We report the identification of a recurrent, 520-kb 16p12.1 microdeletion associated with childhood developmental delay. The microdeletion was detected in 20 of 11,873 cases compared with 2 of 8,540 controls and replicated in a second series of 22 of 9,254 cases compared with 6 of 6,299 controls. Most deletions were inherited, with carrier parents likely to manifest neuropsychiatric phenotypes compared to non-carrier parents. Probands were more likely to carry an additional large copy-number variant when compared to matched controls. The clinical (...) features of individuals with two mutations were distinct from and/or more severe than those of individuals carrying only the co-occurring mutation. Our data support a two-hit model in which the 16p12.1 microdeletion both predisposes to neuropsychiatric phenotypes as a single event and exacerbates neurodevelopmental phenotypes in association with other large deletions or duplications. Analysis of other microdeletions with variable expressivity indicates that this two-hit model might be more generally applicable to neuropsychiatric disease. © 2010 Nature America, Inc. All rights reserved. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Theology as Interdisciplinary Inquiry: Learning with and from the Natural and Human Sciences eds. by Robin W. Lovin and Joshua MauldinSara A. WilliamsTheology as Interdisciplinary Inquiry: Learning with and from the Natural and Human Sciences Edited by Robin W. Lovin and Joshua Mauldin grand rapids, mi: eerdmans, 2017. 202 pp. $32.00How can Christian theology engage in fruitful dialogue with fields of inquiry such as cognitive science, anthropology, and (...) law? Might discoveries in the natural and human sciences open creative possibilities for theology, and vice versa? Can Christian theology maintain its integrity while integrating insights from other disciplines? Theology as Interdisciplinary Inquiry takes up these questions as its central aim. This volume of six essays emerges from a three-year Templeton Foundation initiative that brought an interdisciplinary set of scholars together at the Center for Theological Inquiry to explore how their research might collaboratively push theology in new directions. These conversations centered on three themes: evolution and human nature, religious experience and moral identity, and law and religious freedom.In the first essay, Celia Deane-Drummond proposes an alternative approach to traditional readings of the Genesis creation account that looks to "resonances" between von Balthasar's notion of "theo-drama" and niche construction theory. Her argument allows for human agency while drawing theology into a complementary, rather than conflictual, relationship with evolutionary science. The next three essays take up the theme of religious experience and moral identity. Michael Spezio proposes that both theology and cognitive science look to moral exemplars as the phenomenological basis for more realistic and mutually informative moral theology and cognitive models of learning. Colleen Shantz draws on cognitive science to demonstrate how the material [End Page 192] and relational are constitutive of cognitive processes, arguing that it is precisely through "development and change" that we bear the imago Dei (66). Andrea Hollingsworth offers a rereading of Nicholas of Cusa's De visione Dei to demonstrate how a medieval mystical text echoes elements of contemporary neurocognitive processes of self-transformation. The final two essays center on law and religious freedom. John Burgess examines the privileging of religious freedom for canonizing martyrs in post-Soviet Russian Orthodoxy, arguing that this provides theological grounding for the legal right to religious freedom. Mary Ellen O'Connell proposes aesthetics as a more adequate modern grounding for legal authority than science. She argues that aesthetics takes us beyond the limits of self-interest, drawing us into concern for the good of others through the contemplation of beauty.What holds these essays together is the pursuit of "transdisciplinarity": "paying close attention to the other discipline(s) in a way that has a substantial and mutual impact, but at the same time retaining a clear sense of disciplinary integrity" (14–15). Lovin and Mauldin argue for humility and hope as virtues that enable us to navigate the tension between openness and integrity. While humility enables us to recognize the limits of disciplinary boundaries and assumptions, hope propels us forward, promising that however incomplete our knowledge remains, by the grace of God we will make advances in understanding our world and ourselves.Just as Christian Scharen and Aana Marie Vigen's Ethnography as Christian Theology and Ethics argues for the value of engagement with ethnography and its related disciplines to produce theology and ethics grounded in lived reality, this volume argues for the value of engagement with the natural and human sciences to produce "theological realism" that accounts for the complexity of "human personality and community" (xviii). It is unsurprising, then, that both volumes respond to objections from the neo-Radical Reformation and Radical Orthodoxy camps. In his conclusion, Douglas Ottati argues that these camps cannot account for the ways in which theological production inevitably interacts with natural and cultural processes. He argues further that insulating Christian theology is a form of cultural accommodation because it mirrors the formation of discrete modern disciplines, the very limitation these essays seek to transcend.This volume advances the live discussion in Christian ethics about the promise and risks of engaging natural and social sciences. It is a valuable resource on this topic, and its essays are suitable for use in seminary course discussions... (shrink)

