages States to join in a collective effort without assigning responsibility for past emissions. The Agreement tells a story that does not track the truth. One justification is to see it as (...) a "noble lie," and that, like in the Republic, it could be the story that States need to hear to do what must be done. (shrink)

Any division between scientific practice and a metalevel of the methods and goals of science is largely a false dichotomy. Since a priori, foundationist or logicist approaches to normative principles have proven unequal to the task of representing actual scientific practice, methodologies of science must be abstracted from episodes in the history of science. Of course, it is possible that such characteristics could prove universal and constant across various eras. But, case studies show that they are not in (...) anything beyond the strictures applied to everyday, commonsense reasoning (e.g., a requirement of noncontradiction in a deductive argument). Hence, even if some presently-on-offer methodology or description of past scientific practice were adequate, it need not remain so for current (‘frontier’) areas of science. For this reason, it is important to examine recent episodes in, say, high-energy physics. Results from case studies of several episodes in that field are used to argue that successful practice leads scientists to countenance essential changes in the methodological framework at the levels of the criteria employed in judging theories (i.e., what counts for an explanation and what are canons of rationality) and of the goals of science. *Partial support for this research was provided by the History and Philosophy of Science Program of the National Science Foundation under grants Nos. SES-8606472 and SES-8705469. A preliminary version of this paper was given at an HPS seminar at King's College, London University in May 1988. Helpful comments and useful criticisms were made by several colleagues, especially Ernan McMullin, Heinz Post and Simon Saunders (none of whom are to be held responsible for or necessarily even in agreement with the views expressed here.). (shrink)

The current state of philosophy of science is characterized by stasis in the struggle between realism and antirealism. In recent years, a number of authors have come out with a program of scientific perspectivism that claims to sublate this great collision and gain the status of a new epistemological paradigm: “perspectivism, or, better, perspectival realism, is one of the newest attempts to find a middle ground between scientific realism and antirealism” [1. P. 2]. Important milestones of the perspective (...) movement were the works of Ronald Giere, Francois Recanati, Bas van Fraassen, Michela Massimi, and others. The thesis of the article is that perspectivism has not yet realized its claims to autonomy, although it has become an important new arena for discussions between realists and antirealists who try to appropriate perspectivist concepts and arguments. The “middle ground,” when thought out consistently and thoroughly, turns out to lie not “between,” but either in the territory of realism or in the territory of antirealism, depending on the presumptions of the author of a particular perspectivist conception. This is demonstrated by the analysis of the conceptions of Giere, Massimi, and Recanati. Giere’s perspectivism is based on the metaphor of color vision, and for him only some (secondary) qualities of real objects turn out to be perspectival, i.e., subject-dependent. Massimi’s perspectivism attempts, on the basis of a visual arts metaphor, to combine the phenomenon of the plurality of scientific theories (“perspectival disagreement” about what an object is) with the general realist attitude of science (agreement about that there is an object). Recanati’s perspectivism syncretizes realism about ordinary objects and relativism about other things. The first two versions of perspectivism rely on a perceptual metaphor: perspective is conditioned by the perceptual constitution of the observer, that is, it arises at the mental or cognitive level. Recanati’s version attempts to derive perspective from contextuality, that is, it is semantic. However, it does not show exactly how perceptual categories are superimposed on theories or how scientific concepts reveal their perspectival character. The isomorphism of perception and theoretical thinking, sensibility and understanding, remains undemonstrated. On the one hand, perspectivist efforts are motivated by an important concern to account for antirealist critique (lack of access to the “view from nowhere,” factual and semantic underdetermination, difficulties with the idea of approaching the truth, the historicity of knowledge, the activeness of the constructing subject, etc.) while preserving the scientific commitment to universality, validity, and truthfulness. On the other hand, the ontological question remains fundamental and unavoidable, and perspectivism (yet?) fails to circumvent it. As we see, all three versions of perspectivism considered in this article turn out to be varieties of realism: Giere and Massimi recognize this explicitly, while Recanati de facto assumes a quite respectable and conservative position of selective realism with respect to ordinary objects. (shrink)

The protection of rare species abounds with scientific and ethical considerations. An ethical dilemma can emerge when the life of one species is valued higher than that of another, and so we discuss the basis of ranking, protection, and valuation of plants and animals. A duty to protect rare species exists in this age of great losses to plant and animal life, but the scientific and public communities are not always in agreement regarding what species deserve protection. (...) Using a case study, we illustrate how the decision to kill beavers to protect a rare plant and rare animals found in a tidewater creek demanded an ecological ethic approach. We present the concept of a" conservation mediator" and how its use may help find a common ground between stakeholders and decision-makers in similar situations. (shrink)

