The Monographs produced by the International Agency for Research on Cancer (IARC) apply rigorous procedures for the scientific review and evaluation of carcinogenic hazards by independent experts. The Preamble to the IARC Monographs, which outlines these procedures, was updated in 2019, following recommendations of a 2018 expert Advisory Group. This article presents the key features of the updated Preamble, a major milestone that will enable IARC to take advantage of recent scientific and procedural advances made during the 12 years since (...) the last Preamble amendments. The updated Preamble formalizes important developments already being pioneered in the Monographs Programme. These developments were taken forward in a clarified and strengthened process for identifying, reviewing, evaluating and integrating evidence to identify causes of human cancer. The advancements adopted include strengthening of systematic review methodologies; greater emphasis on mechanistic evidence, based on key characteristics of carcinogens; greater consideration of quality and informativeness in the critical evaluation of epidemiological studies, including their exposure assessment methods; improved harmonization of evaluation criteria for the different evidence streams; and a single-step process of integrating evidence on cancer in humans, cancer in experimental animals and mechanisms for reaching overall evaluations. In all, the updated Preamble underpins a stronger and more transparent method for the identification of carcinogenic hazards, the essential first step in cancer prevention. (shrink)

A leading scholar in the psychology of thinking and reasoning argues that the counterfactual imagination—the creation of "if only" alternatives to ...

Three experiments are reported which show that in certain contexts subjects reject instances of the valid modus ponens and modus tollens inference form in conditional arguments. For example, when a conditional premise, such as: If she meets her friend then she will go to a play, is accompanied by a conditional containing an additional requirement: If she has enough money then she will go to a play, subjects reject the inference from the categorical premise: She meets her friend, to the (...) conclusion: She will go to a play. Other contexts suppress the conditional fallacies. The first experiment demonstrates the effects of context on conditional reasoning. The second experiment shows that the inference suppression disappears when the categorical premise refers to both of the antecedents, such as: She meets her friend and she has enough money. In this case, subjects make both the valid inferences and the fallacies, regardless of the contextual information. The third experiment establishes that when subjects are given general information about the duration of a situation in which a conditional inducement was uttered, such as: If you shout then I will shoot you, they reject both the valid inferences and the fallacies. The results suggest that the interpretation of premises plays an even more central role in reasoning than has previously been admitted. Trois expériences montrent que dans certains contextes les sujets rejettent des instances valides de modus ponens et de modus tollens dans des énoncés conditionnels. Par exemple, quand une prémisse conditionnelle comme: Si elle rencontre son ami, alors elle ira jouer, est accompagnée par une phrase contenant une condition supplémentaire: Si elle a assez d'argent, alors elle ira jouer, les sujets rejettent l'inférence liant la prémisse catégorielle: Elle rencontre son ami, à la conclusion: Elle ira jouer. D'autres contextes éliminent également les inférences conditionnelles fallacieuses. La premiére expérience démontre l'effet du contexte sur la raisonnement conditionnel. La deuxiéme expérience montre que la suppression de l'inférence disparait quand la prémisse catégorielle fait référence aux deux antécédants, comme: Elle rencontre son ami et elle a assez d'argent. Dans ce cas, les sujets font aussi bien les inférences valides et fallacieuses, quelle que soit l'information contextuelle. La troisiéme expérience établit que quand l'on donne aux sujets des informations générales à propos de la durée d'une situation dans laquelle une conditionnelle a été prononcée, comme Si tu cries, alors je te tire dessus, ils rejettent autant les inférences valides que les inférences fallacieuses. Ces résultats suggèrent que l'interprétation des prémisses joue un rŏle encore plus central dans le raisonnement que l'on admettait auparavant. (shrink)

Two experiments investigated inferences based on suppositions. In Experiment 1, the subjects decided whether suppositions about individuals' veracity were consistent with their assertions—for example, whether the supposition “Ann is telling the truth and Beth is telling a lie”, is consistent with the premises: “Ann asserts: I am telling the truth and Beth is telling the truth. Beth asserts: Ann is telling the truth”. It showed that these inferences are more difficult than ones based on factual premises: “Ann asserts: I live (...) in Dublin and Beth lives in Dublin”. There was no difference between problems about truthtellers and liars, who always told the truth or always lied, and normals, who sometimes told the truth and sometimes lied. In Experiment 2, the subjects made inferences about factual matters set in three contexts: a truth-inducing context in which friends confided their personality characteristics, a lie-inducing context in which business rivals advertised their products, and a neutral context in which computers printed their program characteristics. Given the supposition that the individuals were lying, it was more difficult to make inferences in a truth-inducing context than in the other two contexts. We discuss the implications of our results for everyday reasoning from suppositions, and for theories of reasoning based on models or inference rules. (shrink)