More and more cities develop urban food strategies to guide their efforts and practices towards more sustainable food systems. An emerging theme shaping these food policy endeavours, especially prominent in North and South America, concerns the enhancement of social justice within food systems. To operationalise this theme in a European urban food governance context we adopt Nancy Fraser’s three-dimensional theory of justice: economic redistribution, cultural recognition and political representation. In this paper, we discuss the findings of an exploratory document analysis (...) of the social justice-oriented ambitions, motivations, current practices and policy trajectories articulated in sixteen European UFSs. We reflect on the food-related resource allocations, value patterns and decision rules these cities propose to alter and the target groups they propose to support, empower or include. Overall, we find that UFSs make little explicit reference to social justice and justice-oriented food concepts, such as food security, food justice, food democracy and food sovereignty. Nevertheless, the identified resources, services and target groups indicate that the three dimensions of Fraser are at the heart of many of the measures described. We argue that implicit, fragmentary and unspecified adoption of social justice in European UFSs is problematic, as it may hold back public consciousness, debate and collective action regarding food system inequalities and may be easily disregarded in policy budgeting, implementation and evaluation trajectories. As a path forward, we present our plans for the RE-ADJUSTool that would enable UFS stakeholders to reflect on how their UFS can incorporate social justice and who to involve in this pursuit. (shrink)

In 2017, British shock-artist Damien Hirst released a coffee-table book with photographs from his Venice Biennale exhibition, Treasures from the Wreck of the Unbelievable, featuring artifacts retrieved from a Roman-era shipwreck in the Indian Ocean. The following year, a “documentary” was released on Netflix featuring the backstory of the wreck's excavation, showing how all those coral-encrusted antiquities made their way from the seafloor to the art scene. At this same time and elsewhere in Britain, a practitioner of art history, art, (...) and maritime archaeology was in the process of developing the concept of “hauntography” as an object-oriented artistic method that represents (visually or otherwise) the ontological absent-presence of shipwrecks, that is, as objects that defy complete phenomenological access, while inspiring speculation into the uncanniness of being a thing of anthropogenic origin, but which persists beyond anthropos. Because both hauntography and Hirst's project make claims regarding epistemological and phenomenological limits pertaining to underwater wreckage, this article answers the question first posed by the author's students as to whether Hirst's satirical take on shipwreck archaeology ought to be considered the first hauntograph. By examining the relationships between two contemporary art projects, underwater archaeology, and object-oriented philosophies, this article considers how art objects might nudge epistemological limits without resorting to a post-truth dismissal of objective reality. (shrink)

This is an exploratory study of corporate social performance in firms with family members in executive, governance, or strong ownership positions. Family firmsdominate the economy in most countries, including the United States, and families are thought to be more concerned with personal wealth creation and risk avoidance than social performance. Although such firms have been shown to have superior financial performance, I found no evidence of superior (or inferior) social performance among family firms in the S&P 500. In a departure (...) from the methodological norm in business and society, I used KLD data as dependent variables instead of independent variables. I was able to predict KLD scores from firm size, industry, and strategy variables, but family firm status rarely played a role. (shrink)

Madole & Harden describe how genetics can be used in a causal framework. We agree with many of their opinions but argue that comparing within-family designs to experiments is unnecessary and that the proposed influence of genetics on behavior can be better described as inus conditions.

In paediatric oncology, research and treatments are often closely combined, which may compromise voluntary informed consent of parents. We identified two key scenarios in which voluntary informed consent for paediatric oncology studies is potentially compromised due to the intertwinement of research and care. The first scenario is inclusion by the treating paediatric oncologist, the second scenario concerns treatments confined to the research context. In this article we examine whether voluntary informed consent of parents for research is compromised in these two (...) scenarios, and if so whether this is also morally problematic. For this, we employ the account of voluntary consent from Nelson and colleagues, who assert that voluntary consent requires substantial freedom from controlling influences. We argue that, in the absence of persuasion or manipulation, inclusion by the treating physician does not compromise voluntariness. However, it may function as a risk factor for controlling influence as it narrows the scope within which parents make decisions. Furthermore, physician appeal to reciprocity is not controlling as it constitutes persuasion. In addition, framing information is a form of informational manipulation and constitutes a controlling influence. In the second scenario, treatments confined to the research context qualify as controlling if the available options are restricted through manipulation of options. Although none of the influences is morally problematic in itself, a combination of influences may create morally problematic instances of involuntary informed consent. Therefore, safeguards should be implemented to establish an optimal environment for parents to provide voluntary informed consent in an integrated research-care context. (shrink)