My main topic will be, roughly speaking, the claim that mental events or conscious experiences or inner experiences are brain processes. I hasten to say, however, that I am not going to talk about “mental events” or “conscious experiences” or “inner experiences.” These expressions are almost exclusively philosophers terms, and I am not sure that I have got the hang of any of them. Philosophers are not in agreement in their use of these terms. One philosopher will say, for (...) example, that a pain in the foot is a mental event, whereas another will say that a pain in the foot certainly is not a mental event. (shrink)

An international legal agreement governing the global antimicrobial commons would represent the strongest commitment mechanism for achieving collective action on antimicrobial resistance (AMR). Since AMR has important similarities to climate change—both are common pool resource challenges that require massive, long-term political commitments—the first article in this special issue draws lessons from various climate agreements that could be applicable for developing a grand bargain on AMR. We consider the similarities and differences between the Paris Climate Agreement and current governance (...) structures for AMR, and identify the merits and challenges associated with different international forums for developing a long-term international agreement on AMR. To be effective, fair, and feasible, an enduring legal agreement on AMR will require a combination of universal, differentiated, and individualized requirements, nationally determined contributions that are regularly reviewed and ratcheted up in level of ambition, a regular independent scientific stocktake to support evidence informed policymaking, and a concrete global goal to rally support. (shrink)

Attempts by 20th century philosophers of science to define inductive concepts and methods concerning the support provided to scientific theories by empirical data have been unsuccessful. Although 20th century philosophers of science largely ignored statistical methods for testing theories, when they did address them they argued against rather than for their use. In contrast, this study demonstrates that traditional statistical methods used for validating computer simulation models provide tests of the scientific theories that those models may embody. This (...) study shows that these statistical methods are applicable regardless of whether the scientific theory or model is deterministic, stochastic, or chaos-based in nature. Traditional statistical methods, such as hypothesis testing, test theories by providing measures of their goodness-of-fit with the portion of the world the theories describe. Nothing more is needed to portray the agreement between theory and the world. Furthermore, the statistical measures of goodness-of-fit are not ampliative inductive measures. Therefore, the ultimate value and direction of the 20 th century ampliative inductive program within philosophy of science is thrown into question. This study also suggests that advanced statistical, visualization, and hybrid quantitative qualitative methods hold promise for offering scientists additional methods for testing scientific theories through validating their computer model representations. As a prerequisite to the above discussions, this study proves that scientific theories, when applied to concrete physical systems, can indeed be represented by computer models. (shrink)

Among systems of normative ethics, Utilitarianism has been the one most persistently claimed to stand on a scientific basis. The paper restates this claim by showing that although Mill’s so-called "proof"of Utilitarianism is indefensible even in terms of non-demonstrative plausibility, an alternative argument can be constructed yielding the same conclusion by making use of a "minimum agreement principle". It is argued, further, that the concept of happiness central to Utilitarianism is empirically determinate and is capable of scientific (...) investigation by various psychological and sociological approaches. (shrink)

Although Kuhn, Lakatos and Laudan disagree on many points, these three widely accepted accounts of scientific growth do agree on certain key features of scientific revolutions. This minimal agreement is sufficient to place stringent restraints on the historical development of science. In particular it follows from the common features of their accounts that scientific history can never repeat. Using the term 'supertheory' to denote indifferently the large scale historical entitites employed in all three accounts, it is (...) shown that a supertheory cannot succeed itself, or reappear after a number of intervening scientific revolutions. The relation of these arguments to the details of the three accounts is briefly examined. (shrink)

A multitude of legislation impacts the use of samples and data for research in South Africa. With the coming into effect of the Protection of Personal Information Act No. 4 of 2013 in July 2021, recent attention has been given to safeguarding research participants’ personal information. The protection of participants’ privacy in research is essential, but it is not the only risk at stake in the use and sharing of personal information. Other rights and interests that must also be considered (...) and safeguarded include the right to non-discrimination, the right to dignity, and the right to enjoy the benefits of scientific progress. This can be achieved by ensuring that the ethical values and universal principles that underpin the research landscape, namely equity, reciprocity, justice and solidarity, are embedded in the regulatory framework for the management and use of personal information. This paper advocates an integrated bioethics approach to the use of personal information for research in SA. A key feature in embedding such an approach is a Data Transfer Agreement that appropriately integrates the safeguards and protections set out by our regulatory framework with bioethical rules and procedures when personal information is used and shared for research purposes. This paper thus calls for the development of a national DTA that is guided by key ethical principles when data are shared for research purposes. This paper will be followed by a webinar on 23 June 2022 hosted by the Department of Science and Innovation and the SA Medical Research Council, where the recommendations and suggestions set out herein will be unpacked, discussed and debated by relevant stakeholders. (shrink)