Semantics is a bridge discipline between linguistics and philosophy; but linguistics student are rarely able to reach that bridge, let alone cross it to inspect and assess the activity on the other side. Professor Kempson's textbook seeks particularly to encourage such exchanges. She deals with the standard linguistic topics like componential analysis, semantic universals and the syntax-semantics controversy. But she also provides for students with no training in philosophy or logic an introduction to such central topics in the philosophy of (...) language as logical form, truth, speech acts, analyticity, entailment and presupposition. The exposition throughout is deliberately argumentative rather than descriptive, introducing the student step by step to the major problems in theoretical semantics. Special emphasis is placed on the need to consider individual arguments within the overall perspective of semantics as an integral part of general linguistic theory. Written primarily as a textbook for undergraduates and graduates in linguistics departments, this book will also be useful to undergraduates in philosophy and in psychology where linguistics is a part of their course. (shrink)

In the opening sections of this paper, we defined ambiguity in terms of distinct sentences (for a single sentence-string) with, in particular, distinct sets of truth conditions for the corresponding negative sentence-string. Lexical vagueness was defined as equivalent to disjunction, for under conditions of the negation of a sentence-string containing such an expression, all the relevant more specific interpretations of the string had also to be negated. Yet in the case of mixed quantification sentences, the strengthened, more specific, interpretations of (...) some such positive string are not all of them necessarily implied to be false if the corresponding negative sentence-string is asserted. On the contrary, as we saw in section 6, a negative sentence-string can be used to deny one of the more specific interpretations of the corresponding positive string without also denying other weaker interpretations of that same string. One might therefore argue that the only empirical evidence availble for assessing quantified sentences suggests clearly that these sentence-strings are ambiguous. Indeed logicians, many of whom restrict their attention to propositions, MUST recognise logical ambiguity at this point. For the contextualisation of the negative sentences in section 6 showed that it was possible to assert the falsity of some proposition P expressed by the sentence S while asserting a further proposition which was compatible with the truth of S. However the corresponding conclusion that such sentence-strings are sententially ambiguous is not a necessary conclusion for the linguist: for the alternative account of postulating a single semantic representation plus a set of semantic procedures is also compatible with the negation evidence. Moreover we have seen independent reasons for thinking that if sentential ambiguity is assumed to be in one-to-one correspondence with what we should now call logical ambiguity, a considerable body of generalisations is lost. For the maximal ambiguity account, it should be recalled, is committed to assigning at least thirteen distinct propositions and hence thirteen distinct sentence outputs for every sentence-string containing no more than two quantifiers, for three out of the four interpretations originally outlined in this paper can be understood with each numeral taken either in an ’exactly’ sense or in an ’at least’ sense. Moreover there is no explanation of why just these interpretations are available-they are merely an arbitrary list, no more connected than are the two interpretations of John saw her duck, with no reason to predict that the ambiguity would carry over from language to language. If then it is granted that an ambiguity account fails to capture appropriate generalisations, only two alternative accounts of mixed quantification sentence-strings remain viable-an analysis proposing an initial co-ordinate logical form like the logical form III, which is the strongest form compatible with each of the propositional interpretations of sentence-string Two examiners marked six scripts, and the radically weak form in which only existential quantification (both over sets and over members of those sets) is invoked. Since there are strong arguments to suggest that the procedures which both analyses require are semantic, there seems no reason not to adopt the radical vagueness account, with its considerably greater simplicity. (shrink)

: In this paper, I consider some issues concerning Hume’s epistemology of testimony. I’ll particularly focus on the accusation of reductivism and individualism brought by scholars against Hume’s view on testimonial evidence, based on the tenth section of his An enquiry concerning human understanding. I first explain the arguments against Hume’s position, and address some replies in the literature in order to offer an alternative interpretation concerning the way such a defense should go. My strategy is closely connected with Hume’s (...) notion of virtue and the role it plays in his epistemology, mainly as presented in his A treatise of human nature. I address the problem of how the section “Of miracles” in the Enquiry must be properly understood, as several misunderstandings of Hume’s epistemology of testimony emerge partially from the particular character and aim of that section. Resumen: En este artículo, considero algunas cuestiones relacionadas con la epistemología del testimonio de David Hume. El eje central será la acusación de reductivismo e individualismo de los estudiosos en contra de la opinión de Hume sobre la evidencia testimonial. Dicha acusación se basa en su tratamiento de los reportes sobre hechos milagrosos, presente en la sección X de su Investigación sobre el entendimiento humano. En primer lugar, se abordan los argumentos en contra de la posición de Hume y algunas respuestas en la literatura reciente, para luego ofrecer una interpretación alternativa con respecto a la forma en que debería articularse esa defensa. Mi estrategia está estrechamente relacionada con la noción de virtud de Hume y el papel que desempeña en su epistemología, principalmente como se presenta en su Tratado de la naturaleza humana. Finalmente, abordaré el problema relacionado con la forma en que debe entenderse correctamente la sección “Of miracles” de la Investigación, ya que varios malentendidos sobre la epistemología del testimonio de Hume emergen parcialmente del carácter particular y el objetivo de dicho ensayo. (shrink)

This dynamic collection provides an overview of the relationship between linguistic form and interpretation as exemplified by the most influential of these ...