This qualitative study examines the expectations and beliefs parents, students, and teachers have about the teaching of heritage histories in public high schools. Students from three heritage groups, as well as their parents and teachers, were interviewed to shed light on this complex, often silent, relationship. This study is grounded in literature about the purposes of history education, historical distance, and collective memory/heritage, which give shape to and help to explicate some of the more complex issues inherent in the teaching (...) of heritage histories. Participants included four Hmong students, three of their parents, and their teacher in St. Paul, Minnesota; eight Chinese students, nine of their parents, and their teacher in Elmdale, California; and five Jewish students, five of their parents, and their teacher in Maple Lake, Illinois. Findings indicate that the three stakeholder groups believe that the public school history classroom is an appropriate and desired place for heritage histories to be taught. This is complicated, however, by several factors: the placement of the heritage history narratives within larger curricular and mainstream narratives, how the teachers choose to incorporate the heritage narratives into the formal classroom curriculum, and the changing nature of historical and generational distance. (shrink)

Stakeholder management devices (SMDs) are the mechanisms through which organizations respond to stakeholder concerns. Given that SMDs serve as organizational control systems for employees and managers, this research investigates the internal rather than the external effects of a firm's SMDs. Unlike most previous research, I examined the effects of these formal structures, processes, and procedures in the aggregate, rather than focusing attention on a single type of device. The study investigates the effects of a firm's stakeholder management devices, in the (...) aggregate, on three factors that influence individual behavior in organizations: expectations, attitudes, and perceived organizational climates. Respondents were managers in 112 for-profit businesses located throughout the United States. Results suggest that a firm's stakeholder management devices affect the perceived moral climates in the firm, and affect managers' expectations about the consequences of good corporate social performance, but do not affect organization members' attitudes about corporate social responsibility. (shrink)

A national survey of CEOs of manufacturing firms was conducted to identify factors explaining CEOs' intentions to engage in two questionable business practices: soliciting a competitor's technological secrets and making payments to foreign government officials to secure business. Drawing on research in corporate misconduct, ethical decision making, and strategic management, the authors analyzed ethical intentions by looking at hostile environmental conditions, opportunity-rich situations, and/or personal characteristics. Based on responses to scenarios, their findings suggest that the ethical intentions of CEOs may (...) be more affected by the decision maker's predisposition than by environmental pressures or organizational/situational characteristics. (shrink)

In the current American iconoclash, certain monuments are subject to vandalism and municipal removal from their pedestals. Phrases such as “the erasure of history” and “damnatio memoriae” point to concerns that iconoclasm is an attempt to censor history or even remove certain individuals from public memory altogether. Because these phrases beckon the past, this wave of iconoclasm calls for a close examination of previous image-breaking to establish motives. Drawing first from art history, we analyze Byzantine iconoclasm and anxieties over the (...) nature of icons’ power, before contextualizing these findings within image destruction from the Paleolithic to the present day. Each comparison is suggestive of an enduring aesthetic principle: that what appears inanimate is not always inert. Next, drawing from cultural anthropology, we argue that principles of sympathetic magic are at the heart of contemporary iconoclasms, but not in the way media outlets often suggest. Instead, the fear of history’s erasure betrays a deeply rooted equivalence between the representation and the represented. In perceiving their fates as shared, sympathetic magic is seen to persist in the way humans create, interpret, and desecrate images. We conclude with the speculative realist proposition that iconoclasm can produce new, original artworks, which carries implications for the autonomy of art and its distribution between artist and artwork. (shrink)

Jones (1991) has proposed an issue-contingent model of ethical decision making by individuals in organizations. The distinguishing feature of the issue was identified as its moral intensity, which determines the moral imperative in the situation. In this study, we adapted three scenarios from the literature in order to examine the issue-contingent model. Findings, based on a student sample, suggest that (1) the perceived and actual dimensions of moral intensity often differed; (2) perceived moral intensity variables, in the aggregate, significantly affected (...) an individual''s moral judgments; and (3) some dimensions of moral intensity (namely, perceived social consensus and perceived magnitude of consequences) mattered more than others. (shrink)

This essay explores an increasingly popular genre of organized group travel in white mainline and emerging evangelical US Christianity I call “journeys to the margins”: trips centered on learning from marginalized persons for the traveler’s ethical formation. Drawing on ethnographic research with one case study, “Come and See Tours” to Israel/palestine, I interrogate how the commodified form of these trips shape possibilities for ethical subjectivation. First, I demonstrate ways in which journeys to the margins market ethical transformation to American Christian (...) consumers in the form of packaged moral narratives. Second, I focus on the paradoxical nature of journeys to the margins as simultaneously packaged commodities and ethical encounters. Finally, I use reformulations of freedom emerging from the anthropology of ethics to argue that possibilities for ethical subjectivation occur in moments when tour ideals come into tension with lived realities. (shrink)