The present paper is concerned with the question of whether scientific conceptual analysis provides better justification than armchair conceptual analysis. In order to address this question, I provide exact definitions of armchair conceptual analysis and scientific conceptual analysis. Furthermore, I use a certain criticism of armchair conceptual analysis, raised by experimental philosophers, as a basis for an argument to the conclusion that scientific conceptual analysis provides better justification than armchair conceptual analysis, and consider the expertise defence as (...) a possible response to this argument. The argument is based on the idea that the concept of a common usage implies a certain degree of uniformity among different speakers, and can be called ‘argument from uniformity of agreement’. The expertise defence can be understood as an attack of one of the premises of this argument. Finally, I present and discuss the results from an empirical study in which scientific conceptual analysis was used in order to gather evidence as regards the soundness of the argument from uniformity of agreement and the expertise defence. (shrink)

The paper considers the two main challenges to scientific realism, stemming from confirmation holism and the underdetermination thesis as well as from semantic holism and the incommensurability thesis. Against the first challenge, it is argued that there are other criteria besides agreement with experience that enable a rational evaluation of competing theories. Against the second challenge, it is argued that at most a thesis of local incommensurability can be defended that is compatible with a minimal version of (...) class='Hi'>scientific realism, namely conjectural realism. However, in order to establish a fully-fledged scientific realism, one has to refute the local incommensurability thesis as well, showing how a comparison is possible on the level of the proper concepts of the theories in question. The paper examines the prospects for such a comparison, distinguishing three cases. (shrink)

Discussions of objectivity often start from considerations about disagreement. We might ask why this should be so. It makes it seem as though disagreement were surprising, but there is no reason why that should be so (the earliest thinkers in the Western tradition found conflict at least as obvious a feature of the world as concord). The interest in disagreement comes about, rather, because neither agreement nor disagreement is universal. It is not that disagreement needs explanation and agreement (...) does not, but that in different contexts disagreement requires different sorts of explanation, and so does agreement. (shrink)

Concerns about the risks of unmitigated greenhouse gas emissions are growing. At the same time, confidence that international policy agreements will succeed in considerably lowering anthropogenic greenhouse gas emissions is declining. Perhaps as a result, various geoengineering solutions are gaining attention and credibility as a way to manage climate change. Serious consideration is currently being given to proposals to cool the planet through solar-radiation management. Here we analyze how the unique and nontrivial risks of geoengineering strategies pose fundamental questions at (...) the interface between science and ethics. To illustrate the importance of integrated ethical and scientific analysis, we define key open questions and outline a coupled scientific-ethical research agenda to analyze solar-radiation management geoengineering proposals. We identify nine key fields of coupled research including whether solar-radiation management can be tested, how quickly learning could occur, normative decisions embedded in how different climate trajectories are valued, and justice issues regarding distribution of the harms and benefits of geoengineering. To ensure that ethical analyses are coupled with scientific analyses of this form of geoengineering, we advocate that funding agencies recognize the essential nature of this coupled research by establishing an Ethical, Legal, and Social Implications program for solar-radiation management. (shrink)

Discussions of objectivity often start from considerations about disagreement. We might ask why this should be so. It makes it seem as though disagreement were surprising, but there is no reason why that should be so (the earliest thinkers in the Western tradition found conflict at least as obvious a feature of the world as concord). The interest in disagreement comes about, rather, because neither agreement nor disagreement is universal. It is not that disagreement needs explanation and agreement (...) does not, but that in different contexts disagreement requires different sorts of explanation, and so does agreement. (shrink)

: This paper contains the analysis of nine interviews with UK scientists on the topic of scientific models. Scientific models are an important, very controversially discussed topic in philosophy of science. A reasonable expectation is that philosophical conceptions of models ought to be in agreement with scientific practice. Questioning practicing scientists on their use of and views on models provides material against which philosophical positions can be measured.