From the stance of cognitive developmental theories, claims that general g is an entity of the mind are compatible with notions about domain-general development and age-invariant individual differences. Whether executive function is equated with general g or fluid g, research into the mechanisms by which development occurs is essential to elucidate the kinds of environmental inputs that engender effective intervention. (Published Online April 5 2006).

This groundbreaking collection, the most thorough treatment of the philosophy of linguistics ever published, brings together philosophers, scientists and historians to map out both the foundational assumptions set during the second half of ...

This index gives the location of each reference in Spinoza's Ethics to every axiom, definition, corollary, scholium, and proposition in that work.

In this paper I discuss two views that focus on the natural environment, namely (1) a western or “W” view (hereafter W) basedloosely on the kind of liberal outlook offered by John Rawls in A Theory of Justice and (2) a primal or “P” view (hereafter, P) stemming from environmental teachings of primal peoples. I suggest that while the W tradition has produced many truly helpful and comfortable amenities, it is nevertheless oriented toward commitments to resource acquisition and “detached” objectivity (...) of sorts that could ultimately lead human beings down paths of predictable and tragic destruction. I conclude that P needs to be seriously considered and, where possible, utilized to remold W to achieve a view with maximal environment-preserving possibilities. (shrink)

The authors outline a theory of conditionals of the form If A then C and If A then possibly C. The 2 sorts of conditional have separate core meanings that refer to sets of possibilities. Knowledge, pragmatics, and semantics can modulate these meanings. Modulation can add information about temporal and other relations between antecedent and consequent. It can also prevent the construction of possibilities to yield 10 distinct sets of possibilities to which conditionals can refer. The mental representation of a (...) conditional normally makes explicit only the possibilities in which its antecedent is true, yielding other possibilities implicitly. Reasoners tend to focus on the explicit possibilities. The theory predicts the major phenomena of understanding and reasoning with conditionals. (shrink)

Four studies show that observers and readers imagine different alternatives to reality. When participants read a story about a protagonist who chose the more difficult of two tasks and failed, their counterfactual thoughts focused on the easier, unchosen task. But when they observed the performance of an individual who chose and failed the more difficult task, participants' counterfactual thoughts focused on alternative ways to solve the chosen task, as did the thoughts of individuals who acted out the event. We conclude (...) that these role effects may occur because participants' attention is engaged when they experience or observe an event more than when they read about it. (shrink)

People judge that an individual who attempts to harm someone but fails should be blamed and punished more when they imagine how things could have turned out worse, compared to when they imagine how things could have turned out the same, or when they think only about what happened. This moral counterfactual amplification effect occurs when people believe the protagonist had no reason for the attempt to harm, and not when the protagonist had a reason, as Experiment 1 shows. It (...) occurs for intentional failed attempts to harm and also for accidental near-misses, as Experiment 2 shows, but not for failed attempts in which the harm occurs anyway by another cause, for both general judgments about the event and specific judgments about the individual's actions, as Experiments 3 and 4 show. The implications for understanding the role of counterfactual thoughts in moral judgement are discussed. (shrink)

Much has changed in maternal-fetal medicine since the early 2000s, when the previous ethical frameworks for fetal therapy trials were established. We applaud Hendriks and colleagues for taking on t...

We report two Experiments to compare counterfactual thoughts about how an outcome could have been different and causal explanations about why the outcome occurred. Experiment 1 showed that people generate counterfactual thoughts more often about controllable than uncontrollable events, whereas they generate causal explanations more often about unexpected than expected events. Counterfactual thoughts focus on specific factors, whereas causal explanations focus on both general and specific factors. Experiment 2 showed that in their spontaneous counterfactual thoughts, people focus on normal events (...) just as often as exceptional events, unlike in directed counterfactual thoughts. The findings are consistent with the suggestion that counterfactual thoughts tend to focus on how a specific unwanted outcome could have been prevented, whereas causal explanations tend to provide more general causal information that enables future understanding, prediction, and intervention in a wide range of situations. (shrink)

When people think about how a situation might have turned out differently, they tend to imagine counterfactual alternatives to their actions. We report the results of three experiments which show that people imagine alternatives to actions differently when they know about a reason for the action. The first experiment ( n = 36) compared reason - action sequences to cause - effect sequences. It showed that people do not imagine alternatives to reasons in the way they imagine alternatives to causes: (...) they imagine an alternative to an action more than an effect, and to a cause more than a reason. The second experiment ( n = 214) and the third experiment ( n = 190) both show that different sorts of reasons have different sorts of effects on how people imagine alternatives to actions. People imagine an alternative to an action (the protagonist went to a ball) less often when they know the reason for the action was an obligation (he had to participate in fundraising) compared to when they know about a weaker reason (he wanted to meet a famous violinist) or no reason. The second experiment shows the effect for a social obligation and the third experiment replicates and extends it to a health obligation. We interpret the results in terms of the possibilities that people keep in mind about actions and their reasons. (shrink)