Background In the coronavirus disease 2019 era, doctors have tried to decrease hospital visits and admissions. To this end, telemedicine was implemented in a non-systematic manner according. The objective of this study was to assess the current knowledge and attitudes of physicians in Alexandria, Egypt, and Punjab, India, toward telemedicine and its ethical and medico-legal issues. Method A cross-sectional study was implemented using an anonymous self-administered questionnaire carried out over two months (July and August 2020). A four-point Likert scale was (...) used to collect data about background knowledge, training in telemedicine and ethical and medico-legal issues in telemedicine practice. Results The questionnaire was completed by 175 Egyptian and 51 Indian physicians from different specialties. A significantly higher percentage of Indian physicians practiced telemedicine than Egyptian physicians during the coronavirus disease 2019 era. Although most physicians had no specific training or licensing to practice telemedicine, most of them practiced telemedicine through their social media accounts. Ethical violations involving waiving patient consent were detected. Significant ethical violations to doctors, for example, blackmail, defamation, hate speech, accusations in a court and violations of privacy, were observed. Indian physicians (39.2%) and Egyptian physicians (24%) thought the penalties should be lower in telemedicine than in traditional practice. Finally, most participants would like to continue using telemedicine after the coronavirus disease 2019 era but with improvements. Conclusions Coronavirus disease 2019 changed the acceptance of telemedicine by physicians. Many ethical and legal issues need to be addressed and clarified using formal training before implementation and standardization of telemedicine services. (shrink)

Anthropology’s “ethical turn” opens space for dialogue with Christian ethicists engaged in the “ethnographic turn” using a common virtue-inflected language and set of concerns. While moral theologian Michael Banner has called for such a dialogue, there has been a lack of cross-pollination between Banner’s account and the broader ethnographic turn, which has turned to the practice theory of Pierre Bourdieu as its main social scientific interlocuter. In this essay, I argue that the limits of practice theory call for a diversification (...) of social scientific conversation partners in the ethnographic turn. I demonstrate how the anthropology of ethics offers one auspicious way forward in its ability to account for moral agency in everyday life. (shrink)

Although corporate decision makers may justify charitable contributions on strategic grounds, extremely large corporate philanthropic contributions may beperceived by shareholders as unnecessary. If stockholders attempt to limit corporate philanthropy, then governance mechanisms should put a cap on giving amounts. Using a matched-paired sample to control for industry and company size, theauthors compared big givers and small givers. The authors find that blockholders and institutional owners limit corporate philanthropy. This suggests that high levels of corporate philanthropy may be perceived as excessive (...) by influentialstockholders, and some governance mechanisms act to curtail it. (shrink)

This study investigates financial correlates of corporate philanthropy in Fortune 1000 companies using structural equation modeling. The results suggest that cash flow (one of the most discretionary types of organizational slack) has a significant impact on a firm’s cash donations to charitable causes, but monetary donations do not affect firm financial performance. These findings support the accepted view of corporate philanthropy as a discretionary social responsibility and the traditional thinking about firm giving in the business and society literature—that doing well (...) enables doing good. Contrary to some contemporary thinking, the findings imply no significant effect on profits from corporate generosity. (shrink)

This study examines social issues shareholder resolutions filed at S&P 500 companies in 2007. These firms received 86% of all social issues resolutions filed. Findings indicate that green resolutions were the most common single type (30% of social issues resolutions), but nearly one third (32%) of resolutions contained non-traditional content. Firms were more likely to be targeted if they were large in size and demonstrated poor treatment of employees and customers. As might be expected, the primary sponsors of social issues (...) resolutions were socially responsible investment funds, religious groups, and pension funds. Surprisingly, over half (52%) of resolutions made it onto proxy ballots in 2007, while there was sufficient dialogue between the target companies and shareholder activists for filers to withdraw only 29% of the resolutions (although 41% of green resolutions were withdrawn). Resolution content and firm response differed by type of filer. (shrink)

There is increasing evidence to suggest that cytoplasmic tyrosine kinases of the Src family have a pivotal role in the regulation of a number of cellular processes. Members of this family have been implicated in cellular responses to a variety of extracellular signals, such as those arising from growth factors and cell‐cell interactions, as well as in differentiative and developmental processes in both vertebrates and invertebrates. A better understanding of the regulation and of the structure‐function relationships of these enzymes might (...) aid in the development of specific ways to interfere with their action, as well as serving as a paradigm for regulation of other protein tyrosine kinases that have SH2 and SH3 domains. In this review we will first discuss the regulation of Src family protein tyrosine kinases, with particular emphasis on their SH2 and SH3 domains. We will then briefly review other non‐receptor protein tyrosine kinases that have SH2 and SH3 domains. (shrink)

In a departure from the traditional studies of corporate philanthropy that focus on board composition, advertising, and social networks, the authors investigate the financial correlates of corporate philanthropy. The research design controls for firm size and industry while observing firms from a variety of industries. The sample contains matched pairs of generous and less generous corporate givers. The authors find, as hypothesized, a positive relationship between a firm''s cash resources available and cash donations, but no significant relationship between corporate philanthropy (...) and firm financial performance, regardless of whether corporate philanthropy is measured as cash payouts or the aggregate contributions that charities actually receive, and regardless of whether financial performance is gauged using accounting measures or market measures. Whereas the link between available resources and corporate philanthropy is well accepted in the literature on corporate social responsibility, it has been rarely tested and never so definitively found as in this research. (shrink)