Johnson and Stricker published an opinion piece in the Journal of Medical Ethics presenting their perspective on the 2008 agreement between the Infectious Diseases Society of America (IDSA) and the Connecticut Attorney General with regard to the 2006 IDSA treatment guideline for Lyme disease. Their writings indicate that these authors hold unconventional views of a relatively common tick-transmitted bacterial infection caused by the spirochete Borrelia burgdorferi. Therefore, it should come as no surprise that their opinions would clash with the (...) IDSA's evidence-based guidelines for the diagnosis and treatment of Lyme disease. Their allegations of conflict of interest against the IDSA resemble those made against the National Institutes of Health, the Food and Drug Administration and the Centers for Disease Control and Prevention in 2000, which were found to be baseless. It is the responsibility of all physicians and medical scientists to stand up to antiscientific, baseless and unethical attacks on those who support an evidence-based approach to caring for patients. (shrink)

"In preparing this remarkable book, Ernest Hook persuaded an eminent group of scientists, historians, sociologists and philosophers to focus on the problem: why are some discoveries rejected at a particular time but later seen to be valid? The interaction of these experts did not produce agreement on 'prematurity' in science but something more valuable: a collection of fascinating papers, many of them based on new research and analysis, which sometimes forced the author to revise a previously-held opinion. The book (...) should be enthusiastically welcomed by all readers who are interested in how science works."—Stephen G. Brush, co-author of Physics, The Human Adventure: From copernicus to Einstein and Beyond "Prematurity and Scientific Discovery contains interesting and insightful papers by numerous well-known scientists and scholars. It will be of wide interest, not only to science studies scholars but also to working scientists and to science-literate general readers."—Thomas Nickles, editor of Scientific Discovery, Logic, and Rationality. (shrink)

Good chefs know the importance of maintaining sharp knives in the kitchen. What’s their secret? A well-worn Taoist allegory offers some advice. The king asks about his butcher’s impressive knifework. “Ordinary butchers,” he replied “hack their way through the animal. Thus their knife always needs sharpening. My father taught me the Taoist way. I merely lay the knife by the natural openings and let it find its own way through. Thus it never needs sharpening” (Kahn 1995, vii; see also Watson (...) 2003, 46). Plato famously employed this image as an analogy for the reality of his Forms (Phaedrus, 265e). Just like an animal, the world comes pre-divided for us. Ideally, our best theories will be those which “carve nature at its joints”. While Plato employed the “carving” metaphor to convey his views about the reality of his celebrated Forms, its most common contemporary use involves the success of science -- particularly, its success in identifying distinct kinds of things. Scientists often report discovering new kinds of things -- a new species of mammal or novel kind of fundamental particle, for example -- or uncovering more information about already familiar kinds. Moreover, we often notice considerable overlap in different approaches to classification. As Ernst Mayr put it: No naturalist would question the reality of the species he may find in his garden, whether it is a catbird, chickadee, robin, or starling. And the same is true for trees or flowering plants. Species at a given locality are almost invariably separated from each other by a distinct gap. Nothing convinced me so fully of the reality of species as the observation . . . that the Stone Age natives in the mountains of New Guinea recognize as species exactly the same entities of nature as a western scientist. (Mayr 1987, 146) Such agreement is certainly suggestive. It suggests that taxonomies are discoveries rather than mere inventions. Couple this with their utility in scientific inference and explanation and we have compelling reason for accepting the objective, independent reality of many different natural kinds of things.. (shrink)

The Crimea Conference is by all means an extremely complex historical event. Any attempt to estimate its role and significance without analyzing its ethical components would unavoidably result in unduly simplifying the historical reality of the time, as well as in forming erroneous assumptions that would necessarily be used in the analysis of the causes of Cold War. A thorough examination will show that as far as the ‘ethical’ issues are concerned, there are significant developments with regard to general methodology, (...) as well as its application to the sources. Generations of historians who have addressed the issue of Yalta Conference, although they have not been able to form a scientific, distinct ‘ethical’ tradition so far, have developed all the necessary prerequisites for its establishment. This is evident in the possibility of segmenting the issue in two parts on the one hand, and on the other in the availability of sufficient sources, structured databases, and selected outstanding works. Still, there are no studies about the Yalta Conference so far that address exclusively ethical issues concerning ‘good’ and ‘evil,’ ‘morality,’ ‘duty,’ and ‘honor.’ Although historiographical approaches are to a large extent dependent upon ethical viewpoints, in the case of Yalta agreements so far there have been no techniques available, so as to connect historical accounts with ideology, and historical facts with their philosophical background. In a sense, the situation is quite the same as it is with the study of prehistory: although there is an abundance of data and facts that can be primarily processed, there are no methodological guidelines, nor any devices to classify and explain them. This is also typical for any question raised about the ethics of the Yalta agreements in February 1945. (shrink)