We have no interest whatever in minimizing the continuing history of racist, sexist, homophobic, or otherwise abusive biologisms, or the urgency of their exposure, that has made the gravamen of so many contemporary projects of critique. At the same time, we fear — with installation of an automatic antibiologism as the unshifting tenet of `theory' — the loss of conceptual access to an entire thought-realm. I was left wondering what danger had been averted by the exclusion of biology. What does (...) the nominative `biological or anatomical body' actually refer to? And what secures the separation of its inadmissible matter from the proper purview of Irigaray's textual interventions? When I asked a question to this effect it was met with a certain nervous comprehension. Deciding, perhaps, that I must still be immersed in a precritical understanding of the body, the speaker dismissed me with a revealing theatrical gesture. As if to emphasize the sheer absurdity of my question she pinched herself and commented `Well I don't mean this body'. And so it seemed with a gesture so matter of fact that it required no further comment, the fact of matter was both decided and dispatched. Feminism has been as deeply implicated in routinized antiessentialism as any of our critical procedures. Even though questions of `the body' have become increasingly fashionable in all manner of feminist projects, the schedule of feminism's antibiologism has been little altered. In most of these projects on `the body', the body in question is pursued in its socially, experientially, or psychically constituted forms, but rarely in its physiologically, biochemically, or microbiologically constituted form, the idea of biological construction having been rendered either unintelligible or naive. Despite an avowed interest in the body, there is a persistent distaste for biological detail. These feminist theories have usually been reluctant to engage with biological data: they retain, and encourage, the fierce antibiologism that marked the emergence of second wave feminism. That feminist scholars are particularly prone to a `knee jerk constructivism' helps explain the reluctance of those in the humanities to engage seriously with the claims of science. This book functions primarily as a reminder to social, political, and cultural theorists, particularly those interested in feminism, antiracism and questions of the politics of globalisation, that they have forgotten a crucial dimension of research, if not necessary to, then certainly useful for more incisively formulating the concepts on which they so heavily, if implicitly rely. It is written as a remembrance of what we have forgotten — not just the body, but that which makes it possible and which limits its actions: the precarious, accidental, contingent, expedient, striving, dynamic status of life in a messy, complicated, resistant, brute world of materiality, a world regulated by the exigencies, the forces, of space and time. We have forgotten the nature, the ontology, of the body, the conditions under which bodies are encultured, psychologized, given identity, historical location, and agency. We have forgotten where we come from. (shrink)

Although compelling and insightful, the proposal by Uchiyama et al. largely neglects within-person change over time, arguably the central topic of interest within their framework. Longitudinal behavioural genetics modelling suggests that the heritability of trajectories is low, in contrast to high and increasing cross-sectional heritability across development. Better understanding of the mechanisms of trajectories remains a crucial outstanding challenge.

Self-regulation in early childhood is an important predictor of success across a variety of indicators in life, including health, well-being, and earnings. Although conceptually self-regulation has been defined as multifaceted, previous research has not investigated whether there is conceptual and empirical overlap between the factors that comprise self-regulation or if they are distinct. In this study, using a bifactor model, we tested the shared and unique variance among self-regulation constructs and prediction to pre-academic and social-emotional skills. The sample included 932 (...) preschool children, their parents, and their teachers in the United States. Children’s self-regulation was assessed using measures of executive function, behavioral self-regulation, and emotion regulation. The bifactor model demonstrated a common overarching self-regulation factor, as well as distinct executive function and emotion regulation factors. The common overarching self-regulation factor and executive function predicted children’s pre-academic and social-emotional skills. The emotion regulation factor predicted children’s social-emotional skills. Identifying the shared and unique aspects of self-regulation may have important implications for supporting children’s regulatory skills as well as their success in school. (shrink)

Background Families whose child has unexplained intellectual or developmental differences often hope that a genetic diagnosis will lower barriers to community-based therapeutic and support services. However, there is little known about efforts to mobilize genetic information outside the clinic or how socioeconomic disadvantage shapes and constrains outcomes.Methods We conducted an ethnographic study with predominantly socioeconomically disadvantaged families enrolled in a multi-year genomics research study, including clinic observations and in-depth interviews in English and Spanish at multiple time points. Coding and thematic (...) development were used to collaboratively interpret fieldnotes and transcripts.Results Thirty-two families participated. Themes included familial expectations that a genetic diagnosis could be translated into information, understanding, and assistance to improve the quality of a child’s day-to-day life. After sequencing, however, genetic information was not readily converted into improved access to services beyond the clinic, with families often struggling to use a genetic diagnosis to advocate for their child.Conclusion Families’ ability to use a genetic diagnosis as an effective advocacy tool beyond the clinic was limited by the knowledge and resources available to them, and by the eligibility criteria used by therapeutic service providers’ – which focused on clinical diagnosis and functional criteria more than etiologic information. All families undertaking genomic testing, particularly those who are disadvantaged, need additional support to understand the limits and potential benefits of genetic information beyond the clinic. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Whiteness and the General WillDiversity Work as Willful WorkSara AhmedIn this essay I explore whiteness in relation to the general will. My starting point is that the idea of “the general will” offers us a vocabulary for thinking through the materiality of race. In his keynote address to the 40th Annual Philosophy Symposium in 2010, Charles Mills argues that race is material: it becomes part of the living human (...) body. Mills draws on recent theories of whiteness as habit, including the work of Linda Alcoff (2006) and Shannon Sullivan (2006). Quoting from Sullivan, he suggests that whiteness is in “the nose that smells, the back, neck and other muscles that imperceptibly tighten with anxiety, and the eyes that see some but not all physical differences as significant” (Sullivan 2006, 188). Whiteness is embodied; it is in bodily matter as well as affecting how bodies matter. Mills then suggests that the materiality of whiteness is its “resistance to will.” One definition of materiality could be this: resistance to will.This essay takes up the theme of the materiality of race by thinking of whiteness in relation to the will. There are clearly risks in such an undertaking: after all, the idea of whiteness as willed might seem to imply that whiteness is volitional: and can be simply “willed away.”1 I want to suggest that if whiteness is resistant to will, as that which cannot be simply willed away, then whiteness can also be understood as willed: in other words, what cannot be willed away is a willing way. Edward Said’s definition of Orientalism as “willed human work,” which as a definition has yet to be rigorously understood, could be considered an important precedent to my argument (1978, 140). The suggestion is not [End Page 1] simply that the Orient is brought into existence, or made to exist over time, but that the very labor of creating the Orient, the land of the stranger, the land far away, is what establishes a direction. Once the Orient has come to exist, there is a willing of its existence; to keep going that way is to keep that way going. Willed work is work that in willing that way creates a way that can be willed. It is not as the old English cliché says—where there’s a will there’s a way—but rather to will is to way. I think it is useful to think of whiteness in this way, as a willing way, which is of course only one way of thinking about whiteness.I pose the generality of the will as a way of reflecting on “institutional whiteness.” Whiteness becomes “the material” of an institutional body, whether that body is the nation, an organization, a neighborhood, or a street. We can consider an institution as a body with parts: it too has noses, mouths, muscles that register anxiety, as well as ears and eyes. Just think of how Neighborhood Watch, as a national or even global technology, uses the injunction that citizens should become the “eyes and ears of the police.” A good citizen is the one who accepts this injunction: the one who is willing to watch out for strangers, those who are loitering, who seem suspicious, or out of place. Institutions have “detection systems”: they have parts that register the approach of strangers. A collective body in registering those who are out of place, both creates strangers and establishes a direction toward them, as those who threaten the place of the “in place,” as those who generate anxiety.A key event in my own life was of becoming a stranger in a white neighborhood in Adelaide, Australia, in a place I called home. I was fourteen years old. I was stopped by two policemen in a car who asked me, “Are you Aboriginal?” It turned out that there had been some burglaries in the area. It was an extremely hostile address, and it was an unsettling experience at the time. It was an experience of being made into a stranger, the one who is recognized as “out of place,” as the one who does not belong, whose proximity is registered... (shrink)

Attentional control theory suggests that high cognitive demands impair the flexible deployment of attention control in anxious adults, particularly when paired with external threats. Extending this...

This study focusses on discourses on menopause through a critical reading of a selection of nine self-help books on the topic in the context of Dutch-speaking Belgium and the Netherlands. The aim is to explore whether self-help books constrain or facilitate the development of emancipatory discourses on menopause. We combine feminist critiques that identify the experience of menopause as a site of potential for revolt with insights from queer and critical new-materialist theorisation to probe the books’ emancipatory capacity. Our analysis (...) identifies three prominent discursive repertoires: a medical, psycho-therapeutic and spiritual repertoire. Anger and erotic power emerge as important themes, albeit differently framed dependent on the discursive repertoires that the books employ. We conclude that none of the books succeed in disrupting prevailing oppressive discourses that devalue ageing women. There are two important constraints, notably the books’ individualistic and depoliticised stance and their reductionist view on the biological body. As a way out, we propose a gaga feminist reading of menopause that looks at anger and erotic power as sites of ‘biopossibilities’ that may open space for overthrowing oppressive models of gender, sexuality and desire. (shrink)