Clinical Study Agreements can have profound effects both on the protection of human subjects and on the independence of investigators to conduct research with scientific integrity. Sponsors, institutions, and even investigators may fail to give adequate attention to these issues in the negotiation of CSAs. Despite the key role of CSAs in structuring ethically important aspects of research, they remain largely unregulated and unreviewed for adherence to ethical norms. Academic institutions routinely enter into research contracts that fail to meet (...) adequate ethical standards. This is a failing that can have serious consequences.Accordingly, it is necessary that some independent body have the authority both to review research contracts for compliance with norms of subject protection and ethical integrity, and to reject studies that fail to meet ethical standards. Such review should take place prior to the start of research, not later. Because of its expertise and authority, the institutional ethics review board is the appropriate body to undertake such review. Much recent commentary has focused on contractual restrictions on the investigator’s freedom to publish research findings. The Olivieri experience, and that of other investigators, has brought freedom of publication issues into sharp focus. Clinical study agreements also raise a number of other ethical issues relating to human subjects and research integrity, however, including disclosures relating to patient safety, data analysis and reporting, budget, confidentiality, and premature termination of the study. This paper describes the ethical issues at stake in structuring such agreements and suggests ethical standards to guide institutional ethics review. (shrink)

Do physicists believe that general relativity is true, and that electrons and phonons exist, and if so, in what sense? To what extent does the spectrum of positions among physicists correspond to philosophical positions like scientific realism, instrumentalism, or perspectivism? Does agreement with these positions correlate with demographic factors, and are realist physicists more likely to support research projects purely aimed at increasing knowledge? We conducted a questionnaire study to scrutinize the philosophical stances of physicists. We received responses (...) from 384 physicists and 151 philosophers. Our main findings are (1) On average, physicists tend toward scientific realism, and slightly more so than philosophers of science. (2) Physicists can be clustered into five groups. Three show variants of scientific realism, one is instrumentalist, and one seems undecided or incoherent. (3) Agreement with realism weakly correlates with approval of building a bigger particle collider. (4) Agreement with realism weakly correlates with the seniority of physicists. (5) We did not find correlations with other factors, such as whether physicists focus on theoretical or experimental research and whether they engage with applied or basic research. (shrink)

Rl In response to Somit & Peterson's call for multiple journal manuscript submissions, and consistent with Cicchetti (1991a and 1991b), counterarguments are presented. The policy for multiple submissions is difficult to defend scientifically ana would place an unwarranted burden on both reviewers and journal editors. As such the policy is again rejected. R2 As earlier hypothesized, referee agreement on manuscripts submitted to a major journal in chemistry was significantly higher for acceptance than for rejection. This is consistent with the (...) high acceptance rate (>70%) of this journal. There is significantly more referee agreement on rejection than on acceptance for manuscripts submitted to major journals, in behavioral science and medicine. These journals have high rejection rates (often >70%). (shrink)

Our starting point in this article is the debate between John Harris and Iain Brassington on whether or not there is a duty to take part in scientific research. We consider the arguments that have been put forward based on fairness and a duty to rescue, and suggest an alternative justification grounded in a hypothetical agreement: that is, because effective healthcare cannot be taken for granted, but requires continuous medical research, and nobody knows what kind of healthcare they (...) will need, participating in research should be viewed from the perspective of a social contract, based on our mutual need for medical advances. (shrink)

Consensus about a classification is defined as agreement on a set of classes and their relations for us in forming beliefs. While most research on scientific consensus has focused on consensus about a belief as a mark of truth, we highlight the importance of consensus in justifying shared classificatory language. What sort of consensus, if any, is the best basis for communicating and reasoning with scientific classifications? We describe an often-overlooked coordinative role for consensus that leverage (...) class='Hi'>agreement on how to disagree such that actors involved can still achieve one or more shared aims even when they do not agree on shared beliefs or categories. Looking forward, we suggest that investigating structures and methods for coordinative consensus provides an important new direction for research on the epistemic foundations of knowledge organization. (shrink)