The global COVID-19 pandemic has created a crisis of suffering. We conceptualize suffering as a deeply existential issue that fundamentally changes people indelible ways and for which there are no easy solutions. To better understand its effects and how people can flourish in the midst of this crisis, we formally introduce and elaborate on an Existential Positive Psychology Model of Suffering (EPPMS) and apply that to the COVID-19 global pandemic. Our model has three core propositions: (a) suffering reveals existential concerns, (...) (b) existential anxiety impairs one's ability to find meaning, and (c) cultivating meaning is the primary way to address suffering and allay existential anxiety, eventually leading to flourishing (and potentially growth). We apply this model to the COVID-19 pandemic, including how to build meaning, and discuss clinical implications. (shrink)

_ Source: _Volume 23, Issue 2, pp 196 - 235 The role of choice in Gersonides’ theory of miracles, as presented in the Wars of the Lord, is discussed. The theory of miracles in Wars vi.2.10 is shown to be another link in his reconciliation of determinism with choice. After a brief review of his ideas about choice, his astral determinism is elucidated. The third part of the essay reviews his treatment of how miracles occur. Gersonides is shown to have (...) established a “conditional miraculous determinism”; his concern for choice is the key to this solution. (shrink)

“Beautiful – do not touch” – this phrase, appearing in a seminar on the ethics of psychoanalysis, is one of the ways in which Jacques Lacan describes the operation in the human psyche of the phantasm principle. It is a construct that I will try to introduce the reader to in this article, describing the direct impact of beauty and the transgression of its principle through the lens of clinical experience. My goal in taking up this “beautiful – do not (...) touch” formula is to show how a concept usually associated with aesthetics has non-obvious but important clinical implications, and even defines a certain ethic of the subject towards sexuality. Another important aspect of this study is the juxtaposition of the problem of beauty with the question of femininity. And not only the one played out through the image, but especially the one that goes beyond representation in the feminine modality of pleasure. (shrink)

ABSTRACTTask-irrelevant emotional expressions are known to capture attention, with the extent of “emotional capture” varying with psychopathic traits in antisocial samples. We investigated whether this variation extends throughout the continuum of psychopathic traits in a community sample. Participants searched for a target face among facial distractors. As predicted, angry and fearful faces interfered with search, indicated by slower reaction times relative to neutral faces. When fear appeared as either target or distractor, diminished emotional capture was seen with increasing affective-interpersonal psychopathic (...) traits. However, moderation analyses revealed that this was only when lifestyle-antisocial psychopathic traits were low, consistent with evidence suggesting that these two facets of psychopathic traits display opposing relationships with emotional reactivity. Anxiety did not show the predicted relationships with emotional capture effects. Findings show... (shrink)

The provision of mental health services to women has come sharply into focus for providers of secure psychiatric services in the UK. Women's services are being developed in response to the known risks of mixed-sex provision, and a growing appreciation of the ways that women in secure services can be further disadvantaged by their minority status. Our intention here is to present evidence and reflections to help inform this development. The evidence is drawn from our recent work in this field, (...) which includes carrying out a review of local mental health services for ‘difficult’ women, and developing and piloting a national training programme for staff working with women in secure services. The reflections we offer are informed by the conviction that taking social inequalities into account is central to making sense of women's mental health difficulties, and improving service responses to women's needs. While there are signs that many mental health workers in secure services are beginning to share these convictions, the challenge now is to provide the necessary authorization, training and support that will enable them to translate these understandings into empowerment practice with women. (shrink)

The objective of this study was to assess the beliefs of parents of youth soccer players about Chronic Traumatic Encephalopathy, concussion, and retirement from sport decisions and compare them to those of concussion-specialized clinicians. An electronic survey was completed by parents of youth club soccer players and concussion-specialized clinicians located in a large U.S. urban center. Parents believed more strongly in the causal relationship between concussions and CTE, and between CTE and harm than did clinicians. Parents who themselves had participated (...) in sport at a high level had more conservative beliefs than other parents about the number of concussions after which an athlete should retire from contact or collision sport. Results are discussed in the context of ethical risk communication between clinicians and parents. This includes the importance of communicating information about CTE to parents and youth athletes in an understandable way so that they can make informed choices about contact and collision sport participation. Further research is encouraged to evaluate approaches of communicating evidence about CTE to a diverse population of families of youth athletes. (shrink)