Under what conditions is a group of scientists rational? How would rational scientists collectively agree to make their group more effective? What sorts of negotiations would occur among them and under what conditions? What effect would their final agreement have on science and society? These questions have been central to the philosophy of science for the last two decades. In this 2007 book, Husain Sarkar proposes answers to them by building on classical solutions - the skeptical view, two versions (...) of the subjectivist view, the objectivist view, and the view of Hilary Putnam. Although he finds these solutions not completely adequate, Sarkar retrieves what is of value from them and also expropriates the arguments of John Rawls and Amartya Sen, in order to weave a richer, deeper, and more developed theory of group rationality. (shrink)

From ancient Greece to the present, philosophers have variously emphasized either the similarities or the differences between humans and nonhuman animals as a basis for ethical conclusions. Thus animal ethics has traditionally involved both factual claims, usually about animals’ mental states and capacities, and ethical claims about their moral standing. However, even in modern animal ethics the factual claims are often scientifically uninformed, involve broad generalizations about diverse taxonomic groups, and show little agreement about how to resolve the contradictions. (...) Research in cognitive ethology and animal welfare science provides empirical material and a set of emerging methods for testing the plausibility of claims about animal mentation and thus for clarifying the interests and needs of animals. We suggest that progress in animal ethics requires both philosophically informed science to provide an empirically grounded understanding of animals, and scientifically informed philosophy to explore the ethical implications that follow. (shrink)

We provide examples of the extent and nature of environmental and human health problems and show why in the United States prevailing scientific and legal burden of proof requirements usually cannot be met because of the pervasiveness of scientific uncertainty. We also provide examples of how may assumptions, judgments, evaluations, and inferences in scientific methods are value-laden and that when this is not recognized results of studies will appear to be more factual and value-neutral than warranted. Further, (...) we show that there is a "tension" between the use of the 95 percent confidence rule as a normative basis to reduce speculation in scientific knowledge and other public policy and moral concerns embodied by the adoption of a precautionary principle. Finally, although there is no precise agreement regarding what a precautionary principle might entail, we make several recommendations regarding the placement of the burden of proof and the standard of proof that ought to be required in environmental and human health matters. (shrink)

Three types of unification patterns in the history of physics are considered. The paradigmatic example of synthesis is chosen to be Maxwell’s fusion of electricity, magnetism and light. The analysis of Maxwell’s works enables to extract three hallmarks of any successful scientific unification. The hallmarks appear to be crucial since any violation of them inevitably leads to a radical decrease of the unifying theory’s predictive power. It is contended that classical (Maxwell) and modern (Einstein) milestones of physics growth are (...) in good agreement with the rules extracted. However, all the three basic stages of ‘post-modern’ physics – i.e. the electroweak theory of Weinberg and Salam, GUTs and SUSY approach culminating in the superstrings – can be described as violations of the synthesis rules. (shrink)

In the first half of this dissertation, I develop a heuristic methodology for analyzing scientific solutions to the problem of underdetermination. Heuristics are rough-and-ready procedures used by scientists to construct models, design experiments, interpret evidence, etc. But as powerful as they are, heuristics are also error-prone. Therefore, I argue that they key to prudently using a heuristic is the articulation of meta-heuristics---guidelines to the kinds of problems for which a heuristic is well- or ill-suited. Given that heuristics will introduce (...) certain errors into our scientific investigations, I emphasize the importance of a particular category of meta-heuristics involving the search for robust evidence. Robustness is understood to be the epistemic virtue bestowed by agreement amongst multiple modes of determination. The more modes we have at our disposal, and the more these confirm the same result, the more confident can we be that a result is not a mere artifact of some heuristic simplification. Through an analysis of case-studies in the philosophy of biology and clinical trials, I develop a principled method for modeling and evaluating heuristics and robustness claims in a qualitative problem space. The second half of the dissertation deploys the heuristic methodology to address ethical and epistemological issues in the science of clinical trials. To that end, I develop a network model for the problem space of clinical research, capable of representing the various kinds of experiments, epistemic relationships, and ethical justifications intrinsic to the domain. I then apply this model to ongoing research with the antibacterial agent, moxifloxacin, for the treatment of tuberculosis, tracking its development from initially successful and promising in vitro and animal studies to its disappointing and discordant performance across five human efficacy trials. Given this failure to find a robust result with moxifloxacin across animal and human studies, what should researchers now do? While my final analysis of this case does not definitively answer that question, I demonstrate how my methodology, unlike a statistical meta-analysis, helps to clarify the directions for further research. (shrink)