Queering Paradigms IVa: Insurgências queer ao Sul do equador, junto com o volume Queering Paradigms IV: South-North Dialogues on Queer Epistemologies, Embodiments and Activisms (Lewis et al. 2014), divulga de forma multilíngue pesquisas apresentadas no 4° Congresso Internacional Queering Paradigms (QP4), sediado no Rio de Janeiro, Brasil. Ambos os volumes compartilham o objetivo de analisar o status quo e os desafios para o futuro dos Estudos Queer a partir de uma perspectiva inter/multidisciplinar, concentrando-se sobre as relações entre os eixos Sul-Norte. (...) O presente livro oferece capítulos escritos em português e espanhol, línguas subalternas na academia global, visando a privilegiar vozes e conhecimentos do Sul. Os trabalhos reunidos neste volume insurgem contra a colonização epistemológica dos corpos que habitam o Sul global e apontam para os problemas que surgem quando a(s) Teoria(s) Queer do Norte são aplicadas sem adaptação a outros contextos. Além de violências epistemológicas, a falta de atenção ao que acontece ao sul do equador pode levar a uma paralização do debate queer. O convite que esses capítulos fazem é um desafio a olhar para onde não se costuma olhar e ouvir as vozes que não se costuma ouvir, de forma a devolver ao queer seu potencial de contestação. Queering Paradigms IVa: Insurgências queer ao Sul do equador, junto con el tomo Queering Paradigms IV: South-North Dialogues on Queer Epistemologies, Embodiments and Activisms (Lewis et al. 2014), difunde de forma multilingüe algunas de las investigaciones presentadas en el 4o Congreso Internacional Queering Paradigms (QP4), en Río de Janeiro, Brasil. Ambos tomos comparten el objetivo de analizar el estado actual y los desafíos para el futuro de los Estudios Queer desde una perspectiva inter/multidisciplinaria, concentrándose sobre las relaciones entre el eje Sur-Norte. El presente libro ofrece capítulos escritos en portugués y español, lenguas subalternas en la academia global, con la pretensión de privilegiar voces y conocimientos del Sur. Los trabajos reunidos en este tomo se insurgen contra la colonización epistemológica de los cuerpos que habitan el Sur global y apuntan a los problemas que surgen cuando la(s) Teoría(s) Queer del Norte son aplicadas sin adaptación a otros contextos. Además de las violencias epistemológicas, la falta de atención a lo que acontece al sur del Ecuador puede llevar a una paralización del debate queer. La propuesta de estos capítulos es un desafío a mirar para dónde no se suele mirar y a escuchar las voces que no se suelen escuchar, para devolverle al queer su potencial de contestación. (shrink)

Neither the Ancients nor the medieval philosophers were unaware of the problem of the plurality of languages, represented symbolically by the Biblical Tower of Babel. The sixteenth century, nevertheless, had to face the problem from perspectives that went beyond the traditional philosophical debate. The discovery of new territories, new languages, new natural beings without known denomination, as well as the proliferation of names for apparently the same thing, created a great problem of scientific communication precisely when this began to erect (...) like one of the essential values of the investigation of nature. The question about how to know nature became inseparable from the question about the best instrument to transmit natural knowledge. I propose here a review about how the utopian literature of sixteenth and seventeenth centuries echoed this problem about scientific communication, as well as some of the proposals coming from the own scientific practices. (shrink)

Based on a general review of international, representative tissue banking policies that were described in the medical, ethics, and legal literature, this paper reviews the range of standards, both conceptually and in existing regulations, relevant to four main factors:(1) commercialization, (2) confidentiality, (3) informed consent, and (4) quality of research. These four factors were selected as reflective of some of the major ethical considerations that arise in the conduct of tissue banking research. The authors emphasize that any policy or ethical (...) guidelines designed to regulate tissue bank research should address all four factors. Whenever this sort of research is conducted between several institutions or several countries, the paper suggests that the relevant entities work collaboratively to harmonize their standards. (shrink)

El artículo pretende analizar, a través de la historia, la cuestión de la patologización trans*, que ha contado y cuenta con una oposición bastante amplia por parte de diversos colectivos. El debate político de la cuestión (por medio de la petición de normativas y leyes que regulen determinados aspectos de la identidad) hace que una cuestión individual como es la identidad haya pasado a ser un tema colectivo. Que sea asunto colectivo hace que sea imposible desligar la biología de la (...) medicina, el derecho o la política. Es esta interdisciplinariedad lo que dota hoy en día a la cuestión trans* de tanta relevancia, tampoco exenta de polémica con otros movimientos sociales, como las redes sociales han venido mostrando últimamente. No obstante, es la gran visibilidad que ha obtenido por diferentes medios la cuestión trans* lo que la hace susceptible de múltiples análisis, que, como se ha dicho anteriormente, no se limitan a una única disciplina o a un único punto de vista. (shrink)

Professor d’Hoine claims that Proclus assigns a specific ontological function to the Form of Likeness in his Commentary on the Parmenides. According to d’Hoine, for Proclus, each individual must, qua individual striving to imitate the form, present a difference; this difference or unlikeness of one member of a coordinate kind to another, the plurality of participants in a Form, is Form’s by the Form of Unlikeness. And in a similar way, the Form of Likeness then guarantees the imitation of the (...) Form by the particular. I try to show that in other passages in Proclus’ oeuvre, likeness extends to include many more relationships than the Forms instantiation as a material particular. Hence, Likeness is not confined to this specific ontological function. (shrink)